Reconfigurable Optical Delay Lines Based on Single Folded Waveguides

Linjie Zhou,Tong Ye,Jianping Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.42

We propose a novel single folded waveguide-based reconfigurable optical delay line. Due to waveguide self-coupling, light travels back and forth along the waveguide, forming resonances. With two phase shifters embedded in the waveguide, resonance modes and coupling can be conveniently controlled. Under proper phases, the delay line can be reconfigured to perform various types of delays. In particular, when the resonance input and mutual coupling strengths are properly matched, the group delay dispersion can be significantly reduced, favoring an optical signal delay with low distortion. The group delay can be continuously tuned at low tuning power by changing the phases.

Exercise-induced FNDC5/irisin protects nucleus pulposus cells against senescence and apoptosis by activating autophagy

Zhou Wenxian,Shi Yifeng,Wang Hui,Chen Linjie,Yu Caiyu,Zhang Xufei,Yang Lei,Zhang Xiaolei,Wu Aimin 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Intervertebral disc degeneration (IVDD) is a major cause of low back pain (LBP), and excessive senescence and apoptosis of nucleus pulposus (NP) cells are major pathological changes in IVDD. Physical exercise could effectively delay the process of intervertebral disc degeneration; however, its mechanism is still largely unknown. Irisin is an exercise-induced myokine released upon cleavage of the membrane-bound precursor protein fibronectin type III domain-containing protein 5 (FNDC5), and its levels increase after physical exercise. Here, we show that after physical exercise, FNDC5/irisin levels increase in the circulation and NP, senescence and apoptosis are reduced, autophagy is activated in NP tissue, and the progression of IVDD is delayed. Conversely, after knocking out FNDC5, the benefits of physical exercise are compromised. Moreover, the overexpression of FNDC5 in NP tissue effectively alleviated the degeneration of the intervertebral disc (IVD) in rats. By showing that FNDC5/irisin is an important mediator of the beneficial effects of physical exercise in the IVDD model, the study proposes FNDC5/irisin as a novel agent capable of activating autophagy and protecting NP from senescence and apoptosis.

Improved performance of polyamide nanofiltration membranes by incorporating reduced glutathione during interfacial polymerization

Zhiwei Jiao,Linjie Zhou,Mengyuan Wu,Kang Gao,Yanlei Su,Zhongyi Jiang 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12

Inspired by the specific amino acid sequence Asn-Pro-Ala (NPA) of water channel aquaporins (AQPs), we fabricated polyamide (PA) nanofiltration (NF) membranes by introducing reduced glutathione (GSH) in interfacial polymerization (IP) method. Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectrometry (XPS), scanning electron microscope (SEM), atomic force microscopy (AFM), zeta potential and static water contact angle measurement were employed to characterize the chemical composition, morphology, electronegativity and hydrophilicity of the NF membranes. The water flux of GSH/PIP-TMC NF membrane reached 32.00 L m2 h1 at 0.2MPa, which was approximately twice than that of pristine PIP-TMC NF membrane when the ratio of GHS to piperazidine (PIP) was 40% during IP process. More water channels were built as GSH was embedded into PA layer. The fabricated NF membranes also took on potent rejection for dyes and Na2SO4. This study presents a simple and facile method to simulate water channels-based biological materials which may find potential application in water treatment.

Expression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development

Zhong, Tao,Zhao, Wei,Zhou, Zhongqiang,Li, Li,Wang, Linjie,Li, Hua,Zhang, Hongping Korean Society of Animal Science and Technology 2015 한국축산학회지 Vol.57 No.8

