7두의 개에서 배설성 요로조영술을 통한 신장 기능 평가

최윤정,이기자,최형준,이용진,박성준,송근호,정성목,최호정,이영원 忠南大學校 獸醫科大學 動物醫科學硏究所 2005 動物醫科學硏究誌 Vol.13 No.-

Excretory urography is a type of contrast study used to verify and localize upper urinary tract disease. It is an inexpensive and easy way to visualize of anatomic and functional status of the kidney and has been used as a primary imaging modality for the evaluation of urinary tract abnormalities. We describe urological signs of 7 dogs who examined with excretory urography and ultrasonography. Six cases were referred to veterinary medical teaching hospital. Chungnam national university (VMTH, CNU) to evaluate renal function after the treatment for renal failure and one case was referred showing hematuria. In case 1, 2 and 4, blood test and urinalysis was normal and the results of excretory urography presented that renal function were normal range. In case 3, the results of urinalysis, ultrasonography, and excretory urography except blood test presented abnormal kidney and hydronephrosis was diagnosed. In case 5 and 6, blood test, urinalysis, ultrasonography and excretory urography indicated renal failure. In case 7, blood test, urinalysis and ultrasonography presented partially abnormal signs, however, the results of excretory urography was normal range.

김치에서 분리한 Lactobacillus sp. JC-7과 Lactobacillus acidophilus 88간의 Electrofusion 최적조건 설정

조영배,최현정,백형석,전홍기 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

김치 발효 숙성기간을 연장하고 신선도를 오랫동안 유지 할 수 있는 김치발효 starter의 개발을 목적으로 최적숙성기에 있는 김치로부터 bacteriocin생성능이 없는 유산균을 분리하여 동정하였으며, bacteriocin생성능이 우수한 L.acidophilus 88을 융합시키기 위해 electrofusion에 대한 최적 조건을 검토하였다. 분리균주는 Lactobacillus속으로 동정되어 Lactobacillus sp. JC-7이라 명명하였다. Electrofusion에 의해 생성된 융합주를 식별하기 위해 streptomycin(2.5㎎/ml)에 내성을 나타내는 Lactobacillus sp. JC-7변이주와 kanamycin(600㎍/ml)에 내성을 나타내는 L.acidophilus 88변이주를 분리하였다. Electrofusion을 100V/㎝, 120msec(72ohms,1670 capacitance) 에서 수행했을 때 융합효율이 가장 양호하였으며 전기장의 세기와 시간이 중가할수록 융합 효율이 현저히 감소하였다. 2가 양이온은 농도가 중가할수록 대체적으로 융합효율을 감소시키는 경향을 나타내었으나 1mM MGCl_2에서는 대조군에 비해 융합효율이 약간 증가하였다. PEG매개에 의한 융합법의 융합효율을 비교한 결과, 융합효율은 chemical fusion<electrofusion<electrofusion+20% PEG순을 나타내었다. Evaluation of Optimum Conditions for the Electrofusion between Lactobacillus sp. JC-7 Isolated from Kimchi and Lactobacillus acidophilus 88. Young-Bae Jo, Hyun-Jung Choi, Hyung-Suk Baik and Hong-Ki Jun*. Department of Microbiology, Pusan National University, Pusan 609-735,Korea-A lactic acid bacterium was isolated from kimchi. The isolated strain was identified as the genus Lactobacillus thrugh its morphological characteristics and named as Lactobacillus sp. JC-7. The optimum conditions for the electrofusion between streptomycin(2.5㎎/ml)resistant mutant of Lactobacillus acidophilus 88 and kanamycin(600㎍/ml) resistant mutant Lactobacillus sp. JC-7 were evaluated. The highest number of fusants were obtained at a capacitance value of 120msec(1670㎌), a field strength of 100V/㎝,and a pulse controller setting of 72Ω. The potimum pH of elecroporation buffer was 7.5 and the concentration of divalent cation was 1mM MG^2+. Electrofusants were efficiently obtained by addition 20% polyethylene glycol to electroporation buffer. The yield of fusion was better than that of using polyethylene glycol mediated chemical induction.

