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황경희 이화여자대학교 교육대학원 1995 교과교육연구 Vol.4 No.-
The purpose of this study is to find the qualitative difference of writing perfomance according to topic interest when elementary school children compose experiential writing. To meet this purpose, three questions have been set up as follows: 1. Is there any significant difference in their writing performance when compose experiential writing with high and low interest topics? 2. Is there any significant difference in their writing performance in regard to the variable sex? 3. Is their any significant difference in their writing performance of interest, sex and jointly? The one hundred and eight-seven children(100 boys and 87 girls) in 4 public elementary school third grade in Seoul, chosen for the subject of this study. The subjects were devided into two experimental groups, the one group were written about high interest topics : 'the snowy day’ and 'a school excursion'. The other experimental group were written about low interest topics: 'on the way to school' and 'the rainy day'. The experimental procedure were topic interest test and composing experiential writing. The children's writing were rated by three trained rator including researcher. The rated data were analyzed by General Linear Models(GLM ). The results of the study are as follows : 1. There was significant difference in originality of content, connection of theme and topic, richness of cotent, closeness of theme-topic-title, unity organization, and punctuation of experiential writing in regard to interest level. There was not significant difference in spelling, chronological organization, unusual beginning, and unusual dialogue of experiential writing in regard to interest level. 2. There was significant difference in connection of theme and topic, richness of content, unity in organization, unusual beginning, and unusual dialogue of experiential writing performance in regard to sex. The girl got significant high score in connection of theme and topic, richness of content, unity in organization, unusual beginning, and unusaual dialogue compare with boy. 3. There was significant difference in experiential writing performance in regard to the variable of group and sex, jointly. The boy showed significant high score in spelling when written about high interest topics compare with girl.
손상된 불가사리 추출물 흡입이 포름알데히드 노출에 의한 항염증 작용에 미치는 효과
황경희,장수찬,박종석,Fazli Wahid,김유영 한국생명과학회 2013 생명과학회지 Vol.24 No.4
Formaldehyde (FA) is widely used in industries, and it is an indoor and outdoor pollutant. Exposure to FA may cause inflammation and respiratory oxidative stress. Studies have demonstrated that FA can cause cancer in animal models. During the regeneration process of injured starfish (Asterina pectinifera), several changes have been observed in the expression of cytokines. In particular, higher TGF-β1 expression has been detected in arm cut starfish extract after eight days. The current study was designed to elucidate the in-vitro and the in-vivo pharmacological effects of starfish extract on FA exposure. We investigated the protective effects of intact starfish extract and arm cut starfish extract on an IMR-90 cell line and on mouse lung injury in response to FA exposure. In the presence of FA, inhalation of the arm cut starfish extract was associated with more promising cell proliferation, TNF-α, NF-κB decrement, and Ik-Bα increment. In the experimental group, the pulmonary structure of the arm cut starfish extract-treated group in the presence of FA exposure was similar to the control group, whereas the FA exposure group showed damage to the pulmonary structure. Moreover, the arm cut starfish extracts was more effective than the intact starfish extracts in terms of the expression of TNF-α, NF-κB, Iκ-Bα, and surfactant protein A. The results obtained in this study demonstrate that arm cut starfish extracts are more effective in protecting pulmonary structure and function against FA exposure than intact starfish extracts. 포름알데히드는 주로 산업용으로 사용되는 독성이 강한 물질로서 생체에 노출 시 염증, 산화적 스트레스, 알레르기 반응, 나아가서 암을 유발하게 된다. 불가사리에서 추출되는 saponin은 sulphated sterol glycosides 등으로서 인삼 saponin (ginsenoside)들과 화학적 구조가 비슷하여 항균 및 세포독성을 비롯한 미생물을 괴사시키는 기능을 가지고 있음이 보고되었다. 또한 손상된 불가사리의 조직에는 염증성 사이토카인이 발현되는데 TGF-β의 증가로 손상 받은 부위를 빠르게 치료, 재생하게 된다. 본 실험은 조직손상 후 8일 된 불가사리 추출물과 포름알데히드를 IMR-90에 처리했을 때와 포름알데히드에 노출시킨 ICR 마우스에 불가사리 추출물을 흡입시켰을 때 염증성 폐 손상의 방어 및 치료에 미치는 효과를 알아보았다. 포름알데히드에 노출된 IMR-90에 조직손상 후 8일이 경과한 불가사리 추출물을 처리한 결과, 세포의 유의한 증식을 보였으며 염증 조절에 영향을 주는 TNF-α, NF-κB의 발현억제 및 Ik-Ba의 합성을 촉진시켰다. 포름알데히드에 노출된 ICR 마우스에 조직손상 후 8일이 경과한 불가사리 추출물을 처리한 군에서 체중의 증가, 항산화 효소의 증가, 지질과산화 작용의 감소, surfactant protein A의 증가, TNF-α 및 NF-κB의 발현억제, Ik-Ba 발현의 증가와 조직재생에 우수한 효과를 보였다. 이러한 결과는 포름알데히드로 인한 세포 및 폐 손상을 불가사리 추출물의 항염증 작용을 통하여 억제하거나 완화시킴을 확인할 수 있다.
