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( Un Seok Lee ),( Won Sup Lee ),( Gyeong Won Lee ),( Jung Hun Kang ),( Myung Hee Kang ),( Se Il Go ),( Anna Lee ),( Hoon-gu Kim ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1
Monitoring cancer antigen 125 (CA-125) serum levels is very useful for determining how epithelial ovarian cancer is responding to treatment and for predicting a patient`s prognosis after treatment. An increase in CA-125 levels within patients in a remission is a strong predictor of the recurrence of ovarian cancer. However, while CA-125 is best known as a tumor marker for ovarian cancer, it may also be elevated in other various malignancies and in some benign conditions such as peritonitis, pancreatitis, chronic liver diseases, pelvic inflammatory diseases, or endometriosis. We describe herein a case of solitary intra-abdominal tuberculous lymphadenopathy mimicking a local relapse of epithelial ovarian cancer. A 51-year-old woman presented with progressive rise in serum CA-125. She had been diagnosed with advanced epithelial ovarian malignancy and undergone debulking surgery about 4 years ago. She had been given platinum-based adjuvant chemotherapy and achieved complete remission (CR). During regular follow-up in CR, a progressive rise in serum CA-125 was detected. The abdominal computed tomography (CT) showed a cystic mass, 3.6 cm in diameter, located adjacent to the right common iliac artery, suggesting a metastatic lymph node. We had planned second-look operation in settings of suspected focal recurrence of ovarian cancer, supported by evidence of rising CA-125 levels. However, the suspected tuberculous lesion was detected incidentally on preoperative chest CT. The patient had no symptoms and signs associated with tuberculosis (TB) and chest X-ray was also normal. We postponed the planned second-look operation and anti-TB medication was started. Mycobacterium TB was identified on culture of sputum specimens later. During anti-TB medication, the suspected metastatic isolated intra-abdominal lymphadenopathy improved and serum CA-125 level was also normalized. We emphasize here to consider not only the recurrence or progression of ovarian cancer itself but also benign conditions including TB in their differential diagnoses, when serum CA-125 level increases during the follow-up of epithelial ovarian cancer patients.
S-443 : Nilotinib-induced interstitial lung disease
( Un Seok Lee ),( Se Il Go ),( Won Sup Lee ),( Gyeong Won Lee ),( Jung Hun Kang ),( Myung Hee Kang ),( Jeong Hee Lee ),( Hoon Gu Kim ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1
Nilotinib is a second-generation tyrosine kinase inhibitor active in patients with chronic myeloid leukemia (CML) resistant to imatinib, and has been recently approved for newly diagnosed patients. We present a case of nilotinib-induced interstitial lung disease (ILD). A 67-year-old female patient was initially treated with imatinib for chronic-phase Philadelphia chromosomepositive (Ph+) CML. Imatinib was replaced by nilotinib because of hematological toxicity. The patient had received nilotinib for about 3 years without significant adverse effects. She visited the clinic due to chronic cough; chest X-ray revealed consolidations in both lung fields. Nilotinib-induced ILD was diagnosed based on intensive workup, including lung biopsy. She responded dramatically to corticosteroid therapy. To our knowledge, this is the first reported case of nilotinib-induced ILD in a patient with Ph+ CML. We emphasize that if unexplained lung abnormalities progress in patients receiving nilotinib, physicians should consider this potentially fatal complication in their differential diagnoses.
