Brain Topological Correlates of Motor Performance Changes After Repetitive Transcranial Magnetic Stimulation

Park, Chang-hyun,Chang, Won Hyuk,Yoo, Woo-Kyoung,Shin, Yong-Il,Kim, Sung Tae,Kim, Yun-Hee Mary Ann Liebert 2014 Brain connectivity Vol.4 No.4

<P>Repetitive transcranial magnetic stimulation (rTMS) influences the brain temporally beyond the stimulation period and spatially beyond the stimulation site. Application of rTMS over the primary motor cortex (M1) has been shown to lead to plastic changes in interregional connectivity over the motor system as well as alterations in motor performance. With a sequential combination of rTMS over the M1 and functional magnetic resonance imaging (fMRI), we sought changes in the topology of brain networks and specifically the association of brain topological changes with motor performance changes. In a sham-controlled parallel group experimental design, real or sham rTMS was administered to each of the 15 healthy subjects without prior motor-related dysfunctions, over the right M1 at a high frequency of 10 Hz. Before and after the intervention, fMRI data were acquired during a sequential finger motor task using the left, nondominant hand. Changes in the topology of brain networks were assessed in terms of global and local efficiency, which measures the efficiency in transporting information at global and local scales, respectively, provided by graph-theoretical analysis. Greater motor performance changes toward improvements after real rTMS were shown in individuals who exhibited more increases in global efficiency and more decreases in local efficiency. The enhancement of motor performance after rTMS is supposed to be associated with brain topological changes, such that global information exchange is facilitated, while local information exchange is restricted.</P>

펠던크라이스 기법, 탄성밴드 운동 및 복합운동 적용이 현대무용전공자의 체간근력에 미치는 영향

김채수(Kim Chae-Soo),권혜영(Kwon Hye-Young),이원재(Lee Won-Jae),조창모(Jo Chang-Mo),김진환(Kim Jin-Hwan),주성범(Ju Sung-Bum),이미경(Lee Mi-Kyoung) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.1

This study is carried out to examine the effect of applying Feldenkrais method, elastic band training and combined training on trunk muscle. The subjects of this study were 32 modern dance majors and they were divided into four groups which consists of 8 peoples each, Feldenkrais method group(modern dance + Feldenkrais method), elastic band training group(modern dance + elastic band training), combined training group(modern dance + Feldenkrais method + elastic band training), and control group(modern dance). Measurement variables which are trunk muscle were measured before training, and after 4 and 8 weeks training and the results are as follow: In the left muscle strength change at Centaur 0°, Feldenkrais method group, elastic band training group and combined training group showed significant increase after 8 weeks training compared to before training. In the right muscle strength change, Feldenkrais method group and combined training group had significant increase after 8 weeks training. In the left muscle strength change at Centaur 45°, Feldenkrais method group and combined training group showed significant increase after 8 weeks training compared to before training and after 4 weeks training. Also elastic band training group showed significant increase after 8 weeks training compared to before training. In the right muscle strength change, Feldenkrais method group and elastic band training group significantly increased after 8 weeks training compared to before training. In the left muscle strength change at Centaur 90°, Feldenkrais method group and combined training group showed significant increase after 4 and 8 weeks training compared to before training. In the right muscle strength change, Feldenkrais method group showed significant increase after 4 and 8 weeks training compared to before training, and elastic band training group significantly increased after 8weeks training compared to before training. In the left muscle strength change at Centaur 135°, there was no significant changes. In the right muscle strength change, elastic band training group and combined training group showed significant increase after 8 weeks training compared to before training. In the left muscle strength change at Centaur 180°, combined training group showed significant increase after 4 and 8 weeks training compared to before training. In the right muscle strength change, combined training group showed significant increase after 4 and 8 weeks training compared to before training. From above results, applying 8 weeks regular program of Feldenkrais method, elastic band training and combined training to modern dance majors showed positive changes on improvement of trunk muscle strength and physical strength. Also this study implemented to verify the effects of trunk muscle strength and body balance through supplementary training program, and showed the effects in the training group and control group after 8 weeks trunk muscle strengthening program. Feldenkrais method, elastic band training and combined training are very effective to improve trunk muscle strength of modern dance majors so that continuous implementation and application of these effective training program shall be provided for strengthening trunk muscle.

