모 제약회사 근로자들의 직업성 천식 유병률과 약제 분말 노출수준

오성수,최용휴,김은아,이영목,장재길,유장진,박승현,김태균,정수영,김규상,강성규 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 제약회사에서 직업상 천식의 유병 규모를 파악하고 작업공정에 대한 작업환경 측정을 통해 제약회사의 약제 분말에 대한 노출수준을 평가하고자 하였다. 방법: 제약회사에서 약제 분말에 노출되는 근로자를 대상으로 천식을 선별하기 위하여 설문조사 및 진찰, 혈액검사, 폐기능 검사 그리고 피부단자시험을 실시하였고, 각 부서별 공정에 따라서 총분진과 항생제 또는 효소제 분말에 대한 작업환경 측정을 실시하였다. 직업상 천식이 의심되는 근로자에 대하여 기관지과민성에 대한 검사(메타콜린을 이용한 비특이 기관지유발시험)와 약제 분말 기관지유발시험을 실시하여 확진하였다. 결과: 설문조사 및 진찰에서 작업 관련 천식 증상이 있는 근로자는 11명(34.4%)이었고, 약제 분말을 이용한 피부단자시험에서 1+ 이상 반응을 보인 근로자 10명(31.2%)이었다. 비특이 기관지유발시험 결과 8명(25.0%)이 양성(PC20 ≤16 mg/ml)이었다. 약제 분말 기관지유발시험을 통해 직업상 천식으로 확진된 근로자는 5명(15.6%)이었다. 작업환경 측정에서 원료를 충진하거나 투입하는 작업 그리고 정립작업에서 약제 분말에 대한 노출이 많았다. 결론: 제약회사에서 직업상 천식은 주로 제조공정 중 약제 분말에 노출된 근로자에서 발생하여, 증상 및 직업성 천식의 유병률이 높았다. 따라서 원료를 충진 또는 투입하는 작업과 정립작업 등 제조과적에서 약제 분말 노출을 줄이기 위한 세심한 주의가 필요하여, 약제 분말을 취급하는 근로자에 대해서는 천식 증상 조사뿐 아니라 정기적으로 피부단자시험, 비특이 기관지유발시험 등을 실시하여야 할 것이다. Objectives: After the investigation of one worker with occupational asthma, we surveyed the preva- lence of occupational asthma and the exposure level of pharmaceutical dust of 32 workers in a pharmaceutical company. Methods: Thirty-two of the 90 employees participated in the survey which consisted of questionnaire, blood sampling, spirometry and skin prick tests with 8 common allergens as well as 9 antibiotics and 2 enzymes. Various indices of the working environment were also measured. Subjects who had a symptom suggestive of work-related asthma or positive skin prick test were further investigated by PC20 methacholine. Nine subjects who had a PC20 result of 16 mg/ml or less (n=7) or had work-related symptoms and positive skin prick test (n=2) were referred to undergo a specific bronchial provocation test to phar- maceutical dust in an academic allergic disease center. Results: Eleven of 32 workers (34.4%) had a work-related symptom suggestive of occupational asthma. Ten (31.2%) showed positive skin prick test. 8 (25.0%) had a PC20 result of 16 mg/ml or less (indicative of significant bronchial hyperresponsiveness), and 5 (15.6%) had a positive result on the specific bronchial provocation test. Exposure levels of stuffing, input of raw materials and screening process were relatively high. Conclusions: This survey showed that pharmaceutical workers have an increased risk of occupational asthma. Although pharmaceutical factories maintain a relatively good working environment, careful control of respiratory tract exposures, especially during stuffing, input or raw materials and screening process, is important to prevent occupational asthma. Pharmaceutical workers need to undergo regular skin prick and methacholine bronchial provocation tests, as well as asthmatic symptom survey, to ensure the early detection and prevention of occupational asthma.

국내 시판 고령친화식품의 품질특성

장미순 ( Mi-soon Jang ),김풍호 ( Poong-ho Kim ),오재영 ( Jae-young Oh ),박선영 ( Sun Young Park ),김예율 ( Ye Youl Kim ),강상인 ( Sang In Kang ),김진수 ( Jin-soo Kim ) 한국수산과학회(구 한국수산학회) 2021 한국수산과학회지 Vol.54 No.3

As the aging population of the world grows, senior-friendly foods are becoming increasingly popular. In this study, the quality characteristics of domestic commercial senior-friendly foods were investigated and compared to the standard specifications of the Food Code and KS H4897. Herein, 18 samples of domestic commercial senior-friendly foods were utilized to analyze their appearance, physical properties (hardness and viscosity), nutritional value (protein, vitamin, mineral and dietary fiber), digestion rate, and hygiene indicator bacteria. When compared to the hardness standards of the Food Code all 18 samples were found to be satisfactory; however, when compared to the nutritional standard (at least three types of nutrients must be above the minimum), only five products, HG-7, DW-1, PS-1, OH-1 and OH-2, were found to be satisfactory. In addition, when the 18 samples were compared to the Korean Industrial Standard (2020), all 18 products were found to be satisfactory for physical properties and hygiene standards; furthermore, all samples, excluding HB-2, were suitable for nutritional standards (at least one type of nutrient must be above the standard).