Background: The physiologic characteristics of the cashmere trait and many of the differentially expressed genes relevant to hair cycling have been extensively studied, whereas genes involved in the prenatal development of hair follicles have been poorly investigated in cashmere goats. The aim of this study, therefore, was to quantify the time-course changes in the expressions of $TR{\alpha}$ and CRABPII genes in the fetal skin of Chinese cashmere goats at the multiple embryonic days (E70, E75, E80, E90, E100, E120 and E130) using real-time quantitative PCR (RT-qPCR). Results: RT-qPCR showed that $TR{\alpha}$ was expressed at E70 with relatively high level and then slightly decreased (E75, E80, and E90). The highest expression of $TR{\alpha}$ mRNA was revealed at E130 (P > 0.05). The expression pattern of CRABPII mRNA showed an 'up-down-up' trend, which revealed a significantly highest expression at E75 (P < 0.05) and was down-regulated during E80 to E120 (P < 0.05) and mildly increased at E130, subsequently. Conclusion: This study demonstrated that $TR{\alpha}$ and CRABPII genes expressed in different levels during prenatal development of cashmere. The present study will be helpful to provide the comprehensive understanding of $TR{\alpha}$ and CRABPII genes expressions during cashmere formation and lay the ground for further studies on their roles in regulation of cashmere growth in goats.

Effects of Loading Rates on the Hysteretic Response of Resilient Variable Friction Dampers

Yongwei Wang,Zhen Zhou,Linjie Huang 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.5

A novel resilient variable friction damper (RVFD) with a simple construction was proposed. To analyze the eff ects of loading rate on the stability and energy dissipation performance of the RVFD, two RVFDs were tested under diff erent loading rates and the hysteretic behaviors of the compared with that of the traditional constant friction dampers. Then the peak force, energy dissipation behavior, uneven gap opening of the grooved outer plates (GOPs), and performance of the disc springs under diff erent loading rates were studied. The results show that although no self-centering system was provided, only the RVFDs without a self-centering system still can exhibit stable self-centering performance and eff ective energy dissipation behaviors, especially with due to the using e of athe grooved steel plates with greater groove angle. When the loading rate is less than 10 mm/s, the peak forces of the RVFD slightly decrease with the increase in loading rates, while when the loading rate is greater than 10 mm/s, its eff ects could be neglected. The uneven gap opening of the GOPs infl uences the clamping forces of the disc springs in the bolts under diff erent loading amplitudes. The disc springs in the RVFDs not only provide the increasing clamping forces for energy dissipation and the restoring forces for self-centering behavior, but also dissipate the energy, which accounts for about 10% of the total energy dissipation of the RVFD.

Open Access : Expression patterns of TRα and CRABPII genes in Chinese cashmere goat skin during prenatal development

( Tao Zhong ),( Wei Zhao ),( Zhongqiang Zhou ),( Li Li ),( Linjie Wang ),( Hua Li ),( Hongping Zhang ) 한국동물자원과학회(구 한국축산학회) 2015 한국축산학회지 Vol.57 No.28

Background: The physiologic characteristics of the cashmere trait and many of the differentially expressed genes relevant to hair cycling have been extensively studied, whereas genes involved in the prenatal development of hair follicles have been poorly investigated in cashmere goats. The aim of this study, therefore, was to quantify the time-course changes in the expressions of TRα and CRABPII genes in the fetal skin of Chinese cashmere goats at the multiple embryonic days (E70, E75, E80, E90, E100, E120 and E130) using real-time quantitative PCR (RT-qPCR). Results: RT-qPCR showed that TRα was expressed at E70 with relatively high level and then slightly decreased (E75, E80, and E90). The highest expression of TRα mRNA was revealed at E130 (P > 0.05). The expression pattern of CRABPII mRNA showed an ``up-down-up`` trend, which revealed a significantly highest expression at E75 (P < 0.05) and was down-regulated during E80 to E120 (P < 0.05) and mildly increased at E130, subsequently. Conclusion: This study demonstrated that TRα and CRABPII genes expressed in different levels during prenatal development of cashmere. The present study will be helpful to provide the comprehensive understanding of TRα and CRABPII genes expressions during cashmere formation and lay the ground for further studies on their roles in regulation of cashmere growth in goats.