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        여성 알코올 의존 환자의 임상적 특성에 관한 연구 : - 일 정신병원 입원환자를 중심으로 -

        성상경,신동환,송종호,이규항 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

        연구목적: 남. 여 알코올의존 환자의 인구통계학적 특성, 음주력, 가족력, 음주양상, 음주동기, 공유질병 등을 포함하는 임상적 특성의 차이 및 여성 알코올의존에 대한 질병양상과 그 가족의 태도를 파악함으로써 향후 여성 알코올의존 환자의 치료 대책수립을 위한 기초자료를 제공하는데 그 목적이 있다. 방 법: 1991년 1월1일부터 1996년 5월31일까지 일 정신병원에 입원 치료한 남. 여 각각 51명의 알코올의존 환자를 연구대상으로 하였으며, 연구방법으로 병력기록지 및 설문지 조사를 통한 자료 수집을 이용하였다. 양군간의 비교를 위해 남. 여 인원 및 나이를 통제하였고, 여성 알코올의존자의 평균 연령은 44.45±11.02세였고 남성 환자군의 평균 연령은 44.17±10.08이었다. 진단은 DSM-Ⅲ-R에 의해 이루어졌으며 대상자 모두는 알코올 의존의 진단기준을 만족하였다. 결 과: 여성 알코올의존자는 남성 알코올의존자에 비해 음주시작 연령이 늦었고 과거 음주기간은 짧았으며 일 음주량이 적었다. 그리고 여성 알코올의존자는 남성 알코올의존자에 비해 자발적 입원이 많았으며 입원후 금단증상, 알코올성 간염, 당뇨등 신체적 합병증이 적었다. 또한, 입원후 가족의 태도에서 가족의 이혼위협 등 치료에 비협조적인 경우가 남성 알코올의존자에 비해 많았으며, 과거력상 사별, 이혼, 남편의 구타 등 상실의 경험이 많았다. 결 론: 남. 여 알코올의존자간에 인구통계학적 특성, 임상 특성, 가족의 태도 등 여러가지 면에서 차이가 나는 것으로 나타났다. 여성 알코올의존자 집단은 가족의 죽음, 부부생활의 갈등과 같은 심리 사회적 좌절 경험이 더 많고 가족들이 더 비협조적이었다. 그러므로 치료자는 이러한 여성알코올의존자의 특성을 치료와 예방에 반영하고 이들에 대한 세심한 배려를 해야할 것이다. Objectives: This study aimed to provide a basic data of female alcoholics by understanding the gender differences of the clinical characteristics including demographic characteristics, alcoholic history, family history, drinking patterns, reasons for drinking, and comorbidity in male and female alcoholics. It also ained to establish the therapeutic plans through understanding the patterns of disease and the patterns of family cooperation in female alcoholics. Methods: The study subjects consisted of 51 male and female alcoholics admitted to a mental hospital from January 1, 1991 to May 31, 1996. Subjects were age-and sex-matched. We reviewed patients charts and administered questionaires. Mean age of female alcoholics was 44.45±11.02 years and that of male alcoholics was 44.17±10.08 years. All male and female patients met with the DSM-Ⅲ-R criteria of alcohol dependence. Results: Female alcoholics were later in drinking-onset age, and to had shorter duration of previous drinking history and less average amount of daily drinking than male alcoholics. And female alcoholics were found to seek treatment more voluntarily, and to have less frequent delirium tremens after admission and less medical complications such as hepatitis and diabetes mellitus. Also female alcoholics had more frustration experiences of separation such as death of family member, divorce, and husband`s physical abuse. Female alcoholic`s families had more uncooperative attitude toward treatment such as threat to divorce after admission. Conclusions: There were many differences between male and female alcoholics of demographic characteristics, clinical characteristics, and patterns of family cooperation. Female alcoholics were found to have more experiences of psychosocial frustration including death of family member and marital conflicts, and more uncooperative attitude of her family members. Therefore, it is required that therapists consider the characteristics of female alcoholics upon treatment and prevention, and have more concern about female alcoholics.

      • 비글개에서 신원방우황청심원의 급성 및 아급성독성시험

        성하정,권오경,방명주,곽형일,이진영,신대희,박대규,정규혁,윤효인,조명행 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

        Single and 4 weeks oral administration of New wonbangwoohwangchungsimwon (NSCH) which was used l-muscone as substitutive material of musk, to beagle dogs of both sexes were performed to investigate both acute and subacute toxicity. Beagle dogs (3 males and 3 females) in acute experiments were administered orally with sinlge dose of 2,000 ㎎/㎏ and groups of 9 male and 9 female beagle dogs in subacute experiments were given daily different dosage of NSCH, 160 ㎎/㎏/day (low dosage group), 400 ㎎/㎏/day (middle dosage group), 1,000 ㎎/㎏/day (high dosage group) once a day for 4 weeks by oral route according to the Established Regulation of Korea Food and Drug Administration (1996. 4. 16). LD_50 value for beagle dogs was more than 2,000 ㎎/㎏ per oral for both male and females. In animals administered with NSCH, there were neither dead animals nor significant changes of body weights. In addition, no differences were found between control and treated groups in clinical sign, urinalysis, eye examination, hematology, serum chemistry, organ weight and other fingings. No histological lesions were observed in both control and treatment groups. Above data strongly suggset that NSCH in beagle dogs is considered to be safe.

