출생전에 시행한 염색체검사의 분석에 관한 임상적 고찰

이순미 ( Soon Mi Lee ),이순곤 ( Soon Gone Lee ),최규연 ( Kyu Yeon Choi ),이정재 ( Jeong Jae Lee ),이임순 ( Im Soon Lee ),이권해 ( Kwon Hae Lee ) 대한주산의학회 1996 Perinatology Vol.7 No.1

벼의 생육과 수량에 미치는 피와 물달개비의 경합효과

이순계(Sun-Gye Lee),임일빈(Il-Bin Im),김도순(Do-Soon Kim),변종영(Jong-Yeong Pyon) 韓國雜草學會 2006 Weed&Turfgrass Science Vol.26 No.3

시진핑 출범 이후 중국 방송정책의 특징과 변화

이순임(Soon-Im Lee),강병환(Byung-Hwan Kang) 부산울산경남언론학회 2015 지역과 커뮤니케이션 Vol.19 No.4

2012년에 취임한 중국의 시진핑 국가주석은 집정이념을 ‘중국꿈(中国梦)’으로 설정하고, 이를 달성하기 위해 ‘4개전면(4個全面)’을 국가정책으로 제시했다. 시진핑 주석이 제시한 4개전면의 구체적인 내용은, 중국이 2021년까지 국가의 자원을 총체적으로 집약시켜서 전면적인 소강사회 건설(全面建成小康社会: 중산층 사회 건설)을 완성하고, 2049년까지 현대화된 사회주의를 완성하여 ‘중국꿈’을 실현하겠다는 계획이다. 상명하복의 정치 · 문화적 전통을 유지하고 있는 중국의 정치체제는 시진핑 주석이 제시한 ‘4개전면’의 목표를 달성하기 위한 홍보수단으로서 방송을 정책적으로 활용하고 있다. 시진핑 주석은 그의 집정이념을 달성하기 위한 통치수단으로, 당의 시각으로 언론을 통제한다는 3대 정치가판(政治家瓣)을 언론정책을 제시하였다. 3대 정치가판이란 정치가판보(政治家辦報, 신문)와 정치가판간(政治家辦看, 잡지), 정치가판대(政治家辦台, 방송)를 말하는데, 이것은 과거 마오쩌둥(毛澤東) 시절에 활용하던 언론정책이다. 시진핑 주석은 중국의 모든 신문과 잡지, 방송분야를 당의 시각으로 견지하고, 이를 통해서 사상정신과 군중노선 및 사회여론을 주도하여 전파 · 인도하며 교육실천운동으로 결합해야 한다고 방송정책의 내용과 방향을 제시했다. 중국의 시진핑 정부가 제시한 방송정책의 특징과 변화를 살펴보면, 이전보다 강력한 언론 통제를 통해서 기존 사회주의 체제의 문화체계를 그대로 유지하면서도 한편으로는 우수한 외래문화를 점차적으로 받아들이려는 노력의 일환으로 보여진다. 즉 중국의 전통문화를 보호하면서 타문화로부터의 침투와 범람을 막기 위한 전면적인 ‘문화 안전’을 구축하기 위한 구체적인 조치라고 하겠다. 이러한 선상에서 현재 중국에서는 포맷 구입을 통해 중국식으로 제작한 한국의 예능프로그램이 크게 인기를 끌면서 새로운 한류시대를 맞고 있다. 중국정부의 강력한 견제와 한류의 시장성 간의 미묘한 균형이 또 다른 형태의 한류로 나타나고 있는 것이다. ‘정열문냉(政熱文冷)’ 즉 정치적으로는 가까운 관계를 유지하면서도 문화적으로는 한류를 견제하려는 중국의 문화정책의 틈을 비집고, 한국의 방송콘텐츠는 중국의 문화시장에서 상품성과 경쟁력을 갖춘 새로운 형태의 한류로 출현하여 다시 인기를 끌고 있다. 이것은 이제 세계가 글로벌화되어 있음을 반영하는 것이며 동시에 문화를 정책적으로 제한하려는 중국의 문화정책의 한계를 보여준다고 하겠다. 중국의 문화정책의 범위 내에서 예능이라는 새로운 차원의 방송콘텐츠로 제작된 한국의 예능 프로그램은 중국의 문화시장을 무대로 또 다시 새로운 한류 바람을 일으키고 있다. New era of Xizinping has begun with various policies, for instance, the four overall(4個全面), and China dream(中國夢), which shapes and characterizes the future of China. Xi’s main idea in politics accelerated its socialist ideology sternly. Such ideological principal gave a way of direction in cultural policies through media policies. Cultural policies by Xi regime showed more conservative trend in the name of protecting Chinese traditional culture. As a ideological tool of education to the people, Xi’s policies in culture aimed at giving a political influence to Chinese through political hardware with cultural software, stressing renaissance of Chinese traditional culture. With a purpose of vitalizing cultural competitiveness to the world in cultural industry, China launched duplicate policies, has opened its broadcasting market to Chinese-speaking regions, Hong, Taiwan and restricted to the regions of western societies including Korea. Hallu was a undeniable phenomenon that enjoyed its heyday triggered by dramas in China. Big success of Korean drama in China created a sensation to the Chinese, stimulated Chinese government to be able to step up its level of making dramas through policies. The heyday of Hallu in China suffered a bitter blow to protect Chines culture from Korean culture. Various restrictions, especially to Korean dramas seemed to be success of calming Hallu fever down temporarily. The development of internet made it possible to reappear Hallu in China, which is totally different trend and phenomenon from former way of enjoying Korean dramas. “lover from star” triggered the newly formed Hallu fever in Chines society by using internet device. So called second Hallu also was surged by drama resulted in Chines tourism and gigantic consumption market. Despite of striction to Korean daramas by Chines government, new form of cooperation between two countries has been established in the form of buying entertainment programs and co-work for dramas and other entertainment programs. The new way of cooperation and purchasing popular program from Korea signify that culture is not an object of control by policy but a global phenomenon. And competitiveness in culture cross the frontiers and stimulates mutual development without being shaped by political policies. The Korean government and those who work in an area of cultural industry should prepare new alternatives in case of being a scapegoat of cultural policy by Chinese government in a period of hot politic with cool cultural relationship between Korea and China.

