Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression

Lee, Jeong-Min,Jang, Young-Saeng,Jin, Bo-Ra,Kim, Sun-Jin,Kim, Hyeon-Jin,Kwon, Bo-Eun,Ko, Hyun-Jeong,Yoon, Sung-il,Lee, Geun-Shik,Kim, Woan-Sub,Seo, Goo-Young,Kim, Pyeung-Hyeun CHINESE SOCIETY OF IMMUNOLOGY 2016 CELLULAR AND MOLECULAR IMMUNOLOGY Vol.13 No.6

<P>Lactoferrin (LF) and retinoic acid (RA) are enriched in colostrum, milk, and mucosal tissues. We recently showed that LF-induced IgA class switching through binding to betaglycan (transforming growth factor-beta receptor III, T beta RIII) and activation of canonical TGF-beta signaling. We investigated the combined effect of LF and RA on the overall IgA response. An increase in IgA production by LF was further augmented by RA. This combination effect was also evident in Ig germ-line alpha (GL alpha) transcription and GLa promoter activity, indicating that LF in cooperation with RA increased IgA isotype switching. We subsequently found that RA enhanced T beta RIII expression and that this increase contributed to LF-stimulated IgA production. In addition to the IgA response, LF and RA in combination also enhanced the expression of the gut-homing molecules C-C chemokine receptor 9 (CCR9) and alpha 4 beta 7 on B cells. Finally, peroral administration of LF and RA enhanced the frequency of CCR9(+)IgA(+) plasma cells in the lamina propria. Taken together, these results suggest that LF in cooperation with RA can contribute to the establishment of gut IgA responses.</P>

동천의 정화능력 평가

라덕관,박상숙,김기성,김영규,김성진 순천대학교 1999 순천대학교 자연과학논문집 Vol.18 No.2

This study was carried out to investigate the self-purification capacity of Dongcheon in Sunchon. According to water quality of Dongcheon, the mean concentrations of BOD and DO were 0.7∼1.6㎎/ℓ and 7.1∼8.0㎎/ℓ, which correspond to the grade Ⅱ of water quality standards. The ratio of BOD loading inflowed from Sunchon-city, Seocheon and Okchoen were measured 4.8%, 52.1% and 23.7%, respectively. The deoxygenation constant(k_1) and reaeration constant(k_2) of Dongchoen were estimated as 3.19day^(-1) and 2.181day^(-1). The results of DO distribution analysis by Streeter-Phelps equation showed that critical point was 12.1㎞ downstream, and then DO concentration was 6.94㎎/ℓ. In addition, the self-purification capacity assessment indicated that BOD loading to maintain over 5㎎/ℓ of DO should be less than 0.925ton/day.

點郡 3㎖(H) 의 振動寫眞 및 Weissenberg寫眞에서의 特性

이진호,류보영,조소라,김문집,추금홍,서일환,임성수 순천향대학교 1993 논문집 Vol.16 No.3

Crtstallographic cell constants of point group ?? are a =b≠c, α=β=90。, and γ=120。. There are mirror plane symmetries in oscillation photography taken at a-axis and b-axis, but no plane symmetry at c-axis. Since Weissenberg zeroth layer taken at a- and b-axis obeys Friend's law, half of the photography shows non-symmetric unit of diffraction intensity. There are 6 mirror planes in the Weissenberg zeroth layer when the photography was taken at c-axis, therefore 1/12 of the unit cell is non-symmetric unit.

Weissenberg 寫眞 技法에 의한 酸化마그네슘(MgO)의 結晶構造

이진호,류보영,조소라,김문집,추금홍,서일환,임성수 순천향대학교 1993 논문집 Vol.16 No.3

The structure of MgO crystal is faced centered cubic(FCC) with cell parameters of a=b=c=4.21Å, α=β=γ=90。. The ionic bond length between Mg and O atoms is 2.1Å. This crystal belongs to m3m point group and to Fm3m space group.

