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노덕영(DY Ro),이충훈(CH Lee),이종건(CK Lee),나종구(JG Na),김수평(SP Kim),이헌영(HY Lee),성인경(IK Sung),이병철(BC Lee),조성훈(SH Cho) 대한산부인과학회 1988 Obstetrics & Gynecology Science Vol.31 No.11
저자들은 ritodrine이 신생아 탄수화물 대사에 미치는 영향을 알아보고져 ritodrine주입을 받은 모성에서 태어난 신생아 40예를 실험군으로 그리고 ritodrine주입이 없었던 모성에서 태어난 신생아 18예를 대조군으로하여 다음과 같은 결론은 얻었다. 1. 실험군과 대조군간에는 성비, 임신주수, 신생아체중, 1분, 5분 Apgar score, 분만통의 유 무, 제왕절개술 빈도에서 유의한 차이가 없었다. 2. 혈당값은 실험군에서 37.9±2.4 ml/dl 대조군에서 63.1±13.0 ml/dl 로 두군간에는 통계적으 로 유의한 차이가 없었다. 3. 저혈당증의 발생빈도는 실험군 40예중에서 9예 대조군 18예중 2예에서 발생하여 두 군간 에는 P value 0.06으로 통계적으로 유의성은 없었다. 그러나 저혈당의 임상증상을 보인 3예 는 모두 실험군에서 발생하였다. 4. 실험군 혈당값중에서 질식분만 예들은 43.3±4.8 mg/dl, 분만통을 갖고 제왕절개술한 예들 에서 36.3±15.0 mg/dl 분만통없이 제왕절개술한 예들에서 35.9±2.7 mg/dl엿으며 각군간에 혈당값은 유의한 차이가 없었다. In order to assess the effect of ritodrine on neonatal carbohydrate metabolism the sugar levels of the neonate delivery by ritodrine treated women were compared with those of the neonate delivery by non-treated women The results were as follows; 1. There was no significantly difference in sex ratio, gesational age, birth weight 1-minute and 5-minute Apgar score the presence of labor and the number of cesarean section delivery between these two groups. 2. The sugar levels were 37.9±2.4 mg/dl in experimental group and 63.1±13 mg/dl in control group . But there was no significantly difference 3. The hypoglycemia occured in 9 of 40 cases of experimental group and 2 of 18 cases of control group , respectively. But there was no significantly difference. All of the symptomatic hypoglycemic cases (3cases) occured in the experimental group . 4. In the experimental group , the blood sugar levels of vaginal delivery group , cesarean section with labor group and cesarean section without labor group were 43.3±4.8 mg/dl, 36.3±15.0 mg/dl and 35.9±2.7 mg/dl ,respectively. There was no significantly difference in each other.
김도강,김수평,노덕영,유병대,이희중,한상하 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.11
Malignant ovarian lymphoma is a very rare entity and has a poor prognosis. A 32-year-old woman visited Taejon St, Mary`s hospital due to abdominal discomfort and pelvic mass. Under the impression of ovarian malignancy, total abdominal hysterectomy with bilateral salpingpo-ophorectomy, lymph node biopsy was done. Histopathologic and immunohis tochemical study demonstrated the tumor to be Burkitt`s lymphoma of the ovary with involvem ent of the uterus, tubes, and bone marrow. Now she got one cycle of CHOP(cyclophosphamide, adriamycin, vincristine, prednisolone) chemotherapy and then follow up via OPD. We have reported a case of Burkitt`s lymphoma of the ovary with a brief review of literature.
조기양막파수에 의한 양수내감염증 및 신생아 이환율을 진단하는데 있어서 CRP 및 LDH의 역할
김수평,이종건,김진홍,노덕영,박대순,김인재,이선희,나욱열 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.5
조기양막파수의 원인과 결과로서 양수내감염증은 논란의 여지가 있으며, 양수내감염증에 이차적으로 태아는 자궁내감염기회가 생길 수 있다. 양수내감염과 신생아 이환율을 진단하는데 있어서 신뢰도를 평가하기 위하여 조기파수된 산모와 이들 산모로부터 태어난 태아로부터 혈중 CRP와 혈중 및 양수의 LDH를 측정하여 다음과 같은 결론을 얻었다. 1. 조기양막파수 산모에서 양수내감염증은 CRP양성인 경우를 근거로 했을때 CRP양성인 경우가 8예로서 양수감염율은 28.6%였다. 2. 조기양막파수 산모에서 혈청 LDH값은 CRP양성군과 음성군간에 유의한 차이가 없었으나 400IU/L를 기준으로 한 양수내 LDH값과 양수내 LDH와 혈청 LDH비 1.5를 기준으로 구분한 경우 양 군간에 유의한 차이가 있었다.(P$lt;0.05) 3. 양막조기파수 산모에서 태어난 신생아의 체중은 2500gm이상인 경우가 CRP음성군에서 83.3%, CRP양성군에서 16.7%로 유의한 차이를 보였다. 4. 파막후 24시간이 지난 산모 22명으로부터 태어난 신생아에서 CRT양성율은 27.2%였으며,CRP양서인 신생아에서 폐염, B형 간염, 급성위장관염, 신생아고빌리루빈혈증 및 미숙아의 이환율을 보였다. Amniotic fluid infection as the cause and the consequence of premature rupture of membrane is controvertible. Following the amniotic fluid infection, the fetus was susceptible to the intrauterine infection. In order to evaluate their reliability as a diagnostic tool of amniotic fluid infection and neonatal morbidity, LDH in serum, amniotic fluid and CRP of pregnant women with premature rupture of membrane and neonates delivered from them were measured. The results were as follows: 1. CRP, microbiologic findings and amniotic fluid infection rate: Considering positive CRP as amniotic fluid infection, amniotic fluid infection rate was 28.6 % (8/28) Microorganisms were isolated from all of the amniotic fluid specimens of CRP(+) eight cases by bacterial culture, but above 20-30 WBC/ml was revealed by Gram stain in seven cases of the CRP (+) eight cases. 2. CRP, LDH and histopathological findings of placentas: There was no significant difference in the level of serum LDH between CRP (+) and CRP (-) group. LDH greater than 400 IU/L and the ratio of amniotic fluid LDH/ serum LDH greater than 1.5, have a high correlation with amniotic fluid infection. There was no correlation between histologic reports of chorioamniotis and amniotic fluid infection. Based on more than 100 WBC/ml in amniotic fluid, there was no correlation between the number of WBC and amniotic fluid infection. 3. Neonatal morbidity and mortality. There was no difference in gestational age, Apgar score at 5 min, RDS, neonatal sepsis between maternal CRP (+) group and CRP (-) group, but significant difference was found in the neonatal birth weight. 4. Neonatal morbidity from prolonged rupture of membrane: The incidence of CRP (+) in the infants delivered from mother with prolonged rupture of membrane are 27.2 % (6/22). The CRP (+) infants have neonatal morbidity such as pneumonia, hepatitis B, acute gastroenteritis, neonatal hyperbilirubinemia and prematurity. In conclusion, these results suggest that not only the measurements of CRP from the pregnant women with PROM and their neonate but also the measurements of LDH in the amniotic fluid and the rate of amniotic fluid LDH/serum LDH might be useful for a screening test of amniotic fluid infection and neonatal morbidity.