아토피 피부염 환자의 생활사건 스트레스와 대처방식

한덕현,최한규,기백석,남범우,서성준,Han, Duck-Hyun,Choi, Han-Gyu,Kee, Baik-Seok,Nam, Bum-Woo,Seo, Seong-Jun 한국정신신체의학회 1999 정신신체의학 Vol.7 No.2

Background : Various type of psychological and stressful events in life have been reported to have much effect in the onset, progress and exacerbation of psychosomatic disorders such as hypertension, bronchial asthma, peptic ulcer, tension headache, alopecia areata, and atopic dermatitis. However, the nature of the association between stress and psychosomatic disorders remains unclear. Objective : The purpose of this study is to determine the relation of stress and the progress of dermatologic disorder. Method : We examined 30 patients with atopic dermatitis and 30 control subjects with tinea pedis and onychomycosis who visited to Dept. of Dermatology, Chung-Ang University Hospital. To evaluate the stress, we used 'Scale of Life Events' and 'Multidemensional Coping Scale'. Result : 1) The score of life events stress in atopic dermatitis group was significantly higher than that of control group. 2) In the result of coping strategies, the atopic dermatitis group was significantly higher than control group at the active forgetting, positive comparison, and emotional pacification, while in control group religious seeking and accomodation tended to be higher with no statistical significance. Conclusion : These findings suggest that psychosocial stress may play a role in life pattern of atopic dermatitis. But further studies are needed to clarity the exact relationship between stress and psychosomatic disorder. 연구목적 : 본 연구에서는 사회적, 심리적 관점에서 아토피 피부염에서 보이는 스트레스의 양을 측정 하고 스트레스에 대한 대처 방식의 특정을 알아보고자 하였다. 방법 : 1997년 9월부터 1998년 5월까지 중앙대학교 의과대학 부속병원 피부과에 내원한 20세 이상의 아토피 피부염 환자를 분석 대상으로 생활사건 척도(Scale of Life Event)와 다차원적척도(Multimensional Coping Scale)를 이용하여 스트레스 정도와 대처방식의 차이를 알아보고자 하였다. 결과 : 생활 사건에 대한 스트레스의 양은 아토피 피부염 환자군이 $386.52{\pm}257.93$이었고, 대조군은 $255.98{\pm}161.93$으로 통계적으로 유의한 차이를 보였고 대처 방식에 있어서는 아토피 피부염 환자군에서 적극적 망각 척도, 정서적 진정 척도, 긍정적 비교 척도에서 각각 $7.30{\pm}3.56$(t=2.55. df=53, p=0.013), $8.0{\pm}2.05$(t=2.42. df=58, p=0.019), $6.00{\pm}4.97$(t=2.48, df=58, p=0.16)으로 대조군에 비해 통계적으로 유의하게 높았다. 결론 : 스트레스는 아토피 피부염의 발생 및 악화에 영향을 미칠 것으로 추정되며, 적극적 망각과 같은 정서중심적, 비효과적 대처방식을 문제 중심적 대처로 변환시키고 자신보다 못한 상태에 있는 타인을 비교함 자신의 상태를 유지하려하는 인지적 측면과 스트레스 상황에서 발생한 정서적 혼란을 가라앉히려는 정서적 측면에 대해 지지적 치료가 이루어지면 아토피 피부염을 비롯한 정신 신체 질환의 치료에 도움이 될 것으로 생각된다.

GABA_(A)α6 유전자 다형성에 따른 알코올 금단 증상의 발현 차이

한덕현,최정은,이병용,김영훈,김혜원,이혜경 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Introduction : The gamma-aminobutyric acid type A (GABA_(A)) receptor is an important pharmacological target of alcohol.The phamacological characteristics of the receptor are largely determined by its subunit composition, Compared with all othera subtypes, the α 6- containing receptors are more sensitive to GABA and less sensitive to benzodiazepines. The purpose of thisstudy was to address a role for GABA_(A) α 6 receptor subunit gene in the development of alcohol dependence. The differentialmanifestation of alcohol withdrawal symptoms related to GABA_(A) α 6 polymorphism in patients treating with benzodiazepineswas also examined.Methods : Eighty-seven inpatients with alcohol dependence, and sixty healthy controls were evaluated using CIWA-Ar scale.Each patient was genotyped for GABA_(A) α 6 subunit. Association between GABA_(A) α 6 polymorphism and severity of Withd-rawal symptom were determined.Results : No significant difference was found in GABA_(A) α 6 receptor genetic type and allelic distribution between thealcohol dependent and control subject. Tremor was more severe in CC than TT type. TT type had higher degree of anxiety,agitation and headache than CC type. The GABA_(A) α 6 C allele increased the average score of tremor significantly, and T alleleincreased that of agitation.Conclusion : The results suggested that GABA_(A) α 6 genetic polymorphism was not associated with alcohol dependenceand with severity of alcohol withdrawal symptoms. But in benzodiazepine treated patients, GABA_(A) α 6 polymorphism andallelic type show the difference in severity of each withdrawal symptom. These differences of sevehty are partly responsiblefor the unique pharmacological properties associated with the GABA_(A) α 6 subunit.

