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철 산화균(Thiobacillus ferrooxidans)을 이용한 황화수소 제거-온도변화에 따른 황화수소 제거효율변화
박양호,손효진,김려화,권규혁,이중헌 한국공업화학회 2002 응용화학 Vol.6 No.2
Effects of temperature on hydrogen sulfide removal efficiency has been studied in this research. Two reactors which combined iron oxidization reactor and reduction reactor were manufactured. Iron oxidation reactor was used to oxidize Fe(II) to Fe(III) with Thiobacillus ferrooxidans and the hydrogen sulfide was oxidized to make element sulfur with the reduction of iron. The optimal temperature for the iron oxidation was 30℃ however that of iron reduction was 40℃. From this result, the optimal continuous operation conditions has been determined.
박양호,손효진,김경주,권규혁,이중헌 한국공업화학회 2003 응용화학 Vol.7 No.1
In this study, the hybitd reactor has used to remove H_2S from the toxic gas. Since the oxidation and reduction reactors were combined, theri sizes were important to stabilize developed process. The optimal sizes of oxidation and reduction reactors were determined considering iron oxidation rate and H_2S removal rate. The optimal ratio of reactor size was 4 L for oxidation reactor to 1 L for reduction reactor.Immobilized Thiobacillus ferrooxidans has been developed to minimize the size of oxidation reactor. Since the immobilized cell enhanced the oxidation rate, it was possible to incrase H_2S removal efficiency. It was possible to incerase operation time because immobilized cell can survie lger than free cell.
Progress and plans for the observational data assimilation module development at KIAPS
Hyo-Jong Song,Hyoung-Wook Chun,Su Jin Ha,Youngsoon Jo,Byoung-Joo Jung,Jeon-Ho Kang,Ji-Sun Kang,Hataek Kwon,Jihye Kwun,Sangil Kim,Ju-Hye Kim,Sihye Lee,Jooyeon Lim,Jong-Im Park,Young-Joon Kim 한국기상학회 2013 한국기상학회 학술대회 논문집 Vol.2013 No.4
림프절 전이가 발견되지 않은(cN0) 유두상 갑상선 암의 중앙 경부 림프절 분석
김윤정(Yun Jung Kim),하태권(Tae Kwun Ha),유성목(Sung Mock Ryu),김상효(Sang Hyo Kim) 대한두경부종양학회 2010 대한두경부 종양학회지 Vol.26 No.2
Purpose :Papillary thyroid carcinoma (PTC) is known for malignant tumor which has a favorable prognosis and long-term survival. Although the prognosis for patients with PTC is generally good, PTC tends to have highly metastatic property. The purpose of this study was to analyze the central compartment lymph node in papillary thyroid cancer with no lymph node metastasis clinically and to assess the significance of prophylactic node dissection. Methods :A retrospective review was carried out in 394 patients with PTC who underwent sur-gery for the period from January 2004 to December 2006. The positive rate of the lymph node metastasis was analyzed. The relations between the central compartment lymph nodes and the patients’ age, gender, tumor size, exrathyroidal extension(ETE), multifocality, and bilaterality were comparatively analyzed in PTC patients with preoperative no lymph node metastasis. Results :The enrolled patients were 40 male and 354 female cases. The 118 cases of them were found to have cervical lymph node metastasis. The mean age was 46 years(range, 15-77years). Tumor size(p=0.000), ETE(p=0.001), multifocality(p=0.014), and bilaterality(p=0.001) were significantly related factors for cervical lymph node metastasis clinically in papillary thyroid cancer. However, age and gender were not significantly related with lymph node metastasis. Conclusion :Although no lymph node metastasis clinically, prophylactic neck node dissection can be performed to avoid risks of local recurrence and reoperation in the light of PTC nature. The pathological status and high positive rate of central compartment lymph node relate to tumor size and extrathyroidal extension. Close surveillance for nodal status is required in follow-up.
