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조성필,이재훈,김철환,Cho, Sung-Pil,Lee, Jae-Hoon,Kim, Chul-Hwan 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.2
Mandibular fractures have higher incidence rate compared to facial bone fractures because of relatively prominent form. Specially, mandibular angle fractures were known as common fracture site because of morphological anatomic structure. The mandibular third molar appears to be the most frequent impacted tooth. The mandibular third molar have influence on mandibular angle fractures according to it's eruption state. Also, the mandibular angle fracture including the third molar may influence on post operative infection whether the third molar is in impacted or extracted state when reduction of fracture site is operated. The presence or absence and degree of impaction of the mandibular third molar were assessed for each patient and were related to the occurrence of the mandibular angle fracture. The extraction or non extraction of the mandibular third molar were related to the occurrence of the post operative infection in the reduction of mandibular angle fractures. In the presence of mandibular third molar, the possibility of mandibular angle fractures were relatively common. When viewing the mandibular third molar at occlusal plane, the possibility of mandibular angle fractures were high in the class C group. The possibility of mandibular angle fractures were high in the mesial angulation and partial impaction. There was a statistically significant difference(P<0.05). In complete erupted mandibular third molar, the possibility of post operative infection occurs quite often, but there was no statistical significant difference(P>0.05). In the extracted or non extracted of mandibular third molar, the post operative infection showed no statistical significant difference(P>0.05). With the results mentioned above, mandibular third molar was significantly more susceptible to mandibular angle fracture. In the reduction of mandibular angle fracture, it was recommended that mandibular third molar should be extracted especially in case of pericoronitis, periodontitis and other infections.
T - cell Epitope을 운반할 수 있는 재조합소아마비바이러스벡터의 제조 및 특성연구
조성필,이범용,정수일,민미경 대한바이러스학회 1998 Journal of Bacteriology and Virology Vol.28 No.2
Recombinant polioviruses have been developed by many research groups for use as vaccine vector because poliovirus induces mucosal immunity as well as humoral immunity through oral uptake. We assessed the potential use of poliovirus as a T-cell epitope carrier. Recombinant poliovirus V129 SL was constructed to have a substituted T-helper epitope from the core protein of Hepatitis B virus at neutralization antigenic site 1 on its VP1 capsid protein. The recombinant virus replicated less efficiently than type 1 poliovirus Mahoney strain. The V129 5L formed a little smaller plaques than the Mahoney strain and showed some 1.25 log unit lower titer at the peak in the one-step growth kinetics though it had similar growth profile to that of the Mahoney strain. Since V129 SL recombinant virus was genetically stable even after 24 successive passages in HeLa cells, the antigenic site 1 on VP1 capsid protein was confirmed for its ability of carrying T cell epitope. The genetic stability of V129 SL also indicated that recombinant poliovirus can be successfully utilized for the development of the multivalent vaccines.
단일 채널 뇌전도를 이용한 호흡성 수면 장애 환자의 각성 검출
조성필,최호선,이경중 대한전기학회 2006 전기학회논문지 D Vol.55 No.5(D)
- Frequent arousals during sleep degrade the quality of sleep and result in sleep fragmentation. Visual inspection of physiological signals to detect the arousal events is cumbersome and time-consuming work. The purpose of this study is to develop an automatic algorithm to detect the arousal events. The proposed method is based on time-frequency analysis and the support vector machine classifier using single channel electroencephalogram (EEG). To extract features, first we computed 6 indices to find out the informations of a subject's sleep states. Next powers of each of 4 frequency bands were computed using spectrogram of arousal region. And finally we computed variations of power of EEG frequency to detect arousals. The performance has been assessed using polysomnographic (PSG) recordings of twenty patients with sleep apnea, snoring and excessive daytime sleepiness (EDS). We could obtain sensitivity of 79.65%, specificity of 89.52% for the data sets. We have shown that proposed method was effective for detecting the arousal events.
IT 거버넌스 통제에 대한 조직원의 심리적 반발요인에 대한 연구
조성필,임채영,이재환,안종창 한국지능정보시스템학회 2012 한국지능정보시스템학회 학술대회논문집 Vol.2012 No.12
본 연구는 다양한 형태의 조직들에서 IT 거버넌스와 관련된 통제에 대해 조직원들의 모바일 기기를 중심으로 한 개인 기기 사용 확산에 따른 반발 심리의 분석에 초점을 둔다. 이를 위해 IT 거버넌스 통제와 관련된 선행 연구, 조직원의 반발 심리에 대한 척도 및 기대이론을 바탕으로 설문지를 구성하였다. Hong의 심리적 반발 척도, 기대이론의 보상 정도, 회사의 직급이나 조직 규모에 따라 조직원들의 IT 통제에 대한 반발요인의 통계적 유의성 정도를 분석할 수 있었다. 이를 통해 IT 거버넌스를 통한 경영목표달성을 위한 통제와 조직원 반발요인에 대한 정밀한 분석을 통해 실무적, 이론적인 공헌을 한다.
조성필,조용철,안상태,오영환 대한성형외과학회 2002 Archives of Plastic Surgery Vol.29 No.5
Oriental hump nose is characterized by mild degree of the hump, broad dorsum, low nasal height and drooping tip. Therefore, conservative humpectomy followed by either tip-plasty or augmentation rhinoplasty yields more satisfactory results than classical Joseph's nasal hump reduction. However, the degree of the hump as well as the length of the nose can be affected by the height of the nasal root. That is, if the nasal root is too low, the hump nose may stand out and the nose will seem longer than the actual measurements. We think that it is important to consider the height of the nasal root in the course of the nasal hump reduction. During the last 2 year periods, we have classified twenty eight patients with hump nose into three groups, low(group A: 7 patients), moderate(group B: six patients) and high(group C: fifteen patients), based on the nasal root height. Each group went through different operative procedures according to their nasal root height and favorable results were obtained.