말기신부전 환자의 혈색소 순환 : 투석 방식에 따른 양상 비교 및 관련 인자들에 대한 고찰

최재혁,김준섭,원기범,박준형,탁우택,이정호 동국대학교 의학연구소 2009 東國醫學 Vol.15 No.2

혈색소 순환은 말기신부전 환자에서 인체 재조합 적혈구 조혈 인자를 투여하여 빈혈을 치료하는 동안 빈번히 관찰되며 이는 환자의 입원과 사망률과 관계가 있다고 알려져 있다. 이에 저자는 투석중인 말기 신부전 환자를 대상으로 혈색소 순환 양상과 이와 연관된 인자들을 알아보고자 하였다. 혈색소 순환의 관련 인자들을 알아보기 위하여 투석 치료를 받고 있는 환자 40명 (혈액투석 환자군: 20형, 복막투석 환자군: 20명)을 대상으로 투석 시작부터 1년 동안의 환자의 나이와 성별, 투석시작 1년간의 평균 Hb, 수혈 횟수, 총입원 횟수, 감염으로 인한 입원 횟수, 혈청 ferritin 농도, 혈청 transferrin saturation (TSAT), 철분제제 복용 유무, 일주일 동안 투여된 rHuEPO 양, rHuEPO의 변화량, 알부민, C-reactive protein (CRP) 및 입원 원인 등을 후향적으로 조사하였다. 전체 환자 40명 중 33명 (82.5%)에서 혈색소 순환이 관찰되었다. 혈액투석 환자군에 비해 복막투석 환자군에서 혈색소 순환 첫수가 유의하게 높았다 (p=0.037).혈색소 순환 발생군과 혈색소 순환 미발생군의 관련인자들을 비교하였을 경우 혈색소 순환 발생군에서 총 입원 첫수 (p=0.01), 감염으로 인한 입원 횟수 (p=0.036)가 유의하게 많았으며, 혈중 알부민 수치는 유의하게 낮았다 (p=0.003).그러나 두 군간의 나이, 성별, 수혈 횟수, 혈청 ferritin농도, 혈청 transferrin saturation (TSAT) 및 혈청 철분 농도는 유의한 차이가 없었다. 혈색소 순환의 빈도는 일주일 동안 투여된 r-HuEPO변화량과 양의 상관관계를 보였고 (p=0.003),혈중 알부민 수치와 음의 상관관계를 보였다 (p=0.013). 복막투석 환자군에서 혈액투석 환자군에 비해 혈색소 순환이 유의하게 높게 발생하였다. 일주일 동안 투여된 r-HuEPO 변화량, 입원 및 혈청 알부민 수치는 투석 시작부터 1년 동안의 혈색소 순환과 관련이 있었다. Hemoglobin cycling is frequently observed during treatment of anemia with recombinant human erythropoietin (r-HuEPO) in patients with end stage renal disease (ESRD) it is also reported to be associated with hospitalization and morbidity. We analyzed hemoglobin cycling and potential associated factors in patients on dialysis. Forty new dialysis patients (20 hemodialysis, HD and 20 peritoneal dialysis, PD) were recruited during their first year. Age, gender, mean hemoglobin level, frequency of transfusion, frequency of hospital admission, frequency of admission due to infection, serum ferritin, transferrine saturation, iron levels, rHuEPO dose per week, serum albumin, and c-reactive protein were retrospectively evaluated in order to examine the possible correlations with hemoglobin cycling. Thirty-three patients (82.5%) were identified in the hemoglobin cycling group. The PD group had a higher frequency of hemoglobin cycling than did the HD group (p=0.037). The hemoglobin cycling group showed a significantly higher frequency of hospital admission (P=0.001), admission due to infection (p=0.036) and a lower serum albumin level (p=0.003) than the other group, but there was no significant difference between the groups for age, gender, frequency of transfusion, serum ferritin, transferrine saturation, and iron levels. The frequency of hemoglobin cycling showed a positive correlation with the i-HuEPO dose variation per week (p=0.003) and a negative correlation with serum albumin level (p=0.013). The PD group had a higher frequency of hemoglobin cycling than the HD group, and the change of rHuEPO dose per week, hospitalization and serum albumin were associated with the hemoglobin cycling during the first year of dialysis.

