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      • Treadmill 運動負荷後 精神的 訓練方法이 恢復期 心搏數와 血中젖산 濃度에 미치는 影響

        李金海 조선대학교 스포츠과학연구소 1994 스포츠科學硏究 Vol.6 No.-

        The purpose of this study was to investigate the effect of treadmill exercise on resting heart rate and blood lactate response to mental practice, and to explore the restored patterns during recovery post exercise. This study employed 2O field hockey player of women, they were divided into experimental group(10) and control group(10). All experimental or control were performed in the same condition between 10:00 and 12:00 AM, between 15:00 and 18:00 PM. Cardiovascular function and blood sample(lactate) were collected at 60min before exercise(Re), immediately after exercise(Ro), at 5min(R_5) and 10min(R10), 20min(R_20) during recovery post exercise. All date were expressed as Mean and S.D. From the statistical evaluation of data and review of related previous studies conclusions may be made as follows; 1. Resting heart rate in experiment groups the apply of mental practice in during recovery is tended to decrease, and the difference of was statistically significantly ( P<5). 2. Blood lactate response in experiment groups the apply of mental practice in during recovery is tended to decrease, and the difference of was statistically significantly(P<5)

      • RTT에 가중치를 적용한 Snoop 알고리즘 성능 개선

        금승한,김태훈,박혜련,이기현 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

        In this paper, we propose the enhanced algorithm to cope with the issue which shows that short connections lend to lose to long connections in their competition for bandwidth in the wireless internet environment. This is because TCP is originally evolving in wired environment and short connections don’t know the traffic information, and therefore they are doomed to be less competitive due to the conservative nature of the TCP congestion control algorithm. Inspired by the Snoop algorithm, we proposed an enhanced algorithm to give an improved performance by adapting the weight in RTT estimation of the Snoop algorithm, so that the fairness is applied in the wirelss internet environment.

      • 초산모와 경산모에 있어서 돌보는 방법의 구별능력 비교

        이혜경,김금숙 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.2

        The purpose of this study was to evaluate the differentiate of baby attitude and mothering method by parity. 60 primiparous and multiparous women were examined in this study. The data were analized statistically by means of t-test. The finding of these study could be summerized as follows: 1. There was no significant difference in baby attitudy score on primiparous 33.1, multiparous 34.1. 2. There was no significant difference in score of BITS on primiparous women versus multiparous women in the 4 month baby; primiparous 110.5, multiparous 121.07. 3. There was significant difference in score of BITS on primiparous women versus multiparous-women in the 8 month baby; primiparous 112.27, multiparous 128.83(P<0.02). 4. There was significant difference n score of BITS on primiparous women versus multiparous women in the 4 month baby and 8 month baby; primiparous 111.30, multiparous 124.52(P<0.05). 5. There was no significant difference in Factor I score of BITS on primiparous women versus multiparous women in the 4 month baby; primiparous 10.39, multiparous 11.60. 6. There was no significant difference in Factor I score of BITS on primiparous women versus multiparous women in the 4 month baby; primiparous 12.27, multiparous 12.00. 7. There was no significant difference in Factor I score of BITS on primiparous women versus multiparous women in the 4 month baby; primiparous 18.56, multiparous 18.00. 8. There was no significant difference in Factor I score of BITS on primiparous women versus multiparous women in the 4 month baby; primiparous 17.40, multiparous 18.92.

      • KCI등재

        과민성 장 증후군의 증상 경감을 위한 비약물적 접근 고찰

        최명애,김금순,안경주,채영란,최정안,홍해숙,박미정,이경숙,신기수,정재심 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.2

        There have been many trials of clinical efficacy of multicomponent and single component treatments for irritable bowel syndrome(IBS). We reviewed effects of non phamacological treatments in the IBS. Though the efficacy of multi-component approaches was unclear, several results suggest that cognitive behavioral therapy was effective in improving gastrointestinal symptoms of IBS. As a single component, cognitive therapy and relaxation with or without biofeedback could improve the symptoms and psychological health of IBS patients. Yoga, meditation, self-help information and hypnotherapy could be applicable to IBS.

