BaFBr:Eu²+,Na+ 영상판 제작과 특성

김찬중,김성환,이병화,김완,강희동,김도성,서효진,도시홍 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1

흰쥐의 방사선 피폭후 생물학적 지표로서의 혈액효소

김진규,김상복,김국찬,천기정,김인규,박효국,이강석 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.2

생물학적 선량평가를 위한 생화학적 지표 연구로서 흰쥐 혈액내 효소활성도의 변화를 조사한 결과는 다음과 같다. 1) Alkaline phosphatase 활성도는 0.1, 0.25, 0.5, 2, 4 Gy의 방사선 조사후 24시간까지 혈액내 활성도가 증가하였고 72시간 경과시에는 대조군과 비슷한 활성도를 보였다. Creatine kinase는 2, 4 Gy 방사선 조사후 혈액내에서 활성도에서 활성도가 72시간까지 증가하였으나 0.1, 0.25Gy, 0.5 Gy 방사선 조사시에는 커다란 변화를 보이지 않았다. 2) Malate dehydrogenase 활성도는 0.1, 0.25, 0.5 Gy 방사선 조사시에는 커다란 변화가 없었으며 lactate dehydrogenase는 방사선 조사후 활성도가 감소하였다. 3) GOT의 활성도는 선량률 0.1Gy/min.로 0.1, 0.25, 0.5, 2, 4 Gy 조사후에는 어떠한 변화도 없었으며 선량률 0.5 Gy/sec.로 0.5, 1, 1.5, 2, 3, 5, 7 Gy로 조사후에는 증가현상을 보이고 있다. Acid phosphatase 활성도는 상기의 어떠한 선량에서도 나타나지 않고 있다. 잠재적으로 이러한 효소들은 방사선 피폭의 지표물질로 사용될 수 있으며 생화학적 지식과 기술을 이용한 좀더 나은 지표물질을 찾기 위하여 계속적인 조사가 필요하다. Enzyme activity changes in rat blood as biochemical indicator useful for evaluating exposure dose were experimentally studied. The experimental results obtained are as follows: 1) Alkaline phosphatase activities increased in the blood serum until 24 hours after 0.1, 0.25, 0.5, 2 and 4 Gy irradiation and its activities returned mormal condition after 72 hours of post-irradiation. Creatine kinase activities increased in the blood serum until 72 hours after 2 and 4 Gy irradiation but any significant activity changes were not detected after 0.1, 0.25 Gy irradiation. 2) Malate dehydrogenase activities did not reveal available changes changes after 0.1, 0.25, 0.5 Gy irradiation and lactate dehydrogenase activities decreased in the blood serum after 0.1, 0.25, 0.5 Gy irradiation. 3) Glutamate oxaloacetate transaminase activity changes were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4 Gy(0.1 Gy/min.) and GOT activities increased after 0.5, 1, 1.5, 2, 3, 5, 7 Gy(0.5 Gy/sec.). Any acid phosphatase activities were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4 Gy(0.1 Gy/min.) and 0.5, 1, 1.5, 2, 3, 5, 7 Gy(0.5 Gy/sec.) irradiation. Potentially some of these enzymes can be used as indicator protein for radiation injury. Futher investigation is needed to find better biochemical indicatiors utilizing recent knowledge and techniques of biochemistry.

SrCI_2:Eu^2+ 형광체의 광발광 및 광자극발광 특성

도시홍,서효진,김영국,김도성,김성환,김찬중,이병화,김완,강희동 한국센서학회 2002 센서학회지 Vol.11 No.6

고상반응법으로 SrCl_2:Eu^2+ 형광체를 제작하고, 제작한 형광체의 광자극발광과 광발광 특성을 조사하였다. SrCl_2:Eu^2+ 형광체와 광발광 및 광자극발광은 Eu^2+ 의 5d->4f 천이에 기인되었으며, 355 nm의 광으로 여기시켰을 때 광자극발광과 광발광 스펙트럼의 파장범위는 모두 380~440nm이었고, 피이크 파장은 407nm이었다. SrCl_2:Eu^2+형광체의 선량의존성은 2.5 mGy~200mGy영역에서 우수한 선형성을 나타내었으며, 상온에서 광자극발광의 fading은 20분에 60%이었다. SrCl_2:Eu^2+ phosphors were prepared by the solid phase reaction method, and their photostimulated luminescence(PSL) and photoluminescence(PL) characteristics were investigated. The PSL and PL peak of the SrCl_2:Eu^2+ phosphors are due to the 5d->4f transition of Eu^2+ ions in phosphors. The PSL and PL spectrum obtained by the 355 nm exitation was observed in 380~440 nm region with the peak at 407 nm. The dose response of the PSL phosphors were linear within 2.5 mGy ~ 200 mGy of 100kV X-ray. The fading of the phosphors at room temperature was approximately 60% after 20 min.