Seismic stratigraphic reconstruction of Plio-Quaternary depositional sequences on the continental shelf of Korea Strait

Yoo, Dong-Geun,Kim, Kyoung-Jin,Lee, Gwang-Soo,Kang, Nyeon-Keon,Yi, Bo-Yeon,Kim, Gil-Young,Chang, Se-Won,Kim, Han-Joon Elsevier 2017 Quaternary international Vol.459 No.-

<P><B>Abstract</B></P> <P>The Korea Strait is a seaway connecting the East Sea with the East China Sea. The Plio-Quaternary stratigraphy and sedimentation on the Korea Strait shelf was studied using a dense network of high-resolution, single-channel seismic reflection profiles. The shelf sequences above the acoustic basement consist of seven depositional sequences separated by erosional unconformities corresponding to falls in sea level. Individual sequences are characterized by well-stratified and complex sigmoid-oblique prograding reflection configurations, reflecting a history of upbuilding and outbuilding in response to repetitive transgressive and regressive events driven by sea level changes. During the regression to lowstand of sea level, lowstand prograding wedges were formed seaward along the present shelf margin, whereas during the highstand of sea level, as in the present condition, highstand deposits were deposited in the inner shelf along the coast. However, as the subsequent regression began, the inner-shelf highstand deposits were severely eroded out and/or formed a condensed section. Volumetrically, the forced regressive and lowstand systems tracts are the most important components of the Korea Strait. Consequently, the Plio-Quaternary sequence in this area consists of a succession of stacked progradational lowstand wedges, mainly formed during the regression and lowstand of sea level.</P>

기후변화와 키메라현상에 대한 계층 간의 관계인식

백정애(Jungae Baik),김인경(In Kyoung Kim),김진영(Jin Yung Kim),노용환(Yong Hwan Noh),배선영(Sunyoung Bae),우명원(Myoung Won Woo),장혁기(Hyukki Chang),조성돈(Sung Don Cho),장매희(Maehee Chiang) 인간식물환경학회 2011 인간식물환경학회지 Vol.14 No.3

This study was investigated to research the basis of interdisciplinary fusion through the survey on the basis of the answers of professionals and general public, gender, humanities, science and engineering about the question of climate change and chimera which is one of the various phenomena that affect the human life. All respondents’ perceptions of climate change was high and natural disasters was showed the most destruction according to climate change. The answer of awareness of climate change and the damage, chimerism was significant differences between age groups sex, specialized domain-specific individuals. In addition, a group of respondents for science and engineering professionals was higher for awareness of climate change and the chimerism and heir negative opinion for chimerism was relatively low in comparison of other research groups.

A preliminary study in melasma following INMODE forma procedure

( Soon-hyo Kwon ),( Je-byeong Chae ),( Jung-won Shin ),( Jung-im Na ),( Chang-hun Huh ),( Kyoung-chan Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Melasma is a common hypermelanosis that frequently appears on the face. In recent studies, it is suggested that dermal structural alteration, including solar elastosis and basement membrane disruption, may have an important role in the pathogenesis of melasma. Forma device (InMode Inc, Richmond Hill, ON, Canada, North America) is a radiofrequency dermal heating device used on facial wrinkles and rhytides. Objectives: The aim of this study was to evaluate the effects of Forma device on melasma in a small group of volunteers. Methods: All volunteers were treated 4 times at 3 weeks intervals. Every visit, melanin index and erythema index was measured to assess the improvement in hyperpigmentation and erythema. Clinical photos were evaluated to estimate the degree of skin changes. Results: Clinical and instrumental evaluation showed that melasma improved after INMODE forma treatment. Conclusion: We suggest that treatment with Forma device may have beneficial effects on melasma by dermal remodeling and direct heat delivery on melanocytes.

