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김주승,박민철 대한고유수용성신경근촉진법학회 2018 PNF and Movement Vol.16 No.3
Purpose: The purpose of this study was to investigate whether the respiratory function of patients with stroke was different on the ground and under water. Methods: We recruited 14 adults who had experienced a stroke (12 male, 2 female) for our study. We measured forced vital capacity, forced expiratory volume at one second, maximum inspiratory pressure, and maximum expiratory pressure when the participants breathed on the ground and under water. On the ground, the participants were safely supported using a table and chair and were measured in a standing posture. For measuring under water, the participants were immersed in water in a standing position to clavicle height. The participants were measured while standing, and the assistant supported them when they needed help. The collected data were analyzed by a paired t-test. Results: Forced vital capacity and forced expiratory volume at one second were significantly lower in water than on the ground when breathing at maximum. Maximum inspiratory pressure was not significantly different when standing on the ground or in water, but maximum expiratory pressure was significantly higher in water than on the ground. Conclusion: It has been confirmed that the hydrostatic pressure affecting stroke patients immersed in water affects the forced expiratory volume at one second while reducing the forced vital capacity and increasing the maximum expiratory pressure.
Investigation effect of solution pH on adsorption behavior of proteins on solid/liquid interface
김주승,김응석,이정인,임진익,이우걸 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Interaction of proteins to material is of critical importance to determine the biocompatibility and consequently the success of implanted materials. The adsorbed protein molecules modulate the subsequent cellular and tissue responses. Therefore, understanding interfacial behavior of protein molecules will be highly useful to anticipate the material performance in biological environment. In this study, we analyzed the adsorption behavior of 3 different globular proteins on calcium phosphate coating under different solution pH. The adsorption kinetics were measured using ATR-FTIR and adsorbed mass was quantified using a protein assay. The infrared spectroscopic analysis revealed that solution pH strongly affect the interfacial behavior of protein molecules and the conformation of protein changes via interaction with surface.
Preparation of porous chitosan scaffold via bio-friendly synthetic method
김주승,김응석,이정인,김지혜,이우걸 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Scaffold is essential in tissue engineering and has a structural object that supports 3D tissue regeneration. A variety of materials have been used for the preparation of scaffolds. Among them, chitosan, a natural polymer obtained from the shells of crustaceans and widely used for the fabrication of scaffolds. In this study, we aims at developing a method for scaffold preparation via a bio-friendly process in order to minimize cytotoxic effects of synthetic scaffolds. The physical properties recovery and morphology, and chemical states of the prepared scaffold were examined using SEM, EDX, FT-IR, goniometer. The cytocompatibility of the scaffold was evaluated using osteoblastic MG63 cells. <sup>**</sup>This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717)
Poly(3-hexylthiophene)의 PL 발광 메카니즘에 관한 연구
김주승,서부완,구할본 한국전기전자재료학회 2001 전기전자재료학회논문지 Vol.14 No.2
We studied the optical properties of poly(3-hexylthiophene) for applying to the emitting material of organic electro luminescent device. The infrared spectrum and NMR of synthesized polymer gave good evidence for the conjugation of 3-hexylthiophene monomer unit. We confirmed that poly(3-hexylthiophene) contains the HT(head-to-tail)-HT(head-to-Tail) linkage larger than 65% based on NMR analysis. FTIR and raman spectroscopy show that poly(3-hexylthiophene) has two main vibration levels which have an energy about 0.18eV and 0.36eV. Electronic absorption spectra shifted to the shorter wavelength with increasing temperature, which is related to a conformational transition of the polymer. Photoluminescence spectrum generated at low temperature(10K) is separated at 669nm, 733nm and 812nm that it's because of phonon energy generated from the lattice vibration.
전기-광 변환소자 응용을 위한 적색 유기 EL 소자의 광변조 특성
김주승,구할본,Kim, Ju-Seung,Gu, Hal-Bon 한국전기전자재료학회 2005 전기전자재료학회논문지 Vol.18 No.6
We fabricated red organic light emitting diodes(OLEDs) utilizing tis(8-hydroxyquinoline) aluminum $(Alq_3)$ doped with $5\%$ of (4-(dicyanomethylene)-2-i-propyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran) (DCJTI) and investigated the driving and modulation characteristics for applying to the electro-optical conversion device. To improve the driving characteristics of red OLEDs, 3 V of offset voltage, which is equal to the turn on voltage, Is applied to the device. Offset voltage enhanced the optical EL output and reduced the rise time of EL waveforms of red OLEDs, and hence the cutoff frequency is increased with increasing applied voltage. The optical pulse of 100 MHz has been obtained from red OLEDs. Therefore, we confirmed that the red OLEDs can be applied to the fields of optical communication as an electro-optical conversion device.
Synthesis of apatitic thin films on poly(L-lactide-co-caprolactone) scaffold
김주승,김응석,이정인,김지혜,이우걸 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Apatite is a compound widely used in tissue repair purposes, hard tissue in particular. Various types of apatitic compounds have been introduced. However, its weak mechanical strength limits further utilization. One of the means to overcome this problem is to use it as a surface modifying agent. In this study, we synthesized an apatitic thin film on a poly(L-lactide-co-caprolactone) scaffold in order to improve biocompatibility. The physical and chemical properties of the films were analyzed using SEM, EDX, and goniometer. The bioactivity of films was examined using osteoblast-like MG63 cells.
Fabrication of alendronic acid-loaded PLCL scaffolds for hard tissue repair
김주승,김응석,이정인,임진익,이우걸 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.1
Caprolactone and L-lactide are basic materials for the preparation of various biomaterials. We synthesized poly(L-lactide-co-caprolactone) (PLCL) using these two monomers. PLCL is a biodegradable polymer and can be readily fabricated into various structures. Alendronic acid is a therapeutic agent widely used for repair of various bone-related diseases. In this study we investigated the effects of incorporation of alendronic acid in PLCL scaffold on physical and biological properties. Various analytical methods, including SEM, EDX, and FT-IR, were utilized to examine the physicochemical properties of the scaffolds. In vitro assessments were performed to analyzed the cellular responses using an osteoblastic cell-line. <sup>**</sup>This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717)
Isolation and analysis of collagen from fish and porcine skin
김주승,이우걸,김준영,임효경,신수인,조성일 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.1
Collagen is the major protein, approximately 30%, of human proteins. Collagen has been mostly extracted from the skin of bovine or porcine but its use has been limited due to bovine spongiform encephalopathy and the foot-and-mouth disease. Therefore, researchers have attempted to using fish skin and bone these days. We isolated of collagen from skin and bone of chub mackerel and carp and porcine skin. Extraction yield and characterization of the isolated collagen were performed.