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      • KCI등재

        Retrospective clinical study of an implant with a sandblasted, large-grit, acid-etched surface and internal connection: analysis of short-term success rate and marginal bone loss

        Lee, Jae-Wang,An, Jun Hyeong,Park, Sang-Hoon,Chong, Jong-Hyon,Kim, Gwang-Seok,Han, JeongJoon,Jung, Seunggon,Kook, Min-suk,Oh, Hee-Kyun,Ryu, Sun-Youl,Park, Hong-Ju Korean Association of Maxillofacial Plastic and Re 2016 Maxillofacial Plastic Reconstructive Surgery Vol.38 No.-

        Background: The purpose of this retrospective study was to evaluate the clinical utility of an implant with a sandblasted, large-grit, acid-etched (SLA) surface and internal connection. Methods: Six patients who received dental implants in the Department of Oral and Maxillofacial Surgery, Chonnam National University Dental Hospital, were analyzed by factors influencing the success rate and marginal bone loss. Factors included patient's age, sex, implant installation site, whether bone graft was done, type of bone graft materials, approaching method if sinus lift was done, and the size of the fixture. In addition, the marginal bone loss was analyzed by using a radiograph. Results: All implants were successful, and the cumulative survival rate was 100 %. Average marginal bone loss of 6 months after the installation was 0.52 mm and 20 months after the functional loading was 1.06 mm. Total marginal bone resorption was 1.58 mm on average. There was no statistically significant difference in mesial and distal marginal bone loss. Conclusions: The short-term clinical success rate of the implant with an SLA surface and internal connection was satisfactory. Moreover, the marginal bone loss was also consistent with the implant success criteria.

      • KCI등재

        한계고령화율(고령화의 한계기술대체율) 개념을 이용한 농촌지역 경제-복지의 보완관계 모색 연구

        박길환 한국농촌경제연구원 2015 농촌경제 Vol.38 No.3

        Concerning accelerated rural population aging, this article introduces the concept of the marginal rate of population aging (MRPA) drawing on the economics and welfare literatures. It is defined as the marginal rate of technical substitution between aggregate capital and “aging” aggregate labor. The traditional approach to (rural or agricultural) production was based on the presumption that aging does not affect production. However, the physical and mental capability of working decreases as population becomes aged. The externality of this declining capability needs to be reflected in aggregate productions and to be treated more significantly as population becomes more aged. After a review of the trends and spatial distributions of aging in Korea, a rural town is selected in this study as a case area whose parcel-level spatial data is analyzable in terms of MRPA. This exploratory analysis is focused on whether rural economic and social welfare may become complementary in rural aggregate production with MRPA if a design of the lifetime mortgage of farming assets (LMFA) leads to large-scale production and welfare improvements.

      • KCI등재

        Implicit Treatment of Technical Specifi cation and Thermal Hydraulic Parameter Uncertainties in Gaussian Process Model to Estimate Safety Margin

        FYNAN DOUGLAS ANDREW,안광일 한국원자력학회 2016 Nuclear Engineering and Technology Vol.48 No.3

        The Gaussian process model (GPM) is a flexible surrogate model that can be used fornonparametric regression for multivariate problems. A unique feature of the GPM is that aprediction variance is automatically provided with the regression function. In this paper,we estimate the safety margin of a nuclear power plant by performing regression on theoutput of best-estimate simulations of a large-break loss-of-coolant accident with samplingof safety system configuration, sequence timing, technical specifications, and thermalhydraulic parameter uncertainties. The key aspect of our approach is that the GPMregression is only performed on the dominant input variables, the safety injection flow rateand the delay time for AC powered pumps to start representing sequence timing uncertainty,providing a predictive model for the peak clad temperature during a reflood phase. Other uncertainties are interpreted as contributors to the measurement noise of the codeoutput and are implicitly treated in the GPM in the noise variance term, providing localuncertainty bounds for the peak clad temperature. We discuss the applicability of theforegoing method to reduce the use of conservative assumptions in best estimate plusuncertainty (BEPU) and Level 1 probabilistic safety assessment (PSA) success criteria definitionswhile dealing with a large number of uncertainties.

