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Scale 제어를 통한 제지공정 안정화 및 용수 절감 방안
권오철,박지혜,조병묵,오정수 동국대학교 생명자원과학대학 연습림 2000 연습림논문집 Vol.- No.6
Recently, many paper industries are trying to recycle the under of processing for reserving the environment and saving the water. Because of the decrease of the lord of waste water, the process water concentrate the in the substance which is create the scale in the process and then, these factor cause the decrease of qualify of products and need the cost for cleaning the machine. In this study, through the analysis of process water for each part, we examine the degree of stability index and saturation index. We expect the scale in the system. We also examine the change of process water to stabilize the quality of products and work.
제지용 섬유의 Carboxymethyl화 및 Carbamoylethyl화에 의한 sheet의 습윤강도 향상
정명준,권오철,조병묵,오정수 동국대학교 생명자원과학대학 연습림 2000 연습림논문집 Vol.- No.6
Paper has been an essential part of our civilization for at least two thousand years and we can get various functional paper given by the treatment of coating, laminating, blending and addition of chemicals. Above all, wet strength paper is an important group of other grade paper. Certain paper require a wet strength in order to maintain their properties under wet or humidity conditions. For the purpose of improving the wet strength properties of paper, cellulose fiber was modified by the process of carbamoylethylation and carboxy- methylation. We have the carbamoylethylation of cellulose fiber reacted with acryl- amide in alkali catalyst and carboxymethylation of cellulose fiber reacted with mono- chloroacetic acid in alkali catalyst. The N-chlorocarbamoylethylated sheet and combined sheet of carboxymethylated and carbamoylethylated cellulose fiber more effect than untreated sheet in dry strength. As for folding endurance, the combination of carboxymethylated cellulose fiber and carbamoylethylated cellulose fiber sheet were more effective than other modified fibers. The combination of carboxymethylated cellulose fiber and carbamoylethylated cellulose fiber sheet has some effect on wet tensile strength, but this sheet it less effective than N-chlorocarbamoylethylated sheet.
박지혜,권오철,조병묵,오정수 동국대학교 생명자원과학대학 연습림 2000 연습림논문집 Vol.- No.6
Cationic dispersed rosin sizes are the newest of the dispersed rosin sizes. Cationic dispersed rosin sizes are self-retaining of anionic fiber pulp. This means that alum is not required for size retention, therefore it is uniform over a wider range than with traditional dispersed rosin sizes. In this study, sizing effect and retention mechanism under neutral condition were studied on the basis of handsheets prepared under various conditions.
Ryu, Chung Heon,Park, Sang-Hoon,Park, Soon A,Kim, Seong Muk,Lim, Jung Yeon,Jeong, Chang Hyun,Yoon, Wan-Soo,Oh, Won-il,Sung, Young Chul,Jeun, Sin-Soo Mary Ann Liebert 2011 Human gene therapy Vol.22 No.6
<P>Clinical trials of gene therapy using a viral delivery system for glioma have been limited. Recently, gene therapy using stem cells as the vehicles for delivery of therapeutic agents has emerged as a new treatment strategy for malignant brain tumors. In this study, we used human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) as delivery vehicles with glioma-targeting capabilities, and modified interleukin-12 (IL-12p40N220Q; IL-12M) as a novel therapeutic gene. We also engineered UCB-MSCs to secret IL-12M (UCB-MSC-IL12M) via tetrameric cell-permeable peptide (4HP4)-mediated adenoviral transduction. We confirmed the migratory capacity of UCB-MSC-IL12M toward GL26 mouse glioma cells by an in vitro migration assay and in vivo injection of UCB-MSC-IL12M into the ipsilateral hemisphere of implanted gliomas in C57BL/6 mice. In vivo efficacy experiments showed that intratumoral injection of UCB-MSC-IL12M significantly inhibited tumor growth and prolonged the survival of glioma-bearing mice compared with control mice. Antitumor effects were associated with increased local IL-12M levels, followed by interferon-γ secretion and T-cell infiltration in intracranial gliomas, as well as antiangiogenesis. Interestingly, tumor-free mice after UCB-MSC-IL12M treatment were resistant to ipsilateral and contralateral tumor rechallenge, which was closely associated with tumor-specific long-term T-cell immunity. Thus, our results provide the rationale for designing novel experimental protocols to induce long-term antitumor immunity against intracranial gliomas using UCB-MSCs as an effective delivery vehicle for therapeutic cytokines including IL-12M.</P>
저용량 스트렙토조토신 유발 당뇨병 생쥐에서 인슐린 및 비타민 E 투여가 췌장 소도세포의 세포자연사(Apoptosis)에 미치는 영향
김상진,이응석,김난희,김용현,최동섭,백세현,이민철,오정헌,최경묵 대한당뇨병학회 1999 Diabetes and Metabolism Journal Vol.23 No.6
Background : Type 1 diabetes mellitus results from irreversible loss of β cells in pancreatic islet. It is generally known that abnormal MHC expression and interaction of variable cytokines play a role in β cell death, but the precise mechanism of β cell death is unknown. Apoptosis is a physiological form of cell death and can play an important role in β cell death in experimental diabetic animal models. Thus, in insulin and vitamin E treated LDSD mice and streptozotocin treated control mice. We attempted to comparing the levels of blood glucose (BG), the degree of insulitis, and number of apoptotic cells. Our study goal was to understand inhibition of apoptosis which thought to play an important mechanism in reducing the degree of hyperglycemia and insulitis. Methods: In 3 LDSD mice groups (group 1: control group with streptozotocin only, group 2: streptozotocin plus insulin, group 3: streptozotocin plus vitamin E), the effects of insulin and vitamin E on the blood glucose levels and the degree of insulitis were evaluated. The number of apoptotic cells of pancreatic islet was compared using double staining immunohistochemical method. Results : The levels of BG, degree of insulitis and the rate of apoptosis of pancreatic islet cells were decreased in insulin and vitamin E treated groups when compared to the control group. There was no difference in number of apoptotic cells between insulin and vitamin E treated group, but levels of BG and degree of insulitis were higher in vitamin E treated group than insulin treated group as time elapsed. Conclusion : Insulin and vitamin E can decrease the elevation of BG and the degree of insulitis via inhibition of apoptosis in LDSD mice.