BaFBr:Eu^2+ 형광체의 열발광 및 광자극발광 특성

도시홍,서효진,강갑중,김영국,김도성,김성환,김찬중,이병화,김완,강희동 한국센서학회 2002 센서학회지 Vol.11 No.5

BaFBr:Eu^2+ 형광체를 제조하고, 이 형광체의 열발광 특성과 광자극발광 특성을 조사하였다. 이 형광체의 열발광 g1ow 피이크 온도는 352K와 448K였으며, 주 피이크(352K)에 관여하는 트랩의 활성화에너지는 약 0.96eV이었다. 또한 이 형광체의 광자극발광 스펙트럼의 파장범위는 350~450nm 사이였으며, 광자극발광에 기여하는 트랩의 활성화에너지는 약 0.98eV이었다. 열발광트랩과 광자극발광 트랩의 활성화에너지는 실험오차 내에서 일치하였다. BaFBr:Eu^2+ phosphors were prepared, and the thermoluminescence(TL) and photostimulatedluminescence(PSL) of the prepared phosphors were measured. Two glow peaks around 352 and 448 K are observed for x-ray irradiated BaFBr:Eu^2+ phosphors, and the activation energy of the main glow peak(352 K) was about 0.96 eV. The spectral range of the PSL was 350 ~450 nm, and the activation energy of the trap giving rise to PSL was about 0.98 eV. The activation energy of the traps giving rise to TL is agreed to those giving rise to PSL within experimental error.

제 3형 Gaucher세병으로 인한 진행성 근간대성 간질 2예

허경,예종수,김상진,김성은,김응규,조효근,김찬환,김현주 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

ISC3모델을 이용한 버스터미널 주변의 질소산화물 농도 예측

김문찬,류효상 청주대학교 산업과학연구소 2008 産業科學硏究 Vol.26 No.1

In this study, NOx concentration was investigated around the local/highway bus terminal area by using ISC3 model. NOx concentrations were simulated by the yearly mean values which were in the morning, in the afternoon and at night. As the result of the verification and the calibration for the model accuracy, the correlation coefficients was 0.94. Therefore, ISC3 model was suitable for this area. In the result of NOx concentration using ISCLT3, the average concentration of NO2 was 13.05 ppb. The range of influence that engine emissions affected terminal area, was larger in the morning than in the afternoon. Because mixing height was higher in the afternoon than that in the morning, so emissions were diffused toward upper ambient air that range of engine emission influence was narrow. At night, the range of engine emission influence was the largest in a day. Because mixing height was the lowest at night. So horizontal diffusion was dominated than vertical one.