모시 소재의 문양에 따른 감성 이미지 평가

이순임 ( Soon Im Lee ),김재숙 ( Jae Sook Kim ) 服飾文化學會 2006 服飾文化硏究 Vol.14 No.6

다년생 논잡초의 발생밀도에 따른 벼의 생육, 수량 및 감수 예측모델

이순계(Sun Gye Lee),김도순(Do Soon Kim),임일빈(Il Bin Im),변종영(Jong Yeong Pyon) 韓國雜草學會 2005 Weed&Turfgrass Science Vol.25 No.4

5-fluorouracil 이 근간이 된 화학요법에 실패한 진행성 위암에서 Docetaxel 과 Cisplatin 복합화학요법

이효락(Hyo Rak Lee),박세훈(Se Hoon Park),송서영(Seo Young Song),박준오(Joon Oh Park),이순일(Soon Il Lee),김기현(Ki Hyun Kim),김원석(Won Seog Kim),정철원(Chul Won Jung),임영혁(Young Hyuck Im),이홍기(Hong Ghi Lee),박근칠(Keun Chil Park 대한내과학회 2002 대한내과학회지 Vol.62 No.1

N/A Background: There is no effective treatment in patients with advanced gastric cancer failed to first-line chemotherapy. Taxane is one of new drugs identified as having substantial activity in gastric cancer. We performed a phase II trial to evaluate the efficacy and toxicity of docetaxel plus cisplatin regimen as a salvage chemotherapy for advanced gastric cancer failed to 5-fluorouracil (5-FU)-based chemotherapy. Methods: Metastatic or recurrent gastric cancer patients failed to 5-FU-based regimen with an Eastern Cooperative Oncology Group (ECOG) performance score≤2 were eligible in this trial. Docetaxel (60mg/㎡) was infused over 1 hour , before cisplatin (60 mg/㎡) infused over 2 hours on day 1, once every 3 weeks until disease progression or unacceptable toxicity was detected. Response to treatment was assessed every two or three cycles. Results: From October 1999 to December 2000, forty-one patients were enrolled in this study. Twenty-eight of forty-one patients were assessable for response. Partial response was observed in seven patients and stable disease in four patients. The response rate was 25.0% (95% confidence interval: 20.4-29.6%) and median duration of response was 22 weeks (range: 11-53 weeks). The median survival of all enrolled patients was 24 weeks (range: 7-65 weeks). For a total of 112 cycles of chemotherapy, grade 3 and 4 toxicity was 8.9% for neutropenia, 4.5% for nausea/vomiting and 1.8% for mucositis. Conclusion: Salvage chemotherapy with docetaxel plus cisplatin regimen in gastric cancer was active with acceptable toxicities. (Korean J Med 62:83-89, 2002)

