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      • COMMUNITY PARTICIPATION IN AND BENEFITS OF TOURISM DEVELOPMENT IN THE TURPAN VALLEY, XINJIANG AUTONOMOUS REGION OF CHINA

        Cheng,Soo May,Yang,Li,Dong,Lin 세계문화관광학회 2007 Conference Proceedings Vol.8 No.0

        While western scholars such as Jamal and Gertz (1995), Tosun (2005), Fallon and Kriwoken (2003), usually presume that community participation is critical to sustainable tourism development, Chinese scholar Wenjun Li (2006) boldly states that it is possible for a community to achieve benefits of tourism development despite weak involvement in the planning and management of a tourist destination. Our survey of government officials, tourist business operators and residents in seven locations in the World Heritage-listed Turpan Valley in the Xinjiang province found that top-down, government-led participation is necessary and desirable, and does not detract from stakeholders' perception that they are sharing in the benefits of tourism development in the region.

      • 예술고등학교 학생들의 특기적성을 고려한 프로젝트형 물리 탐구학습

        양청규,이희복,김용복 공주대학교 과학교육연구소 2003 과학교육연구 Vol.34 No.-

        본 연구는 학습자 중심의 다양한 교수-학습 방법의 모색을 시도하는 교육 여건에 부응하여 물리학습에서 특기적성을 살린 프로젝트형 탐구학습 프로그램을 개발하여, 이를 예술계 고등하교 학생들에게 적용한 후, 학생들의 과학에 관련된 태도가 어떻게 변화했는지를 알아보고, 특기적성용 프로젝트 탐구학습에 대한 학생들의 반응을 살펴보았다. 따라서 본 연구에서는 학습자로 하여금 자신의 수준과 적성에 부합한 과제를 선택하도록 학습 동기를 유발하고 과제를 수행하는 과정을 단계적으로 수준을 높여가면서 학생들 스스로 문제를 해결해 나가는 자기 주도적인 학습이 가능하도록 하였다. 학생들의 프로젝트 수행결과에 대해서는 자기평가와 교사 면담을 통해 평가하도록 하였다. In order to contribute to contemporary educational environment searching for a variety of student-centered learning programs, this study attempts to make desirable project inquiry learning programs for physics educations which help to develop individual student's special ability and his or her aptitude. The programs were applied to the students of an Arts high school. After that this study tried to find out how students' attitudes toward science learning have changed, and how. they reacted to the "project inquiry-learning programs". In this study learners were allowed to choose an assignment for themselves equivalent to their academic ability and aptitude. This kind of activities motivates students for learning, makes them higher the standard of the process carrying out their assignments step by step, and finally enables them to have self-regulated learning, in which they settle the problems on their own. The result of the students' learning were evaluated by the self-evaluation and teachers' interviews with them.

      • 토끼에서 Etofenprox와 Spinosad 합제의 국소자극성 시험

        황윤환,김명석,송인배,박병권,양승호,임용현,송치용,안성한,남현수,임정교,정상일,명노일,윤효인 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2008 動物醫科學硏究誌 Vol.15 No.1

        This study was performed to evaluation the skin and eye irritation of etofenprox 8% and spinosad 4% combination in male New Zealand White rabbits. In skin irritation test, the combination of etofenprox and spinosad did not showed any change of body weight but caused slight skin irritation with the P.I.I. (primary irritation index) value 0.25. The etofenprox and spinosad combination showed severe eye irritation 1 h, 24 h, 48 h, and 72 h after ocular treatment, having the A.O.I. (acute ocular irritation) value of 37.3. Therefore, these result indicated that the combination of etofenprox and spinosad might be irritant formulation on eye and skin.

