봄철 익산지역 환경대기 중 수용성 이온성분의 일별 침적량

김남송,강공언,김정숙,김현아,신지혜,김병수,최석진 원광대학교 대학원 2008 論文集 Vol.40 No.-

Deposition samples were collected in wet gauge and dry gauge containers at downtown of Iksan city, located southwest of the Korean peninsula, from April 20 to May 1, 2004. The volume of 30-50㎖ deionized water was added for wet gauge before sampling, but dry gauge was installed in the dry state with no deionized water adding. These samples were collected twice a day during daytime and nighttime and were analyzed for anions(Cl^(-), NO^(3-), SO₄^(2-)) and cations (NH₄^(+), Na^(+), K^(+), Mg^(2+), Ca^(2+)) using ion chromatography. Data quality was checked by the data obtained from re-injection of standard solution, Dionex cross check standard solutions, and random several deposition samples, and measured data was estimated to be reliable. Considering the deposition sample volume, the sampling time, the surface area of sampling container, and the ion concentration measured, the deposition amounts were calculated in mg/㎡/day. The sum of ion dry deposition amounts for dry gauge and wet gauge was 9.1±6.7 mg/㎡/day and 26.5±9.1 mg/㎡/day, respectively. A significant increase in deposition amount during rainfall days and Asian yellow dust period was observed for both wet gauge and dry gauge, especially during rainfall days having no difference of deposition amount between in wet gauge and in dry gauge. The mean deposition of all ions measured in this study were higher in wet gauge than in dry gauge because of the surface difference of the sampling container. The mean deposition amount of NH₄^(+), SO₄^(2-), and NO^(3-) in wet gauge were found to be about 27.6 times, 5.5 times, and 3.4 times higher. than that in dry gauge, while the rest of the chemical species were equal or a little higher in wet gauge than in dry gauge. Dominant species in dry gauge were SO₄^(2-) and Ca^(2+), accounting for 14.7% and 47.3% of the total ion dry deposition, whereas those in wet gauge were SO₄^(2-) and NH₄^(+), accounting for 27.7% and 27.1% of the total ion dry deposition, respectively.

체계적인 액션러닝을 활용한 대학원 신입생 학교생활 지원 콘텐츠 개발 및 적용방안 탐색

김혜진,김혜나,김종민,강신범,남기곤,박수홍,강문숙 부산대학교 교육연구소 2012 교육혁신연구 Vol.22 No.3

발신번호 확인 서비스 개발

윤혜숙(Yoon Hye_Suk),황우근(Hwang Woo_Geun),김진수(Kim Jin_Soo),이상일(Lee Sang_Il) 대한전자공학회 1992 대한전자공학회 학술대회 Vol.1992 No.6

CT-26 선암을 접종한 마우스에서 Iodine-131-Iodomisonidazole 의 생체분포 및 종양저산소증의 영상화

Yang, David J,Kim, E Edmund,김혜원,김창근,윤권하,김현정,정선관,노병석,Lee, Hyun-Chul 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

urpose: Misonidazole is a radiosensitizer that binds in hypoxic cells. The purpose of this study was to find out the feasibility of I-131-Iodomisonidazole (IMISO) for imaging of tumor hypoxia. Materials and Methods: Tosyl precursor was dissolved in acetonitrile and I-131-NaI was added to synthesize IMISO. Balb/c mice inoculated with CT-26 adenocarcinoma were injected with IMISO. Mice were sacrificed at 1,2,4,24 hr and % of injected dose per gram of tissue (%ID/g) was determined. For scintigraphy and MRI, mouse bearing CT-26 adenocarcinoma was administered with IMISO and imaging was performed 4 hr after. Then, mouse body was fixed and microtomized slice was placed on radiographic film for autoradiography. Results: %ID/g of tumor was 1.64 (1h), 0.98 (2h), 0.85 (4h) and 0.20 (24h), respectively. At 24h, %ID/g of tumor was higher than that of all other tissues except thyroid. Tumor to muscle ratio increased with time and tumor to blood ratio also increased with time and reached 1.53 at 24 hr. On autoradiogram, tumor was well visualized as an increased activity in central hypoxic area of the tumor which corresponds to the area of high signal intensity on T2-weighted MR image. On scintigraphy, tumor uptake was visualized. Conclusion: This results suggest that IMISO may have a potential for tumor hypoxia imaging in mouse model. However, further study is needed to improve it's localization in tumor tissue and to achieve acceptable images of tumor hypoxia.