인터넷 중독의 약물 치료

한덕현 대한소아청소년정신의학회 2011 대한소아청소년정신의학회 학술대회논문집 Vol.2011 No.8

한국 남성들의 건강 및 성기능에 대한 인식 및 행동양식의 조사: 정성적인 분석

한덕현,김지혜,이성원,이형석 대한남성과학회 2005 The World Journal of Men's Health Vol.23 No.2

표면 처리를 통한 친환경 방오 기술 및 실해역 평가 연구

한덕현,고혁준,정항철 한국표면공학회 2022 한국표면공학회지 Vol.55 No.6

Antifouling paints that inhibit the attachment and contamination of marine organisms mainly use TBT compounds, but because of their toxic components, they cause ecosystem disturbance and environmental destruction problems, so It is necessary to research eco-friendly antifouling paints that are easy to maintain and effective antifouling technologies. In this study, physical surface treatment of silane coating and chemical antifouling technology were applied to the metal surface to secure the stability of the surface of the marine structure and inhibit the attachment and growth of marine organisms. Adhesion of marine organisms was evaluated according to the coating conditions through surface evaluation of the charged material for 15 months in the waters of the west coast of Korea. In accordance with ASTM D6990-05, antifouling properties fouling rates (FR) and physical degradation rates(PDR) were evaluated through visual inspection of the evaluation specimens. As a result of evaluating the antifouling performance of the coated surface, it was confirmed that the antifouling performance was maintained at the 50% level even after 15 months in the sample subjected to physical processing and silane coating.

성인 주의력결핍 과잉행동장애 환자의 주의력 테스트, 인지 기능, 임상증상과의 관계

한덕현 대한소아청소년정신의학회 2019 대한소아청소년정신의학회 학술대회논문집 Vol.2019 No.5

물리적/화학적 친환경 표면 처리 방오 기술의 실해역 적용 평가

한덕현,고혁준,정항철 한국표면공학회 2022 한국표면공학회 학술발표회 초록집 Vol.2022 No.11

Korean Version of Inventory of Complicated Grief Scale: Psychometric Properties in Korean Adolescents

한덕현,이정재,문덕수,차명진,김민아,민선영,양지훈,이은정,유서구,정은선 대한의학회 2016 Journal of Korean medical science Vol.31 No.1

We aimed to validate the Inventory of Complicated Grief (ICG)-Korean version among 1,138 Korean adolescents, representing a response rate of 57% of 1,997 students. Participants completed a set of questionnaires including demographic variables (age, sex, years of education, experience of grief), the ICG, the Children’s Depression Inventory (CDI) and the Lifetime Incidence of Traumatic Events-Child (LITE-C). Exploratory factor analysis was performed to determine whether the ICG items indicated complicated grief in Korean adolescents. The internal consistency of the ICG-Korean version was Cronbach’s α = 0.87. The test-retest reliability for a randomly selected sample of 314 participants in 2 weeks was r = 0.75 (P < 0.001). Concurrent validity was assessed using a correlation between the ICG total scores and the CDI total scores (r = 0.75, P < 0.001). The criterion-related validity based on the comparison of ICG total scores between adolescents without complicated grief (1.2 ± 3.7) and adolescent with complicated grief (3.2 ± 6.6) groups was relatively high (t = 5.71, P < 0.001). The data acquired from the 1,138 students was acceptable for a factor analysis (Kaiser-Meyer-Olkin Measure of Sampling Adequacy = 0.911; Bartlett’s Test of Sphericity, χ2 = 13,144.7, P < 0.001). After omission of 3 items, the value of Cronbach’s α increased from 0.87 for the 19-item ICG-Korean version to 0.93 for the 16- item ICG-Korean version. These results suggest that the ICG is a useful tool in assessing for complicated grief in Korean adolescents. However, the 16-item version of the ICG appeared to be more valid compared to the 19-item version of the ICG. We suggest that the 16-item version of the ICG be used to screen for complicated grief in Korean adolescents.

Stone-breaking and retrieval strategy during retrograde intrarenal surgery

한덕현,전승현 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.4

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The Korean Version of the Pediatric Symptom Checklist: Psychometric Properties in Korean School-aged Children

한덕현,우정민,정재훈,황선영,정운선 대한의학회 2015 Journal of Korean medical science Vol.30 No.8

Psychosocial problems increase the risk for mental health problems and increase the need for health care services in children and adolescents. Primary care practice is a valuable avenue for identifying the need for more specialized mental health care. We hypothesized that Korean version of the pediatric symptom checklist (PSC) would be a useful tool for early detection of psychosocial problems in children and adolescents in Korea and we aimed to suggest cut-off scores for detecting meaningful psychosocial problems. A total of 397 children with their parents and 97 child patients with their parents were asked to complete the PSC Korean version and the child behavior checklist (CBCL). The internal reliability and test-retest reliability of the PSC as well as the cut-off score of the PSC was determined via receiver operating characteristic analysis of the CBCL score, clinical group scores and non-clinical group scores. The internal consistency of the PSC-Korean version was excellent (Cronbach’s alpha = 0.95). The test-retest reliability was r = 0.73 (P < 0.001). Using clinical CBCL scores (total score, externalizing score, internalizing score, respectively ≥ 60) and presence of clinical diagnosis, the recommended cut-off score of the PSC was 14. Using 494 Korean children aged 7-12 yr, the current study assessed the reliability and validity of a Korean version of the PSC and suggested a cut-off for recommending further clinical assessment. The present results suggest that the Korean version of the PSC has good internal consistency and validity using the standard of CBCL scores.