연세대학교 치과병원에 내원한 어린이에서의 영구치 맹출 시기 및 순서

강태성,최병재,권호근,손홍규,최형준 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

치아의 정확한 맹출 시기와 그 순서는 어린이의 발육 성숙도의 지표로서 소아치과 임상 및 예방 교정치료에 있어서 매우 중요하다. 이에 2001~2003년에 연세대학교 치과대학병원 소아치과에 내원한 어린이중 만 5세부터 만 14세까지의 남자 654명, 여자 542명, 총 1,196명의 자료를 수집하여 영구치의 맹출 시기 및 순서에 대한 연구 결과 다음과 같은 결론을 얻었다. 1. 상악 영구치의 맹출 시기는 중절치 남 만6.81세, 여 만6.78세, 측절치 남 만8.30세, 여 만7.98세, 견치 남 만10.28세, 여 만10.04세, 제1소구치 남 만9.74세, 여 만9.90세, 제2소구치 남 만10.87세, 여 만10.41세, 제1대구치 남 만6.25세, 여 만6.54세, 제2대구치 남 만12.21세, 여 만12.03세, 여 만12.03세였다. 2. 하악 영구치의 맹출 시기는 중절치 남 만6.00세, 여 만6.06세, 측절치 남 만6.99세, 여 만6.74세, 견치 남 만9.83세, 여 만9.17세, 제1소구치 남 만9.92세, 여 만9.75세, 제2소구치 남 만10.66세, 여 만10.39세, 제1대구치 남 만5.99세, 여 만5.75세, 제2대구치 남 만11.92세, 여 만12.17세였다. 3. 영구치의 맹출 순서는 상악에서 제1대구치, 중절치, 측절치, 제1소구치, 견치, 제2소구치, 제2대구치의 순이었고, 하악에서 제1대구치, 중절치, 측절치, 견치, 제1소구치, 제2소구치, 제2대구치의 순이었다. Accurate timing and sequence of eruption of permanent teeth are indicies of growth and essential for pediatric dentistry and pediatric clinical orthodontics. From the children brought to the Yonsei Dental Hospital during 2001 to 2003, 654 boys and 542 girls, ranging in age from five to fourteen years, were selected and analysed. The following was concluded. 1. Eruption time of maxillary teeth is 6.81 years in boys, 6.78 years in girls for central incisor, 8.30 years in boys, 7.98 years in girls for lateral incisor, 10.28 years in boys, 10.04years in girls for canine, 9.74 years in boys, 9.90 years in girls for first premolar, 10.87 years in boys, 10.41 years in girls for second premolar, 6.25 years in boys, 6.54 years in girls for first permanent molar, 12.21 years in boys, 12.03 years in girls for second permanent molar. 2. Eruption time of mandibular teeth is 6.00 years in boys, 6.06 years in girls for central incisor, 6.99 years in boys, 6.74 years in girls for lateral incisor, 9.83 years in boys, 9.17 years in girls for canine, 9.92 years in boys, 9.75 years in girls for first premolar, 10.66 years in boys, 10.39 years in girls for second premolar, 5.99 years in boys, 5.75 years in girls for first permanent molar, 11.92 years in boys, 12.17 years in girls for second permanent molar. 3. The following eruption sequence was observed: the first permanent molar erupted first, followed by the central incisor, the lateral incisor, the first premolar, the canine, the second premolar and the second permanent molar in the maxilla. The first permanent molar erupted first, followed by the central incisor, the lateral incisor, the canine, the first premolar, the second premolar and the second permanent molar in the mandible.

