도로 종류별 안전도에 관한 연구 : 고속도로와 국도를 중심으로 Focussing the express highway and the national road

윤정길,홍창의,김만배 건국대학교 사회과학연구소 2000 社會科學論叢 Vol.24 No.-

The paper aims to compare the safety between highway and the national road in South Korea. I first of all,we will try to evaluate the accident rates by VEK(vehicle kilometers traveled) for the express highway and for the national road.All things being equal,each accident rate will tell which road is more safe. For the result of this paper, the accident rate, fatal rate, inury rate of the national road are respectively 4.5 times,2.0 times,3 times as hogh as that of express highway. In conclusion, the express highway is more safe than the national road though our method.

交通安全施設 投資政策에 關한 硏究

尹正吉,洪昌義,金萬培 建國大學校 社會科學硏究所 1997 社會科學論叢 Vol.2 No.-

■Background and purpose Traffic safety facilities is an important tool that it is contribute to traffic flow and safety instead of the roles of a traffic police or maneger in road. The current system for road traffic safety related facilities management is not in a satisfactory state, and more efficient system, therefore, is needed for the policy makers, researchers, and other people. This paper is to analyze the problem in the current system and to make suggestion to establish more efficient system. ■Contents · Analysis of the present road traffic safety facilities management system. - Functional allocation, financial resources, and future demand cost forecast · Case study in Japan. - Comparative analysis between Korea and Japan · Development of road traffic safety facilities management system. - Principles and alternatives for financial resources and functional allocation between central and local government ■Conclusions Traffic safety facilities should be maintained in the current system, in order to enhance operational capacity, secured proffessional manpower and utilized the third sector or RTSA(Road Traffic Safety Association). Also the future traffci safety facilities investment cost is to forecasted 3,400 hundred million won in the 2000 year, therefore is needed financial resources in centural government. In order to secure investment resources for traffic safety facilities should be given improvement plan of special account law

Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun‐,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

<P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

경계요소법에 의한 이종재료 접합 잔류열응력의 해석

유영철,이 원,윤인식,정의섭 韓國非破壞檢査學會 1995 한국비파괴검사학회지 Vol.15 No.4

전자 부품의 일종인 LSI 패키지의 제조 과정에서 절연·방진·방습 등을 목적으로 수지 몰딩이 널리 사용되고 있는데, 냉각과정에서 금속과 수지의 계면에 접합 잔류열응력이 발생하여 파괴의 원인이 되고 있다. 접합 잔류열응력의 측정에는 X선 회절법등이 사용되지만 측정상의 어려움과 계면단 응력특이성에 대한 해석의 곤란함 때문에 적절한 모델링에 따른 수치해석적 연구가 새로이 주목을 받고 있다. 본 연구에서는 Al/Epoxy를 몰딩 접합한 세가지의 대표적인 계면 형상을 선정하여 계면에서의 잔류열응력을 경계요소 수치 해석 및 스트레인 게이지를 이용한 실험을 통하여 각각 해석하였다. 수치해석과 실험결과는 정상적으로 잘 일치하였으며, 서브 요소를 사용하므로써 계면단 응력 특이성의 해석 정밀도를 향상시킬 수 있었다. 또한 접합 잔류열응력의 해석결과로부터 수직응력에 의한 계면 박리가 예상되고, 피착체의 두께가 증가할수록 응력 특이성이 강하게 나타남을 확인하였다. In general residual stress is measured by X-ray diffraction method but in case of bonding residual thermal stress it is inadequate technique to examine the stress singularity. Therefore Two-dimensional elastic boundary element analyses were carried out to investigate the residual thermal stress and stress singularity of bonding interface in Al/Epoxy. This boundary element results were compared with the strain gauge measurements. The effects of different interface models, sub-elements and adherend thickness are presented and discussed. On the basis of the obtained results, interface delamination causing by normal stress is expected and stress singularity is observed more intensively increasing with adherend thickness. It is concluded that the bonding strength of Al/Epoxy interface can be estimated correctly by taking into account the stress singularity at the edge of the interface.

[P508] Coexistence of lichen nitidus with lichen striatus

( Yun Sun Moon ),( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Lichen nitidus (LN) is an uncommon idiopathic inflammatory cutaneous eruption primarily of children. The dermatosis is composed of multiple, small, discrete, glistening, flesh-colored to slightly pink papules that may occur anywhere on the skin. LN has been argued to be a variant of lichen planus, yet the relationship of LN and lichen striatus (LS) has been largely neglected. However, there are several case reports of showing typical histologic features of LN (a claw clutching a ball configuration of the epidermis) and histologic features of LS (periappendageal infiltration) simultaneously. Furthermore, there are cases of LN presenting in a linear distribution, clinically mimicking LS. We herein report a case of coexistence of LN with LS. A 3-year-old girl presented with a month history of diffuse purpuric linear patches on feet and both legs, as well as multiple skin colored to pinkish tiny papules on back area. On the basis of the clinical course, the lesions on the patient`s legs were diagnosed as LS, whereas the lesions on back were diagnosed as LN. Thus, LN and LS could represent different, but closely related diseases with possible similar etiologic factors. Our case should motivate further investigation of the relationship of LN and LS.

