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호지킨병 초기에 주증상으로 발현된 거대세포바이러스 유발 위궤양
황의태 ( Eui Tae Hwang ),이준영 ( Jun Young Lee ),정진수 ( Jin Soo Chung ),이재훈 ( Jae Hoon Lee ),최창수 ( Chang Soo Choi ),김태현 ( Tae Hyeon Kim ),최석채 ( Suck Chei Choi ) 대한소화기학회 2009 대한소화기학회지 Vol.54 No.2
Cytomegalovirus (CMV) is an important cause of opportunistic infection in immunocompromised patients. CMV infection occurs as a result of the cell-mediated immunity change in lymphoma patients. Although CMV can cause ulceration anywhere in the gastrointestinal (GI) tract in immunocompromised patients, only a few case reports about CMV GI infection in malignant lymphoma have been documented in literature. Furthermore, it was rare that CMV gastric ulcer with massive bleeding presented as an initial manifestation in a patient who has been not diagnosed lymphoma. We report a case of CMV induced gastric ulcer as an initial manifestation in patient with Hodgkin`s disease. (Korean J Gastroenterol 2009;54:117-122)
새로운 PROS1 유전자 변이에 따른 S 단백 결핍증에 의한 간문맥-비장정맥-장간막정맥 혈전증
황의태 ( Eui Tae Hwang ),강원식 ( Won Sik Kang ),박진우 ( Jin Woo Park ),이지현 ( Ji Hyun Lee ),한현정 ( Hyun Jeong Han ),신상용 ( Sang Yong Shin ),김희진 ( Hee Jin Kim ),최자성 ( Ja Sung Choi ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.2
Protein S (PS), a vitamin K-dependent glycoprotein, performs an important role in the anticoagulation cascade as a cofactor of protein C. Because of the presence of a pseudogene and two different forms of PS in the plasma, protein S deficiency (PSD) is one of the most difficult thrombophilias to study and a rare blood disorder associated with an increased risk of thrombosis. We describe a unusual case of previously healthy 37-year-old man diagnosed with portal splenic mesenteric vein thrombosis secondary to PSD. The patient was admitted to the hospital due to continuous nonspecific abdominal pain and nausea. Abdominal computed tomography revealed acute venous thrombosis from inferior mesenteric vein to left portal vein via splenic vein, and laboratory test revealed decreased PS antigen level and PS functional activity. Conventional polymerase chain reaction and direct DNA sequencing analysis of the PROS1 gene demonstrated duplication of the 166th base in exon 2 resulting in frame-shift mutation (p.Arg56Lysfs*10) which is the first description of the new PROS1 gene mutation to our knowledge. Results from other studies suggest that the inherited PSD due to a PROS1 gene mutation may cause venous thrombosis in a healthy young man without any known predisposing factor. (Korean J Gastroenterol 2014,64:110 114)
김태형(Tae Hyoung Kim),이성주(Seang Ju Lee),김의태(Eui Tae kim),김창수(Chang Su Kim),황장순(Jang Sun Hwang),유상재(Sang Jae Yoo),김동성(Dong Seang Kim) 대한CT영상기술학회 2015 대한CT영상기술학회지 Vol.17 No.2
목적 : CT검사 시 발생할 수 있는 피검사자를 제외한 민원의 표면선량 및 흡수선량을 측정하여 수치화하여 불필요한 피폭을 최소화 할 수 있는 방법을 찾고자 하였다. 대상 및 방법 : 본원의 Somatom Sensation 16 MDCT장비를 사용하여 water phantom을 scan 하였고 거리와 보호 장비 착용유무에 변화를 두어 Atom팬텀의 흡수선량과 표면선량을 측정하였다. 결과 : 표면선량과 흡수선량 모두 방사선 보호 장비의 착용 및 거리에 따라 흡수율이 크게 감소됨을 알 수 있었다. 결론 : 피검사자외의 인원이 불가피하게 위치하여야 경우 gantry와의 거리를 2M이상으로 유지한 상태에서 기준에 맞는 방사선 보호 장구를 착용하였을 시 흡수선량이 큰 폭으로 감소함을 확인 할 수 있었다. 