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- 저자 : Hailing Liu (검색결과 10 건)
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Liu Hailing,Zhang Jing,Liu Li,Lian Guoli,Shi Ruiming,Xu Man,Yang Juan,Liu Xiaohong 대한천식알레르기학회 2023 Allergy, Asthma & Immunology Research Vol.15 No.4
Purpose: Asthma is a common chronic inflammatory respiratory tract disease with high morbidity and mortality. The global trends in asthma burden remain poorly understood, and asthma incidence has increased during the worldwide coronavirus disease 2019 (COVID-19) pandemic. This study aimed to provide a comprehensive view of the global distribution of asthma burden and its attributable risk factors from 1990 to 2019. Methods: Based on the Global Burden of Disease Study 2019 Database, asthma incidence, deaths, disability-adjusted life years (DALYs), the corresponding age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), age-standardized DALY rate, and estimated annual percentage change were analyzed according to age, sex, sociodemographic index (SDI) quintiles, and locations. Risk factors contributing to asthma deaths and DALYs were also investigated. Results: Globally, the asthma incidence increased by 15%, but deaths and DALYs decreased. The corresponding ASIR, ASDR, and age-standardized DALY rate also decreased. The high SDI region had the highest ASIR, and the low SDI region had the highest ASDR. The ASDR and age-standardized DALY rate were negatively correlated with the SDI. The low-middle SDI region, particularly South Asia, showed the highest asthma-related deaths and DALYs. The incidence peak was under 9 years old, and more than 70% of all deaths occurred in the population over 60 years old. Smoking, occupational asthmagens, and a high body mass index were the main risk factors for asthma-related mortality and DALYs, and their distributions varied between sexes. Conclusions: Globally, the asthma incidence has increased since 1990. The greatest asthma burden is borne by the low-middle SDI region. The 2 groups that need special attention are those under 9 years old and those over 60 years old. Targeted strategies are needed to reduce the asthma burden based on geographic and sex-age characteristics. Our findings also provide a platform for further investigation into the asthma burden in the era of COVID-19.
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First-principles study of LiBaF3 crystals containing interstitial fluoride
Hailing Qiao,Tingyu Liu,Qiren Zhang,Fang Cheng,Xiuwen Zhou 한국물리학회 2010 Current Applied Physics Vol.10 No.5
The positions of the interstitial fluoride atoms in LiBaF3 crystal are simulated by GULP. It is found that the formation energy is low when interstitial fluoride atoms at the center of the edge of the cube formed by Ba ions. The electronic structures and absorption bands for the perfect LiBaF3 crystal and the LiBaF3 crystal containing interstitial fluoride have been calculated using density functional theory code CASTEP. It is predicted that the interstitial fluoride atom combine with a formal lattice fluoride ion forming H center causes the 320 nm absorption band.
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Luo Hailing,Xu Yongfeng,Zhang Yingjun,Zhang Xiaohong,Liu Kai 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
A total of 106 two month-old Nanjiang yellow goats (male were 32, female were 34 and castrated were 40) were divided into treatment group and control group to determine the growth performance. The treatment group was reared in grazing mode, experimental group was pastured with supplement feeding. The results showed that the body weight of male in experiment group was heavier by 9.82%(P<0.05), 11.87%(P<0.01), 16.91%(P<0.01) and 23.99%(P<0.05) than that in control group in 3,4,5 and 6 month-age. The body weight of female in experimental group was heavier by 11.54%(P<0.05), 13.79%(P<0.01), 17.47%(P<0.01) and 21.15%(P<0.01) than that in control group in 3,4,5 and 6 month-old. The body weight of castrator in experimental group was heavier by 1.58%, 1.99%, 13.08%(P<0.01) and 15.76%(P<0.01) than that in control group in 3,4,5 and 6 month-age. The daily increasing weight and body measurements of experimental group is improved more than control group, especially in 6 month-age.
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3D Holographic Image Recognition by Using Graphic Processing Unit
이정아,문인규,Hailing Liu,Faliu Yi 한국광학회 2011 Current Optics and Photonics Vol.15 No.3
In this paper we examine and compare the computational speeds of three-dimensional (3D) object recognition by use of digital holography based on central unit processing (CPU) and graphic processing unit (GPU)computing. The holographic fringe pattern of a 3D object is obtained using an in-line interferometry setup. The Fourier matched filters are applied to the complex image reconstructed from the holographic fringe pattern using a GPU chip for real-time 3D object recognition. It is shown that the computational speed of the 3D object recognition using GPU computing is significantly faster than that of the CPU computing. To the best of our knowledge, this is the first report on comparisons of the calculation time of the 3D object recognition based on the digital holography with CPU vs GPU computing.
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Zhenzhen Wang,Yong Chen,Hailing Luo,Xueliang Liu,Kun Liu 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.8
Fifty 3-month-old male Tan lambs (similar in body weight) were divided into 5 groups to investigate the effects of different restricted pasture grazing times and indoor supplementation on the productive performances and fatty acid composition of the intramuscular fat in growing lambs. The lambs grazed for different periods of time (12 h/d, 8 h/d, 4 h/d, 2 h/d, and 0 h) and received various amounts of supplementary feedings during the 120-day trial. Pasture dry matter intake (DMI), total DMI, average daily gains and the live body weights of the lambs were measured during the experiment. The animals were slaughtered at the end of the study, their carcass traits were measured, and their longissimus dorsi muscles were sampled to analyze the intramuscular fat (IMF) content and fatty acid profiles. The results indicated that the different durations of grazing and supplementary feedings affected the animal performances and the composition of fatty acids. Grazing for 8 h/d or 2 h/d with the corresponding supplementary concentrate resulted in lambs with higher body weights, carcass weights and IMF contents. Lambs with longer grazing times and less concentrate accumulated more healthy fatty acids such as conjugated linoleic acid and n-3 polyunsaturated fatty acid and had higher n-3/n-6 ratios. Overall, a grazing allowance of 8 h/d and the corresponding concentrate was recommended to maintain a high quantity and quality of lamb meat.
