최근 10년간 원광의대병원에서 시행한 소아 심장혈관 수술의 임상적 고찰

윤향석,정수미,최두영,오광수,오연균,김종덕,양현웅,이삼윤,김형곤,최종범,최순호,노병석 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

We reviewed 10 years experiences of the clinical aspects and early postoperative results in 544 pediatric patients(age less than 16 years old). Among them. 529 cases had the congenital heart diseases, and 15 had the acquired diseases. Open heart surgery was performed in 413 patients. 115 cases were treated with non-open heart surgery. 16 with interventional catheterization. Annual increase of the cardiac patients was not significant in recent 10 years, except slight increase in 1994. The mean age of the study patients had been evidently changed to younger year by year. Total mortality rate of the open heart surgery was 6.4%. The cyanotic congenital heart diseases were high in early postoperative mortality by 25.7%, whereas 4% in acyanotic group. The age group less than one month was most highest in surgical mortality(66.7%). There were no deaths in patients with patent ductus arteriosus(103 cases), atrial septal defect(83 cases) or pulmonary stenosis(17 cases). Among 220 patients with ventricular septal defects(VSD). 10(4.5%) were died early postoperatively. In cyanotic group, the patients with pulmonary atresia with ventricular septal defects(PAVSD), transposition of the great arteries(TGA), interrupted aortic arch(IAA), complex cardiac anomalies with isomerism seemed to be most susceptible to an early death.

원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

심리적 임파워먼트의 선행요인과 결과요인에 관한 연구

오종석,김종관,이용탁 釜山大學校 商科大學 2002 釜山商大論集 Vol.73 No.-

The purpose of this research is to examine the antecedents and outcomes of psychological empowerment. Focusing on the psychological experience of empowerment, we first examined the relationship between antecedents and the four dimensions(meaning, competence, self-determination, impact) of psychological empowerment. Second, we examined the impact of psychological empowerment on the job satisfaction and job related strain. This empirical results are as follows. First, individuals who perceive that have a high degree of self-esteem, internal of locus of control report a high level of psychological empowerment. And individuals who perceive that have a high degree of role ambiguity in their work report a lower level of psychological empowerment. Second, individuals who perceive that have a high degree of sociopolitical support, access to information, access to resources, participate work climate in their organization report a high level of psychological determinant, impact dimensions in psychological empowerment. But, competence is not significantly influence on the job satisfaction. Finally, all dimensions of psychological empowerment are not significantly impact on the job related strain. As the results, psychological empowerment is associated with in the feeling of job satisfaction, and is recognized as one means by which organizations can effectively manage management innovations.

釜山地域 經濟發展을 위한 地域企業人의 役割과 責任 : 企業家精神과 地域的 責任을 中心으로

오종석,황한식,김종관 부산대학교 1995 地域經濟硏究 Vol.- No.4

한국경제는 지금까지 국가 중심적 경제체제를 유지해 왔으나, 세계화, 지방화라는 시대적 변화에 직면하여 지역 분권적 경제체제를 확립하고, 이를 통해서 지역경쟁력을 강화함으로서 지역중심의 세계화를 추진해 나가지 않을 수 없게 되었다. 따라서 본 연구는 효과적인 지역경제발전을 모색해 나가기 위해서 부산지역을 연구대상으로 하여, 지역경제발전의 주체와 지역경제발전의 원동력을 조명하고, 지역경제발전을 위해서는 어떠한 환경이 조성되어야 하는 지를 문헌연구와 실증연구를 토대로 하여 고찰해 보고자 하였다. 그 결과, 다음과 같은 결론을 도출할 수 있었다. 첫째, 세계화, 지방화 시대의 지역경제 발전전략은 자립적·내발적 이어야 하며, 지역 스스로가 발전주체가 되어야 한다는 점이다. 특히 지역기업인은 지역에서 가장 중심적인 역할을 담담해야 하며, 지역기업 중심의 지역주체성 확립이 지역경제 발전의 기반이 되어야 한다는 것이다. 둘째, 지역경제 발전의 원동력은 지역기업인의 기업가정신과 지역적 책임이며, 이것을 통해 기업의 내생력을 강화시켜서 기업발전을 이룩하고, 지역경제의 발전을 실현해 나가야 한다는 점이다. 셋째, 지역경제의 발전을 위해서는 지역경제의 낙후원인을 분석, 진단하고 이를 통해서 외생적 환경조건을 정비함으로써 지역경제의 발전을 도모해 나가야 한다는 것이다.