Choi, Jun-Young,Kwun, Min Jung,Kim, Kyun Ha,Lyu, Ji Hyo,Han, Chang Woo,Jeong, Han-Sol,Ha, Ki-Tae,Jung, Hee-Jae,Lee, Beom-Joon,Sadikot, Ruxana T.,Christman, John W.,Jung, Sung-Ki,Joo, Myungsoo Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-
<P>The fruit hull of <I>Gleditsia sinensis</I> (FGS) has been prescribed as a traditional eastern Asian medicinal remedy for the treatment of various respiratory diseases, but the efficacy and underlying mechanisms remain poorly characterized. Here, we explored a potential usage of FGS for the treatment of acute lung injury (ALI), a highly fatal inflammatory lung disease that urgently needs effective therapeutics, and investigated a mechanism for the anti-inflammatory activity of FGS. Pretreatment of C57BL/6 mice with FGS significantly attenuated LPS-induced neutrophilic lung inflammation compared to sham-treated, inflamed mice. Reporter assays, semiquantitative RT-PCR, and Western blot analyses show that while not affecting NF-<I>κ</I>B, FGS activated Nrf2 and expressed Nrf2-regulated genes including GCLC, NQO-1, and HO-1 in RAW 264.7 cells. Furthermore, pretreatment of mice with FGS enhanced the expression of GCLC and HO-1 but suppressed that of proinflammatory cytokines in including TNF-<I>α</I> and IL-1<I>β</I> in the inflamed lungs. These results suggest that FGS effectively suppresses neutrophilic lung inflammation, which can be associated with, at least in part, FGS-activating anti-inflammatory factor Nrf2. Our results suggest that FGS can be developed as a therapeutic option for the treatment of ALI.</P>
Kyung Min Kim,Hyo Sup Kim,Ji Hong Yoon,Eun-Jung Lee,Sook Kyung Yum,Cheong Jun Moon,윤영아,Yoo Jin Kwun,이재영,성인경 대한신생아학회 2018 Neonatal medicine Vol.25 No.2
Purpose: To investigate the hemodynamic risk factors for necrotizing enterocolitis (NEC), we analyzed the characteristics of descending aorta (DA) blood flow in preterm neonates, who later developed NEC. Methods: This was an observational case-control study on 53 preterm neonates at a tertiary referral center. Clinical and echocardiographic data were collected from 23 preterm neonates with NEC (NEC group), and compared with those of 30 preterm neonates without NEC (control group). Echocardiography was done at a median (interquartile range) of 5 (3-9) days after birth and 2 (1-2.5) days before the diagnosis of NEC. Results: Basic clinical characteristics including gestational age, birth weight, Apgar score, breast feeding status, use of umbilical catheters, and mode of invasive ventilator care were similar between the groups. Compared with the control group, the lowest diastolic velocity of DA was significantly decreased, whereas the diastolic reverse flow and the ratio of diastolic reverse to systolic forward flows were significantly increased in the NEC group. In addition, the resistive index (RI) of DA was significantly increased in the NEC group and showed a positive association with the development of NEC. Multivariate logistic regression analysis showed that increasing RI of DA was an independent risk factor for the development of NEC (P=0.008). Conclusion: Significant changes in DA flow characteristics including decreased diastolic velocity and increased diastolic reverse flow along with increased peripheral vascular resistance were observed before the development of NEC in preterm neonates. These findings may help clinicians stratify in advance neonates at a risk of developing NEC and may help improve outcomes in these neonates.