      • Urea Docomposition and its turnover Time in Euphotic Layer of Reservoires in the North Han Hiver System

        삼전촌서좌무,조규송,홍사욱,이해금 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-

        The in situ rate of urea decomposition was measured in the euphotic layer of three reservoirs located in the North Han River System. The urea decomposition rates (as sum of incorporation rate of urea carbon into particulate matter and CO_(2) liberation rate into water from urea) in surface waters were 12, 80 and 54 μmol urea · m^(-3) day^(-I), in Lake Soyang, Lake Chuncheon and Lake Euiam. The greater part of urea decomposition took place with the C0_(2) liberation into water. High rates of urea carbo incorporation were obtained at surface layer, while low rates were found in lower layer and the dark bottles. The decomposition rate of urea, the carbon incorporation rate, and the CO_(2) liberation rate decreased with depth. The vertical distributions of the urea decomposition rate showed similar patterns to those of photosynthesis. The turnover rates of urea in the three reservoirs were calculated respectively as 41,6.1 and 3.4 days at the surface, and the values increased with depth. 북한강수계 3개 인공호수의 생산층에 있어서 현장법으로 요소 분해속도를 측정했다. 요소분해속도(요소에서 유래도는 탄소가 수중생물로 흡수되는 량과 이산화탄소로서 수중에 방출되는 량의 합)는 소양호, 춘천호 및 의암호의 표층수에서 각각 12, 80, 54μmol Urea m^(-3)·day^(-1)였다. 요소 분해는 대부분이 이산화탄소 형태로 수중에 방출된다. 요소태탄소의 흡수속도는 표층에서 높은 값이 관찰됐으나 생산층의 하층 및 암조건에서는 낮았다. 요소분해속도, 요소태탄소의 흡수속도 및 이산화탄소의 방출 속도는 깊이에 따라 감소됐다. 요소분해속도와 광합성의 수직분포는 유사하였다. 각 호수의 표층수에 있어서 회전시간은 소양호, 춘천호 및 아ㅢ암호에서 4.1, 6.1 및 3.41일로 계산되며 이 값은 깊이에 따라 증가됐다.

      • SCIESCOPUSKCI등재

        부인과 다발성 원발 악성종양의 임상적 고찰

        이철호,이정재,남계현,이권해,유백근,주명찬,이금원 대한부인종양 콜포스코피학회 1993 Journal of Gynecologic Oncology Vol.4 No.1

        Sixteen multiple primary carcmomas were found in 674 patients with gynecologic malignancies who were treated in our departiment from l980 to 1992. Cases with possible metastasis or recurrence were not included in this study, The incidence of rnultiple primary carcinomas in gynecologic rnalignancies was 2.1%, Multiple primary carcinomas were encountered in 2.4% of 674 cervical cancers, 1.4% of 73 ovarian cancers respectively. The most frequent sites of uther cancers were seen in the stomach(5/16) and lung(3/l6).

      • 자궁경부암 환자의 근치수술에 대한 임상적 고찰

        이권해,김성호,이중구,이금원,이철호,주명찬,이정재,남계현 순천향대학교 1993 논문집 Vol.16 No.2

        From 1986 through 1990, 71 patients with carcinoma of the uterine cervix were treated primarily with surgery at Soonchunhyang Hospital, Seoul, Korea. The purpose of this report was to analyze the clinical data and survival rate of these patients. 1. The clinical stages of 71 patients who had operation were as followed : Stage ?? 9 cases(12.6%) ; Stage ?? 48 cases(67.8%); Stage ?? 9 cases(12.6%) ; and ?? 3 cases(7.0%). 2. The survival rates by stages in confirmed patients by followed up were Stage ??100%; Stage ?? 83.6%; Stage ?? 88.9%; Stage ?? 100%. 3. The survival rates by histopathologic subtype were Squamous cell carcinoma, 87.2%; Adenocarcinoma, 100%. 4. The survival rate of positive lymph nodal metastasis was 84.6% and one of negative lymph nodal metastasis was 91.3%. 5. The survival rate of operation only group was 91.6%, and one of operation plus adjuvant radiation therapy group was 90.0%.

