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Chang-Won Im,Wan-Kyu Lee 한국예방수의학회 2021 예방수의학회지 Vol.45 No.3
The abnormal meat could caused by abscess, fibrosis and granuloma in the region of the neck by the adverse effect of foot-and-mouth disease (FMD) vaccination practice for Korean swine. After FMD vaccination was implemented in 2010, the number of incidences of abnormal meat has been increasing. In this study, it was evaluated whether needless intradermal injection (NII) of FMD vaccine reduces abnormal meat at the injection site in comparison to conventional intramuscular injection (IM). In addition, the onset of humoral immunity was analyzed in order to see if NII of this vaccine is able to mount comparable antibody response with IM. This study was carried out in four Korean pig farms. The O-type FMD vaccine was implemented via NII at three farms and the control group was vaccinated via IM. Antibody titers were compared from the serum samples taken from 10 random pigs at age of 8, 12, 16 and 22~24 weeks of age. The O+A type FMD vaccine was also compared with the same protocol. When test animals were slaughtered, incidence, type and size of abnormal meat were recorded. The results of this study showed that the antibody titers between intradermal and intramuscular group were similar but a significant difference in the incidence of abnormal meat formation was observed between two groups (p < 0.05). In summary, needless intradermal injection of FMD vaccination was proven to be effective for the onset of humoral immunity and reducing abnormal meat formation.
농촌지역 여성고령자의 현미덤벨체조가 체조성, 체력 및 식습관에 미치는 영향
이기철 ( Lee Gi Cheol ),정창주 ( Jeong Chang Ju ),손기수 ( Son Gi Su ),우임수 ( U Im Su ),이원경 ( Lee Won Gyeong ),공무현 ( Gong Mu Hyeon ),이수천 ( Lee Su Cheon ) 한국운동영양학회 2003 Physical Activity and Nutrition (Phys Act Nutr) Vol.7 No.2
The present study evaluated the possibility of dumbbell exercise as to improve the physical fitness and the health starus of old people in rural area. Although eighty seven volunteers of old women (over 64) living in Seonsan, Gumi city were subjected, twenty of them were attended the whole program for 6 months and the data from the twenty was analysed in this study. The results were drawn out from comparison of the body constitutuion, the physical strength, the medical aspectrs, and the questionaires of before and after this program. They showed increased physical fithess tested by grip strength (left), bar gripping reaction time, standing trunk flexibility, on foot standing test through dumbbell exercise for 6 months. Questionaire revealed the betterment of dietary pattem during this program. In the light of in these results, it is possible to conclude that dumbbell exercise had improved the basic physical condition and the health status through the increasement of physical fitness and dietary pattem change. Therefore, dumbbell exercise would be a useful program for the old people in reual area to improved their health status.
A preliminary study in melasma following INMODE forma procedure
( Soon-hyo Kwon ),( Je-byeong Chae ),( Jung-won Shin ),( Jung-im Na ),( Chang-hun Huh ),( Kyoung-chan Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Melasma is a common hypermelanosis that frequently appears on the face. In recent studies, it is suggested that dermal structural alteration, including solar elastosis and basement membrane disruption, may have an important role in the pathogenesis of melasma. Forma device (InMode Inc, Richmond Hill, ON, Canada, North America) is a radiofrequency dermal heating device used on facial wrinkles and rhytides. Objectives: The aim of this study was to evaluate the effects of Forma device on melasma in a small group of volunteers. Methods: All volunteers were treated 4 times at 3 weeks intervals. Every visit, melanin index and erythema index was measured to assess the improvement in hyperpigmentation and erythema. Clinical photos were evaluated to estimate the degree of skin changes. Results: Clinical and instrumental evaluation showed that melasma improved after INMODE forma treatment. Conclusion: We suggest that treatment with Forma device may have beneficial effects on melasma by dermal remodeling and direct heat delivery on melanocytes.
우황청심원 관련 최근 연구 동향 : 국내 논문에 대한 고찰
이제원,백경민,백영두,임은영,장우석,전우현,정인권,Lee, Je-Won,Baek, Kyung-Min,Baek, Young-Doo,Im, Eun-Young,Chang, Woo-Seok,Cheon, Woo-Hyun,Chung, In-Kwon 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.4
Objectives : Woohwangchungsim-won has been used for acute diseases such as cerebrovascular disease (stroke), heart disease. The aim of this study was to determine the effects, significance & necessity of Woohwangchungsim-won in acute stages of these disease by reviewing Korean articles about Woohwangchungsim-won. Methods : Article searches were performed on 8 major Korean web article search engine from January 1980 to August 2010. There were no restrictions on the types of publication, including grey articles. Results : Forty-three articles were included. Twenty one were efficacy tests, thirteen were comparative efficacy tests, eight were toxicity tests, and one was new method development. Eighteen articles were multicenter studies and twenty five were single center studies. Thirty two articles were animal testing, only ten articles were clinical articles. Thirty seven articles presented the composition and quantity of Woohwangchungsim-won, but six did not. Conclusions : The results of Korean articles about Woohwangchungsim-won can not strongly support the effects, significance & necessity of Woohwangchungsim-won. More rigorous studies are required for determination of the effects of Woohwangchungsim-won.