초기이유시 식이의 형태가 성장한 쥐의 혈청콜레스테롤 수준에 미치는 영향
황경희,한인규 ( K . H . Hwang,In . K . Han ) 한국축산학회 1985 한국축산학회지 Vol.27 No.7
The effects of preweaning diet experience on the metabolic response of adult male rats were examined. Rats were preweaned on day 18 and were fed a high fat (HF) or a high carbohydrate (HC) diet. After age 3C1 days, each of two preweaned groups (PW) and a normal weaned group (NW) (on day 30) was fed a high fat diet (HF) or a control diet containing 2% cholesterol until 72 days of age. Animal was killed when aged 30 or 72 days and level of serum cholesterol was determined. HF group at 30 days of age had significantly higher serum cholesterol level and had more weight gain, liver weight liver total lipid and liver cholesterol than NW group or HC group. At 72 days of age, serum cholesterol level in HC group (135.61 ㎎/㎗) was double as that of NW group (72.71 ㎎/㎗), and HC group had more weight gain and epididymal fat pad than NW group. Feeding control diet during 6 week postweaning resulted in higher blood cholesterol level than HF diet feeding, but there was no difference in blood cholesterol level between H~C and NW group by feeding a control diet or a HF diet which contained 2% cholesterol. Present results indicate that metabolic systems of blood cholesterol in adult rat are affected by preweaning period and diet.
황경희,이규완,김인선,홍성봉 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.3
The ultrastructural study of endometrium in healthy young women in reproductive age is described days 5, 9, 13, 16-17, 22-23, 24-25 and 27-28 of the menstrual cycle. The results obtained are as follows; 1. The endometrial glandular cell showed relatively well-defined patterns; reparative proliferative on day 5, proliferative on day 9 and 13, early secretory on day 16-17, secretory on day 22-23, and regressive after day 24-25. 2. There is a characteristic triad of events occurring around the time of ovulation; the accumulation of glycogen in a subnuclear position, the formation of a canalicular nucleolar channel system and the development of a giant mitochondria-endoplasmic reticulum unit. 3. The endometrial stromal cells were immature on day 5 and underwent differentiation toward a fibroblasts from day 9 to 22-23. After day 24-25, the stromal cell showed maturation to predecidual cells. 4. The stromal granulocytes were found on the endometrium of day 24-25 and they demonstrated a characteristic membrane-bound secretory granules in their cytoplasm.
황경희 21세기영어영문학회 2004 영어영문학21 Vol.17 No.1
Jean Rhys' fourth novel published in 1939, Good Morning Midnight, is about Sasha, a middle-aged woman returning to Paris for a short holiday. Jean Rhys represents a crisis within the heroine, Sasha, who is on the other side of the privileged classes and the language they speak. Rhys, a West Indies Creole living as an outsider, became acutely sensitive to the exploitation of women and Creole women. In her writing, the marginalized and silenced female protagonists end up in a seemingly miserable situation. However, the miserable reality experienced by them is not all that her novels are about. Her heroines address their anger at the distressing situation and their wish to find a way out. In Good Morning Midnight, Sasha, who has been considered “marginal” or “the other” in the society where she lives, is fully aware of her victimization and tries not to lose her existence. This article aims to explore how Sasha resists the typical images imposed on her and seeks to escape from the darkness. She seems to embody otherness in her own name and nationality and is confined in a prison from which she cannot be freed. She recognizes that her imprisonment has reduced her to being a victim and an "other". However, she is not a blank surface; instead, there is always within her the repressed subtext in which she articulates her insightful awareness of her life and seeks escapes from the impositions. Finally, Sasha finds an exit out of her dire situation by accepting and embracing “the other” within herself with no denial of its otherness.