Buffer/CoFe/Cu/Co 샌드위치 박막의 자기저항 특성

김희중,김미양,오미영,이장로,송은영,김경민 숙명여자대학교 자연과학연구소 1996 자연과학논문집 Vol.- No.7

DC magnetron sputtering방법으로 Corning glass 기판위에 버퍼층을 Fe와 ??로 바꾸어가면서 보자력이 다른 ??와 Co를 이용하여 buffer/CoFe(35Å)/Cu(tÅ)/Cu(35Å)의 형태로 샌드위치 박막을 제작하고 자기저항비의 버퍼층 두께 및 비자성층 Cu층 두께, 자성층 두께 의존성을 조사하였다. 자기저항비와 포화 자기장(??)은 버퍼층의 두께가 두꺼워짐에 따라 증대하다가 극대치 3%를 보인 후 완만하게 감소하였다. NiFe, Fe버퍼층을 갖는 시료를 비교한 경우, 각각 CoFe층과 Co층 사이의 결합 자기장(??)은 큰 차이가 없었으나 NiFe버퍼층을 갖는 시료가 minor자기저항 곡선의 반가폭 ??는 감소하고 자기저항(MR) slope와 관련된 field senditivity(%/Oe)는 향상되었다. Buffer(tÅ)/CoFe(35Å)/Cu(50Å)/Co(35Å) sandwiches prepared by dc magnetron sputtering on a corning glass substrate using ?? and Co possess different coercivities. Dependence of magnetoresistance on the type and thickness of buffer layer, thickness of Cu and thickness of magnetic layer in buffer/CoFe/Cu/Co sandwiches were investigated. Magnetoresistance ratio and saturation field ?? increased as the thickness of buffer layer becomes thicker, then decreased smoothly after maximum value. Improved field sensitivity was realized by the use of ?? buffer layer.

Ni-4.5%Al 피복강재의 마모특성

김귀식,오맹종,김성익,고장권 濟州大學校 産業技術硏究所 1997 산업기술연구소논문집 Vol.8 No.1

The pin-on-disk type wear testing machine was manufa tur dusing a personal computer. load cell and reduction motor. The tribological properties of Ni-4.5%Al coating steel by flame spray were investigated using this test machine. The experimental result has shown that the wear amount of coating steel was remarkably decreased than the S45C material. In the lubrication environment the wear amount was much less. The friction coefficient of S45C and coating material was respectively 0.4, 0.29 in the air, and it has respectively shown 0.18. 0.24 in the lublication. Increase of load didn't have effect on the change of the friction coefficient at all.

연속회분식공법을 이용한 염색폐수처리

김무식,최충식,이오석,전장표 대구보건대학 2002 대구보건대학 論文集 Vol.22 No.-

We investigated the basic operation conditions and biological properties for the dyeing wastewater treatment by sequencing batch reactor(SBR) process. The results are summarized as bellow. The experimental results were constructed with design factor. a. COD removal efficiency was appeared to be over 53% when carbohydrate not added to dyeing wastewater. According to carbohydrate addition weight COD removal efficiency was improved to 92%. b. TKN removal efficiency was appeared to be over 43% when carbohydrate not added to dyeing wastewater. When carbohydrate added to dyeing waste water TKN removal efficiency was achieved 87%. In a conclusion, therefore, under all the conditions provided in this study Sequencing Batch Reactor process appeared to be effective, economical and useful process for dyeing wastewater treatment.

영상광고 텍스트 읽기를 위한 교수·학습 방법론

김영순,오장근 경북대학교 사범대학부속 중등교육연구소 2003 중등교육연구 Vol.51 No.2

The aim of this study is to read TV-Ads, to propose its reading methodology, and to promote the educational creativity. In this study, TV-ads are regarded as creative texts in the process of creation, construction, producement, camera-work, and editing. In this respect, TV-ads are avaliable for the class of media literacy. Results of this study made the following teaching-learning model. First, teachers select and pick up the effective TV-ads for the lesson, design the teaching-learning plan, give to students the PPT-text thru mechanical media(personal computer, beam-projector, etc.) Second, students understand and interpret the mechanism of producing TV-ads, write the creative text, and its meaning can be communicated with others.

