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Association between PON1 Gene SNPs and Growth and Carcass Traits in Beef Cattle
Ji, A.G.,Huai, Y.H.,Zhou, Z.K.,Li, Y.J.,Zhang, L.P.,Xu, S.Z.,Gao, X.,Ren, H.Y.,Chen, J.B. Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.8
Paraoxonase-1 (PON1), like lipoprotein lipase (LPL), plays a key role in the metabolism and physiology of mammalian growth. The objectives of this study were to estimate the allele and genotype frequencies at the PON1/EcoRV and PON1/AluI loci in three genetic groups of beef cattle and to determine associations between these polymorphisms and growth and carcass traits. Genotyping was performed on 30 Angus, 32 Hereford and 26 Simmental. The association analysis was carried out using the GLM procedure of SAS 9.1 and the least squares means of the genotypes were compared by the Tukey's test. Animals with AG genotype at the PON1/EcoRV locus had higher weight at the time of entry into the fattening corrals ($329.97{\pm}6.08kg$) and close to the time of slaughter ($577.56{\pm}8.32kg$) and net meat weight ($275.89{\pm}4.05kg$) and fitted tenderness ($3.10{\pm}0.19kg$) (p<0.05). Animals with AA genotype at the PON1/AluI locus had higher weight at the time of entry ($333.37{\pm}8.93kg$) and slaughter ($576.82{\pm}13.18kg$) and net meat weight ($275.49{\pm}6.43kg$) and average daily gain ($0.68{\pm}0.02kg/d$) (p<0.05). The meat color score was also significantly higher (p<0.05). Between genotypes and breeds, there were significant differences observed except for TBW, REMG, MBS, REA and MCS. As a metabolism gene, genotypes of the SNPs of PON1 gene might be reflecting BFT directly, such as $A_eA_eG_aG_a$ genotype in this experiment.
R&D Status of High-current Accelerators at IFP
J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61
High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.
Amin, A.R.M.R.,Karpowicz, P.A.,Carey, T.E.,Arbiser, J.,Nahta, R.,Chen, Z.G.,Dong, J.T.,Kucuk, O.,Khan, G.N.,Huang, G.S.,Mi, S.,Lee, H.Y.,Reichrath, J.,Honoki, K.,Georgakilas, A.G.,Amedei, A.,Amin, A. Saunders Scientific Publications ; Academic Press 2015 SEMINARS IN CANCER BIOLOGY Vol.35 No.suppl
The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to continue to proliferate, cancer cells must somehow uncouple themselves from the many signals that exist to slow down cell growth. Here, we define the anti-growth signaling process, and review several important pathways involved in growth signaling: p53, phosphatase and tensin homolog (PTEN), retinoblastoma protein (Rb), Hippo, growth differentiation factor 15 (GDF15), AT-rich interactive domain 1A (ARID1A), Notch, insulin-like growth factor (IGF), and Kruppel-like factor 5 (KLF5) pathways. Aberrations in these processes in cancer cells involve mutations and thus the suppression of genes that prevent growth, as well as mutation and activation of genes involved in driving cell growth. Using these pathways as examples, we prioritize molecular targets that might be leveraged to promote anti-growth signaling in cancer cells. Interestingly, naturally occurring phytochemicals found in human diets (either singly or as mixtures) may promote anti-growth signaling, and do so without the potentially adverse effects associated with synthetic chemicals. We review examples of naturally occurring phytochemicals that may be applied to prevent cancer by antagonizing growth signaling, and propose one phytochemical for each pathway. These are: epigallocatechin-3-gallate (EGCG) for the Rb pathway, luteolin for p53, curcumin for PTEN, porphyrins for Hippo, genistein for GDF15, resveratrol for ARID1A, withaferin A for Notch and diguelin for the IGF1-receptor pathway. The coordination of anti-growth signaling and natural compound studies will provide insight into the future application of these compounds in the clinical setting.
Electrical Measurements of an AlGaN/GaN High-electron-mobility Transistor Structure Grown on Si
Zhi-Yao Zhang,Shun-Tsung Lo,Li-Hung Lin,Kuang Yao Chen,J. Z. Huang,Zhi-Hao Sun,C.-T. Liang,N. C. Chen,Chin-An Chang,P. H. Chang 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.9
We report on magnetotransport results for an Al<sub>0.15</sub>Ga<sub>0.85</sub>N/GaN high-electron-mobility-transistor structure grown on a p-type Si (111) substrate. Our results show that there exists an approximately temperature (<i>T</i>)-independent point, which could be ascribed to a direct transition from a weak insulator to a high Landau level filling factor quantum Hall state, exists in the longitudinal resistivity ρ<sub>xx</sub>. The Hall resistivity decreases with increasing <i>T</i>, compelling experimental evidence for electron-electron interaction effects in a weakly-disordered two-dimensional (2D) system. We find that electron-electron interaction effects can be estimated and eliminated, giving rise to a corrected nominally temperature-independent Hall slope. By fitting the low-field magnetotransport data to conventional 2D weak localization theory, we find that the dephasing rate 1/τ<sub>φ</sub> is proportional to <i>T</i>. Moreover, 1/τ<sub>φ</sub> is finite as <i>T</i> → 0, evidence for zero-temperature dephasing in our system.
