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김정수,김인아,이수진,김용규,박시복,고재우,송재철 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4
Objective: This study was carried out to investigate if the measurement of range of motion(ROM) could be applied in the diagnosis of Myofascial Pain Syndrome(MPS) and to determine the severity by analyzing ROM in MPS patients. Methods: The study subjects were 476 female telephone number information service workers. Southampton Protocol and Pittsburgh Protocol were used to diagnose MPS and to measure ROM. ROMs were measured by 2 inclinometers exercising each shoulder passively and actively in 5 directions ; abduction, forward flexion, extension, external rotation, and internal rotation. Results: Compared to the normal group (n=147), the mean of right side ROM in the subjects (n=270) with same side MPS was 2.1˚ (SD=11.5) lesser in active extension and 1.7˚ (SD=10.4) lesser in passive extension. Compared to the mild group (n=210), the mean of right side ROM in the patients with same side severe MPS (N=58) was lesser in all directions. Especially in active forward flexion, passive forward flexion, active extension, passive extension and active external rotation, ROM in the subjects with severe MPS was lesser by 6.5˚ (SD=13.1), 5.1˚ (SD=12.8), 5.9˚ (SD=11.8), 5.0˚ (SD=10.6) and 3.9˚ (SD=9.8), respectively, than those of the subjects with mild MPS. Compared to the subjects with left side mild MPS(n=172), ROM in the subjects with left side severe MPS (n=59) was 5.3˚ (SD=13.3) lesser in active forward flexion. Conclusions: In this study, ROMs in the subjects with severe MPS tended to be lesser than those in mild patients. This tendency was more prominent in the right side than the left, active range of motion than passive and forward flexion and extension than others. The results of this study are expected to help diagnose shoulder MPS and determine severity.
KIM, Bongtae,AHN, Kyoung Kyu,HA, Yooncheol,LEE, Yong Hoon,KIM, Duyeol,LIM, Jeong Han,KIM, Sung-Hoon,KIM, Mi-Young,CHO, Kyung-Dong,LEE, Bog-Hieu,CHAE, Chanhee Japanese Society of Veterinary Science 2009 The Journal of veterinary medical science Vol.71 No.5
<P>The relationship between tumor necrosis factor (TNF)-α level, body temperature, and pulmonary lesion score was determined in 3-week-old pigs inoculated intranasally with swine influenza virus (SIV) subtype H1N2. The expression of TNF-α was measured in bronchoalveolar lavage (BAL) fluids by enzyme-linked immunosorbent assay and lung tissues by immunohistochemistry. In BAL fluid, TNF-α concentration was maximal at 1 days post-inoculation (dpi), declined markedly by 3 dpi (<I>P</I><0.05) and steady thereafter. Mean rectal temperatures were above 40°C for the infected groups at 1 dpi and declined markedly by 3 dpi. The body temperatures were correlated with the levels of TNF-α in BAL fluids from pigs experimentally infected with SIV (<I>r</I><SUB>s</SUB>=0.9754, <I>P</I><0.05). The pulmonary lesion scores were correlated with the means of positive cells by immunohistochemistry for TNF- α (<I>r</I><SUB>s</SUB>=0.9949, <I>P</I><0.001). The results suggest that the expression of TNF-α protein plays an important role in induction of pulmonary lesion and clinical sign such as fever in SIV infection.</P>
Outcomes of deceased donor liver transplantation from elderly donors
Kim Minjae,Hwang Shin,Ahn Chul-Soo,Kim Ki-Hun,Moon Deok-Bog,Ha Tae-Yong,Song Gi-Won,Jung Dong-Hwan,Park Gil-Chun,Yoon Young-In,Kang Woo-Hyoung,Cho Hwui-Dong,Na Byeong-Gon,Kim Sang Hoon,Lee Sung-Gyu 대한이식학회 2021 Korean Journal of Transplantation Vol.35 No.2
Background: Favorable outcomes achieved after deceased donor liver transplantation (DDLT) suggest that use of elderly donors may be an effective way to expand donor pool. Methods: This was a retrospective analysis of adult DDLT using elderly donors. It was a double-arm study that compared posttransplant outcomes to ascertain whether use of elderly donors (aged ≥76 years) has adverse effects on outcome of DDLT. Elderly donor study group included 14 donors aged ≥76 years and elderly donor control group comprised 39 donors aged 66–75 years. Results: Mean donor age of the study and control groups was 78.2±3.1 years and 68.9±2.7 years, respectively (P<0.001). Other clinical parameters were comparable between these two donor groups. The 1-, 3-, and 5-year graft survival rates in the elderly study group were 83.6%, 59.7%, and 59.7%, respectively, and those in the elderly control group were 79.4%, 68.1%, and 59.6%, respectively (P=0.97). The overall 1-, 3-, and 5-year survival rates after donation from elderly study group were 83.6%, 59.7%, and 59.7%, respectively, and those after donation from control group were 79.3%, 72.1%, and 64.1%, respectively (P=0.74). Regarding overall patient survival, univariate analysis identified pretransplant requirement for ventilator support (P=0.021) and pretransplant renal replacement therapy (P=0.025) as statistically significant risk factors; however, neither was significant on multivariate analysis. Conclusions: The results of this study suggest that using an elderly donor graft might not worsen the posttransplant outcomes significantly; thus, advanced age per se may not be an exclusion criterion for organ donation.