      • KCI등재

        중소기업과 대기업의 군집현상에 대한 실증분석: 한국의 해외법인투자 기업자료를 중심으로

        김진희 ( Jinhee Kim ),허정 ( Jung Hur ) 한국산업조직학회 2016 産業組織硏究 Vol.24 No.4

        본 논문은 2008년부터 2013년까지 한국의 제조업분야 중소기업과 대기업의 해외법인투자를 외연적 한계 (해외자회사 수)와 내연적 한계 (해외투자금액)로 나누어, 해외법인투자의 군집현상에 대해 기업수준 자료를 이용, 실증분석을 시도하였다. 본 논문의 주요 결과는 다음과 같다. 우선, 세계지역을 구분하지 않았을 때, 중소기업과 대기업의 전세계 대상 해외직접투자에 있어서, 외연적 한계 및 내연적 한계 모두에서 군집현상이 나타났다. 그러나, 세계지역을 북미유럽과 아시아 지역으로 구분하였을 때는, 대기업과 달리 중소기업들은 북미유럽지역보다는 아시아 지역에 편중된 군집효과가 있음이 드러났다. 이러한 실증 분석 결과는 한국 기업들의 “이질적인” 글로벌 생산-공급 네트워크가 발생하고 있음을 시사하고 있다. In this paper, we attempt to empirically analyze the overseas agglomerations of Korean firms, by dividing the extensive margin (numbers of foreign affiliates per parent firm) and intensive margin (average amounts of foreign direct investments per affiliate) of the firms` foreign direct investment for the period of 2008 to 2013. The main results are as follows. First, without a consideration on the destinations of the foreign direct investments, we found the agglomeration effects for both the extensive and intensive margins of the foreign direct investment, regardless the size of firms. Second, however, when we divide the world into Asia and North American-Europe as the destination regions, unlike the large firms, Asia-clustered agglomeration effects are found in the sample of small-and-medium firms. These findings imply that the heterogeneous networks of global production-supply chains have been occurring among Korean firms.

      • KCI등재

        생보사 책임준비금의 평가를 위한 통계적 추정모형에 관한 연구

        이광봉,이창수,정창호 한국리스크관리학회 2003 리스크 管理硏究 Vol.14 No.1

        현재 국내 생보사의 책임준비금 산출을 위하여 적용되는 위험율은 업계 전체의 자료를 기초로 하여 통계적으로 작성되는 표준위험률로서 실제로 구현되는 위험률의 불확실성을 감안한 안전할증을 반영하고 있다. 그러나 예정위험률을 일괄적으로 할증하는 방식은 할증에 따른 책임준비금의 증가효과가 경과 순보험료 총액에 비례적으로 작용하게 되어 상대적으로 대형 보험사가 소형 보험사에 비해 책임준비금을 과다하게 적립하는 것을 요구하게 되는 문제점을 초래하게 된다. 본 연구는 개별 생보사의 위험정도를 준비금 적립기준에 반영할 수 있는 통계적 추정모형을 설정하여 현행 방식과 추정모형에 따른 책임준비금을 산출하고 그 결과를 분석하였다. 분석결과는 보유계약건수가 일정수준을 초과하는 경우 보유계약건수가 증가할수록 대수의 법칙이 원활하게 작용함으로써 통계적 추정모형에 의한 책임준비금의 규모는 현행 순보험료식준비금보다 적은 것으로 나타났다. 특히 여성계약자의 경우 남성계약자보다 감소비율이 큰 것으로 나타나 여성의 예정위험률의 할증이 남성에 비하여 상대적으로 큰 것으로 분석되었다. The existing system of policy reserve valuation in Korea requires some safety margins to the rates of mortality originally derived from past mortality experience. However, the amount of appropriate safety margins is very difficult to measure and thus is often set in the somewhat arbitrary fashion. Further, the process does not consider the risk reduction effect through pooling arrangements. This study first recognizes that the law of large numbers operates in the process of reserve valuation as it works in the process of providing insurance products to the public at the outset. Based on this nature of reserve valuations, it then, derives a statistical inference model for reserve valuation and tests the model through sirnulated data and empirical data. Comparing the test results to the results derived from the current valuation method, this study suggests the following implications: (1) as the number of in-force business increases, the level of policy reserves calculated from the model is getting lower through the operation of the law of large numbers, (2) model policy reserves are consistently smaller than those of the current valuation method for all the life insurers investigated and at every level of various confidence intervals, (3) the difference between the two methods mentioned in (2) is remarkably conspicuous for the case of women policyholders, suggesting that the safety margin applied to women mortality rates is relatively bigger than the margin added to men mortality rates.

      • KCI등재

        자궁경부 상피내종양치료에서의 환상투열요법 (LLETZ)의 임상적 효용성

        전혜원 ( Hye Won Jeon ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.12

        목적 : 본 연구는 자궁경부 상피내종양의 평가 및 치료에 있어서의 LLETZ 효용성과 LLETZ 후 잔류병변에 영향을 주는 위험인자에 대해 알아보고자 시행하였다. 연구 대상 및 방법 : 1998년 9월부터 2001년 8월까지 자궁경부질환으로 보라매병원 산부인과 외래를 방문하여 LLETZ를 시행받은 환자 56명 대상으로 후향적으로 시행하였다. LLETZ 후 잔류종양은 추후 실시한 자궁적출술 조직병리검사에서나 추적검사 중 다시 시행한 조직검사에서 상피내종양 Objective : This study was performed to assess the efficacy of large loop excision of transformation (LLETZ) and to evaluate of clinicopathological factors with the probability of residual disease. Methods : Retrospective study was performed in 56 patient

