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      • 유니섹스모드 수용도와 성격 특성과의 관계 연구

        김영숙,박은영,이영선,허영미,홍은영 효성여자대학교 가정대학 학도호국단 1985 家政大論集 Vol.4 No.-

        The purposes of this study were 1) to investigate the relationship between theacceptance oF unisex mode and rigidity character and 2) to find out any significantdifference in the acceptance of unisex mode according to grade, major and sex. The questionnaires were administered to 133 female and 174 male college students. The results; 1. The accptance of unisex mode was not related with rigidity character. 2. The acceptance of female unisex mode was higher than male unisex mode. 3. Females showed higher tendency in the acceptance of unisex mode and fashioninnovativeness than males. 4. No significant differences were found in the acceptance of unisex mode accordingto grade and major level.

      • HMG-CoA 환원효소 억제제에 의한 ICAM-1 유전자의 발현조절

        김현진,정효균,홍우정,김군순,조영석,김도희,채수흥,구본정,송민호,노흥규,김영건 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

        Background : ICAM-1 act as one of major adhesion molecules in the atherosclerotic lesion. ICAM-1 expression is mainly regulated at the level of transcription and depend on IFN-γ signal transduction pathway in which the STAT1 transcrption factor is a critical intermediate. IFN-γreceptor not only initiates tyrosine 701 phosphorylation of STAT1 by Jak1 and Jak2, but also phosphorylates serine 727 through the activation of Raf-1/MAP kinases. HMG-CoA reductase inhibitors have anti-atherosclertic effects, beyond normalization of hypercholesterolemia, by directly acting on endothelial cells, macrophages and vascular smooth muscle cells. HMG-CoA reductase inhibitors suppress the synthesis of isoprenoid intermediates such as geranylgeranyl-pyrophosphate or farnesylpyrophosphate. These effects results inhibitors suppress the synthesis of isoprenoid intermediates such as geranylgeranyl-pyrophosphate or farnesylpyrophosphate. These effects results inhibition posttranslational farnesylation and geranyl-geranylation processing of small GTP-binding preoteins and inhibition of normal signaling activities. Method : We made several 5'-deletion constructs of rat ICAM-1 promoter and analyzed the promoter activities by measuring the luciferase activity after transfection into ECV304 cells and smooth muscle cells. We checked the level of total and phosphorylated STAT1 protein by immunoblot analysis using specific antibodies. Results : Lovastatin inhibits IFN-γ-induced ICAM-1 gene expression in the ECV304cell. The cells pretreated with PD98059, MEKK inhibitor showed significantly low ICAM-1 RNA induction with IFN-γ stimulatio. IFN-γ induced phosphorylation of tyrosine 701 was not significantly changed by the pretreatment of lovastatin. But lovastatin suppresses IFN-γ-induced phosphorylation of ERK1/ERK2 which are responsible for the seine 727 phosphorylation in STAT1. Conclusion : We showed that HMG-CoA reductase inhibitors, lovastatin, suppresses IFN-γ mediated ICAM-1 gene expression through the inhibition of transcription. HMG-CoA reductase inhibitor suppresses IFN-γ-induced phosphorylation of serine 727 in STAT1 through the modulation of MAP kinases.

      • 전문대학 간호과 통합교과과정 개발에 관한 연구

        김영희,김정수,김정애,방숙명,배경진,이애경,장은정,정안순,주미경,최나영 경복대학 1998 京福論叢 Vol.2 No.-

        교과과정의 조직은 체계적이고 뜻이 있는 순서로 학생들을 가르치기 위해 지식을 어떻게 조직화할 것인지와, 과목들 사이에서 공통된 내용은 통합시켜 중첩되는 일이 없도록 조정할 필요가 있다. 이에 현재 본 대학 간호과에서 운영되었던 97학년도의 17개 전공과목들의 교과과정의 내용을 비교, 분석하여 중복을 줄이며 순차적 지식의 습득을 도모하는 새로운 통합교과과정의 틀을 개발, 제시함으로써 보다 나은 전문직 간호교육이 이루어지도록 하고자 하였다. Most curricula are considered how to teach the student in systematic and meaningful orders. And it is necessary to coordinate the duplicate contents in major subjects in nursing. So this study was designed to set up a new comprehensive curriculum through comparing and ananlyzing each seventeen major subjects in Nursing Department of Kyung-Bok College. Therefore, the purpose of this study is to present the new comprehensive curricula for promoting the efficiency and effectiveness in diploma degree course of nursing education.