위암 조직내 Thymidylate Synthase 의 발현정도가 예후에 미치는 영향

남은미(Eun Mi Nam),임석아(Seock Ah Im),이순남(Soon Nam Lee),구혜수(Hea Soo Koo) 대한내과학회 1999 대한내과학회지 Vol.56 No.3

N/A Objective : Gastric carcinoma is one of the most common cause of death in Korea with limited effectiveness of chemotherapy. Thymidylate synthase(TS) is a critical therapeutic target for the fluoropyrimidine cytotoxic drugs, that are the mainstay of the treatment for the advanced gastrointestinal malignancies. We assessed the relationship between the levels of TS expression and survival and effect of 5-fluorouracil based chemotherapy in gastric adenocarcinoma. Methods : Thirty six patients with gastric adenocarcinoma who underwent curative resection of stomach at Ewha Womans University Hospital were evaluated. TS protein expression in tumor tissues was assessed by standard immunohistochemical staining techniques with TS 106 monoclonal antibody. Results : TS expression was high(3+) in 19 patients (52.8%) and low(≤2+) in 17 patients(47.2%). Between these two groups, there was no significant difference in the histopathologic type or stage. Seventy-two point five percent of patients with low TS expression were disease free at 5 years compared with 58.2% of patients with high TS expression(p=0.31) and 73.7% of patients with low TS expression were alive at 5 years compared with 61.4% of patients with high TS expression(p=0.34). In patients with high TS expression, disease-free survival (DFS) and overall survival(OS) of patients who received adjuvant chemotherapy were longer than those of patients with surgery alone without significance(p=0.28, p=0.16). Conclusions : We could not confirm the association between the level of TS expression in tumor tissues and DFS and OS of patients with gastric adenocarcinoma who underwent curative resection. Further study with more cases as well as prospective study will be necessary for establishment of relationship between TS expression of tumor and prognosis of gastric adenocarcinoma

서울지역 산업장의 보건관리

정연강,박신애,이나미,윤순녕,김영임,왕명자,이순남,김은희,고영애,Jung, Yeun-Gang,Park, Shin-Ae,Lee, Na-Mi,Yoon, Soon-Young,Kim, Young-Im,Wang, Myoung-Ja,Lee, Soon-Nam,Kim, En-Hee,Ko, Young-Ae 한국지역사회간호학회 1993 지역사회간호학회지 Vol.4 No.1

The objective of this study was to analyze the status of health examination, and the health care management of industries in Seoul. This will provide effective industrial health care services. 46 industries were selected as a sample, and were given self administered questionnaire developed by the academic affairs of community health nursing. The results of this study are as follows: (1) The general characteristics of industries: The greater part of the industries were manu facturing companies, 300-900 workers, in a one shift system. (2) The general characteristics of health man ager: 96% of the companies had industrial nurses and the larger industries had comprehensive health managers. 90% of the industrial nurses were full-time employees and 77% of the industrial physician were part time employees. 80% of the industrial physician were age 50 or older, while 59% of the industrial nurses were 25-29 years of age. (3) Health examination and follow up care: The proportions of the workers who took general health examination was 94%. Of those, 12% took secondary examinations. In secondary examinations, 36% were evaluated at the C-grade, 20% were evaluated at the D-grade. The proportion of the workers who were required to take special examination were 29% and of that, the proportion of the workers who actually took the examination was 88%. 85% of the workers who were recommended for follow up cares were given follow up care while working. The physical agents among the special examination were done the most frequently to detect the examination effects. (4) Health care services: Industrial nurses performed health examination most frequently and health education was done the least. There were significant differences in health care services according to the size of the industries. Companies with 300 workers or less had higher health care services than other groups. The three primary reasons of health care management and examinations of workers are: First, industrial nurses are requires to accumulate professional knowledge and experience through continuos' activities. Second, systematic and concert examination for industrial workers should be performed periodically. Third, it needs developing health education strategies that are important workers for health promotion in industries.