Kidney Toxicity Induced by 13 Weeks Exposure to the Fruiting Body of Paecilomyces sinclairii in Rats

Jeong, Mi-Hye,Kim, Young-Won,Min, Jeong-Ran,Kwon, Min,Han, Beom-Suk,Kim, Jeong-Gyu,Jeong, Sang-Hee Korean Society of ToxicologyKorea Environmental Mu 2012 Toxicological Research Vol.28 No.3

Paecilomyces sinclairiis (PS) is known as a functional food or human health supplement. However concerns have been raised about its kidney toxicity. This study was performed to investigate the kidney toxicity of PS by 13 week-oral administration to rats. Blood urea nitrogen (BUN), serum creatinine, and kidney damage biomarkers including beta-2-microglobulin (${\beta}2m$), glutathione S-transferase alpha (GST-${\alpha}$), kidney injury molecule 1 (KIM-1), tissue inhibitor of matrix metalloproteinase 1 (TIMP-1), vascular endothelial growth factor (VEGF), calbindin, clusterin, cystatin C, neutrophil gelatinase-associated lipocalin (NGAL) and osteopontin were measured during or after the treatment of PS. BUN, creatinine and kidney damage biomarkers in serum were not changed by PS. However, kidney cell karyomegaly and tubular hypertrophy were observed dose-dependently with higher severity in males. KIM-1, TIMP-1 and osteopontin in kidney and urine were increased dose dependently in male or at the highest dose in female rats. Increased urinary osteopontin by PS was not recovered at 2 weeks of post-exposure in both genders. Cystatin C in kidney was decreased at all treatment groups but inversely increased in urine. The changes in kidney damage biomarkers were more remarkable in male than female rats. These data indicate that the PS may provoke renal cell damage and glomerular filtration dysfunction in rats with histopathological lesions and change of kidney damage biomarkers in kidney or urine. Kidney and urinary KIM-1 and cystatin C were the most marked indicators, while kidney weight, BUN and creatinine and kidney damage biomarkers in serum were not influenced.

불소배합 음용수와 불화우유 섭취에 의한 백서치아 탈회 억제효과 비교

송근배,송재상,김혜영,김정숙,김지영 경북대학교 병원 2002 경북대학교병원의학연구소논문집 Vol.6 No.1

The purpose of this study was to investigate the inhibitory effect of fluoride in the water and milk on tooth enamel dissolution by commercial beverages. 3 weekold 60 female sprague-Dawley strain were divided into four groups and given the following dosage of fluoride in the drinking water:0,1,5 and 50ppm for six and twelve weeks ad libitum. Upper incisors were prepared for specimen with low speed dental disc.The slabs of each incisors were embedded in unsaturated polyester,polished with #1,200 silicon carbide paper and aluminisilicate powder.Three kinds of beverage were selected for test medium and enamel slabs of rat incisors were dipped for 60 and 120 minutes in each beverage.Surface microhardness was examined before and after dissolution with beverage. All collected data were analyzed using the SAS package.Differences between groups were compared by the one-way ANOVA,Duncan's multiple range test and ANCOVA procedures. Corresponding p-values were considered significant at the values less than 0.05. The obtained results were as follows: 1. Surface microhardness was significantly increased both 6 and 12 weeks groups compared with control group. Surface microhardness of high fluoride groups were also proportionally increased with increasing concentration of fluoride both in the water and milk. 2. There were significant differences of inhibitory effect of surface microhardness after 60 and 120 minutes emersion periods,and both at 6 and 12 weeks group in the veverage B and C,but not appeared in the beverage A. 3. The inhibitory effect of enamel dissolution was higher in the 12 weeks group than 6 weeks group both at the water fluoridation and milk fluoridation. 4. The differences of micro hardness between before and after emersion in the beverages were larger in the milk fluoridation groups than water fluoridation groups.