입원중인 환자들의 권리인식과 만족도

김선민,이태용,오장균,박암 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1

The author studied the recognition of patient's right and the degree of one's satisfaction to help set the index of doctor-patient relationship. The data was collected from 423 patients who were admitted to the hospital in Taejeon for fifteen days from Aug. 10, 1991 to Aug. 25, 1991. The results were as the follows: 1. The recognition of the patient's right and the degree of satisfaction were 4.46±0.734, 3.20±0.884 of total 5.0 score in each mean level. 2. "I believe a patient has a right to be treated equal.", "I believe a patient has a right to be compensated in medical accident." and "A patient should be told his diagnosis, treatment, prognosis about the disease by the doctor." were high mean level among each question. Their mean levels were 4.73, 4.69, 4.66 in sequence. 3. The recognition of patient's right by the age was the highest in teenager. It was lowest in above fifty years old. It was lower as age increase. There were statistically significant difference(P<0.05). The recognition of patient's right by the level of education was highest in college level and lowest in primary school level, but the degree of satisfaction was highest in primary school level and lowest in high school. The higher the education level was, the higher the recognition of patient's right was, but the lower it was, the higher the degree of satisfaction was. There was statistically significant difference(P<0.01). The recognition of patient's right be family income was highest in high income level but the degree of satisfaction was lowest. There was statistically significant difference in the recognition of patient's right(P<0.01). 4. Correlation between the recognition of patient's right and the degree of its satisfaction: "To be advised if the hospital proposes to engage in human experimentation affecting his care to patient one has the right to refuse to participate in such research projects was positive correlation with the degree of its satisfaction(r=0.1153). There was statistically significant difference(P<0.01). There were no correlation in other questions. 5. Correlation among each questions for the recognition of patient's right was highest between "…to expect that all communications and records pertaining to his care should be treated as confidential" and "…the right to know what hospital rules and regulations apply to his conduct as a patient"(r=.6314). 6. Correlation among each questions for the degree of satisfaction was highest between "…to considerate and respectful care" and "…to expect that within its capacity a hospital must make reasonable response to the request of a patient for services"(r=.6314).

高下島의 植物相과 植生에 關한 硏究

오장근,김진식 木浦大學校 沿岸環境硏究所 1995 沿岸環境硏究 Vol.12 No.1

Phytosociological investigation of the vegetation was carried out in Kohado island at the period of October 1996 by Braun-Blanquet's method. Vascular plants identified in these investigations were 95 families, 257 genera, 291 species, 52 varieties and 3 forma summing up to 346 species total. The forest vegetation was classified into 5 communities, Pinus thunbergii, Pennisetum alopecuroides, Erigeron canadensis, Phragmites communis, Suaeda japonica community. Based on the classification of communities the actual vegetation map was drawn in 1 : 50,000 scale.

Propylene Glycol Alginate 제조에 관한 연구

오찬열,김영조,강동섭,강영주,이장순 제주대학교 해양연구소 1988 해양자원연구소연구보고 Vol.12 No.-

TLD를 이용한 X-선 수중 흡수선량 측정 및 해석

오장진,전재식,하석호,김원식,황선태 대한방사선 방어학회 1988 방사선방어학회지 Vol.13 No.2

LiF : PTEE를 사용하여 중경 X-선(HVL : 0.29, 0.84, 1.60, 2.62mmCu)영역에 대한 수중 흡수선량을 측정 해석하였다. 이때 선량계(0.4mm × Φ12.5mm, hot-pressed LiF TLD-700)는 루사이트로 둘러 싸여 있고 물의 흡수선량은 각각의 TL출력 값에 Burlin의 공동이론을 적용하여 해석하였다. 그 결과 물 팬텀 속 깊이 5㎝에서 흡수선량률의 측정 오차는 최대 ±5%로 나타났다. 이 측정값을 측정 오차가 ±2%의 간접절대측정방법인 이온화법에 의한 측정값과 비교한 결과 두 값의 차이는 LiF : PTFE의 측정오차 범위 내에서 일치하였다. 이와 같은 결과로 LiF : PTFE를 이용한 수중 흡수선량 측정의 신뢰성을 확인할 수 있게 되었으며 이는 중경 X-선 영역에 대한 선량당량 평가의 근거로 활용 될 수 있을 것이다. Absorbed dose in water was analyzed by Burlin's general cavity theory for medium X-ray energy region (HVL : 0.29, 0.84, 1.60, 2.62mm Cu) using LiF : PTFE TL dosimeter(0.4mm x Φ 12.5mm, hot-pressed LiF TLD-700) which was enclosed in Lucite capsule. The absorbed dose rate at 5㎝ depth in water phantom was determined with measurement error of ±5%. This result was compared to that of the ionization method, indirectly absolute measurement method, of which measurement error of ±2%. The difference between these two results lies within measurement error of LiF : PTFE method. Therefore, the absorbed dose in water obtained by LiF : PTFE is reliable, and this result suggests the base to estimate dose-equivalent for medium X-rays.