Hypophosphatasia 환아의 치료 증례

최병제,최형준,이제호,김기덕,박수정 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.3

1. Hypophosphatasia 는 골조직 및 치아조직의 비정상적인 석회화를 나타내는 대사장애로, 특징적구강내 소견 인 우치의 조기탈락 양상으로 치과에서 조기진단이 가능하다. 2. 본 증례에서 상악궁 확장을 동반한 의치 제작으로 심미적, 기능적으로 양호한 결과를 얻었으며, 영구치열기 까지 장기적 관찰 및 치료가 필요할 것으로 사료된다. hypophosphatasia is a rare metabolic disorder which manifests characteristics such as abnormal mineralization of bone and dental tissues, diminished serum and tissue alkline phosphatase, and increased urinary secretion of PEA. It ingerited as an autosomal recessive or dominant trait and occurs in all races. In general, hypophosphatasia can be classified in 4 subtypes which are the perinatal, infantile, childhood, adult type depending upon the age at presentation and severity. In young children with Hypophosphatasia the long bones show irregular defects, and the skull showes poor calcification. In older children with premature closure of the skull sutures there may ve multiple lucent area called gyral or convolutional markings, described as resimbling beaten copper, presumably resulting from increased intracranial pressure,Examination of the jaws reveals a generalized lucency of the maxilla and mandible, the cortical bone and lamina dura are thin, and the alveolar bone may be deficient. Clinical features of Hypophosphatasia imclude premature loss of deciduous teeth, especially incisors, hypoplasia of aplasia of root cementum, enamel hypoplasia, irregular calcification of dentin, large pulp chamber, and resorption of marginal alveolar bone and roots. Our report involves a patient with a chief complaint of early loss of both Mx. and Mn. deciduous ncisors. after conducting a through clinical and radiographic examination this patient was referred to pediatrics under the suspicion of hypophosphatasia, the diagnosis proved to be correct and successful results were accomplished through a denture made to improve esthetics and function.

계열화 및 전공코스제 운영방안

최병태,이형민,홍성준,정두진,김대곤 대구산업정보대학 2000 논문집 Vol.14 No.2

This paper is an attempt to propose our study that draw up a plan about faculty and major course to the Daegu Polytechnic College authorities. Our approach is a mixture of methods. It is systematic, in that it attempts to treat a college as a system. Through the second chapter, we examine the periodic, social, environmental, governmental, and economic context within which the College's developing effort must progress. Chapter three examines how the college systems actually design about faculty and major course. Thus, chapter four discusses how new faculty and major course participants attempt to compose a curriculum; chapter five accesses the institutions available in the College to distribute these designs. In conclusion, this paper presents that the College system would be better nine faculty; education and nurse·health field only be in administration unit, an information field be better divided into two parts: internet computer and information communication, and business and computer design faculty is established as intimate information. After all, the system will be characteristic in its information traits.

혼합치열기 반대교합자에서 상악골 전방견인장치를 이용한 치료증례

최형준,이제호,최병재,김은영 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.3

The prevalence of class Ⅲ malocclusion is approximately 5∼9%, and about one fourth of this malocclusion is due to underdeveloped maxilla. Maxillary protraction appliance is an orthopedic device which promote the growth of a deficient maxilla by applying extraoral force to actively growing patients. The object of using maxillary protraction appliance is to guide a normal growth of maxilla and mandible and improve the occlusal relationship and also improve the facial profile. The author treated three patients whom were diagnosed as a class Ⅲ malocclusion due to deficient maxilla using maxillary protraction appliance and the followings are the conclusions : 1. In these cases, anterior crossbite was corrected by anterior movement of maxilla and downward backward rotation of mandible and simultaneously, anterior facial height was increased. 2. The amount of dental change compare to skeletal change was greater as the patients got older. 3. When 500gm of force to each side was applied, the treatment period has been decreased. 4. As a result of applying the force between maxillary first primary molar and canine, there was a small degree of changes in palatal plane. So, it can be concluded that the maxillary protraction appliance is effective in treating growing patients with a deficient maxilla.

Open-face Stainless Steel Crown을 이용한 유전치의 치료에 대한 증례보고

최형준,이제호,최병재,김종민 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.4

In spite of the improvements of the techniques in the field of preventive dentistry, many children still present with extensive destruction of primary anterior teeth. Not only the practioner must consider the pulp state of the primary incisor, but also restore the form, function and esthetics of the tooth. Restorative treatment of primary incisor tooth requires durability, retention and esthetics. Stainless steel crowns used in restoring primary anterior teeth is retentive and durable in comparison with the composite resin, celluloid crown. But they are not esthetic. To enhance the esthetics of the anterior stainless steel crown without reducing its superior retention, an open-face stainless steel crown has been suggested. Several authors have suggested cutting away the labial portion of the stainless steel crown and placing the composite resin in that area. By following this technique, the practioner can prepare a retentive, durable, and esthetic restoration for primary teeth which have suffered from extensive loss of teeth structure. In addition, the single missing primary anterior teeth can be successfully restored by soldering the stainless steel crown together. Open-face stainless steel crown is indicated in the areas of large interproximal lesions involving incisal edge, crown fracture with pulp exposure and congenital malformation of the teeth. By this technique, the practioner can restore primary anterior teeth successfully regardless of the amount of remaining tooth structure, bruxism habit and presence of attrition. In this case, rampant caries with extensive loss of tooth structure and single missing of primary anterior tooth hart been successfully treated with open-face stainless steel crown.