A Survey of Ticks (Acari: Ixodidae) and Severe Fever with Thrombocytopenia Syndrome Virus Infection in Korea National Parks in 2013-2014

Jeong Byoung Chae,Yun Kyung Cho,Sung Suck Oh,Jong Chul Jeong,Eui Jeong Hong,Hee Young Chae,Joon Seok Chae 대한수의학회 2015 대한수의학회 학술대회발표집 Vol.2015 No.-

The effect of citrinin extracts in VEGF-mediated angiogenesis in dermal endothelial cell

( Yun Sun Moon ),( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Do Seon Jeong ),( Sang Min Lee ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Cutaneous carcinogenesis is a multistep process in which clinically recognizable pre-stages occasionally occur. The importance of angiogenesis in tumor progression has been highlighted by studies showing that the angiogenic potential of tumors developed skin. Objectives: In the present study, we investigated the antiangiogenic activities of citrinin present in red yeast rice, widely used in Asia as a food additive in both in skin tumor and in vitro study with human vascular endothelial cell. Methods: We assessed angiogenesis in skin epithelial cell tumor specimens(64 specimens from 54 patients) in progressing step actinic keratosis, squamous cell carcinoma in situ, and squamous cell carcinoma by evaluated with microvessel density(MVD) and the expression of vascular endothelial growth factor(VEGF) . We evaluated the effect of citrinin to angiogenic activity to human vascular endothelial cell treated to angiogenic promoter VEGF. Results: The vascular density and expression of VEGF more increased squamous cell carcinoma than actinic keratosis in full thickness of epithelial layer and dermal vascular structure. The result presented that citrinin has antiangiogenic effect to VEGF induced angiogenesis in dose dependent manner might be the prevalent and immediate therapeutic mechanism of the progression of tumorigenesis. Conclusion: This study provides useful data on the topical therapeutic modality include citrinin to precancerous lesion progress to skin cancer.

[P336] Generalized cutaneous angiosarcoma associated with multiple myeloma

( Jeong Won Jo ),( Young Bin Shin ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Cutaneous angiosarcoma is a rare, malignant, vascular neoplasm of the skin commonly diagnosed in the head and neck regions. It arises infrequently in the lower extremity. In most cases, the exact etiology of cutaneous angiosarcoma is unclear. Recently, gene amplifications, especially MYC gene, have been identified as a new etiopathogenesis of angiosarcoma. MYC amplification may induce aberrant angiogenic phenotypes allowing the onset of the malignancy. Meanwhile, in multiple myeloma, MYC is activated and contributes to the malignant phenotype. Therefore, there is a possibility that MYC gene might be the common cause of angiosarcoma and multiple myeloma. Herein, we present the rare case of cutaneous angiosarcoma on lower extremity accompanied by multiple myeloma. An 85-year-old woman visited our department with multiple brownish to black colored nodules with hyperkeratotic crust, which were 0.3 to 0.8 cm in diameter, on the both feet and toes. The excisional biopsy was performed and a diagnosis of cutaneous angiosarcoma was made. At the time of visit, anemia, azotemia, proteinuria and hematuria were found. Immunofixation electrophoresis and bone marrow were performed, so multiple myeloma was diagnosed. We suspected carefully that MYC gene might be the common cause of angiosarcoma and multiple myeloma.

P098 A clinical study on herpes zoster during the last 5-year-period (2011-2015)

( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Herpes zoster is a common dermatologic disease. But there has not been any report on the clinical characteristics of herpes zoster in the Province of Gyeongsangnam-do. Objectives: The purpose of this study was the elucidation of the clinical characteristics of herpes zoster in the Province of Gyeongsangnam-do. Methods: The study was conducted between 2011 and 2015 at our hospital outpatients. 901 patients with herpes zoster were evaluated in regard to age, sex, dermatomic distributions, associated diseases and complications. Results: Out of 901 cases, 396 were males and 505 were females. The maximum incidence was in the over 70 year-old group (26.4%). The most frequent involved dermatome was the trigeminal dermatome (28.7%). Associated diseases were observed in 679 patients (75.3%), which included hypertension (21.2%), malignancy (11.4%) and so on. Out of 901 patients, 443 (49.2%) developed complications. The most common complication was postherpetic neuralgia (27.1%). It is noteworthy that skin edema was accompanied from 43 patients (4.8%). Fourty patients showed edematous change on herpes zoster lesion. But other 3 patients showed facial edema in spite of involving herpes zoster in other area. Conclusion: Most of the results are similar to those previously reported, except for a higher incidence in trigeminal dermatome. The most interesting part of this study is herpes zoster can cause skin edema. We need to take further studies in future by others to explain causes in detail.