      • SCISCIESCOPUS

        Characterization of the isotropic-distortional hardening model and its application to commercially pure titanium sheets

        Pham, Quoc Tuan,Lee, Myoung Gyu,Kim, Young Suk Pergamon Press 2019 International journal of mechanical sciences Vol.160 No.-

        <P><B>Abstract</B></P> <P>Commercially pure titanium sheets have been widely used in various industrial applications owing to their lightweight nature, superior formability, and excellent corrosion resistance. Previous studies showed that accurate modelling of material characteristics, such as anisotropic yield function and hardening, is essential for the simulation of sheet metal forming with titanium sheets. For example, the non-quadratic anisotropic yield function Yld2000-2d and the modified Kim–Tuan hardening model were used to model initial anisotropy and reproduce flow stress curves at large strains. However, even with these advanced constitutive models for describing the anisotropic behavior of sheet metals, further improvement is necessary to simulate anisotropy evolution, or distortional hardening, in pure titanium sheets. In this study, distortional hardening was experimentally measured under both uniaxial and balanced biaxial loading conditions. Moreover, the evolution of the Yld2000-2d function was modelled as a function of equivalent plastic work. For validation, the developed material models were applied in finite element simulations to analyse deformation behavior in uniaxial tension, hydraulic bulge, and punch-stretching tests. It was confirmed that this approach accurately described material response during these three tests.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Experimental observation of distortional hardening behaviour and three-stage deformation behavior for a pure titanium sheet. </LI> <LI> A procedure to reproduce these material behaviours for the tested material by using an evolutionary yld2000-2d yield function and modified Kim–Tuan hardening law. </LI> <LI> Simulation results of uniaxial tensile tests, hydraulic bulge test, and punch-stretching tests match well with experimental data. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • SCOPUSKCI등재

        New Stress-Strain Model for Identifying Plastic Deformation Behavior of Sheet Materials

        김영석(Young Suk Kim),팜콕트완(Quoc Tuan Pham),김찬일(Chan Il Kim) Korean Society for Precision Engineering 2017 한국정밀공학회지 Vol.34 No.4

        In sheet metal forming numerical analysis, the strain hardening equation has a significant effect on calculation results, especially in the field of spring-back. This study introduces the Kim-Tuan strain hardening model. This model represents sheet material behavior over the entire strain hardening range. The proposed model is compared to other well known strain hardening models using a series of uniaxial tensile tests. These tests are performed to determine the stress-strain relationship for Al6016-T4, DP980, and CP Ti sheets. In addition, the Kim-Tuan model is used to integrate the CP Ti sheet strain hardening equation in ABAQUS analysis to predict spring-back amount in a bending test. These tests highlight the improved accuracy of the proposed equation in the numerical field. Bending tests to evaluate prediction accuracy are also performed and compared with numerical analysis results.

      • KCI등재

        신경회로망에 의한 용접 결함 종류의 정량적인 자동인식 시스템 개발에 관한 연구

        김재열,김영석,김병현,유신,김훈조,정진홍 한국공작기계학회 1997 한국생산제조학회지 Vol.6 No.1

        A neural network approach has been developed to determine the depth of a surface breaking crack in a steel plate from ultrasonic backscattering data. The network is trained by the use of feedforward three-layered network together with a back-scattering algorithm for error correction. The signal used for crack insonification is a mode converted 70˚ transverse wave. A numerical analysis of back scattered field is carried out based on elastic wave theory, by the use of the boundary element method. The numerical data are calibrated by comparison with experimental data. The numerical analysis provides synthetic data for the training of the network. The training data have been calculated for cracks with specified increments of the crack depth. The performance of the network has been tested on other synthetic data and experimental data which are different form the training data.