발달장애유아의 언어행동발달 연구

김춘희,변찬석,서경희,유은정,이효신,전헌선,최성규 大邱大學校 特殊敎育·再活科學硏究所 2000 特殊敎育硏究 Vol.23 No.1

본 논문은 발달장애유아 언어행동발달 컨텐츠 개발에 요구되는 기초연구로써 연구의 이론적 바탕을 확립하고자 하였다. 연구에 사용된 방법은 문헌조사 방법 및 현장 인터뷰기법을 병행하였다. 본 연구의 주된 목적은 크게 3가지로 구분된다. 첫째, 발달장애유아의 가정 내 교육 욕구를 분석하고자 하였다. 둘째, 발달장애유아의 언어발달 양상을 검토하고자 하였다. 세 번째 목적은 유아의 언어행동발달 컨텐츠 구성의 주요 지침을 설정하고자 하였다. 이상의 연구목적에 따른 연구결과를 요약하면 다음 몇 가지로 제시된다. 1.가정 내 부모-유아간 관계형성이 우선 고려 되어야하고, 이에 따른 상호작용은 발달적 애착형성이 가능한 방향으로 정립되어야한다. 2.발달장애유아의 언어행동발달양상을 검토한 결과에 따르면, Piaget는 언어행동발달에 있어 감각운동기적 환경탐색 기능을 강조하고 있고, 이는 현재까지 중요한 유아 발달의 기저로 정착되었다. 따라서, 발달장애유아의 언어행동발달을 위한 컨텐츠 개발 내용에 있어서도 이러한 기저에 충실함이 합리적이다. 3.발달장애유아들에게는 언어행동 양상의 갈래가 크게 운동장애 및 감각결함으로 나누어질 수 있으므로, 이 두 가지 갈래의 각기 다른 특성이 컨텐츠 구성에서 충분히 고려되어야한다. 4.자폐성과 같은 중증 전반적 발달장애 유아를 위한 언어행동발달 컨텐츠 구성에서 특히 고려해야 할 두 가지 요소는 모방행동기능과 반복단순훈련기능 향상으로 결론지을 수 있다. This article planed to establish the theoretical foundations of the research as a basic study needed for developing the contents of verbal(language) behavior development for the infants with developmental disabilities. The methods used in the study was previous literature researches and interviews with subjects. The purposes of the study were divided into three parts. First, it was to analyze the educational needs of the infants with developmental disabilities in home settings. Second, it was to review and discover the language patterns of the infants with developmental disabilities. The third purpose was to devise the major guidelines of their language development's contents. The results of the study were described as the followings. 1.The relationships between the infants with developmental disabilities and their parents and their interactions should move to build the developmental attachments between them. 2.According to the literature findings of their language development patterns, Piaget concentrated on the functions of sensory motor environmental exploring in the language behavior development. The functions have been settled down into the important foundation for the infants' development. Thus, it was resonable that the content's development of the language behaviors for the infants with developmental disabilities should based on the function addressed by Piaget. 3.The language behaviors' patterns of the infants with developmental disabilities generally were classified into motor disabilities and sensory defect(deficiency). Therefore, the two factors should be considered for the constructions of the contents. 4.Constructing the contents of the language behavior developments for the infants with severely pervasive developmental disabilities such as autism, the improvements of two functions, imitative behavior and repetitive simple training should be considered.

하지 중량부하 걷기 운동이 비만 청소년의 신체조성에 미치는 영향

김효찬 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

The purpose of this study is to know about the influence of the lower limbs-weight walking exercise on body composition in obese youth For this study, 35 obese students were selected who volunteered in an attempt this case study from D high school in Incheon city and they are all have more than 25% of BMI(㎏/㎡). These students are randomly classified to 3 groups as like; 1) Group with 12 members who they dont exercise at all, 2) Group with 11 members who they do walking exercise, 3) Group with 12 members who they do lower limbs-weight walking exercise. For examine closely into the lower limbs-weight walking exercise, took an accurate measurement of body composition after taking 12 weeks treadmill exercise. To verify of the average values difference before and after walking exercise, I did Paired t-test. And, used One-way ANOVA for whether or not these 3 groups difference. Here are the results from this case study. (1) There is a difference between all groups with the weight from 12 weeks exercise, but no difference with the weight of 2 walking exercise groups. (2) There is no difference after 12 weeks exercise with the body at between the groups, there is more decline of the lower limbs-weight walking exercise group than others. (3) There is no difference between 3 groups with the body at before exercising, however, slight difference can be shown after 12 weeks exercise. Arid, there is more decline founded of the lower limbs-weight walking exercise group than other groups. (4) There is no difference between 3 groups with the breast at before exercise, but after 12 weeks exercise, slight difference can be founded. And, there is more decline founded of the lower limbs-weight walking exercise group than others. (5) There is no difference between groups with the abdomen at before exercising, however, there is a slight difference after 12 weeks exercise. There is more decline founded of the lower limbs-weight walking exercise group. (6) There is a difference between all groups with the thigh fat. However, it can be more declined of the lower limbs-weight walking exercise group than other groups.