Radiative decay of theψ(2S)into two pseudoscalar mesons
Bai, J. Z.,Ban, Y.,Bian, J. G.,Blum, I.,Chen, A. D.,Chen, G. P.,Chen, H. F.,Chen, H. S.,Chen, J.,Chen, J. C.,Chen, X. D.,Chen, Y.,Chen, Y. B.,Cheng, B. S.,Choi, J. B.,Cui, X. Z.,Ding, H. L.,Dong, L. Y American Physical Society 2003 Physical review. D, Particles and fields Vol.67 No.3
Evaluations of Neutron Data for T and ^3He with R-Matrix Method
W. L. Sun,Z. P. Chen,Y. F. Lin 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
New evaluations for n+T and n+^3He reactions are carried out by using our R-Matrix code RAC. The best R-Matrix parameters are obtained by fitting data of all necessary reactions simultaneously. The fitting for n+T reaction includes the available experimental data (E ≤ 40 MeV) from EXFOR database, corresponding to those of T(n,n)T, T(n,d)2n, ^3He(p,p)^3He, and ^3He(p,2p)D+^3He(p,2pn)p, while the fitting for n+^3He reaction uses the data of ^3He(n,n)^3He, ^3He(n,d)D, ^3He(n,p)T, ^3He(n,np)D+^3He(n,2np)^1H, ^3He(n,g)^4He, T(p,p)T, and T(p,n)^3He. Then, these best R-Matrix parameters are applied to calculate the cross sections and their corresponding covariance matrices. The present evaluations agree well with the experimental data, and are obviously better than those of ENDF/B-VII, CENDL-2.1, or JENDL-3.3, particularly the cross sections for T(n,d)2n and ^3He(n,np)D+^3He(n,2np)p reactions.
Lai, Y.-T.,Wang, M.-Z.,Adachi, I.,Aihara, H.,Asner, D. M.,Aulchenko, V.,Aushev, T.,Bakich, A. M.,Bala, A.,Bhuyan, B.,Bobrov, A.,Bozek, A.,Brač,ko, M.,Browder, T. E.,Chang, P.,Chekelian, V.,Chen, American Physical Society 2014 PHYSICAL REVIEW D - Vol.89 No.5
<P>We search for the charmless B-o decay with final state particles p (Lambda) over bar pi(-)gamma using the full data sample that contains 772 x 10(6)B (B) over bar pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. This decay is predicted to proceed predominantly via the b -> s gamma radiative penguin process with a high energy photon. No significant signal is found. We set an upper limit of 6.5 x 10(-7) for the branching fraction of B-o -> p (Lambda) over bar pi(-)gamma at the 90% confidence level.</P>
Zhao, K.J.,Nagashima, Y.,Li, F.M.,Shi, Yuejiang,Diamond, P.H.,Dong, J.Q.,Itoh, K.,Itoh, S.-I.,Zhuang, G.,Liu, H.,Chen, Z.P.,Cheng, J.,Nie, L.,Ding, Y.H.,Hu, Q.M.,Chen, Z.Y.,Rao, B.,Cheng, Z.F.,Gao, L. IOP 2017 Nuclear fusion Vol.57 No.12
<P>The temporal-spatial structures of plasma flows and turbulence around tearing mode islands are presented. The experiments were performed using Langmuir probe arrays in the edge plasmas of J-TEXT tokamak. The correlation analyses clearly show that the flows have similar structures of <I>m</I>/<I>n</I> = 3/1 as the magnetic island does (<I>m</I> and <I>n</I> are the poloidal and toroidal mode numbers, respectively). The sign of the potential fluctuations for the flows inverses and the powers significantly reduce at <I>q</I> = 3 surface. Approaching to the last closed flux surface for the magnetic islands, the radially elongated flow structure forms. The flows are concentrated near separatrix and show quadrupole structures. The turbulence is concentrated near X-point and partly trapped inside the magnetic islands.</P>
P. Z. Si,X. L. Wang,X. F. Xiao,H. J. Chen,X. Y. Liu,L. Jiang,J. J. Liu,Z. W. Jiao,H. L. Ge 한국자기학회 2015 Journal of Magnetics Vol.20 No.3
Cr₂O₃ nanoparticles were prepared via one-step reactive laser ablation of Cr in oxygen. The metastable CrO₂ phase was obtained through the subsequent oxidation of Cr₂O₃ nanoparticles under O₂ with gas pressures of up to 40 MPa. The as-prepared Cr₂O₃ nanoparticles are spherical or rectangular in shape with sizes ranging from 20 nm to 50 nm. High oxygen pressure annealing is effective in producing meta-stable CrO₂ from as-dried Cr₂O₃ nanoparticles, and the Cr₂O₃ nanoparticles exhibit a weak ferromagnetic behavior with an exchange bias of up to 11 mT that can be ascribed to the interfacial exchange coupling between uncompensated surface spins and the antiferromagnetic core. The Cr₂O₃/CrO₂ nanoparticles exhibit an enhanced saturation magnetization and a reduced exchange bias with an increasing faction of CrO₂ due to the elimination of uncompensated surface spins over the Cr₂O₃ nanoparticles when exposed to a high pressure of O₂ and/or possible phase segregation that results in a smaller grain size for both Cr₂O₃ and CrO₂.