불가피한 의료 방사선의 피폭을 최소화 하기 위해 방사선 보호 장구의 착용은 필수적인 요소이며 거리에 따른 감소도 더욱 신경 써서 지켜야 할 필요가 있다. Purpose : To minimize an unnecessary radiation dose which might affects to medical staffs or patient guardians who stay aside a patient in a CT room. This study was evaluated by a metric of the effective dose and surface dose. Materials and Methods : This study was performed with a water phantom and anthropomorphic body phantom (Atom) using 16- channel MDCT (Somatom, Sensation, Siemens). The metrics were designed into two categories which one is a scan with protection equipment (Lead Apron) and the other is without the protection. Also, radiation doses were measured at various distances from X-ray exposure spot. Results: The absorption rate of the surface dose and absorbed dose were highly reduced with the protection equipment and over 1 meter from X-ray source spot. Also, the effective dose was reduced significantly. Conclusion : It is clear that the both absorbed and surface dose were reduced by the proper protection equipments (Lead Apron and Thyroid guard) and 2 meters distance from X-ray exposure spot. It is an essential factor that we have to provide the proper protection to medical staffs and the patient guidance to minimize unnecessary radiation dose.
마이크로파 조사가 산화그래핀의 화학적 박리에 미치는 효과
이재희,황기완,정영훈,김의태,Lee, Jae-Hee,Hwang, Ki-Wan,Jeong, Young-Hoon,Kim, Eui-Tae 한국재료학회 2013 한국재료학회지 Vol.23 No.12
Graphene oxide has been synthesized by microwave-assisted exfoliation of graphite oxide prepared by modified Hummers method. Graphite was oxidized in a solution of $H_2O_2$ and $KMnO_4$ at $65{\sim}80^{\circ}C$, followed by 10 % $H_2O_2$ solution treatment at $80{\sim}90^{\circ}C$. The graphite oxide was exfoliated under microwave irradiation of 1 kW and was reduced to graphene effectively by hydrazine hydrate ($H_4N_2{\cdot}H_2O$) treatment. The exfoliation of graphene oxide was significantly affected by the microwave irradiation on (heating)/off (cooling) period. An on/off period of 10 s/20 s resulted in much more effective exfoliation than that of 5 s/10 s with the same total treatment time of 10 min. This can be explained by the higher exfoliation temperature of 10 s/20 s. Repetition of the graphite oxidation and exfoliation processes also enhanced the exfoliation of graphene oxide. The thickness of the final graphene products was estimated to be several layers. The D band peaks of the Raman spectra of the final graphene products were quite low, suggesting a high crystal quality.
이재훈 ( Jae Hoon Lee ),황의태 ( Eui Tae Hwang ),김기훈 ( Ki Hoon Kim ),조향정 ( Hyang Jeong Jo ),김태현 ( Tae Hyeon Kim ),최석채 ( Suck Chei Choi ),최창수 ( Chang Soo Choi ) 대한소화기학회 2009 대한소화기학회지 Vol.53 No.4
Actinomycosis is a chronic suppurative and granulomatous disease, characterized by the formation of abscess, draining sinuses, abundant granulation, and dense fibrous tissue. Actinomycosis of the gallbladder is extremely rare. We report a case of an 56-years old man who abruptly presented with right upper quadrant abdominal pain. Abdominal CT showed that the gallbladder had 2 cm sized stone and an edematous thick wall. Our preoperative diagnosis was acute calculous cholecystitis. After the management of acute cholecystitis, laparoscopic cholecystectomy was performed but converted to open surgery due to severe adhesion to liver and greater omentum. Partial cholecystectomy was performed. Histologic section of the gallbladder showed sulfur granule with gram-positive branching bacilli compatible with actinomyces. After cholecystectomy, the patient received intravenous penicillin G for 2 weeks, followed by oral penicillin for 3 months. (Korean J Gastroenterol 2009;53:261-264)