Yong-Kyu Chung,Shin Hwang,Chul-Soo Ahn,Ki-Hun Kim,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Young-In Yoon,Woo-Hyoung Kang,Hwui-Dong Cho,Jin Uk Choi,Minjae Kim,Sang Hoon Kim,By 대한외과학회 2021 Annals of Surgical Treatment and Research(ASRT) Vol.101 No.1
Purpose: When splitting a liver for adult and pediatric graft recipients, the retained left medial section (S4) will undergo ischemic necrosis and the right trisection graft becomes an extended right liver (ERL) graft. We investigated the fates of the retained S4 and its prognostic impact in adult split liver transplantation (SLT) using an ERL graft. Methods: This was a retrospective analysis of 25 adult SLT recipients who received split ERL grafts. Results: The mean model for end-stage liver disease (MELD) score was 27.3 ± 10.9 and graft-recipient weight ratio (GRWR) was 1.98 ± 0.44. The mean donor age was 26.5 ± 7.7 years. The split ERL graft weight was 1,181.5 ± 252.8 g, which resulted in a mean GRWR of 1.98 ± 0.44. Computed tomography of the retained S4 parenchyma revealed small ischemic necrosis in 16 patients (64.0%) and large ischemic necrosis in the remaining 9 patients (36.0%). No S4-associated biliary complications were developed. The mean GRWR was 1.87 ± 0.43 in the 9 patients with large ischemic necrosis and 2.10 ± 0.44 in the 15 cases with small ischemic necrosis (P = 0.283). The retained S4 parenchyma showed gradual atrophy on follow-up imaging studies. The amount of S4 ischemic necrosis was not associated with graft (P = 0.592) or patient (P = 0.243) survival. A MELD score of >30 and pretransplant ventilator support were associated with inferior outcomes. Conclusion: The amount of S4 ischemic necrosis is not a prognostic factor in adult SLT recipients, probably due to a sufficiently large GRWR.
두 개의 EPPR 밸브가 적용된 정/역 가변형 사판식 액셜 피스톤 펌프 시스템 모델링
김용길(Yong-Gil Kim),김수태(Soo-Tae Kim),함영복(Young-Bog Ham),윤소남(So-Nam Yun),손호연(Ho-Yeon Son) 유공압건설기계학회 2020 드라이브·컨트롤 Vol.17 No.1
This study addresses the modeling of a bi-directional outlet variable swash plate type axial piston pump with two EPPR valves and an analysis of the response characteristics to the angle control of that pump. In this paper, the combination of the EPPR valve and double rod type piston is referred to as the EPPR regulator. The EPPR regulator is compact and inexpensive, and has good responsiveness. Under actual pump operating conditions, because of the various external conditions of the pump, inertia is applied to the swash plate, generating the tilting torque. Also, the tilting torque can delay or shorten the response characteristics of the regulator. So we validated them through the analysis using SimulationX and these results allow users to freely integrate the EPPR regulator into the desired system.