Seok Chan Hong(홍석찬),You Jin Hwang(황유진),Un Gu Kang(강운구) 한국컴퓨터정보학회 2019 韓國컴퓨터情報學會論文誌 Vol.24 No.8
The personalized meal service is being developed to prevent and alleviate illnesses according to the individual"s health condition. However, the current meal does not provide a fully customized service to individuals and a diet that meets the consumer"s information needs. The cause is the lack of information on the ingredients and the difficulty of comparative analysis between the materials. Therefore, in this study, we propose basic analysis process for basic information acquisition and database construction for food composition before providing personalized food. In this study, we investigated the content of carbohydrate, reducing sugar and protein as basic components of Grifola frondosa and investigate the content of polyphenol as a biological active ingredients. Respectively. Studies on the hypoglycemic effect of the diabetic rat model have been carried out in relation to the prevention of diseases. Based on the results of this study, it is also possible to obtain information on the basic ingredients of the food and to analyze the information on the content and activity of the biological active ingredients. Using animal models, information on disease prevention and mitigation was also available. The process introduced in this study is applied to various food materials, accumulating data, and utilizing Database, this results will be an excellent tool for providing more efficient service by providing a proper dietary composition for consumers.
Kang, Dong-Gue,Ko, Hyeyoon,Koo, Jahyeon,Lim, Seok-In,Kim, Jin Soo,Yu, Yeon-Tae,Lee, Cheul-Ro,Kim, Namil,Jeong, Kwang-Un American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.41
<P>For the development of anisotropic thermal interface materials (TIMs), a rod-shaped reactive monomer PNP-6MA is newly designed and successfully synthesized. PNP-6MA reveals a smectic A (SmA) mesophase between crystalline (K) and isotropic (I) phases. PNP-6MA can be oriented under a magnetic field (<I>B</I> = 2 T), and its macroscopic orientation can be robustly stabilized by in situ polymerization. Even without macroscopic orientations, the fabricated thermal conducting liquid crystal (TCLC) films show the outstanding thermal conductivity of 1.21 W/m K, which is higher than conventional organic materials. The thermal conductivity of uniaxially and macroscopically oriented TCLC films can be 2.5 W/m K along the long axis of mesogenic core. The newly developed TCLC film can be used as a TIM between a high-power light-emitting diode and a heat sink.</P> [FIG OMISSION]</BR>
O2RB 피처를 활용한 어안렌즈용 Visual-SLAM
강석운(Seok-Un Kang),이은종(Eun-Jong Lee),황성수(Sung-Soo Hwang) 제어로봇시스템학회 2022 제어·로봇·시스템학회 논문지 Vol.28 No.4
In this paper, we present an efficient visual simultaneous localization and mapping (SLAM) for a fisheye lens. A fisheye lens can obtain more information through a wide field of view (FoV) compared with a pinhole camera model. However, fisheye lenses has strong radial distortion, necessitating proper distortion correction. Pre-existing visual SLAMs for fisheye lenses have disadvantages in that either the correction processing speed is slow or the information of the input image is deformed in the correction process. We solve these problems by backprojecting the descriptor from a distortion-removed domain to the original distorted images using a parametric camera model. In addition, the multi-pinhole cube map model is employed to utilize the entire FoV without image distortion and obtain scale and rotation invariance. In the optimization process, more stable optimization is achieved using a new Jacobian calculation method suitable for a sphere model. The performance is evaluated in terms of the overall system processing time and error comparison between the camera pose and ground truth when creating the SLAM map. Experimental results indicate that our proposed method has a high processing speed while having a similar or better accuracy compared with another method.
출력전압 레벨 수를 증가시키기 위한 효율적인 멀티레벨 인버터 구조
홍운택(Un-Taek Hong),최원균(Won Kyun Choi),현석환(Seok Hwan Hyun),권철순(Cheol Soon Kwon),강필순(Feel-soon Kang) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7
본 논문에서는 풀-브리지 모듈과 양방향 스위치를 가지는 변형된 풀-브리지 모듈을 다단 결합시켜 15-레벨의 출력을 형성할 수 있는 혼합형 멀티레벨 인버터를 제안한다. 제안된 회로의 입력전압원의 크기가 서로 동일한 경우와 3의 배수 형태를 가지는 경우에 대한 특성을 분석하고 시뮬레이션 및 실험을 통해 가장 효율적인 혼합형 회로 구성을 제안한다.