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최성우,이봉섭,곽명화,윤철종,박승조 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.2
Chromium occurs naturally in the earth's crust as well as in air, surface, and ground water. However, chromium is released to the environment in much larger amounts as a result of human activities. Hexavalent chromium, Cr(Ⅵ), is very soluble in water in natural environment and very toxic, carcinogenic, and mutagenic in animal and man. On the other hand trivalent chromium, Cr(Ⅲ), is less toxic and less soluble and thus is a lesser problem. This study has been carried out in order to reduce toxicity of Cr(Ⅵ) by an Escherichia coli strain. After adding E. Coli., the results were obtained from concentration of total Cr, Cr(Ⅵ). Cr(Ⅲ), pH, turbidity, and VSS in aerobic condition was summarized as follows : After 48hr aerobic condition in experiment of synthetic wastewater, the reduction rate of Cr(Ⅵ) was 20%. Also, the reduction rate of Cr(Ⅵ) was 60% in experiment of raw wastewater.
Proteomic Analysis of the Human Erythropoietin Transgenic Pig Testis
Myoung-Seob Choi,In-Sui Hwang,Eun-Jin Kim,Jae-Seok Woo,Seunghoon Lee,Min-Ji Kim,Min-Ji Kim,Sung-June Byun,Won-Kyoung Chang,Nam-Hyung Kim,Jin-Ki Park,Hwi-Cheul Lee 한국동물번식학회 2008 Reproductive & Developmental Biology(Supplement) Vol.32 No.2s
Proteomic Analysis of the Human Erythropoietin Transgenic Pig Testis
Myoung-Seob Choi,In-Sui Hwang,Eun-Jin Kim,Jae-Seok Woo,Seunghoon Lee,Min-Ji Kim,Min-Ji Kim,Sung-June Byun,Won-Kyoung Chang,Nam-Hyung Kim,Jin-Ki Park,Hwi-Cheul Lee 한국동물생명공학회(구 한국동물번식학회) 2008 Reproductive & developmental biology Vol.32 No.2
Choi, Il-Dong,Ryu, Ju-Hee,Lee, Dong-Eun,Lee, Myoung-Hee,Shim, Jae-Joong,Ahn, Young-Tae,Sim, Jae-Hun,Huh, Chul-Sung,Shim, Wang-Seob,Yim, Sung-Vin,Chung, Eun-Kyoung,Lee, Kyung-Tae Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-
<P>To evaluate the pharmacokinetics of compound K after oral administration of HYFRG and RG in humans, an open-label, randomized, single-dose, fasting, and one-period pharmacokinetic study was conducted. After oral administration of a single 3 g dose of HYFRG and RG to 24 healthy Korean males, the mean (±SD) of AUC<SUB>0–<I>t</I></SUB> and <I>C</I><SUB>max</SUB> of compound K from HYFRG were 1466.83 ± 295.89 ng·h/mL and 254.45 ± 51.20 ng/mL, being 115.2- and 80-fold higher than those for RG (12.73 ± 7.83 ng·h/mL and 3.18 ± 1.70 ng/mL), respectively; in case of Sprague Dawley rats the mean (±SD) of AUC<SUB>0–<I>t</I></SUB> and <I>C</I><SUB>max</SUB> of compound K from HYFRG was 58.03 ± 32.53 ng·h/mL and 15.19 ± 10.69 ng/mL, being 6.3- and 6.0-fold higher than those from RG (9.21 ± 7.52 ng·h/mL and 2.55 ± 0.99 ng/mL), respectively. <I>T</I><SUB>max</SUB> of compound K in humans and rats was 2.54 ± 0.92 and 3.33 ± 0.50 h for HYFRG and 9.11 ± 1.45 and 6.75 ± 3.97 hours for RG, respectively. In conclusion, the administration of HYFRG resulted in a higher and faster absorption of compound K in both humans and rats compared to RG.</P>
성장호르몬 결핍 성인에서 성장호르몬 투여가 심혈관 질환의 표지자에 미치는 영향
최형섭 ( Hyung Seob Choi ),김상수 ( Sang Soo Kim ),고근준 ( Kun Joon Ko ),이은재 ( Eun Jae Lee ),박일운 ( Il Woon Park ),박태운 ( Tae Woon Park ),한서구 ( Seo Goo Han ),우명렬 ( Myoung Lyeol Woo ),조지훈 ( Ji Hoon Cho ),홍성일 ( S 대한내과학회 2005 대한내과학회지 Vol.68 No.5
목적 : 성인 성장호르몬 결핍증 환자에서 3개월간의 성장호르몬 투여가 체중, 체질량지수, 허리둘레와 같은 신체검사결과, 혈당, 지질수치, 혈압 등의 잘 알려진 심혈관 질환의 위험인자들과 C-반응단백 및 PAI-1과 같은 염증반응인자들에 미치는 영향을 위약-대조군 연구를 통해 조사하였다. 방법 : 총 37명의 성인형 성장호르몬 결핍증 환자들과 65명의 정상인이 임상시험에 참여하였다. 시험시작 전과 3개월 후에 키, 몸무게, 허리둘레, 엉덩이둘레를 측정하였 Background : Subjects with growth hormone-deficiency (GHD) have increased cardiovascular mortality, and growth hormone (GH) replacement may modulate cardiovascular disease risk. Therefore, we evaluated the effects of GH administration on the markers of ca