서울지역 산업장 근로자의 산업보건관리에 대한 지식, 태도, 실천 연구

정연강,박신애,이나미,윤순녕,김영임,왕명자,이순남,김은희,고영애,Jung, Yeun-Gang,Park, Shin-Ae,Lee, Na-Mi,Yoon, Soon-Young,Kim, Young-Im,Wang, Myoung-Ja,Lee, Soon-Nam,Kim, En-Hee,Ko, Young-Ae 한국지역사회간호학회 1993 지역사회간호학회지 Vol.4 No.2

This research is undertaken for the purpose of providing basic data to improve the occupational health service for future. 415 workers of 46 firms in Seoul are included in this data points. Results from this analyzing are the following. 1) The level of knowledge, attitude and practice of workers on the occupational health is moderate. 2) The cognition of necessity about special health examination gains the highest point(3.94), but the understanding of the occupational health educational program gains the lowest point (.85) in the knowledge region. 3) In the attitude region, the highest point is marked by the workers' prudence of expending time on medical examination(3.45). The lowest one by the workers' feeling of satisfaction of the follow-up service after medical examination(1.79). 4) The workers' participation in medical examination is the most active(3.15), and that in occupational health education in the least active(.86) in the practical region.

Lactobacillus plantarum CECT 7527, 7528, 7529 혼합물이 고지방식이를 급여한 흰쥐의 비만 및 지질 대사에 미치는 영향

김대환(Dae Hwan Kim),최미란(Mi-Ran Choi),홍지은(Ji Eun Hong),이재용(Jae-Yong Lee),이순임(Soon Im Lee),정수환(Su Hwan Jung),김은지(Eun Ji Kim) 한국식품영양과학회 2014 한국식품영양과학회지 Vol.43 No.10

본 연구에서는 고지방식이 투여로 비만 및 고지혈증을 유도한 동물에서 L. plantarum CECT 7527, 7528과 7529 혼합물이 비만 및 고지혈증에 미치는 영향을 조사하고자 하였다. 흰쥐에 8주 동안 고지방식이를 급여하면서 L. plantarum 혼합물을 0.6~2.4×10<SUP>9</SUP> CFU/day를 경구 투여하였고 동물을 희생하여 혈청 및 간조직 내의 지질 함량을 조사하였다. L. plantarum 혼합물 투여에 의해 체중증가량, 간과 부고환지방 무게가 현저히 감소하였다. 또한 비만과 관련 있는 호르몬인 혈청 렙틴의 함량이 L. plantarum 혼합물 투여에 의해 감소하였다. L. plantarum 혼합물 투여가 혈청 중성지방과 HDL-콜레스테롤 함량 및 혈당에는 영향을 미치지 않았으나 혈청 총콜레스테롤 함량 및 LDL-콜레스테롤 함량을 현저히 감소하였다. 이와 더불어 L. plantarum 혼합물 투여가 동맥경화지수와 심혈관위험지수를 유의적으로 감소하였다. 간조직 내의 총 지질 함량, 중성지방 함량 및 총콜레스테롤 함량은 L. plantarum 혼합물 투여에 의해 유의적으로 감소하였다. 이상의 결과는 L. plantarum CECT 7527, 7528과 7529가 혼합된 L. plantarum 혼합물이 체지방 감소 및 고지혈증 개선 효과를 나타냄을 보여준다. 향후 더 많은 연구가 필요하나 본 연구는 L. plantarum 혼합물을 비만 및 고지혈증 개선제로 개발할 수 있는 가능성을 제시한다. In the present study, we examined the effects of a mixture of three strains, Lactobacillus plantarum CECT 7527, 7528, and 7529 (L. plantarum mixture), on body weight and lipid metabolism in Sprague-Dawley rats fed a high-fat diet. Rats were fed a high-fat diet and subjected to oral gavage with vehicle or the L. plantarum mixture (0.6×10<SUP>9</SUP>, 1.2×10<SUP>9</SUP>, 2.4×10<SUP>9</SUP> colony-forming units (CFU)/day/rat, respectively) for 8 weeks. In rats fed a high-fat diet, oral administration of 2.4×10<SUP>9</SUP> CFU/day of the L. plantarum mixture significantly reduced body weight gain as well as weights of liver and epididymal fat. Leptin levels in sera were significantly reduced by oral administration of 2.4×10<SUP>9</SUP> CFU/day of the L. plantarum mixture. The L. plantarum mixture (1.2×10<SUP>9</SUP> or 2.4×10<SUP>9</SUP> CFU/day) also reduced the concentrations of total cholesterol and LDL-cholesterol in sera when it administered orally. Further, the L. plantarum mixture significantly reduced the atherogenic index and cardiac risk factor. In addition, oral administration of 2.4×10<SUP>9</SUP> CFU/day of the L. plantarum mixture markedly reduced levels of total lipids, triglycerides, and total cholesterol in the liver. The results of this study indicate that the L. plantarum mixture may exhibit anti-obesity and cholesterol-lowering effects, which suggest that the L. plantarum mixture has the potential to be a probiotic in the management of obesity and hypercholesterolemia.