      • KCI등재후보

        Clinical Study of Diffusion Hypoxia in Early Period after Nitrous Oxide Anesthesia

        Hae Keum Kil,Won Oak Kim,Sung Jin Lee,Woo Kyung Lee Korean Society of Critical Care Medicine 1998 Acute and Critical Care Vol.13 No.1

        Introduction: Anesthesiologists have been aware of the dangers of diffusion hypoxia in the early postoperative period after nitrous oxide anesthesia, but it was suggested of a little clinical significance in healthy patients. Goal of this study is to re-evaluate the possibility of diffusion hypoxia. METHODS: Eighty patients who were scheduled for vitrectomy were allocated to two groups by normal and abnormal chest X-ray findings and each group was divided into two subgroups by N2O concentration (1-a, 2-a; 50%, 1-b, 2-b; 60%). One and half hours after anesthesia, end-tidal alveolar concentration of oxygen (et-O2), N2O (et-N2O), and PaO2 were measured for 10 minutes after the inspired gases were changed to room air 2 L/minute with controlled ventilation in group 1-a. Those parameters were re-measured after re-administration of O2 and N2O of 50% of each for an hour and the inpired gases were changed to room air again. RESULTS: In group 1-a, there was no significant differences of et-N2O and PaO2 after 5 minutes by air flow. And there was no differences of et-N2O and PaO2 between group 1-a and 1-b by et-N2O after 4 minutes. In group 1-b, PaO2 was in normal range at 10 minutes after, although et-O2 was decreased to 14.9%. However, group 2-b showed peripheral arterial saturation lower than 96% after 6 minutes and mild hypoxemia (PaO2 75.3 mmHg) at 10 minutes. CONCLUSIONS: We suggest that hypoxemic episode during spontaneous breathing of room air in early postoperative period after nitrous oxide anesthesia may be occur due to decreased ventilatory function rather than diffusion of nitrous oxide. However, in patients with minimal abnormal chest X-ray findings even without clinical symptoms, it would be better to avoid high concentration of nitrous oxide.

      • 생명공학의약품의 약동학 시험 지침 개발 연구

        이혜원 ( Hae Won Lee ),윤영란 ( Mi Sun Lim ),임미선 ( Sook Jin Seong ),성숙진 ( Joo Mi Lee ),이주미 ( Sung Min Park ),박성민 ( Keum Han Noh ),노금한 ( Sung Ho Park ),박성호 ( Eun Jung Kim ),김은정 ( Won Ku Kang ),강원구 ( Young Ra 영남대학교 약품개발연구소 2012 영남대학교 약품개발연구소 연구업적집 Vol.22 No.0

        Modem biologics are biotechnology-derived therapeutics, ineluding recombinant therapeutie proteins like monoclonal antibodies, cytokines and tissue growth factors. Although the pharmacokinetics of therapeutic biologic should be evalu-ated based on the same general principles as small molecules, careful considerations should be given to bioanalyties and phannacokinetics when designing pharmaeokinetic studies of biologics during their drug development, due to their dif-feren physicochemical properties compared with small molecules. The aim of this study was to develop draft guid-ance on pharmacokinetic studies of therapeutic biologics in clinical studies. All the elements outlined in the current Food and Drug. Administration (FDA), European Medicinal Agency (EMEA), and International Conference on Hannom-isation (ICH) guidelines and regulations, and the related literatures previously published were searched and evaluated. In this drall guidance, the specitic problems to the pharmacokinetics of therapeutic biologics that need special consideration sideration during drug development process were addressed, and differences in pharmacokinetic characteristics between biologics and small molecules affecting the content of the development programme were presented.

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