한국인 건선환자에서 발병하는 질환에 대한 연구 - 다기관 연구

김광호(Kwang Ho Kim),전현진(Hyun Jin Jeon),김광중(Kwang Joong Kim),윤재일(Jai Il Youn),김낙인(Nack In Kim),김태윤(Tae Yoon Kim),최지호(Jee Ho Choi),박기범(Ki Beom Park) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.7

N/A Background: The prevalence of other diseases associated with psoriasis has been investigated in recent years. Objective: This study was performed to see diseases associated with psoriasis in Korea. Methods: From September 1999 to May 2000, a total of 293 patients with psoriasis, who visited the department of dermatology in 6 hospitals, were enrolled in a subject group for the study. We surveyed the incidence rates of associated diseases. Results: In our study, diseases more concomitantly present in patients with psoriasis were dermatophyte infection, seborrhea dermatitis and benign tumor & nevus in skin diseases and obesity, diabetes mellitus, hypertension, gastritis and hepatitis in systemic diseases. Less concomitantly present in-patients with psoriasis were erythroderma, acne, contact dermatitis, atomic dermatitis, bacterial infection, tonsillitis, and internal cancer. Conclusion: Our observations show a distinct pattern of diseases associated with psoriasis in Korea. Further investigation will be mandatory to elucidate concomitant diseases in psoriasis. (Korean J Dermatol 2001;39 (7): 743~748)

IN-1130, a Novel Anti-metastatic Agent in MMTV/c-Neu Mice, was Tested for the Toxicity and Metabolism in vitro and in vivo

Yeo Woon KIM,Ji Hye KIM,Seo Youn GO,Jung In JEE,Yong Kook KIM,Kyung Nan MIN,Dae-Kee KIM,Yhun Yhong SHEEN 환경독성보건학회 2006 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases

Jha, Mithilesh Kumar,Kim, Jong-Heon,Song, Gyun Jee,Lee, Won-Ha,Lee, In-Kyu,Lee, Ho-Won,An, Seong Soo A.,Kim, SangYun,Suk, Kyoungho Elsevier 2018 Progress in neurobiology Vol.162 No.-

<P><B>Abstract</B></P> <P>Astrocytes, which are homeostatic cells of the central nervous system (CNS), display remarkable heterogeneity in their morphology and function. Besides their physical and metabolic support to neurons, astrocytes modulate the blood-brain barrier, regulate CNS synaptogenesis, guide axon pathfinding, maintain brain homeostasis, affect neuronal development and plasticity, and contribute to diverse neuropathologies via secreted proteins. The identification of astrocytic proteome and secretome profiles has provided new insights into the maintenance of neuronal health and survival, the pathogenesis of brain injury, and neurodegeneration. Recent advances in proteomics research have provided an excellent catalog of astrocyte-secreted proteins. This review categorizes astrocyte-secreted proteins and discusses evidence that astrocytes play a crucial role in neuronal activity and brain function. An in-depth understanding of astrocyte-secreted proteins and their pathways is pivotal for the development of novel strategies for restoring brain homeostasis, limiting brain injury/inflammation, counteracting neurodegeneration, and obtaining functional recovery.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Astrocytes are important regulators of brain functions, and crucial functions are executed via astrocyte-secreted proteins. </LI> <LI> Astrocyte-secreted proteins play key roles in physiological processes and execute both detrimental and beneficial actions in CNS disorders. </LI> <LI> Understanding the many functions of astrocyte-secreted proteins under specific spatiotemporal conditions may lead to major advancements in astrocyte biology. </LI> <LI> Functional dissection of astrocyte-secreted proteins can facilitate the development of novel diagnostic and therapeutic strategies for neurological disorders. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

체육계열 전공 대학생의 필라테스 경험과 인식 변화에 대한 현상학적 연구

김지혜(Kim, Ji-Hye),윤지인(Yoon, Jee-In),박승순(Park, Seoung-Soon) 한국체육과학회 2021 한국체육과학회지 Vol.30 No.3

The purpose of this study is to explore the meaning and value of pilates experience for the college students majoring in sport. Also, we compared the awareness on pilates before and after student participation. Using phenomenological research methods, authors conducted in-depth interviews with 10 college students majoring in sport. Regarding the research question 1, the most important meanings and values of pilates participation that students found were a) experiencing frustration while participating in pilates, b) understanding my body movement, c) the increased interest in body alignment, and d) building teaching skills through pilates. For the second research question, we tried to compare the awareness on pilates before and after the participation. The participants treat pilates as less-approachable genre because of high-cost. However, after they grasp the basics of pilates through participation, they recognized that pilates is actually an approachable sports. In addition, before the participation, students did not hesitate to link pilates with celebrities, it was consider as something to do with flexibility. However, after they experienced the exercise, participants realized that it is more about training their muscles. With more insights on the perception of pilates experience for college students majoring in sport, it is possible to make a better curriculum for those who are interested in this exercise.

대학생 운동선수의 역할 정체성 갈등에 관한 탐색

윤지인(Yoon, Jee-In),박승하(Park, Seung-Ha),김효미(Kim, Hyo-Mi) 한국체육과학회 2015 한국체육과학회지 Vol.24 No.5

The purpose of this study was to explore the identity conflict among winter sports student athletes. This study used a phenomenological framework to explore the research questions. A total of 6 female winter sports student athletes participated in the individual in-depth interview with one of the authors. First, whereas college student athletes have identified positive aspects of adapting a student identity, they admitted that they have been struggling with problems while they acquire the new identity. Second, this study found that there can be two different types of multiple role identity conflict. The first dimension we found was the identity conflict in between ‘student’ and ‘athlete.’ The other conflict was related to the identity confusion between the role as a family member (e.g., inside the home) and as a person participating in athletic competition (e.g., in training). In conclusion, while winter sports student athletes faced with problems in college life, they have identified positiveness of being a college student athlete. Also, we found that they also have multi role identity conflict as a student, an athlete, and a family member. More research is needed to gain information about how student athletes perceive their different roles in life and how we better accommodate their situation.

