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구입경로가 다른 두 종류의 육미지황탕을 투여한 흰쥐의 혈액분석연구
전성진,이선동,박해모,최종환,이현우,Jeon, Seong-Jin,Lee, Sun-Dong,Park, Hae-Mo,Choi, Jong-Hhan,Lee, Hyean-Woo 대한예방한의학회 2005 대한예방한의학회지 Vol.9 No.2
Traditional herbal medicine is widely used among the Korean people, and other eastern Asian countries employ similar therapies as well. In recent years, due to increasing interest in herbal medicine, many researches have been made on the toxicity and adverse drug reactions of herbal medications. Through private and public media, there have been many opinions that taking herbal medicine is very harmful, especially, to liver and kidney. We face upon evaluation of herbal medication, safe, and efficacy. Furthermore, we need to control quality of herbs. This study aims to verify the evidence that taking herbal medicine will yield equal reaction in 2 lab animal groups (A and B). One frequently prescribed herbal medication, Yugmijihwangtang, was used to test the evaluation of quality on lab animals (SD-Rat). There were no significant differences in body, visceral weight, and serum analysis test results after herbal medication for 1 month. But, AST and ALT scores were raised in 2 subjects in group A (over reference range). It seems to be an adverse drug reaction, and this finding was restricted in group A herbal medicine. These results suggest that we need to qualify herbal plants in Korea, and study which herbs would cause specific reactions in human.
레일레이 감쇄 채널에서 타이밍 또는 위상 오류를 갖는 혼합 간섭 제거 기법의 성능 분석
전성진,박상규 한국통신학회 2000 韓國通信學會論文誌 Vol.25 No.12
이 논문에서는 레일레이 감쇄 채널에서 타이밍 또는 위상 오류를 갖는 혼합 간섭 제거 기법을 이용한 DS/CDMA 시스템의 평균 비트 오류 확률을 분석한다. 유도한 결과를 타이밍 또는 위상 오류를 갖는 일반 상관 수신기의 평균 비트 오류 확률과 비교 분석한다. 평균 비트 오류 확률은 정규 근사법을 이용하여 유도하며, 칩 시간에 대한 타이밍 오류의 비, 위상 오류의 정도, Eb/No에 따라 혼합 간섭 제거 기법을 이용한 수신기의 성능을 분석한다. 혼합 간섭 제거 기법을 이용한 수신기의 평균 비트 오류 확률은 타이밍 또는 위상 오류에 의해 증가하나 타이밍 또는 위상 오류가 작은 경우 오류가 없는 일반 상관 수신기에 비해 성능이 크게 개선된다.
사물탕의 용량별 투여가 임신 랫드와 태자에 미치는 독성학적 연구
전성진,신헌태,김경태,박해모,이선동,Jeon, Sung-Jin,Shin, Heon-Tae,Kim, Kyung-Tae,Park, Hae-Mo,Lee, Sun-Dong 대한예방한의학회 2010 대한예방한의학회지 Vol.14 No.3
Objective : Samulatang (herbal description) is much used for women's disease in Korean Traditional Medicine. The aim of this study is to evaluate reproductive toxic effect by Samultang in pregnant rats and fetuses, and ascertain a dose-response relationship Method : Pregnant Sprague-Dawley rats were administered with the Samultang at single, double and quadruple dose for 20 days, orally. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Live fetuses of gestation were randomly selected and fixed in 95% ethanol. Fetuses were stained with alcian blue and alizarin red S. We observe maternal body weight,, index associated pregnancy, and skeletal malformations in fetus Result : Maternal body weight of Samultang treated group has increased, side effect was not found in maternal body compared to that of control group. There were no significant difference in internal and reproductive organs. Double concentration administered group had lowest value in number of implantation, live fetuses, implantation rate and delivery rate, Also double concentration administered group showed higher early and late resorption rate than the other group. But, these are not significant. In the sex ratio, number of females, bigger than number of males in all Samultang administered groups. The fetuses of dams treated with Samultang didn't showed external and skeletal malformation. Vertebral and sternal variations were observed in single, double and quadruple concentration administered group but, compared to the control, those variations were insignificant. There were no significant changes in number of ribs, cervical, thoracic, lumber, sacral and caudal vertebrae Conclusion : Samultang is not expected to affect on pregnant rats and fetus about maternal body weight and number of live fetuses. There were no significant changes in organ weight, reproductive organs. Although skeletal variations were showed in vertebrae and sternum, treated groups were shown insignificant changes in skeletal variation
Mycobacterium fortuitum에 의한 피부감염증
전성진,서기석,김상태,유경식,박인달,장명웅 ( Seong Jin Jeon,Kee Suck Suh,Sang Tae Kim,Gyung Sig Yoo,In Dal Park,Myung Woong Chang ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.5
We report a case of cutaneous Mycobacterium fortuitum infection occurring in a 53-year-old man with multiple subcutaneous nodules on his right thigh and right lower leg. He has been treated with long-term systemic corticosteroids for his nephrotic syndrome. He had no constitutional symptoms and no lymphadenopathy. Laboratory findigs were within normal limits except for abnormal values for nephrotic syndrome. The skin biospy specimen showed a mixed pattern of epithelioid granuloma with micropseudocyst containing acid-fast bacilli. Methenamine silver stain was negative. The cultures from the skin biopsy specimens on Ogawa media(3% KH_2PO_4) at 24℃, 32℃, 37℃, yielded colonies of M. fortuitum after 4 days. Culture on Sabouraud media revealed no growth. DOPA reaction was negative. Nitrate reduction test was positive and Tween 80 hydrolysis test was negative. Urine and sputum cultures for atypical mycobacteria were negative. This M. fortuitum was sensitive to amikacin or tetracycline. Four months later, the skin lesions regressed without therapy.
전성진,서기석,김상태,허만하 고신대학교(의대) 고신대학교 의과대학 학술지 1990 고신대학교 의과대학 학술지 Vol.6 No.1
We report 2 cases of erythema elevatum diutinum, one in a 53-year-old woman(case 1) and the other in a 70-year-old woman(case 2). The patients had painful erythematous papules, plaques, bullae and nodules on the dorsa of both hands. ASLO value showed marked elevation in case 1. A test for recall antigen(Multitest CMI) showed positive reaction to streptococcal antigen(Lancefield group C) in case 2. Histopathologic findings showed dense perivascular infiltration of neutrophils, lymphoid cells and nuclear dusts with deposition of fibrinoid materials withiin and around the blood vessel walls. On administration of dapsone, her skin lesions improved remarkably in case 2.