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Xia, L.,Idhayadhulla, A.,Lee, Y.R.,Kim, S.H.,Wee, Y.J. Korean Society of Industrial and Engineering Chemi 2015 Journal of industrial and engineering chemistry Vol.22 No.-
Diverse 3,5,6,7-tetrahydrobenzofuran-4-one derivatives (3a-3n) were synthesized in high yields by ruthenium complex or rhodium complex catalyzed [3+2] cycloaddition. The antibacterial activities of these 3,5,6,7-tetrahydrobenzofuran-4-ones were evaluated against Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter aerogenes) and Gram-positive bacteria (Bacillus cereus and Staphylococcus aureus). In particular, compound 3b showed the highest antibacterial activity against P. aeruginosa and S. aureus (both MICs: 2μg/mL). Compound 3l, which has the 2H-pyrano[2,3-b]benzofuran skeleton, exhibited excellent inhibitory activity against B. cereus (MIC: 0.5μg/mL) as compared with ciprofloxacin (MIC: 2μg/mL) and ampicillin (MIC: 1μg/mL).
Jaeger, S.R.,Kim, K.O.,Lee, S.M.,Hunter, D.C.,Kam, K.,Chheang, S.L.,Jin, D.,Lee, P.Y.,Xia, Y.,Ares, G. Longman Scientific Technical ; Elsevier Science Pu 2017 Food quality and preference Vol.56 No.1
<P>In line with research in non-Western countries becoming main-stream, the need to validate existing research methods with consumers from these populations increase. The present research contributes hereto by quasi-replicating with Korean and Chinese consumers previous research concerning the risk of hedonic product responses being biased by co-elicitation of CATA/RATA questions for sensory product characterisation. Using consumers in several Western countries it was previously reported that bias could occur, but was unlikely to. Eleven studies involving 1000 East Asian consumers confirmed this conclusion. The studies were conducted with diversified populations and across multiple product categories. Across 7 studies, there were no instances where CATA co-elicitation was found to bias hedonic scores. However, in one of four studies where RATA responses were co-elicited bias did occur, and hedonic scores were, on average, lower when RATA responses were co-elicited. It is recommended that the research be replicated with consumers residing in their home countries and extended to other East and South-East Asian counties. (C) 2016 Elsevier Ltd. All rights reserved.</P>
R&D Status of High-current Accelerators at IFP
J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61
High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.
Effects of Copper-bearing Montmorillonite (Cu-MMT) on Escherichia coli and Diarrhea on Weanling Pigs
Xia, M.S.,Hu, C.H.,Xu, Z.R.,Ye, Y.,Zhou, Y.H.,Xiong, L. Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.12
Copper-bearing montmorillonite (Cu-MMT) was produced by $Cu^{2+}$ cation exchange reaction. X-ray diffraction analysis showed that that the (001) basal spacing of the MMT crystal lattice increased from 1.544 to 1.588 nm after $Cu^{2+}$ exchange. This indicated that $Cu^{2+}$ entered into interlayer position of MMT as a hydrated cation or composite cation. In vitro results indicated that Cu-MMT had antibacterial activity on Escherichia coli $K_{88}$. Cu-MMT had unbalanced positive charge after cation exchange. Its antibacterial activity resulted from two aspects, one was electrostatic attraction which made E. coli $K_{88}$ being adhered on the montmorillonite surface, the other was the $Cu^{2+}$ slowly released, which could kill bacteria. In an in vivo study, four replicates of eight weanling pigs were assigned to each of two dietary treatments to study the effects of Cu-MMT on diarrhea, E. coli in the lumen of the jejunum and morphology of jejunal mucosa. As compared to the control, supplementation of the diet with 0.2% Cu-MMT improved average daily gain by 12.50% (p<0.05) and decreased F/G by 9.42% (p<0.05). The mean diarrhrea incidence was decreased by 71.80% (p<0.05). The viable counts of Escherichia coli in jejunal contents were significantly reduced (p<0.05). Villus height and the villus height to crypt depth ratio at the jejunal mucosa were increased by 19.09% (p<0.05) and 37.10% (p<0.05), respectively.
Yun, S.H.,Xia, L.,Edison, T.N.J.I.,Pandurangan, M.,Kim, D.H.,Kim, S.H.,Lee, Y.R. Elsevier Sequoia 2017 Sensors and actuators. B Chemical Vol.240 No.-
A novel ethylenediamine (EDA) based chemosensor 5 [dimethyl 2,2'-((3-oxocyclohex-1-ene-1,2-diyl)bis(azanediyl))dibenzoate] has been designed and synthesized for the turn on fluorescence sensing of Cu<SUP>2+</SUP> ions. The molecular geometry configuration of 5 is identified by X-ray diffraction and its corresponding orbital electron distributions are predicted by density functional theory (DFT). The probe 5 exhibits strong and selective complexing ability towards Cu<SUP>2+</SUP> over the other metal ions tested in both acetonitrile and aqueous solvent systems. MeCN-HEPES buffer system is more suitable for the selective fluorescence sensing of Cu<SUP>2+</SUP> ions. In addition, the lowest detection limit is 0.30μM for Cu<SUP>2+</SUP> ions. This probe has also been applied successfully for the confocal fluorescence imaging of MDCK cells. Therefore, this probe can be used in both the environmental and biological systems for the detection of Cu<SUP>2+</SUP>.
Field Measurements of the New CCTV Tower in Beijing
Xu, Y.L.,Zhan, S.,Xia, H.,Xia, Y.,Zhang, N. Council on Tall Building and Urban Habitat Korea 2013 International journal of high-rise buildings Vol.2 No.3
The emergence of a growing number of tall buildings, often with unusual shapes and innovative structural systems, has led to the realization of the need for and the importance of field measurements. The new China Central Television (CCTV) Tower in Beijing is one of tall buildings with a highly unusual shape and a complex structural system, requiring field measurements to identify its dynamic characteristics for the subsequent dynamic analysis of the tower under wind excitation, seismic-induced ground motion and traffic-induced ground motion. The structural system and the finite element model of the CCTV Tower are first introduced in this paper. The computed natural frequencies and mode shapes are then presented as a reference for the field measurement. After introducing the arrangement of the ambient vibration measurement, the field measured natural frequencies and damping ratios of the CCTV Tower are presented and the measured natural frequencies are finally compared with the computed ones. It was found that the structural damping ratios of the CCTV Tower are small and the computed natural frequencies are smaller than the measured ones by about 12~17%.
Synthesis of novel and diverse mollugin analogues and their antibacterial and antioxidant activities
Idhayadhulla, A.,Xia, L.,Lee, Y.R.,Kim, S.H.,Wee, Y.J.,Lee, C.S. Academic Press ; Academic Press 2014 Bioorganic chemistry Vol.52 No.-
Novel and diverse mollugin analogues (1-12) were synthesized using PhB(OH)<SUB>2</SUB>/AcOH-mediated electrocyclization reaction as a key step. The newly synthesized compounds were screened for antioxidant and antibacterial activities. Compounds 1, 2, 5, 6, 8, and 10-12 showed high antioxidant activities in DPPH inhibition (IC<SUB>50</SUB>=0.52-1.11μM) compared with BHT (IC<SUB>50</SUB>=9.67μM). Compounds 3 exhibited potent antibacterial activity against Staphylococcus aureus (KCTC-1916) bacterial strain at 100μg/mL. Structures of newly synthesized compounds were confirmed by IR, <SUP>1</SUP>H NMR, <SUP>13</SUP>C NMR data and high-resolution mass spectrometry.