Fasciola의 간농양에서 Praziquantel 7일 요법의 임상

김정룡,이효석,채종일,김선미,김찬규 대한감염학회 1997 감염 Vol.29 No.5

목 적 : Fasciola hepatica에 의한 간농양으로 진단 받은 환자에게 장기간 praziquantel을 투여하여, fasciola에 의한 간농양에 대한 장기간의 Praziquantel두여 효과를 알아보고자 하였다. 방 법 : F. hepatica에 의한 간농양으로 진단 받은 3명의 환자를 대상으로 하였다. F. hepatica에 의한 간농양으로 진단한 기준은 1) micro-ELISA에 의한 기생충에 대한 항체검사에서 fasciola 항원에 대한 반응이 양성이고 2) 말초 혈액 검사상 호산구증다증 을 보이며 3) 복부초음파 또는 복부컴퓨터단층촬영상 간질에 의한 간농양의특징적 소견을 보이며 4) 간내점 유병소에 대한 조직검사상 호산구성 농양을 보이는 경우로 하였다. Praziquantel의 투여는 하루 70-84mg/kg으로 7일간 투여 하였다. Praziquantel 투여 후 치료 효과 유무의 판정은 3개월 내에 말초혈액 호산구수의 500/㎣ 이하로의 감소 및 1년 이내에 간농양 의 소멸 여부로 결정하였다. 결 과 : 호산구다증은 2-3개월 내에 정상화 되었고, 간농양은 1예에서 치료 5개월 후에 병변의 크기가 90%이하로 감소하였고 나머지 2예에서 1년 이내에 소실되었다. Praziquantel의 투여를 중단할만한 심각한 부작용은 없었다. 결 론 : 7일간의 praziquantel 투여는 간질증에 의한 간농양에 대해 효과가 있으리라 생각되며 안전하다. Background : Fascioliasis is a zoonotic helminthiasis by fasciola species and is occasionally complicated by liver abscess, and the treatment of choice is oral bithionol, which is not available in Korea. Most clinical reports showed that praziquantel given at usual dosage(75mg/kg for 1day) failed to cure Fasciola fepatica infections, however, it has not been investigated whether long term praziquantel(70mg/kg/d for 7 days) would be effective. We evaluated the effectiveness of long term praziquantel therapy in patients with Fasiola liver abscess. Method : There patients were included in the current study who were diagnosed as liver abscess by F. hepatica. The diagnostic criteria for inclusion were 1) hypereosinophilia, 2) positive serologic test for F. hepatica antigen, 3) characteristic findings on CT scan and 4) demonstration of aggregates of eosinophils on ultrasonography-guided aspirates of the abscess. Praziquantel was given orally to patients at the daily does of 70-84mg/kg for 7 days. the effectiveness was assessed by the normalization of count at the end of 3 months and the disappearance of abscess cavity on ultrasonography or CT scam one year after treatment. Results : Blood eosinophil count decreased to less than 500/mm³ in all patient within 2 to 3 months. The liver abscesses reduced in size by 90% in 5 months in one patient and disappeared within a year in two patients. No major adverse effects were observed. Conclusion : We conclude that 7-day praziquantel therapy may be effective and safe in the treatment of liver abscess caused by F. hepatica.

프랑스어 및 한국어 구강모음의 비교연구 : 컴퓨터 단층 촬영 및 디지틀 음향분광기를 사용하여 by means of Computed Tomography and High-speech Analysis System

김찬양,신효근,홍기환,김연희,김현기 全北大學校 語學硏究所 1994 어학 Vol.21 No.-

The methods of the Computed Tomograph and the High-speed Speech analysis system were used for the comparative study of French and Korean oral vowels. Three male native speackers of French and three Korean speakers were selected for these articulatory and acoustic characteristics. The speech materials were the simple French oral vowels / i, e, ε, a, u, o, ??, a / and the Korean oral vovels / i, e, ε, a, w, u, o /, respectively. The results of these studies are as follows : (1) In the case of articulation, the aperture of Korean closed front unrounded vowels is larger than that of French vowels and the Korean back closed vowel /u/ and the half-closed vowel /o/ did not show significant differences with the corresponding French high vowel /i/. But the aperture of the Korean half-open vowel /??/ is smaller than that of French vowel and in this case, the place of articulation for Korean vowel /??/ is more advanced than that of French vowel /??/ (2) By means of spectrographic analysis of the French and Korean vowels, the first formant of the Korean high vowel /i/ is higher than that of French high vowel /i/. This means that the aperture of the Korean high vowel is larger than that of French high vowel. The second formant of French back vowels are lower than those of Korean back vowels. This result shows that the projection of French back vowels is greater than that of Korean back vowels.