뇌실-복강 단락술 후 증상 호전 없었던 Normal Pressure Hydrocephalus 환자의 치험 1례

윤경선,권건록,한창호,정승현,신길조,이원철,정현정,Yoon, Kyoung-Sun,Kwon, Gun-Rok,Han, Chang-Ho,Jung, Seung-Hyun,Sin, Gil-Jo,Lee, Won-Chul,Jung, Hyun-Jung 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.4

The basic mechanism of normal pressure hydrocephalus(NPH) is found in an impediment to CSF absorption. In about half of the cases, the etiology remains obscure. NPH is more frequently found in elderly people. The main symptoms are gait disturbances, urinary incontinence and various degree of cognitive changes. The current treatment is ventriculo-peritoneal shunting, ideally using an adjustable valve. In about half of surgical operations, results are poor. Hyeongbangjihwang-tang(荊防地黃湯) is used to treat Soyangin(少陽人) weakness(虛弱) and edema(浮腫). It is and important Gang-Yin(降陰) medicine. A Soyangin patient diagnosed with NPH, who had undergone surgery for ventriculo-peritoneal shunting, was treated with Hyeongbangjihwang-tang. Significant improvement of clinical symptoms was seen, so it is here reported.

프로스타글란딘 유도체의 합성과 그의 생물학적 활성에 관한 연구 2. 위궤양과 위산분비에 대한 프로스타글란딘 유도체의 효과

조태순(Tai Soon Cho),이선미(Sun Mee Lee),함원훈(Won Hun Ham),이병무(Byung Mu Lee),김경례(Kyoung Rae Kim),지상철(Sang Cheol Chi),고준일(Jun Ill Ko),박인(In Park),오창영(Chang Young Oh),박호군(Ho Koon Park),김형자(Hyoung Ja Kim),이향우(H 한국응용약물학회 1995 Biomolecules & Therapeutics(구 응용약물학회지) Vol.3 No.1

The antiulcer effects of newly synthesized prostaglandin derivatives were investigated in various experimental ulcer models and on gastric secretion in rats. HK-3 and HK-4, PGE₂ derivatives, prevented the formation of acute gastric ulcer induced by ethanol or aspirin in pylorus-ligated rats. The ulcer formation was moderately inhibited by HK-1 and HK-2, PGF_(2α) derivatives, and aggravated by SK-1, SK-2 and SK-3, PGF_(2α) derivatives. HK-3 and HK-4 reduced the volume, acid output and pepsin output of gastric juice in pylorus-ligated rats. The gastric perfusion with physiologic saline(pH 6.0) showed relatively constant acid secretion and indomethacin increased the acid secretion. The acid secretion was markedly decreased by PGE₂ but PGF_(2α) caused little change. Prostaglandin derivatives, especially HK-3 and HK-4, significantly inhibited the acid secretion induced by indomethacin. The results show that, PGE₂ derivatives, HK-3 and HK-4, inhibit acid secretion and also have protective effects on gastric ulceration induced by ethanol or aspirin.

혈액투석 유지 요법 환자에서 하대정맥 직경과 좌심실 비대와의 관계

신진호(Jin Ho Shin),박찬현(Chan Hyun Park),최정혜(Jung Hye Choi),이창화(Chang Hwa Lee),강경원(Kyoung Won Kahng),김상목(Sang Mok Kim),강종명(Chong Myung Kang),박한철(Han Chul Park),장성렬(Sung Ryul Chang),이방헌(Bang Hun Lee) 대한내과학회 1998 대한내과학회지 Vol.55 No.5

N/A Background: Volume overload is one of the most important, correctable factor far blood sure control in hemodialysis patient. But objective parameter for the ideal body weight is not available in clinical field yet. Recently inferior vena caval examination became a possible candidate for an objective parameter for intravascular volume status. Therefore we investigated how inferior vena cava changes during hemodialysis compared with total amount of ultrafiltration and ANP, and also the effect of changes of IVC diameter on LVK Methods: 43 patients on stable maintainance hemodialysis were enrolled. Among them, 21 patients were on antihypertensive medication. Just before and after the hemodialysis, inferior vena cava diameter, plasma atrial natriuretic peptide and left ventricular mass index were measured for each patient. Inferior vena cava was examined at the level just below the hepatic vein during quiet respiration and left ventricular mass index was calculated. Results- Inferior vena cava at expiration(IVCe) was significantly decreased during hemodialysis(before hemodialysis 21.9 4.9 mm, after hemodialysis 18.3 4.4 mm, p = 0.02). Collasibility index was significantly increased during hemodialysis (before hemodialysis 0.24 0.15, after hemodialysis 0.41 0.19, p< 0.001). Atrial natriuretic peptide(ANP) was significantly decreased during hemodialysis (before hemodialysis 252.3±119.0 pg/ml, after hemodialysis 185.6±93.2 pg/ml, p<0.001). Total ultrafiltration amount was significantly correlated with collapsibility change(r=-0.40) and change of ANP(r=-0.41). Left ventricular mass index was correlated with interdialysis weight gain(r=0.39, p<0.05), IVCe after hemodialysis(r=0.48, p<0.05) in univariate analysis but not in multivariate analysis. Conclusion: Collapsibility index of inferior vena cava, IVC diameter and ANP changes reflect the volume change during the hemodiaylsis. Therefore 1VC examination can be an objective parameter for volume change during hemodialysis. Postdialysis 1VCe correlates weakly with left ventricular mass index but it cannot be an independant risk factor for left ventricular hypertrophy in our study.