간호학생이 지각한 사회적 지지와 정신건강과의 관계

김혜숙 성신간호대학 (성신간호전문대학) 1999 논문집 Vol.8 No.-

This study was designed to identify the relationship between the perceived social support and mental health of nursing students. The purposes of this study were as follows: 1. To explore the perceived social support and mental health of nursing students. 2. To investigate the relationship between the perceived social support and the level of mental health. 3. To test for significant difference in the perceived social support and the level of mental health in relation to general characteristics. The subjects of this study were 248 junior college nursing students. The data were collected during the period from November 9 to 13, 1998. The instruments for this study were the Generally Perceived Social Support Scale developed by Dr. Park, Ji-won and the Simplified Mental Diagnostic Test developed by Prof. Lee, Hun-ku. The results of the study were follows: 1. The mean score for the perceived social support scale was 91.33. 2. The mean score for the level of mental health was 93.81. 3. The relationship between the perceived social support and the level of mental health revealed a significant correlation(r=.4670, p=.000). 4. The relationships between four types of the indirectly perceived social support and the level of mental health were analyzed. The emotional support(r=.2433, p=.000), the informational support(r=.2799, p=.000), material support(r=.1905, P=.001) and the appraisal support(r=.2164, P=.000) were significantly related to the level of mental health. 5. The results from the tests for the degree of social support and the level of mental health according to the subjects' general characteristics showed that there were significant differences with home environment, the degree of satisfaction in major subjects and whether the student participated in extracurricular group activities or not. In conclusion, this study showed that social support is an important factor that can improve the level of mental health in nursing students. Further multidimensional study is needs on how to improve the mental health in nursing students through the social support.

A rare case of extensive papillary muscle calcification in senile cardiac calcification syndrome

김은진;송봉근;강민호;손형래;홍수민;박동원;허승혜;김계연;최석구 인제대학교 2011 仁濟醫學 Vol.32 No.-

광범위 유두근 석회화는 흔하지 앉으며, 원인과 임상적 중요성에 관한 문헌만 드물게 찾아볼 수 있다. 반면에 작은 석회 침착은 노인에서 흔하며 심장 첨부에 주로 나타난다. 유두근 석회화는 관상동맥질환, 확장성 심근병증, 승모관 질환, 고칼슘혈증, 그리고 말기신부전에서 인산칼슘의 중가와 연관성이 있다. 저자는 심장초옴파와 MDCT를 통해 진단된 전외측 유두근의 광범위 석회화의 드문 사례가 있어 보고한다.

두개저 및 하악골에서 최대 사춘기 급성장

김혜숙,권오원 대한치과교정학회 1993 대한치과교정학회지 Vol.23 No.4

The purpose of this study was to investigate not only the variability in the timing and amount of the maximum pubertal spurt in cranial base and mandible, but also its interrelationship with the timing of peak height velocity. This study was carried out by analysing biannual serial lateral cephalometric radiographs of twenty-six males and twenty-one females who were taken from 8.5years to 16.5years old of mean age, according to the established land-marks and linear measurements. The results of this study were summarized as follows. 1. Prevalance fo the maximum growth spurt more than 80 percentage was occurred earlier in all measurements of cranial base and mandible, except posterior cranial base length in the female. 2. In all measurements of cranial base and mandible, the maximum spurt was occurred earlier in the female than the male while it was greater in male in all measurements except ramal height. 3. In body height measurement, the peak height velocity was occurred 2 years earlier for the female(11.0 years old) than the male(13.0 years old). 4. The timing of maximum spurt in anterior cranial base length and total mandibular length in both sexes and ramal height in the female were coincided with PHV. The maximum spurt was occurred in both sexes in all measurements 2 years before or after PHV, except mandibular body length and posterior cranial base length the in female. 5. In all ages, there was significant correlation between th etotal mandibular length and ramal height, and was also correlation between total cranial base length and anterior cranial base length(P<0.05). However, there was no significant correlation between the ramal height and mandibular body length. In addition, there was also no any correlation between the anterior cranial base length and posterior cranial base length in all ages(P>0.05).

한방재료를 첨가한 타조 추출액의 영양학적 특성에 관한 연구

김애정,여정숙,장준혁,우경자,김혜진 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.3

This study was undertaken to analyze chemical composition, macro- and micro-mineral contents of ostrich bone with flesh meat (BF), ostrich bone with flesh meat with herb medicine (BFH) and ostrich bone with internal organs (BI). Crude fat of the BFH was lower, but crude protein and crude ash of the BFH were significantly higher than those of the BF and the Bl. Among the minerals, Ca, P. Mg, Fe, Cu, Zn content of the BFH were significantly higher than the content in the BF and the BE The minerals, Ph, Cd and As were not detected in ostrich and herb medicine extracts. From the sensory, test of ostrich and herb medicine, the preferences were in the following order: ostrich bone with flesh meat with herb medicine (BFH), ostrich bone with flesh meat (BF), and ostrich bone with internal organs (BI) in extracts.