어린이와 청소년의 비알콜성음료 섭취에 따른 다량무기질 섭취량 평가
김성단(Kim, Sung Dan),문현경(Moon, Hyun-Kyung),박주성(Park, Ju Sung),이용철(Lee, Yong Chul),신기영(Shin, Gi Young),조한빈(Jo, Han Bin),김복순(Kim, Bog Soon),김정헌(Kim, Jung Hun),채영주(Chae, Young Zoo) 한국영양학회 2013 Journal of Nutrition and Health Vol.46 No.1
The aims of this study were to estimate daily intake of macrominerals from beverages, liquid teas, and liquid coffees and to evaluate their potential health risks for Korean children and adolescents (1-to 19 years old). Assessment of dietary intake was conducted using the actual level of sodium, calcium, phosphorus, potassium, and magnesium in non-alcoholic beverages and (207 beverages, 19 liquid teas, and 24 liquid coffees) the food consumption amount drawn from “The Fourth Korea National Health and Nutrition Examination Survey (2007-2009)”. To estimate the dietary intake of nonalcoholic beverages, 6,082 children and adolescents (Scenario I) were compared with 1,704 non-alcoholic beverage consumption subjects among them (Scenario II). Calculation of the estimated daily intake of macrominerals was based on point estimates and probabilistic estimates. The values of probabilistic macromineral intake, which is a Monte-Carlo approach considering probabilistic density functions of variables, were presented using the probabilistic model. The level of safety for macrominerals was evaluated by comparison with population nutrient intake goal (Goal, 2.0 g/day) for sodium, tolerable upper intake level (UL) for calcium (2,500 mg/day) and phosphorus (3,000-3,500 mg/day) set by the Korean Nutrition Society (Dietary Reference Intakes for Koreans, KDRI). For total children and adolescents (Scenario I), mean daily intake of sodium, calcium, phosphorus, potassium, and magnesium estimated by probabilistic estimates using Monte Carlo simulation was, respectively, 7.93, 10.92, 6.73, 23.41, and 1.11, and 95th percentile daily intake of those was, respectively, 28.02, 44.86, 27.43, 98.14, and 3.87 mg/day. For consumers-only (Scenario II), mean daily intake of sodium, calcium, phosphorus, potassium, and magnesium estimated by probabilistic estimates using Monte Carlo simulation was, respectively, 19.10, 25.77, 15.83, 56.56, and 2.86 mg/day, and 95th percentile daily intake of those was, respectively, 62.67, 101.95, 62.09, 227.92, and 8.67 mg/day. For Scenarios I·II, sodium, calcium, and phosphorus did not have a mean an 95th percentile intake that met or exceeded the 5% of Goal and UL. (Korean J Nutr 2013; 46(1): 50 ~ 60)
Prostate Stem Cell Antigen in Gastric Adenoma and Cancer
김용수 ( Kim Yong Su ),송시영 ( Song Si Yeong ),문정 ( Mun Jeong ),김한수 ( Kim Han Su ),박승우 ( Park Seung U ),정재복 ( Jeong Jae Bog ),강진경 ( Kang Jin Gyeong ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> Prostate stem cell antigen (PSCA)는 123개의 아미노산으로 구성된 당화된 세포 표면 단백질로 Thy-1/Ly-6 세포 표면 항원과 유사성을 갖는 줄기 세포 항원이다. 전립선에서 처음 연구가 활발히 이루어졌으며 정상적으로는 전립선 선 세포에서 발현하고, 비정상적으로 전립선 암에서 과 발현하여 진행성 종양의 표지자로 쓰인다. 혈액 조혈을 담당하는 줄기 세포 및 전구 세포에서도 일시적으로 증가하는 것으로 알려져 있으며 정상
Simultaneous liver-kidney transplantation: A single-center experience in Korea
Minjae Kim,Shin Hwang,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Sung Shin,Young Hoon Kim,Hea-Seon Ha,Jung-Ja Hong,In-Ok Kim,Duck Jong Han,Sung-Gyu Lee 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.4
Backgrounds/Aims: Simultaneous liver and kidney transplantation (SLKT) has been established as the treatment of choice for patients with concurrent end‐stage liver and end‐stage kidney diseases. The objective of this study was to analyze the nationwide incidence of SLKT in Korea and the outcomes of SLKT in a high-volume transplant center. Methods: Databases of the Korean Network for Organ Sharing (KONOS) and Asan Medical Center from 2000 to 2019 were retrospectively reviewed to determine the incidence of SLKT. Results: During 20 years from 2000 to 2019, deceased donor SLKT was performed for 38 cases in the KONOS database. The proportion of deceased donor SLKT was 0.6% (20 of 3333) before adoption of MELD score, which was significantly increased to 1.2% (18 of 1524) after the adoption of MELD score (p=0.034). In our institution, there were 11 cases of SLKT (2 cases with deceased donors and 9 cases with living donors). SLKT accounted for 0.2% (11 of 6468) of total liver transplantation volume. During follow-up, five patients died due to hepatocellular carcinoma recurrence (n=2), infection (n=2), or unknown cause (n=1). The 1-year and 10-year overall patient survival rates were 90.9% and 81.8%, respectively. Conclusions: Results of this study revealed that the incidence of deceased donor SLKT was very low. An increase of such incidence is not anticipated unless the number of deceased donors is markedly increased. Currently, sequential living donor liver transplantation and kidney transplantation with deceased or living donors are mainstays of transplantation rather than SLKT in our institution.