      • KCI등재

        Chemical Composition and Antibacterial Activities of Illicium verum Against Antibiotic-Resistant Pathogens

        Jyh-Ferng Yang,Cheng-Hong Yang,Hsueh-Wei Chang,Cheng-San Yang,Shao-Ming Wang,Ming-Che Hsieh,Li-Yeh Chuang 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.5

        In recent years, human pathogenic microorganisms have developed multiple drug resistance and caused serious nosocomial infections. In this study, we identified four new antimicrobial compounds from the Chinese herbal medicine Illicium verum and assessed their antibacterial efficacies. The supercritical CO2 and ethanol extracts of Illicium verum showed substantial antibacterial activity against 67 clinical drug-resistant isolates, including 27 Acinetobacter baumannii, 20 Pseudomonas aeruginosa, and 20 methicillin-resistant Staphylococcus aureus. The diethyl ether (EE) fraction obtained from partition extraction and supercritical CO2 extracts revealed an antibacterial activity with a minimum inhibitory concentration value of 0.15–0.70mg/mL and 0.11mg/mL, respectively. The EE fraction of I. verum showed synergetic effects with some commercial antibiotics. The antimicrobial mechanism was investigated with killing curves and scanning electron microscopy observation. The chemical components of the extracts were analyzed by spectrophotometry; (E)-anethole, anisyl acetone, anisyl alcohol, and anisyl aldehyde exhibited antibacterial activity against different clinical isolates. These extracts from I. verum can be further developed into antibiotic medicines due to their proven antibacterial activity.

      • Fenofibrate Increases Radiosensitivity in Head and Neck Squamous Cell Carcinoma via Inducing G2/M Arrest and Apoptosis

        Liu, Jia,Ge, Yang-Yang,Zhu, Hong-Cheng,Yang, Xi,Cai, Jing,Zhang, Chi,Lu, Jing,Zhan, Liang-Liang,Qin, Qin,Yang, Yan,Yang, Yue-Hua,Zhang, Hao,Chen, Xiao-Chen,Liu, Zhe-Ming,Ma, Jian-Xin,Cheng, Hong-Yan,S Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

        Radiation therapy is an important treatment for head and neck squamous cell carcinoma (HNSCC). However, how to promote radiation sensitivity in HNSCC remains a challenge. This study aimed to investigate the radiosensitizing effects of fenofibrate on HNSCC and explore the underlying mechanisms. HNSCC cell lines CNE-2 and KB were subjected to ionizing radiation (IR), in the presence or absence of fenofibrate treatment. Cell growth and survival, apoptosis and cell cycle were evaluated. In addition, CNE-2 cells were xenografted into nude mice and subjected to IR and/or fenofibrate treatment. The expression of cyclinB and CDK1 was detected by Western blotting. Our results showed that fenofibrate efficiently radiosensitized HNSCC cells and xenografts in mice, and induced apoptosis and G2/M arrest via reducing the activity of the CDK1/cyclinB1 kinase complex. These data suggest that fenofibrate could be a promising radiosensitizer for HNSCC radiotherapy.

      • Control Design for Robotic Human-Following and Obstacle Avoidance Using an RGB-D Camera

        Cheng-An Yang,Kai-Tai Song 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10

        The task of robotic human-following requires a mobile robot to detect and follow the selected target person and maintain an appropriate distance to the person. In practical applications, the robot must continuously estimate the target location considering unexpected obstacles to keep stable human-following control. This paper proposes to combine human-following control with obstacle avoidance, so that the robot can avoid obstacles while simultaneously follow the target person. In this design, obstacle as well as human features are obtained by using a RGB-D camera. A deep neural network(DNN) model works to detect and identify the user in the environment. An improved artificial potential field (APF) is applied to robot motion planning by integrating the target human position and obstacle information. Practical experiments on a mobile robot verified the proposed method. The robot can follow the user stably while avoiding obstacles in an indoor environment.

      • KCI등재

        Research on Dynamic Characteristics for Longwall Shearer Cutting Transmission System with Varying Cutting Speed

        Yang Yang,Hao Fan,Peng-cheng Ma 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.8

        A new longwall shearer cutting transmission system with variable cutting speed (LSCT-V) is presented to overcome the weaknesses of the traditional longwall shearer cutting transmission system (LSCT) with constant cutting speed. The dynamic model of the LSCTV and LSCT, which includes a cutting-motor rotator and drum, are established in AMESim, and the dynamic response of each system is analyzed using AMESim. Simulation results show that the function of frequency control for the designed LSCT-V system can be achieved, compared with the dynamic behavior of LSCT system under step torque load. The dynamic characteristics of the LSCT-V system are very close when working in constant or varying cutting speeds.