( Do Seon Song ),( U Im Chang ),( Seong Woo Go ),( Jeong Won Jang ),( Si Hyun Bae ),( Seung Kew Yoon ),( Jin Mo Yang ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: We aimed to investigate the association between the change of muscle mass and change of fibrosis and steatosis in NAFLD patients. Methods: We analyzed 2,893 NAFLD subjects who had health check-up more than twice in St. Vincent’s Hospital between November 2009 and December 2017. NAFLD was diagnosed by ultrasound, and appendicular muscle mass (ASM) was assessed by Inbody 720, and Sarcopenia index was calculated as ASM divided by weight (SI%) and ASM divided by body mass index (SI-BMI). Non-invasive markers were used to evaluate the severity of hepatic fibrosis and steatosis; NAFLD fibrosis score (NFS), Fibrosis-4 (Fib-4) score, and Forn’s index for fibrosis, and hepatic steatosis index (HSI) and fatty liver index (FLI) for steatosis. Results: The mean age was 47.3±10.4 years, and 1956 subjects (67.6%) were male. Diabetes, hypertension, metabolic syndrome were more prevalent in sarcopenic subjects (P<0.01), and non-invasive fibrosis and steatosis markers were higher in sarcopenic subjects (P< 0.01). The mean interval between two health check-up was 39.8±21.9 months. There was no significant association between the change of NFS, Fib-4, and Forn’s index and the change of SI% and SI-BMI (all P >0.1). However, the changes of HIS and FLI were significantly associated with the change of SI% and SI-BMI (all P<0.01). Multivariate logistic analysis demonstrated the independent association between the change of skeletal muscle mass and the changes of non-invasive steatosis markers after adjusting for other confounding factors (all P< 0.001). However, the changes of non-invasive fibrosis markers did not show an independent association with the change of appendicular muscle mass after adjusting for other confounders (all P >0.1) Conclusions: The change of muscle mass is strongly associated with the change of hepatic steatosis, but not the change of fibrosis.
Im, Se-Ung,Hong, Ji-Youn,Chae, Gyung-Joon,Jung, Ui-Won,Kim, Chang-Sung,Lee, Yong-Keun,Cho, Kyoo-Sung,Kim, Chong-Kwan,Choi, Seong-Ho Korean Academy of Periodontology 2008 Journal of Periodontal & Implant Science Vol.38 No.2
Purpose: The aim of this study was to evaluate the factors affecting healing patterns of surgically created circumferential gap defects around implants in dogs. Materials and Methods: In four mongrel dogs, all mandibular premolars were extracted. After 8 weeks of healing periods, implants were submerged. According to the surface treatment, turned surface was designated as a group A and rough surface as a group B. In each dog, surgical defects on the left side were made with a customized tapered step drill and on the right with a customized paralleled drill. Groups were also divided according to the width of the coronal gaps: 1.0mm, 1.5mm, or 2.0mm. The dogs were sacrificed following 8 weeks and the specimens were analyzed histologically and histomorphometrically. Results: During the postoperative period, healing was uneventful and implants were well-maintained. As the size of the coronal gap was increased, the amount of bone-to-implant contact was decreased. The bone healing was greater in rough surface implants compared to the turned ones. About the defect morphology, tapered shape showed much bone healing and direct bone to implant contact even in the smooth surface implants. Conclusion: Healing of the circumferential defect around dental implant is influenced by the implant surface, defect width and the morphology of the defect. When using rough surface implants, circumferential gap defects within 2 mm do not need any kinds of regenerative procedures and the healing appeared to be faster in the tapered defect morphology than the paralleled one.
Chang, Won-Du,Im, Chang-Hwan Hindawi Limited 2014 Journal of applied mathematics (JAM) Vol.2014 No.-
<P>Template matching is an approach for signal pattern recognition, often used for biomedical signals including electroencephalogram (EEG). Since EEG is often severely contaminated by various physiological or pathological artifacts, identification and rejection of these artifacts with improved template matching algorithms would enhance the overall quality of EEG signals. In this paper, we propose a novel approach to improve the accuracy of conventional template matching methods by adopting the dynamic positional warping (DPW) technique, developed recently for handwriting pattern analysis. To validate the feasibility and superiority of the proposed method, eye-blink artifacts in the EEG signals were detected, and the results were then compared to those from conventional methods. DPW was found to outperform the conventional methods in terms of artifact detection accuracy, demonstrating the power of DPW in identifying specific one-dimensional data patterns.</P>
Estimation of directional coupling between cortical areas using Near-Infrared Spectroscopy (NIRS)
Im, Chang-Hwan,Jung, Young-Jin,Lee, Seungduk,Koh, Dalkwon,Kim, Do-Won,Kim, Beop-Min The Optical Society 2010 Optics express Vol.18 No.6
<P>This study invesitigated the feasibility of measuring directional coupling between cortical areas with near-infrared spectroscopy (NIRS). Cerebral hemodynamic responses were recorded at the primary somatosensory cortex (S1), secondary somatosensory cortex (S2), and primary motor cortex (M1) regions of the rat barrel cortex during electrical stimulation of rat whiskers. Deoxyhemoglobin concentration changes were calculated from NIRS recordings and the Granger causality based on the multivariate autoregressive (MVAR) model was used to estimate the effective causal connectivity among S1, S2, and M1. The estimated causality patterns of seven rats showed consistent unidirectional coupling between the somatosensory areas and the motor areas (S1 and S2-->M1), which coincided well with our hypothesis because the rats' motor function was completely anesthetized. Our preliminary results suggest that cortico-cortical directional coupling can be successfully investigated with NIRS.</P>