Comparison of the Ingredient Quantities, and Antioxidant and Anti-inflammatory Activities of Hwangryunhaedok Decoction Pharmacopuncture by Preparation Type

이진호,Min Jeong Kim,Jae Woong Lee,Me Riong Kim,In Hee Lee,Eun Jee Kim 대한침구의학회 2014 대한침구의학회지 Vol.31 No.4

Objectives : The main aim of this study was to assess the comparative efficiency of two preparation types of Hwangryunhaedok decoction(HRHD-D) using distilled and mixed extraction by measuring the index components and indicators of antioxidant and anti-inflammatory effects. Methods : The antioxidant activity was assessed by comparing distilled and mixed extractions of HRHD-D using an ELISA reader. The anti-inflammatory effect was determined by measuring NO amounts in RAW 264.7 cells. The contents were analyzed with high performance liquid chromatography-diode array detector(HPLC-DAD). Results : The electron donating ability of mixed and distilled extractions obtained with 500 ppm DPPH(1,1-diphenyl-2-picrylhydrazyl assay) solution were 57.8 % and 4.2 %, respectively. The total phenolic content of mixed extraction was 6.9 times that of distilled extraction and total flavonoid content was 51.5 times higher. The anti-inflammatory effect was assessed by NO measurement, and was found to increase significantly dependent on concentration in all mixed extract concentrations(25, 50, 100, 200, 400 μg/mL), but the difference in distilled extraction by concentration was only significant at 200 and 400 μg/mL. The HPLC analysis results of mixed extract of HRHD-D showed detection of all four main active constituents of HRHD-D. However, they were not detected in the distilled extract of HRHD-D. Conclusions : Mixed extraction with distillation added to decoction of HRHD-D showed better efficacy in antioxidant and anti-inflammatory effects, and ingredient quantities compared to distilled extraction. Further stability and clinical efficacy studies for standardization of mixed extractions are required.

원발성 위장관 임파종의 임상적 고찰

윤진우,한지숙,고윤웅,박인서,최응재,주승행,김태승 大韓血液學會 1983 大韓血液學會誌 Vol.18 No.2

하지 절단자 보행의 운동역학적 분석

임규찬,박윤서,배성제,정철수,신인식,김복영 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the gait pattern in an amputee for the purpose of improving the proper gait posture and designing the prosthetic. The subjects were six males amputees and one normal person. The ground reaction force was measured using AMTI force platform. The conclusions were as follows; 1. In case of amputee group, the ground reaction force was revealed in specific figure according to position in which they used the prosthetic, whereas in case of normal person the ground reaction force was revealed in the figure of two humps in regard of vertical axis. 2. In case of amputee group, the ground reaction force in time between fight foot contact and left foot contact was deviated from a figure of rectangle, whereas in case of normal person the ground reaction force was revealed in the figure of rectangle. 3. In case of amputee group, the ground reaction force referred to both feet angle point of view was revealed in irregular figure, whereas in case of normal person the ground reaction force was revealed about 47。

미세절편체에 의한 절화류의 기내증식

이지영,이승우,김용구,정인식,설일환 慶熙大學校 1997 論文集 Vol.26 No.-

Experiments were conducted to find out the optimum cultural conditions for micro-cross sectioned leaf segments of Gypsuphila paniculata L. Gerbera hybrida and Dianthus caryophyllus. Survival percentages of micro-cross sectioned segments were the highest in gypsophila, followed by carnation. Gerbera showed on survived segments. In gypsophila, segments thicker than 400㎛ were required to obtain over 75% survival. The percentage of adventitious bud formation was much higher with 600㎛ segment as compared with 400㎛. The regeneration of micro-cross sectioned segments of gypsophila was not sensitively affected by the auxins at varying concentrations. The elongation of adventitious shoot was promoted by kinetin compared with BA. In segments of 600㎛ thickness, adventitious shoot formation was promoted by BA compared with kinetin Adventitious shoot formation or shoot growth was not affected by KNO_3 concentrations with the segments of 400㎛ thickness. But adventitious shoot elongation was promoted significantly with segments in 600㎛ thickness. KH_2PO_4 (170 mg/1, standard concentration of MS medium) was effective for adventitious shoot formation. MgSO_4 also promoted adventitious shoot formation myo-Inositol tended to be suppressed regeneration of gypsophila.

복수과 진료 환자의 중복 처방에 대한 분석 및 평가

이지은,장혜경,오지영,유윤경,김현지,임숙인,연숙희,강진숙,최귀령 한국병원약사회 2003 병원약사회지 Vol.20 No.1

In an aging society, there is an increasing possibility of the duplication of the drugs given to patients because they take many kinds of drugs. Among the prescriptions given to the patients who was treated at multiple ambulatory clinics in St. Mary's hospital for one month of September, 2002, in which drugs that has identical or similar effects are prescribed, we analysed and evaluated them by patients' characteristics, kinds of medication, severity of side effects on a case by case basis. More, we assessed the potential additional costs. As a result of this study, the duplication rate turned out to be 6.69% and it was shown that the proportion of the elderly patients over 60 was high. The gastro-intestinal medications took up a large part and most of the cases showed that the danger caused by double taking of medicine was slight, but there were some examples in which the serious side effects were predicted. Expected additional costs were the average 11.349 won and it ranges from the minimum of 56 won to the maximum of 135,720 won. In conclusion, the management of drug histories of the patients who need the plural treatments is very important and the necessity of the individual and professional guidance of taking medicines for the elderly patients is emerged, too.