      • 양성 갑상선 결절에서의 무수 알코올 치료 효과

        김도희,나소영,이효진,홍우정,김군순,조영석,구본정,송민호,김영건,노흥규 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        목적 : 양성 갑상선 결절 환자에서의 PEI의 치료효과 및 부작용을 알아보고자 하였다. 방법 : 양성 갑상선 결절 환자 88명을 대상으로 초음파 소견에 따라 낭종성 결절, 복합성 결절, 고형성 결절 등 세 그룹으로 분류후 전체 및 각각에 대한 PEI의 치료효과 및 부작용을 조사하였다. 결과 : 양성 갑상선 결절 환자 88명을 PEI로 치료후 결절의 크기가 50%이상 감소한 경우는 전체 환자중 77.2%이었고 각 결절별로 살펴보면 고형성 결절에서 52.6%, 복합성 결절에서 72.4%, 낭종성 결절은 92.5%이었다. 부작용은 동통, 결절내 출혈, 감염, 결절의 누출등이 있었으나 대부분 무증상이었다. 결론 : PEI는 양성 갑상선 결절 환자증 적응증을 잘 살펴 고려해 볼 수 있는 치료법이라 생각되며 특히 낭종성 결절 환자에서 주사기에 의한 흡인후에 재발한 경우 일차적인 치료로 PEI를 고려해 볼 수 있겠다. Ultrasonography(US)-guided percutaneous ethanol injection (PEI) has been performed for the treatment of autonomous functioning thyroid nodules, thyroid cysts, & cold thyroid nodules. The author studied the efficacy of PEI in the treatment of benign cold thyroid nodules both solid and cystic (complex & pure). Eighty-eight euthyroid outpatients (age:44.2±13.9years, 75 women and 13 men) with benign cold thyroid nodules or simple thyroid cysts (69 with a single nodule and 19 with a prominent nodule within multinodular goiter) were includied in this study. After PEI, each subtype of thyroid nodules was divided into three groups in according to volume reduction complete response (90% or more of volume reduction), partial response (50% or more of reducton but below 90%), and failure (below 50% or increase in size) group. Overall response rates of PEI for benign thyroid nodules were complete 45(51.1%), partial 23(26.1%), failure 20(22.7%). In 20 cold solid nodules, complete response was observed in 6(30.0%), partial response in 5(25.0%), and failure in 9(45.0%). In 28 complex cysts, complete response was observed in 8(28.6%), partial response in 12 (42.9%), and failure in 8(28.6%). In 40 pure cysts, complete response was observed in 31(77.5%), partial response in 6 (15.0%), and failure in 3 (7.5%). Side effects comprised pain 8 (9.2%), intranodular bleeding 13 (14.6%), extracapsular leakage 1(1.1%), infection 1 (1.1%), increased size l(1.1%), and none 64(72.7%). PEI may prove a safe & effective tool for the therapy of cold thyroid nodules in selected cases and may be the treatment of choice of recurrent thyroid cysts. However, further investigation involving a larger number of patients and a longer follow-up is needed.