임효주,안재성,권양,이정교,권병덕,Lim, Hyo Joo,Ahn, Jae Sung,Kwon, Yang,Lee, Jung Kyo,Kwun, Byung Duk 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.6
Objectives : The purpose of this study was to evaluate the clinical features of the epidermoid tumor of posterior fossa and to assess the surgical outcome. Methods : We reviewed the clinicoradiological records of 10 epidermoid tumor of posterior fossa, treated surgically at our hospital between 1991 and 1996. Results : The mean age of onset was 36 years old and mean duration of symptom was 5.2 years. Six were men and four were women. The location of tumors were cerebellopontine angle(CPA) 5 cases, cerebellum(Cbll)& 4th ventricle 3 cases, foramen magnum 1 case, and pineal region extended to Cbll and 4th ventricle 1 case. Common clinical features were trigeminal neuralgia in 3 cases, cerebellar signs 2 case, headache 2 cases, hemifacial spasm with deafness 1 case, cbll signs and multiple cranial nerve dysfunctions 1 case. One CPA epidermoid had no clinical symptom and sign associated with the tumor. The surgical approaches were suboccipital approach in 9 cases and one transcallosal approach to the tumor of pineal region. The extent of surgical removal was gross total resection in 5 cases and near total or subtotal resection in 5. Two patients with CPA tumor were complicated with facial paresis. One patient with tumor located in cerebellum extended into cisterna magna had postoperative vocal cord paresis. All complicated cases had severe adhesion of tumor capsule with brainstem or cranial nerve. The mean duration of follow up was 26 months. The overall outcome was improvement of symptoms and signs in 6 cases and stationary 4 cases. During follow up, imaging study was done in 7 patients and none of them had finding of tumor recurrence. Conclusion : We conclude that recurrence of tumor is rare in both total and subtotal resected cases, but long-term follow-up is required. Aggressive removal of tumor capsule that adhesed to brianstem or cranial nerve is avoided for preventing severe postoperative complication.
임효주,권양,안재성,김정훈,김창진,이정교,권병덕,Lim, Hyo Joo,Kwon, Yang,Ahn, Jae Sung,Kim, Jeong Hoon,Kim, Chang Jin,Lee, Jung Kyo,Kwun, Byung Duk 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.8
Objective : We analysed diverse clinical features of the cavernous angioma. Also, we report the experience in differ-ent methods of the management and their results. Method : Data from 80 patients who were confirmed pathologically or diagnosed radiologically between Jan. 1990 and Sept. 1998 at our hospital were analysed. Variable factors that were examined were : clinical features, effects of treatment, and complications. Results : There were 47 male and 33 female patients. The age at the first presentation was from 3 to 57(mean 34.1) years old. Clinical features were seizure in 28 cases(38%), bleeding in 24 cases(32%), neurologic deficits in 12 cases(16%), headache in 10 cases(14%), and six incidental cases. The locations of lesion were cerebral and cerebellar hemisphere in 45 cases(56.2%), brainstem, basal ganglia, and thalamus in 32 cases(40%), multiple in 3 cases (3.8%). Seizure was common at the third decade and occurred frequently with the cavernous angioma in temporal (43%) or frontal lobe(39%). Bleeding was frequent after the third decade with peak at the fourth decade and had high incidence in brainstem or thalamus. The gamma-knife radiosurgery was done in 47 cases. Rebleeding occurred in 3 cases, but it was within postradiosurgery 1 year. Symptomatic radiation change occurred in 2 cases of 8 radiation change on MRI. On follow-up MRI, no evidence of rebleeding was found in 30 cases. Also, The lesion size was decreased in 3 cases. Resection was performed in 23 cases ; total 20, subtotal 2, partial 1. Postoperative complication occurred in 6 cases(26.1%). After surgery, 7(63.6%) of 11 seizure patients had outcome of seizure-free. Subclinical rebleeding occurred in one of two subtotal resected cases. In 11 patients, conservative management was done. There was neither rebleeding nor symptom aggravation during follow-up period of mean 17.2 months. Conclusion : The solution for prevention of rebleeding is complete removal of the lesion located at noneloquent area or accessible region, especially for the patients who presented symptoms or intractable seizure. However, the Gamma knife radiosurgery is considered when the lesions are located at eloquent area or when severe postoperative morbidity is expected.