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Chen, Yong,Luo, Hailing,Liu, Xueliang,Wang, Zhenzhen,Zhang, Yuwei,Liu, Kun,Jiao, Lijuan,Chang, Yanfei,Zuo, Zhaoyun Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.5
To investigate the effect of restricted grazing time on behavior of Tan sheep on desert steppe, forty 4-months old male Tan sheep with an original body weight (BW) of $15.62{\pm}0.33$ kg were randomly allocated to 4 grazing groups which corresponded to 4 different restricted grazing time treatments of 2 h/d (G2), 4 h/d (G4), 8 h/d (G8) and 12 h/d (G12) access to pasture. The restricted grazing times had a significant impact on intake time, resting time, ruminating time, bite rate and movement. As the grazing time decreased, the proportion of time spent on intake, bite rate and grazing velocity significantly (p<0.05) increased, but resting and ruminating time clearly (p<0.05) decreased. The grazing months mainly depicted effect on intake time and grazing velocity. In conclusion, by varying their foraging behavior, Tan sheep could improve grazing efficiency to adapt well to the time-limited grazing circumstance.
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Dominant genera of cyanobacteria in Lake Taihu and their relationships with environmental factors
Lijun Feng,Shiyou Liu,Wenxian Wu,Jiawen Ma,Pei Li,Hailing Xu,Na Li,Yaoyu Feng 한국미생물학회 2016 The journal of microbiology Vol.54 No.7
Cyanobacterial blooms in freshwaters have become one of the most widespread of environmental problems and threaten water resources worldwide. Previous studies on cyanobacteria in Lake Taihu often collected samples from one site (like Meiliang Bay or Zhushan Bay) and focused on the variation in patterns or abundance of Microcystis during the blooming season. However, the distribution of cyanobacteria in Lake Taihu shows differing pattern in various seasons. In this study, water samples were collected monthly for one year at five sites in Lake Taihu with different trophic status and a physicochemical analysis and denaturing gradient gel electrophoresis (DGGE) were conducted. DGGE fingerprint analysis showed that Microcystis (7/35 bands) and Synechococcus (12/35 bands) were the two most dominant genera present during the study period at all five sites. Cyanobium (3/35 bands) was the third most common genus which has seldom been previously reported in Lake Taihu. Redundancy analysis (RDA) indicated that the cyanobacterial community structure was significantly correlated with NO3 --N, CODMn, and NH4 +-N in the winter and spring, whereas it was correlated with water temperature in the summer and autumn. Limiting the nutrient input (especially of N and C loading) in Lake Taihu would be a key factor in controlling the growth of different genera of cyanobacteria.
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Rui Zou,Xiao Zhou,Hailing Liu,Peng Wang,Fan Xia,Liqing Kang,Lei Yu,Depei Wu,Zhengming Jin,Changju Qu 대한암학회 2023 Cancer Research and Treatment Vol.55 No.4
Primary central nervous system lymphoma (PCNSL) is a rare and aggressive non-Hodgkin’s lymphoma that affects the brain, eyes, cerebrospinal fluid, or spinal cord without systemic involvement. The outcome of patients with PCNSL is worse compared to patients with systemic diffuse large B-cell lymphoma. Given potential mortality associated with severe immune effector cell-associated neurotoxicity syndrome (ICANS), patients with PCNSL have been excluded from most clinical trials involving chimeric antigen receptor T-cell (CAR-T) therapy initially. Here, we report for the first time to apply decitabine-primed tandem CD19/CD22 dual-targeted CAR-T therapy with programmed cell death-1 (PD-1) and Bruton’s tyrosine kinase (BTK) inhibitors maintenance in one patient with multiline-resistant refractory PCNSL and the patient has maintained complete remission (CR) for a 35-month follow-up period. This case represents the first successful treatment of multiline resistant refractory PCNSL with long-term CR and without inducing ICANS under tandem CD19/CD22 bispecific CAR-T therapy followed by maintenance therapy with PD-1 and BTK inhibitors. This study shows tremendous potential in the treatment of PCNSL and offers a look toward ongoing clinical studies.
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Wang, Zhenzhen,Chen, Yong,Luo, Hailing,Liu, Xueliang,Liu, Kun Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.8
Fifty 3-month-old male Tan lambs (similar in body weight) were divided into 5 groups to investigate the effects of different restricted pasture grazing times and indoor supplementation on the productive performances and fatty acid composition of the intramuscular fat in growing lambs. The lambs grazed for different periods of time (12 h/d, 8 h/d, 4 h/d, 2 h/d, and 0 h) and received various amounts of supplementary feedings during the 120-day trial. Pasture dry matter intake (DMI), total DMI, average daily gains and the live body weights of the lambs were measured during the experiment. The animals were slaughtered at the end of the study, their carcass traits were measured, and their longissimus dorsi muscles were sampled to analyze the intramuscular fat (IMF) content and fatty acid profiles. The results indicated that the different durations of grazing and supplementary feedings affected the animal performances and the composition of fatty acids. Grazing for 8 h/d or 2 h/d with the corresponding supplementary concentrate resulted in lambs with higher body weights, carcass weights and IMF contents. Lambs with longer grazing times and less concentrate accumulated more healthy fatty acids such as conjugated linoleic acid and n-3 polyunsaturated fatty acid and had higher n-3/n-6 ratios. Overall, a grazing allowance of 8 h/d and the corresponding concentrate was recommended to maintain a high quantity and quality of lamb meat.
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