      • 數種의 市販 淸凉飮料에 依한 琺瑯質 脫灰效果

        김영숙,신영림,송근배,김영진 慶北大學校 齒科大學 1992 慶北齒大論文集 Vol.9 No.1

        The purpose of this study was to investigate the effects of tooth enamel dissolution by commercial beverages. Five kinds of beverages(cola, cider, aquarius, boribori and sunkist orange) were selected for test medium and sixteen of extracted 3rd molar were used for tooth enamel specimens. The acidity of each beverage was determined with pH meter and the concentration of total glucose was checked with Glucose kit and U-V spectrophotometer. The dissolved calcium was determined by Atomic Absoprtion Spectrophotometer and the change of enamel surfaces were observed with Scanning Electron Microscopy(× 400 & × 1,000 magnification). All collected data were analyzed by one-way & two-way ANOVA in SPSS/PC^+ program. The obtained results were as follows: 1. The major containing acid type of cola beverage was phosphoric acid but the other beverages(cider, aquarius, boribori and sunkist) were citric acid. The pH of each beverage was lowest in cola and sport drink, cider, boribori, fruit juice in ascending order(F=205.85, p<0.001), the average pH of 5 kinds of beverage was 2.84 ±0.04, all beverages used in this experiment were low enough to decalcify the tooth enamel. The total glucose concentration of each beverage was 2.74% in aquarius, 2.78% in cider, 3.96% in sunkist, 4.23% in boribori and 4.27% in cola. 2. The average dissolved calcium concentration in 5cc of beverage was 1.54±0.12ppm/5㎖ of HNO_3 in cola, 1.76±0.38ppm in sunkist, 1.90±0.09ppm in boribori, 3.03±0.09ppm in aquarius, 3.59±0.38ppm in cider and the final calcium contents, which is extrated original calcium contents from total calcium contents after 120 minutes were highest in cola(1.27ppm) and aquarius(1.02ppm), cider(0.58ppm), sunkist(0.45ppm), boribori(0.33ppm) in the order(p<0.05). 3. The direct proportional relationship was not found between the degree of surface change on Scanning Electron Microscopy and the amount of dissolved calcium per immersion time. But the more the immerging time was lengthened, the more surface change was observed. The surface change of 120 minutes group was more remarkable than 30 and 60 minutes immerged group in each beverage.

      • Temperature Dependence of Delayed Hydride Cracking Crack Velocity in Zr-2.5Nb Tubes

        Young Suk Kim(김영석) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.11

        Delayed hydride crack tests were conducted on Zr-2.5Nb tubes with different distributions of the β-Zr at temperatures ranging from 125 to 300 ℃. Compact tension specimens charged to 27 to 100 ppm hydrogen were used to determine temperature dependences of their DHC velocity (DHCV) and striation spacing. The Zr-2.5Nb tube with a higher yield strength and a seimi-continuous β-Zr has a higher DHCV and a smaller striation spacing than that with a fully discontinuous β-Zr and a lower yield strength. It is found that the activation energy for the DHCV is the sum of the activation energy for hydrogen diffusion and the striation spacing representing the hydrogen concentration gradient at the crack tip. Quantitative contribution of hydrogen diffusion nad the hydrogen concentration gradient to the DHCV is discussed. This study provides supportive evidence to the feasibility of Kim’s DHC model.

      • SCISCIESCOPUS

        Delayed Hydride Crack Velocity of Zirconium Alloys with the Direction of an Approach to Temperature

        KIM, Young Suk,KIM, Kang Soo,CHEONG, Yong Moo Atomic Energy Society of Japan 2006 Journal of nuclear science and technology Vol.43 No.9

        <P>The delayed hydride cracking (DHC) tests were conducted on Zr-2.5Nb compact tension specimens with the test temperatures reached by a heating and a cooling. The Zr-2.5Nb specimens were either furnace-cooled or water-quenched after a hydrogen charging treatment to contain 10 to 100 ppm H. On an approach to the test temperatures by a cooling, both the Zr-2.5Nb specimens showed the DHC velocity increasing with an increasing temperature over a temperature range of 100–300°C, irrespective of the cooling rate. However, on an approach to the test temperatures by heating, the furnace-cooled Zr-2.5Nb showed a DHC arrest at temperatures over 180°C and no DHC at 250°C, and the water-quenched ones did have a DHC growth, even at 250°C. Using Kim’s DHC model we elucidate the DHC arrest in the furnace-cooled Zr-2.5Nb at temperatures over 180°C and the DHC growth in the water-quenched specimen, even at 250°C, upon an approach by a heating.</P>

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