      • Antitumor Activity of Histone Deacetylase Inhibitor Trichostatin A in Osteosarcoma Cells

        Cheng, Dong-Dong,Yang, Qing-Cheng,Zhang, Zhi-Chang,Yang, Cui-Xia,Liu, Yi-Wen Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

        Background: Histone deacetylase (HDAC) inhibitors have been reported to induce cell growth arrest, apoptosis and differentiation of tumor cells. The present study aimed to examine the effects of trichostatin A (TSA), one such inhibitor, on the cell cycle, apoptosis and invasiveness of osteosarcoma cells. Methods: MG-63 cells were treated with TSA at various concentrations. Then, cell growth and apoptosis were determined by 3-(4, 5-dimethyl-2-thiazolyl)-2H-tetrazolium bromide (MTT) and TUNEL assays, respectively; cell cycling was assessed by flow cytometry; invasion assays were performed with the transwell Boyden Chamber system. Results: MTT assays revealed that TSA significantly inhibited the growth of MG-63 cells in a concentration and time dependent manner. TSA treated cells demonstrated morphological changes indicative of apoptosis and TUNEL assays revealed increased apoptosis of MG-63 cells after TSA treatment. Flow cytometry showed that TSA arrested the cell cycle in G1/G2 phase and annexin V positive apoptotic cells increased markedly. In addition, the invasiveness of MG-63 cells was inhibited by TSA in a concentration dependent manner. Conclusion: Our findings demonstrate that TSA inhibits the proliferation, induces apoptosis and inhibits invasiveness of osteosarcoma cells in vitro. HDAC inhibitors may thus have promise to become new therapeutic agents against osteosarcoma.

      • Causes and Impacts of Foreign Institutional Investors' Herding in the Taiwan Stock Market

        Yang-Cheng Lu,Hao Fang 한국재무학회 2011 한국재무학회 학술대회 Vol.2011 No.09

        This study extends Sias (2004) and Wylie (2005) to examine whether herding exists among foreign institutional investors (FIIs), what is the cause of their herding, and whether their herding is stable across both bullish or bearish periods or institutional types in the Taiwan stock market. By testing the cross-sectional dependence in the FIIs’ demand for stocks in two adjacent months and decomposing them into their own cascades and other cascades, we demonstrate that the FIIs’ cascades mainly result from their herding for securities traded at medium to high frequency even though their own cascades still exist. We find little evidence that FIIs’ herding behavior is driven by habit investing in stocks which FIIs trade with at least medium to high frequency. The momentum trading of FIIs is found to account for little of their herding, and the obviously positive relationship between the FIIs’ demand and their lag demand changes little, even with their momentum trading being taken into consideration. Moreover, FIIs are more likely to herd in large capitalization securities, and thus investigative herding, rather than informational cascades, is the main reason for herding among FIIs in the Taiwan stock market, contrary to the result put forward by Sias (2004) and Wylie (2005). One of our contributions may be to find that the phenomenon that FIIs’ cascades mainly result from their herding does not change in the bullish and bearish Taiwan stock market. However, since FIIs are more likely to herd in large-capitalization securities, their herding will obviously increase (decline) when they herd in large-capitalization (small-capitalization) stocks in the bullish (bearish) stock market period. This study further finds that FIIs and dealers are more likely to follow similar-type institutions than different-type institutions, respectively, which is consistent with the view proposed by Del Guercio (1996) and Bennett, Sias and Starks (2003) that institutional herding is driven by reputational or characteristic herding. Security dealers in Taiwan will tend more often to follow same-type herding while FIIs will more often negatively follow different-type herding, which implies that, contrary to FIIs, security dealers will exhibit the strongest tendency to herd especially in same-type institutions possibly due to reputation concerns, which is consistent with the view of investigative and reputational herding put forward by Sias (2004) and Wylie (2005).

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