테니스 포핸드시 밀어치기와 때려치기 타법의 운동학적 분석

윤양진,정미라,서국웅,이훈식,황명숙,강영택,윤길환 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

This study consists in clarifying the meaning of various angles and velocity, and two types of the stroke of a pushing shot and hitting shot through the three-dimensional image analyses among the factors of exercise. To attain the purpose of such studies, the result of experiment and analysis for each of three athletes of boys and girls in high school and three persons in general came to the conclusion as follows; 1. The last motion of a group of A having a command of a follow shot showed greatly, compared with two groups of B and C, and this showed that a group of A took a rectilinear motion greatly to gain power and two group of B and C took a rotary motion greatly to gain speed. 2. A group of A having a command of a pushing shot move body weight forward from behind and give the first consideration to a rectilinear motion, and two groups of B and C having a command of the stroke of hitting shot used the turning of the shoulder and the waist and gave much weight to a rotary motion than a rectilinear one. 3. The position of the hitting point of a group of A having a command of a pushing shot turned out to be the waist, and that of the hitting point of two groups of B and C, the chest, and namely this showed that the position of the hitting point was decided according to the form of the stroke and pictures of various kinds. 4. In impacting, the speed decreased, for the power was controled to keep an accurate timing of stroke just before impacting

Web3D의 정보전달 방법에 관한 연구 : Web3D를 이용한 전자상거래에서 정보전달방법을 중심으로

박세라,이동윤,이진영 동서대학교부설연구센터 2001 연구센터논문집 Vol.4 No.1

As the development of the computing technology and the expansion of networking, the way of transmitting information has been changed from two dimension to three dimension. Specially, it has been changes rapidly on the internet. In two dimensional environment uses simply get texts and 2D images, but now we can get information dynamically and really through three dimensional environment. The paper shows the definition and features of Web3D representing 3D technology on the web. We also discuss about E-Commerce on Web3D and actually test the feature of Web3D.

임팩트시 테니스 라켓 재질의 차이에 따른 근전도 분석

윤양진,유국종,서국웅,정미라,강영택,이훈식,서국은 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

The purpose of this paper is to select 7 male athletes and female athletes of high school, and to compare their active potential differences of upper arm muscles according to characteristic of a racket. the results obtained are as follows: 1. According to the accumulative distribution rate of racket material, graphite and wood material show better efficiency in case of brachio radialis muscle of male athletes, but the racket material shows no constant efficiency in brachii radialis muscle of female athletes. In case of flexor carpi radialis muscle, wood material provides better efficiency only for male athletes. In case of triceps brachii muscle, wood material gives better efficiency to males athletes and steel material gives better efficiency to females athletes. Especially in case of biceps brachii muscle, neither male nor female athletes are influenced by racket materials at impact. 2. In the muscle load rate according to racket material, wood has the highest muscle active potential and graphite has the lowest active potential. Therefore, graphite is thoght to be better in the efficiency of muscle load rate.