Ceramic-on-Ceramic Total Hip Arthroplasty: Minimum of Six-Year Follow-up Study

Won Sik Choy,김갑중,이상기,Kyoung Wan Bae,Yoon-Sub Hwang,Chang Kyu Park 대한정형외과학회 2013 Clinics in Orthopedic Surgery Vol.5 No.3

Background: This study examines the clinical and radiologic results of ceramic-on-ceramic total hip arthroplasties with regard towear, osteolysis, and fracture of the ceramic after a minimum follow-up of six years. Methods: We evaluated the results of a consecutive series of 148 primary ceramic-on-ceramic total hip arthroplasties that hadbeen performed between May 2001 and October 2005 in 142 patients. The mean age was 57.2 years (range, 23 to 81 years). Themean follow-up period was 7.8 years (range, 6.1 to 10.1 years). Preoperative diagnosis was avascular necrosis in 77 hips (52%),degenerative arthritis in 36 hips (24.3%), femur neck fracture in 18 hips (12.2%), rheumatoid arthritis in 15 hips (10.1%), and septichip sequelae in 2 hips (1.4%). Clinical results were evaluated with the Harris hip score, and the presence of postoperative groinor thigh pain. Radiologic analysis was done with special attention in terms of wear, periprosthetic osteolysis, and ceramic failures. Results: The mean Harris hip score improved from 58.3 (range, 10 to 73) to 92.5 (range, 79 to 100) on the latest follow-up evaluation. At final follow-up, groin pain was found in 4 hips (2.7%), and thigh pain was found in 6 hips (4.1%). Radiologically, all femoralstems demonstrated stable fixations without loosening. Radiolucent lines were observed around the stem in 25 hips (16.9%), andaround the cup in 4 hips (2.7%). Endosteal new bone formation was observed around the stem in 95 hips (64.2%) and around thecup in 88 hips (59.5%). No osteolysis was observed around the stem and cup. There were 2 hips (1.4%) of inclination changes ofacetabular cup, 2 hips (1.4%) of hip dislocation, 1 hip (0.7%) of ceramic head fracture, and 1 hip (0.7%) of squeaking. The Kaplan-Meier survival rate of the prostheses was 98.1% at postoperative 7.8 years. Conclusions: The ceramic-on-ceramic total hip arthroplasty produced excellent clinical results and implant survival rates with nodetectable osteolysis on a minimum six-year follow-up study. The ceramic-on-ceramic couplings could be a reasonable option ofprimary total hip arthroplasty for variable indications.

Antioxidant activity of sesame cake extracts obtaining using various ethanol extraction conditions

Kyoung Ah Lee,Keun Young Min,Na-Kyoung Lee,Kyung Hoon Chang,Seong Jun Cho,Won Dae Chung,Hyun-Dong Paik 한국식품과학회 2017 한국식품과학회지 Vol.49 No.3

The antioxidant activities of sesame cake extracts prepared using ethanol and hot water were evaluated. Seventy percent-ethanol extracts yielded the highest total phenolic (96.56 mg/g extract) and flavonoid (8.35 mg/g extract) contents. In the β-carotene bleaching and ferric thiocyanate test, 30%-, 50%-, and 70%-ethanol extracts exhibited higher antioxidant activity than that exhibited by 90%-ethanol extracts. However, 90%-ethanol extracts showed greater antioxidant activities in phenyl-2-picryl-hydrazyl free radical scavenging test and thiobarbituric acid test using corn oil. The antioxidant activities of sesame cake extracts did not correlate with the total phenolic and flavonoid contents; however, the results suggest that oxidative stability may be improved by sesame cake extracts.