      • Composite large margin classifiers with latent subclasses for heterogeneous biomedical data

        Chen, Guanhua,Liu, Yufeng,Shen, Dinggang,Kosorok, Michael R. Wiley Subscription Services, Inc., A Wiley Company 2016 Statistical analysis and data mining Vol.9 No.2

        <P>High‐dimensional classification problems are prevalent in a wide range of modern scientific applications. Despite a large number of candidate classification techniques available to use, practitioners often face a dilemma of choosing between linear and general nonlinear classifiers. Specifically, simple linear classifiers have good interpretability, but may have limitations in handling data with complex structures. In contrast, general nonlinear classifiers are more flexible, but may lose interpretability and have higher tendency for overfitting. In this paper, we consider data with potential latent subgroups in the classes of interest. We propose a new method, namely the composite large margin (CLM) classifier, to address the issue of classification with latent subclasses. The CLM aims to find three linear functions simultaneously: one linear function to split the data into two parts, with each part being classified by a different linear classifier. Our method has comparable prediction accuracy to a general nonlinear classifier, and it maintains the interpretability of traditional linear classifiers. We demonstrate the competitive performance of the CLM through comparisons with several existing linear and nonlinear classifiers by Monte Carlo experiments. Analysis of the Alzheimer's disease classification problem using CLM not only provides a lower classification error in discriminating cases and controls, but also identifies subclasses in controls that are more likely to develop the disease in the future.</P>

      • SCOPUSKCI등재

        순차적 복합 림프종 2예

        최민지 ( Min Jee Choi ),김정은 ( Jung Eun Kim ),오신택 ( Shin Tak Oh ),조백기 ( Baik Kee Cho ),박현정 ( Hyun Jeong Park ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.8

        It is uncommon that two phenotypically different lymphomas develop in the same person, and especially in the skin. Composite lymphoma is defined as two distinctly demarcated types of non-Hodgkin`s lymphoma (NHL) or its association with Hodgkin`s lymphoma (HL) within a single organ or tissue. Discordant lymphoma is defined as two types of NHL or the association of HL with NHL at different anatomic sites in the same person. Sequential lymphoma and simultaneous lymphoma are defined as two different types of lymphoma that occur in the same person at different times and at the same times, respectively. We herein report on two cases of sequential composite lymphomas that were limited to the skin. A 57-year-old woman who had had been diagnosed with HL at the face had been treated with chemotherapy for 1.5 years. 6 months later, the patient revisited the dermatologic clinic of our hospital for a one-month history of erythematous nodules on her chest and upper extremities. Punch biopsy was performed and the pathologic diagnosis was mantle cell lymphoma. She refused further treatment. A 68-year old woman, who had been diagnosed as having extranodal marginal zone B cell lymphoma, had been treated with chemotherapy and radiation therapy for one year. After one year, she revisited dermatologic clinic of our hospital for a several-month history of erythematous nodules on her extremities. Punch biopsy from the lesion was performed and the pathologic diagnosis was cutaneous diffuse large B cell lymphoma, the leg type. She was scheduled for chemotherapy (rituximab with cyclophosphamide, adriamycin, vincristine and prednisolone (R-CHOP)). To the best of our knowledge, our cases are the first such cases in the Korean dermatologic literature. (Korean J Dermatol 2009;47(8):918~924)

      • KCI등재

        Two Cases of Diffuse Large B-Cell Lymphomas in the Cervical Lymph Nodes in Patients with Low-Grade Gastric Marginal Zone B-cell Lymphoma (MALT Lymphoma)

        정지훈,정훈용,윤환,이재광,강지훈,전성진,박영수,김진호 대한소화기내시경학회 2013 Clinical Endoscopy Vol.46 No.3

        It is well known that gastric mucosa-associated lymphoid tissue (MALT) lymphomas are associated with Helicobacter pylori infection and have a good prognosis. However, although rare, these low-grade lymphomas transform to the high-grade diffuse large B-cell lymphomas (DLBCLs) which are thought to be the important cause of death in patients with MALT lymphoma. We report two cases of DLBCLs in the cervical lymph nodes that occurred 10 years and 1.5 years after diagnosing low-grade gastric MALT lymphomas.

      • SCIESCOPUSKCI등재

        CRYSTAL B(λ) IN B(∞) FOR G<sub>2</sub> TYPE LIE ALGEBRA

        Kim, Min Kyu,Lee, Hyeonmi Korean Mathematical Society 2014 대한수학회지 Vol.51 No.2

        A previous work gave a combinatorial description of the crystal B(${\infty}$), in terms of certain simple Young tableaux referred to as the marginally large tableaux, for finite dimensional simple Lie algebras. Using this result, we present an explicit description of the crystal B(${\lambda}$), in terms of the marginally large tableaux, for the $G_2$ Lie algebra type. We also provide a new description of B(${\lambda}$), in terms of Nakajima monomials, that is in natural correspondence with our tableau description.

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