소아의 악골내 발생한 낭종의 외과적 처치

김재곤,김영진,김미라,백병주 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.1

악골의 낭종은 크게 치성과 비치성으로 구분되며 치성낭은 치성기관이나 그 잔존 세포성분과 관련되어 주로 골내에서 발생한다. 비치성낭종은 과거에는 태아의 발육중 상피의 봉입이나 융합선을 따라 존재하는 상피잔사가 증식하여 낭성변형을 일으킨다는 설이 유력하였으나 현재에는 이러한 태아의 발육 동안 상피의 봉입은 일어나지 않는 것으로 보고 있다. 함치성낭은 미맹출 치아와 관련되어 발생하고 상피의 전암 가능성이 있으므로 가능한 빨리 제거하도록 하며 조대술이나 적출술이 이용될 수 있고 간혹 원인치의 발거가 추천된다. 비구개낭은 가장 일반적인 비치성낭으로 상악 중절치 사이에 경계가 명확한 방사선 투과상으로 나타난다. 적출술과 조대술로 치료할 수 있으며 전암 가능성이나 재발은 드물다. 본 증례에서는 전북대학교 병원 소아치과에 내원한 아동의 악골내 발생한 낭종을 외과적으로 제거한 후 다음과 같은 결론을 얻었다. 1.함치성낭의 환아에서, 원인 치아를 보존하고 완전 적출술로 병소를 제거한 후 경과를 관찰한 바 영구치의 정상적인 맹출이 이루어졌다. 2.비구개낭을 치료시, 인접치아의 생활력에 대한 정확한 진단과 그에 따른 치료법의 선택으로 불필요한 근관치료를 피할 수 있다. 3.향후 비구개낭의 환아의 관련치에 대한 계속적인 관찰이 필요하리 사료된다. 4.악골내 방사선 투과성의 병소를 치료시, 정확한 감별진단과 적절한 치료법의 선택이 중요하다. The Dentigerous cyst is reported to be one of the most common lesions of the jaw. It is derived from reduced enamel epithelium that surrounds the crown of an unerupted tooth. Dentigerous cysts usually remains asymptomatic and presents as well-circumscribed radiolucencies surrounding the crown of a tooth. Most dentigerous cysts are treated by surgical enucleation or marsupialization of the cyst to allow eruption of the permanent tooth. The nasopalatine duct cysts derived trom the islands epithelium remaining after closure of the embryonic nasopalatine duct. The cyst presents as a well-circumscribed oval or heart-shaped radiolucency located in the midline of the anterior maxilla between the roots of the central incisors. Treatments is by surgical enycleation, employing a paltal approach. This report present two cases. One case was diagnosed with dentigerous cyst and treated by enucleation. 12Months later, affected second premolar was erupted normally. The other case was diagnosed with nasopalation duct cyst. Histological examination of the enucleated cyst confirmed a nasopalatine duct cyst. There was no recurrence during follow up period.

점액낭종의 외과적 처치

김재곤,김영진,김미라,백병주 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

점액낭종은 타액선의 분비도관이 외상, 타석, 반흔조직등에 의해 폐쇄되거나 파열되어 점액이 조직내로 유출 및 저류되어 발생하는 가성의 낭종으로, 이 중 하마종은 구강저에서 발생하는 점액낭종에 사용하는 용어이다. 염증에 이환되지 않았다면 대부분이 무통의 양상을 나타내며 심부에 위치할수록 정상색조를 띄게된다. 점액낭종의 치료는 주로 재발을 방지하기 위하여 인접소타액선을 포함한 완전절제를 시행하며, 병소의 크기가 큰 경우 부분절제를 시행하기도 한다. 하마종의 치료는 조대술과 완전절제술이 있으며, 조대술은 잦은 재발을 일으키는 단점이 있으나 치료가 성공적으로 시행되었을 경우, 환자에게 타액선이 제거되는 불편감을 덜 할 수 있다. 본 증례에서는 하순과 구강저에 발생한 점액낭종과 하마종을 완전절제술과 조대술로 치료하고 그 경과를 관찰한 바 술 후 재발이 관찰되지 않았고, 정상기능을 회복하였다. 향후 치료부위의 재발여부에 대한 계속적인 관찰이 필요하리라 생각되며, 하마종의 치료시 조대술이 적절히 이용되었을 때 환아의 불필요한 타액선 절제를 피할 수 있다고 사료된다. 또한 점액낭종의 치료시, 병력과 임상적 특징을 바탕으로 한 정확한 감별진단과 적절한 치료법의 선택이 중요하다는 결론을 얻었다 주요어 : 점액낭종, 하마종, 조대술, 완전절제술

중량물 운반시 잡기유형에 따른 근전도 분석

이훈식,강영택,윤양진,정미라,유국종,서국웅,김정태 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

The purpose of this study was to examine EMG changes of the body according to method the holding during carrying object. The experiments were conducted with utilizing EMG analyses for five male and five female adults as subjects. The results were as followed. 1. The higher muscle action potential of vertical holding was shown than that of right holding when carrying objects in MMH work in proportion to the weight of the object. The came from the subjects using their brachial muscles much to maintain the angles of their wrist joints and elbow joints for keeping their stable postures while walking. 2. The higher muscle action potential of right holding was shown in right and left elector-muscles of their spines(L1-L2, L4-L5) while carrying in all stages of weights except 25kg objects than that of vertical holding. These results were caused from more use of brachial muscles than elector-muscles of spines in carrying weight objects. So vertical holding is more effective in carrying weight objects at a short distance than right holding.