http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
인간행동 시뮬레이션을 통한 노인주거 피난안전성 검증에 관한 연구
조승우,김경배 대한건축학회 2019 대한건축학회논문집 Vol.35 No.9
Recently as the rapid increasing of the elderly, silver housing has grown up. Though much fire evacuation and safety law, fire accident ismost dangerous problem in our society. So this study is the purpose to analyze evacuation safety in urban silver housing of floor planningby corridor types using human behavior simulation. The methodology of this study is ‘Literature Review’ and ‘Simulation’. This study hasbeen carried out on silver housing’s definition, types, fire safety theory and relation law. To proof evacuation safety, this study measuredescaping time, longest distance, and bottleneck counting using human behavior simulation. This study use game engine simulation program toanalyze 6 corridor types experimental model. As the result of simulation, this study compare between ASET and simulation result. The resultcome down to 3 part. First, double loaded corridor type is the most dangerous on urban silver housing. Second, Safe shelter’s location andnumber cause increasing of escaping time. Lastly escaping time is influenced by behavior of agent, bottle neck strike frequency. 피난 및 화재에 관한 많은 법률이 제정되어있음에도, 노인주거의 화재 사고는 증가하고 있다. 본 연구의 목적은 도심형 노인주거의 피난안전성을 검증하기 위해 복도유형 별 건축계획을 도출하고, 시뮬레이션 분석을 통해 피난에 가장 합리적인 건축계획을 제시하는 것이다. 노인주거의 피난안전을 검증하기 위해 사용한 본 연구의 연구방법론은 문헌연구와 인간행동 시뮬레이션이다. 문헌연구를 통해 노인주거의 정의, 유형을 고찰하고, 일본 건축기준법을 참고하여 피난허용시간을 도출하였다. 또한, 시뮬레이션을 통하여 가상공간 내 유형화된 노인주거 평면계획을 실험하여 피난시간을 도출하였다. 본 연구에서는 피난안전에 가장 합리적인 복도유형을 도출하기 위하여 시뮬레이션 분석을 통해 산출된 피난시간과 문헌연구를 통해 도출된 피난허용시간을 비교 및 검증하였다. 도출된 실험 결과는 다음과 같다. 중복도 유형이 피난허용시간을 초과한 유형으로 나타났으며, 재실자 및 관리자의 행동과 병목현상, 피난처의 수와 편중은 피난시간에 영향을 미치는 것으로 분석되었다.
Biomaterials for the control of stem cell differentiation and cellular reprogramming
조승우 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0
Stem cell therapeutics have shown great potential for the treatment of incurable diseases, but their therapeutic efficacy needs to be improved by enhancing specific lineage differentiation for efficient tissue regeneration. Direct reprogramming has been highlighted for the generation of tissue-specific cell types, but low efficiency still remains a major challenge. In this presentation, several materials and devices will be introduced to promote neuronal differentiation of stem cells and direct conversion of skin fibroblasts to neuronal lineage cells. In the first part, microfluidic devices and nanoscale patterned substrates for the reconstitution of neural stem cell microenvironments are reported to promote functional neuronal differentiation. In the second part, micro-devices generating external stimulation and brain-specific microenvironment are reported for significantly improving the efficiency of polymer nanoparticle-mediated direct neural conversion.
A Systematic Proteome Study of Seed Storage Proteins from Two Soybean Genotypes
조승우,우선희,Soo-Jeong Kwon,Swapan Kumar Roy,Hong Sig Kim,이철원 한국작물학회 2014 Korean journal of crop science Vol.59 No.3
Soybean seed is a good source of plant proteinin human consumables such as baby formula and proteinconcentrate. The seeds contain an abundance of storageproteins, namely β-conglycin and glycinin that account for ~70-80% of the total seed protein content. Proteome profilinghas been proved to be an efficient way that can help usto investigate the seed storage proteins. In the present study,the seeds were removed from the pods and the cotylendonarytissues were separated from the testa for proteome analysisin order to investigate the seed storage proteins. A systematicproteome profiling was conducted through one-dimensionalgel electrophoresis followed by MALDI-TOF-TOF massspectrometry in the seeds (cotyledonary tissue) of soybeangenotypes. Two dimensional gels stained with CBB, a totalof 10 proteins were identified and analyzed using MASCOTsearch engine according to the similarity of sequences withpreviously characterized proteins along with the UniProtdatabase. A total of ten proteins such as glycinin Gy4 precursor,glycinin G3 precursor, glycinin G1 precursor, glycinin chainA2B1a precursor, glycinin chain A2B1a precursor wereidentified in our investigation. However, the glycinin subunitmay be considered to play important roles in soybean breedingand biochemical characterization. In addition, the improvedtechnique will be useful to dissect the genetic control ofglycinin expression in soybean