Fusobacterium nucleatum의 유황화합물 생성에 영향을 미치는 인자

오인근,박은혜,양규호,오종석 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.1

Fusobacterium nucleatum, one of the bacteria causing halitosis, produces the volatile sulfur compounds (VSC) such as H2S in the media containing sulfur components, and forms FeS by binding with iron component. The various factors of oral cavity affect the concentration of sulfur compounds produced by Fusobacterium nucleatum. In this study, the effect of nutrients and pH on the production of sulfur compounds by Fusobacterium nucleatum was studied with the following results; 1. The optical density of broth was increased to 0.817±0.032 and 1.297±0.024 by adding 1.0% sodium thiosulfate and 0.05% L-cysteine hydrochloride in the media, respectively. 2. Though the optical density of broth was 0.799 ± 0.032 by adding volatile sulfur compounds (VSC) only in the media, it was increased to 1.775±0.003 and 1.648±0.022 by adding xylitol combined with glucose and fructose, respectively. 3. The concentration of VSC was above 20,000 ppb in the media above pH 5.5. The optical density of broth was still high in the media with L-cysteine hydrochloride of higher concentration, being low in the media of lower pH. 4. The concentration of VSC was high when there was distilled water or saline solution on the media, and their amount was small. These results suggest that the production of sulfur compounds by Fusobacterium nucleatum is inhibited by xylitol and acid.

해조류에서 추출한 SCH-T3의 elastase 억제

오경석,박영립,이종석,황규왕,염윤기 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & Objective: Upon UV irradiation of skin, matrix metalloproteinases are induced and then degrade collagen and elastin which provide the structural integrity of skin. The purpose of this study is to investigate the inhibition of elastase by SCH-T3 extracted from marine plants. Method: From gathered seaweeds, which are Laminariacea and Alariaceae in Phaeophyta, In Korea water, 21 materials were extracted. To determine the optimal condition for the extraction of SCH-T3, the yields of SCH-T3 was measured compared at various solvents, concentrations, and extraction time. Finally, the inhibitory effect of SCH-T3 on elastase was measured under various conentrations of SCH-T3. Results: Among 21 extracts, SCH-T3 had excellent elastase inhibitory effect. The yields of SCH-T3 was highest with the use of 60% and 70% ethanol as sovents, at 12 hours extraction, and with increasing temperature. Conclusion: These results suggest that SCH-T3, extracted from marine plants, has an inhibitory effect on elastase in vitro and may be used in prevention and treatment of photoaging in the future.

유산구균 1370의 수용성 글루캔 형성에 영향을 미치는 인자

오인근,양규호,정진,오종석 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

Streptococcus mutans가 치태를 형성할 때, 유산구균 1370(Lactococcus lactis 1370)이 생산하는 수용성 글루캔이 영향을 미친다. 본 연구에서는 여러 인자에 의한 수용성 글루캔 형성 정도를 유산구균 1370 배양 상청액의 흡광도로 측정하여 다음과 같은 결과를 얻었다. 1. 5% 자당이 첨가된 M17 broth에서 유산구균 1370 배양 상청액의 흡광도는 높고 Streptococcus mutans 배양 상청액의 흡광도는 낮았으나, 통계학적인 유의성은 없었다. 2. M17 broth에 10% 자당을 첨가하여 유산구균 1370을 배양할시 배양 상청액의 흡광도는 첨가하지 않을 때보다 높았다(p〈0.05). 배지 pH가 5에서보다 7에서 배양 상청액의 흡광도가 더 높았다(p〈0.05). 3. 32℃, 37℃, 42℃중 37℃에서 배양시 배양 상청액의 흡광도가 가장 높았으나 통계학적인 유의성이 없었고, 호기성 배양시보다 혐기성 배양시 배양 상청액의 흡광도가 더 높았다(p〈0.05). 4. 배지의 CaCl₂농도가 1.0mM에서 (p〈0.05), KCl 농도가 2.5mM에서 (p〈0.05) 배양 상청액의 흡광도가 높았다. 5. M17 broth에 5% 자당을 첨가한 배지에 유산구균 1370을 접종하여 배양한 배양 상청액의 배지를 1:3으로 가한 비커와이어 검사에서 Streptococcus mutans에 의하여 형성된 인공치태 무게는 5.6mg으로 5% 자당을 첨가하지 않을 때의 103.0mg에 비교하여 현저히 감소하였다 (p〈0.05). 이상의 결과를 요약하면 유산구균 1370에 의한 수용성 글루캔의 형성은 자당이 함유된 배지나 세균 증식이 잘 되는 조건에서 증가하였으며, 수용성 글루캔이 Streptococcus mutans에 의한 인공치태 형성을 억제하였다.