      • 위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

        김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

      • 트랙터의 로터리 驅動을 위한 PTO 시스템과 油壓驅動 시스템의 性能 試驗에 關한 硏究

        成始興,崔圭洪 建國大學校 附設 自然科學硏究所 1993 建國自然科學硏究誌 Vol.4 No.-

        엔진 회전속도 변동에 따른 PTO 회전수, PTO 토크, PTO 출력 및 연료 소비율을 측정하여 기계식과 유압식의 동력 특성을 비교, 분석한 결과는 다음과 같다. 1) 기계식, 유압식 모두 엔진의 회전 속도가 증가할수록 PTO 회전수는 증가하는 경향으로 나타났으며, 기계식이 변속단수 변동에 따른 엔진의 회전속도 폭이 안정적으로 나타난 대 반하여 유압식은 다소 크게 나타났다. 2) 엔진의 회전속도가 증가할수록 기계식, 유압식의 토크는 반비례 관계로 나타났다. 3) 최대 출력은 기계식의 경우 PTO 1, 2, 3단 순으로 나타난 데 비하여 유압식은 PTO 3, 2, 1단 순으로 나타나 PTO 변속 단수가 증가될수록 출력도 증가하는 것으로 나타났다. 4) 연료 소비율은 기계식, 유압식 모두 엔진의 회전수가 증가됨에 따라 연료 소비율은 어느 일정한 회전수 부근에서 최소가 된 후 다시 증가하는 경향으로 나타났다. 5) 유압구동 로터리의 효과적인 이용을 위해서는 유압펌프가 항상 고속으로 회전할 수 있도록 로터리는 어느 일정 회전속도를 유지시켜 작업하는 것이 필요할 것으로 판단되었다. 6) 유압식의 경우 유압펌프의 회전속도가 증가함에 따라 출력 및 연료 소비율이 향상되는 성으로 나타나 기계식에 비하여 효율이 크게 뒤떨어지지 않아 실용화의 가능성이 큰 것으로 생각되었다. The speed of revolution, the PTO torque, the PTO output power, and the specific fuel consumption caused by the variation in the revolution of an engine speed were measured. Therefore, the overall dynamic performance of the hydraulic PTO system was compared and analyzed with that of mechanical PTO system. The results are summarized as follows : 1) Both RPM of the hydraulic PTO and that of the mechanical one increased linearly as the engine speed increased. The engine speed from the variation of a mechanical type was saftly and small changed, but that of a hydraulic type was high changed. 2) Both torques of the hydraulic PTO system and those of the mechanical one decreased linearly as the engine speed increased. 3) The maximum power of the mechanical PTO system was the highest at the first gear of the mechanical one followed by the second one and the third one. However, that of the hydraulic PTO system was at the third gear followed by the second one and the first one. It means that the output power of a hydraulic PTO system increased as the variable PTO gear was increased. 4) After the specific fuel consumption decreased gradually to the specific point, which was required the lowest fuel consumption, then it increased as the engine speed increased. 5) To utilize effectively the hydraulic drive system, this system needs always to be kept revoluting constantly at an engine speed for hydraulic pump to rotate at the high speed. 6) The output power and the specific fuel consumption were improved by using the hydraulic system as the revolution of the engine speed was increased. The performance of hydraulic system was not significant of that of mechanical system. Therefore a hydraulic PTO system, which is convenient for a machine attached it to control automatically, would be utilized in future.

      • SCOPUSSCIEKCI등재

        소뇌에 발생한 Nocardiosis : 증례 보고 Case Report

        성연상,김상진,박순필,강재규,도종웅 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.6

        The authors report a extemely rare case of primary cerebellar nocardial abscess. Cerebral nocardiosis is rare disease and often fatal, and often fatal, and commonly spreaded from nocardiosis of lung or skin. Total excision of abscess and medication with sulfonamide is the treatment of choice. The patient was treated by continuous external dirainage with intermittent irrigation of abscess cavity by sulfonamide and given with sulfonamide for 10 months.

      • SCOPUSSCIEKCI등재

        골절 및 탈구 없는 경추손상의 치료

        성경훈,김상진,강재규,도종웅 대한신경외과학회 1989 Journal of Korean neurosurgical society Vol.18 No.7-12

        The authors analized the 98 cases of cervical spine injuries without fracture or dislocation by hyperflexion/hyperextension of the neck. The peak incidence of the age was in the second to fourth decades(69.4%). There was a male preponderance with a sex ratio of 1.8:1. Sources of trauma were motor vehicle accident, object falling on and motorcycle accident in the order of frequency. The common mechanisms of injury were flexion-extension, extension and flexion injury in the order of frequency. There were 10 cases of cervical cord injury without fracture or dislocation and operative management was given in 6 cases of them. The most common preexisting desease was congenital cervical stenosis. Surgical modality such as laminectomy, laminoplasty and anterior decompressive procedure made them improved. The authors discuss the mechanism of injury and surgical management of the patients with cervical cord injury in the abscence of concomittent fracture or dislocation.

      • SCOPUSSCIEKCI등재

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