건축물의 노후도 평가 방안에 관한 연구

최준영,고은형 啓明專門大學 産業開發硏究所 1999 啓明硏究論叢 Vol.17 No.2

건물이 고령화됨에 따라 건물이 갖는 내구성, 안전성, 기능성 등 기본성능의 저하와 건물을 구성하는 각 구성부위의 결함상태에 의해 건물전체가 기대하는 성능을 발휘하지 못하게 된다. 따라서 시간의 경과에 따라 발생하는 마모나 기능저하 등의 상태를 수시로 체크할 수 있는 일정한 형식을 지닌 체크리스트의 확립이 필요하다. 이에 본 연구에서는 관리대상시설 전반의 신속한 노후도 상황파악을 위해 시설관리대장 및 보수공사 이력표, 관리자 및 전문가에 의 한 체크리스트(시설점검카드) 작성방안을 제시하고 있다. As time goes on, the total performance of buildings is on the decrease in the point of durability, safety and function. Therefore, it is needed to establish the official building condition checklist to prevent the building from its superannuation and disorder. Thus the study aims to provide the evaluation method based on building maintenance reports and opinions of professionals to check rapidly the degree of superannuation of facilities.

아르곤 레이저를 이용한 광중합 수복재의 물리적 성질에 관한 연구

최형준,주상호,김성오,이종갑 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.2

The purpose of this study is to evaluate and compare the results of argon laser for 5 seconds, argon laser for 10 seconds, and visible light for 40 seconds photo-polyerization in compressive strength, microhardness, curing depth, temperature rising during polymerization, and polymerization shrinkage. Hybrid type composite resin(Z-100) and compomer (Dyract) were used to be compared. The compressive strength was measured by an Instron (1mm/min cross head speed) in 60 specimens and the microhardness of the surface was expressed by Vickers Hardness Number (VHN) in 30 specimens. The curing depth was evaluated comparing the different values of upeer and lower VHN according to irradiation time and thickness for the light sourece polymeriaztion in 60 specimens. the temperature rising during photopolymerization was observed by the temperature change with thermocouple sensitizer beneath 40 specimens at th argon laser for 10 seconds and visible light 40 seconds irradiation. the polymerization shinkage was evaluated by calculating the decrease of % volume by using a dilatometer in 30 specimens. The results were as follows : 1. In the case of compressive strength, the argon laser polymerization groups were higher than visible light group in Z-100 (p<0.05). In Dyract, the argon laser 5 seconds group did not show a significant difference with the visible light 40 seconds group. The argon laser 10 seconds group showed the markedly low value when compared with other g개ups (p<0.05) 2. In micriohardness, Z-100 was better than Dyract when comparing by VHNs(p<0.05) ; however, there was not a significant difference between two materials in the visible light 40 seconds group and the argon laser 10 seconds groups. 3. In the study of curing depth, Z-100 showed the consistent polymerization in argon laser irradiation because there was no difference in the VHN decrease according to the thickness change. Over the thickness control, the results did not show a significant difference between visible light and argon laser group in Z-100 ; however, in the case of Dyrct, the visible light 40 seconds group was better than the argon laser groups(p<0.05). 4. There was a significant difference between the two materials in temperature rising during polymerization (p<0.05), but not a significant difference between irradiation times. 5. There was not a significant difference between the two materials in polymerization shrink-age. The argon laser 5 seconds group was smaller than the other groups (p<0.05). It could be concluded that z-100 polymerization was recommended to use the argon laser for reduction of the irradiation time while Dyract was recommended to use the visible light polymerization.