치태형성 억제세균의 분리

오종석,박진경,양규호,정진 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.3

치태의 주요성분인 비수용성 글루캔의 형성을 억제시키는 세균을 분리하기 위하여 유치원 원아 만여명으로 부터 타액을 채취하였다.일회용 큐벧을 사용하여 비수용성 글루캔의 형성을 억제시킨 세균을 분리하였다.분리된 세균을 그람 염색과 API 20S kit 와 API 50 CHL kit를 사용하여 당발효 및 생화확적 특성을 검사한 결과,Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis로 동정되었다.비수용성 글루캔 형성 억제 정도를 판정하기 위하여 일회용 큐벧에서 S.mutans 단독 배양시에는 550nm에서의 흡광도가 1.503이었으나,S.mutans 와 Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis, Lactobacillus acidophilus 혼합 배양시에는 각각의 흡광도가 0.823,0.912,0.894,0.878,0.753,0.845,1.021로 감소되었다. The insoluble glucan is the major substance of dental plaque. In order to isolate the bacteria inhibiting the formation of insoluble glucan in disposable cuvette,saliva was got from about 10 thousand children.The isolated bacteria were tested by API 20S kit and API 50 CHL kit.These bacteria were identified as Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis,and Lactobacillus acidophilus.When Streptococcus mutans was cultured with Streptococcus oralis,Streptococcus mitis,Streptococcus mitior,Streptococcus sanguis,Enterococcus durans,Lactobacillus lactis,and Lactobacillus acidophilus in disposable cuvette,the optical density at 550 nm was 0.823,0.912,0.894,0.878,0.753,0.845,1.021 respectively,while being 1.503 in the disposable cuvette Streptococcus mutans only.

알코올 섭취 후 운동이 시간 경과에 따른 혈중 알코올 농도와 간 기능 효소에 미치는 영향

오명진,김종오,윤재석,정일규 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

This study was done in order to investigate the effects of performing the light exercise right after alcohol drinking on the changes of blood alcohol and ALT, AST concentration, All seven healthy collegiate students volunteered to two sections of experiment, Each subject drank one bottle of Soju(360ml, 75.6g ethanol) For forty minutes at the same speed of drinking with the same kind and volume of carbohydrate snacks. Each section of the study was conducted by a two-cross-over design with four days wash-out period, All volunteers performed brisk walking exercise corresponding to about 50-60%HRmax of exercise intensity For 30minutes immediately after alcohol drinking. Blood sampling was conducted by drawing about 10ml venous blood from antecubital vein at pre -alcohol drinking, and post- 1, 2, 4 hour alcohol drinking. Blood alcohol concentration reduced significantly at all time course in exercise group compared to Control group. However, the concentration of serum aspartate aminotransferase and alanine aminotransferase, the indicator of liver cell damage, showed no significant difference between two groups. In conclusion, performing light exercise such as brisk walking after alcohol drinking may somewhat help to reduce the concentration of blood alcohol Faster by influencing the alcohol metabolism.

현행 고등학교 화학 교과서 비교 연구

오제직,최석남,이종길 공주대학교 사범대학 과학교육연구소 1994 과학교육연구 Vol.25 No.1

This paper aims to help the teachers select the textbook and provide them with the basic teaching materials as an ideal model by analyzing the organization (its element and appropriateness), volume amount, experiment matter, and the contents of the highschool chemistry textbooks, which have been revised in accordance with the 5th amended curriculum. The results of the analogy are as follow 1. Organization (its element and appropriateness) : Though having some distincitive characteristics, all the textbooks have almost the same introduction, development, summary, and further study, which are appropriate for the textbook model. 2. The volume amount: All the textbooks have almost the same frame, but s a big difference in such things as the number of pages, of pictures and charts, of Gothic terminology, and relative importance of each chapter. And all the materials such as pictures and photos are black-and-white, which we think are less helpful to the students` study. 3. The experiment matter: There`s a geat difference in the number, kinds, ratio contents and subject of experiment in each chapter. And there are some distinctive characteristics in the type, level, method, and investigative skills of the experiments. 4. The contents : There are considerable differences in the additional and reduced sections. Therefore, which book is selected is very important, and the teachers should not skip any class-work.