국내 노인 심부전 환자에서의 잠재적으로 부적절한 약물사용 현황에 대한 연구

배민경,이인향,윤정현 한국임상약학회 2014 한국임상약학회지 Vol.24 No.2

Oxidative DNA Damage Response in Helicobacter pylori-Infected Mongolian Gerbils

배민경,김혜영,임주원 대한암예방학회 2013 Journal of cancer prevention Vol.18 No.3

Helicobacter pylori (H. pylori) induced DNA damage which may be related to gastric cancer development. The DNA damage res-ponse coordinates DNA repair, cell-cycle transition, and apoptosis through activation of DNA damage response molecules. The damaged DNA is repaired through non-homologous end joining (NHEJ) or homologous recombination (HR). In the present study, we investigated the changes of HR DNA repair proteins (ataxia-telangiectasia-mutated; ATM, ATM and Rad3-related; ATR), NHEJ repair proteins (Ku70/80), cell cycle regulators (Chk1, Chk2), and apoptosis marker (p53/p-p53) were determined in H. pylori- infected Mongolian gerbils. In addition, the effect of an antioxidant N-acetylcysteine (NAC) on H. pylori-induced DNA damage response was determined to assess the involvement of oxidative stress on DNA damage of the animals infected with H. pylori. One week after intragastric inoculation with H. pylori, Mongolian gerbils were fed with basal diet with or without 3% NAC for 6 weeks. After 6 week, the expression levels of DNA repair proteins (Ku70/80, ATM, ATR), cell cycle regulators (Chk1, Chk2) and apoptosis marker (p-p53/p53) were increased in gastric mucosa of Mongolian gerbils, which was suppressed by NAC treatment. In conclusion, oxidative stress mediates H. pylori-induced DNA damage response including NHEJ and HR repairing processes, cell cycle arrest and apoptosis in gastric mucosa of Mongolian gerbils.

부산지역 건설산업 활성화를 위한 정책 및 제도 개선방안

배민경,이준상,허영기 한국건축시공학회 2010 한국건축시공학회지 Vol.10 No.5

As the local economy has become stagnant, various policies have been made to revitalize the enormous construction industry. However, it is difficult for these policies to achieve their objective, as the construction industry is not an island unto itself but is interconnected in complex ways with diverse other areas of the economy. Interviews and surveys were conducted with experts in Busan, in order to identify the causes of the stagnant economy in the local construction market. The main findings were as follows. First, cost reduction and realistic master plans are needed as a solution for the problems of the redevelopment housing plan. Second, the alleviation of the construction policy is also necessary in order to overcome the problems of not considering the local construction industry. Finally, vocational training and quality education are needed to address the low awareness of construction feasibility analysis and the lack of highly trained human resources. The results of the study will help efforts to revitalize the local construction industry, and will provide an opportunity to reconsider the differences between the experts on issues of the industry. 지역 경제가 침체됨에 따라 각종 정책은 거대한 건축산업을 활성화를 위해 제시되고 있지만, 건설산업은 여러 요인들이 복합 작용하므로 목적에 모두 부합하는 것은 어렵다. 본 연구는 부산지역 전문인들을 대상으로 인터뷰 및 설문조사를 실시하여 현지 건설 시장의 경기침체의 원인을 찾을 수 있었다. 주요 결과는 다음과 같다. 첫째, 원가절감 및 현실적인 마스터 플랜은 재개발 주택계획을 위한 해결책으로 필요하다. 둘째, 지역 건설산업을 고려하지 않은 수도권 중심의 정책 문제는 규제 완화가 필요하다. 마지막으로, 건설사업타당성 분석에 대한 낮은 인식과 전문인력 부족 문제는 교육을 통한 인력양성이 필요하다. 본 연구결과는 지역건설의 활성화 개선에 도움이 될 것이며, 전문인들의 인식 차이를 고려할 수 있는 계기가 될 것이다.

일본의 「유치원 교육실습」 사례보고

배민경 한국유아교육학회 2012 정기학술대회 논문집 Vol.2012 No.-

모바일게임의 여성캐릭터 선호도에 영향을 미치는 조형원리 연구

배민경 한국일러스트레이션학회 2018 일러스트레이션 포럼 Vol.19 No.56

The purpose of this study is to find out how the visual design principles affect female character preferences to mobile games based on their form, and to be utilized in future plans for female character design in mobile games. The research method conducted a survey of 10 selected female characters and explored the principles of visual molding that affects preference. Based on the survey results, the average comparison were made using the SPSS24.0 statistical package. The results of the study showed that when combined with the survey results, the emphasis on the focus on the visual elements of the form had the greatest impact on the preference to female characters of mobile games. Second, when looking at the results of the survey, it was revealed the emphasis on the contrast to form visual elements had the second largest effect on preference. Third, when comparing harmony with emphasis, emphasis has a greater effect on preference than harmony. Fourth, the physical characteristics of female characters were emphasized on the focus on the visual elements of the form and through the emphasis through the preparation of the visual elements of the form. Therefore, it appears that a design with partially complex forms visual elements and an emphasis on women’s physical characteristics is preferred. 본 연구의 목적은 형태를 중심으로 모바일게임의 여성캐릭터 선호도에 어떠한 조형원리가 영향을 끼치는지 알아보는 것이다. 그리고 향후 모바일게임의 여성캐릭터 디자인에 활용될 수 있는 자료를 제공하는 것이다. 연구방법은 선정된 10개 여성캐릭터를 중심으로 전문가 설문조사를 실시하여 선호도에 영향을 미치는 조형원리를 알아보았다. 본 연구는 설문조사 결과를 바탕으로 SPSS 24.0 통계패키지를 이용하여 평균비교를 실시하였다. 연구결과는 첫째, 조사결과를 종합하여 살펴보았을 때, 형태시각요소의 ‘집중을 통한 강조’가 모바일게임 여성캐릭터의 선호도에 가장 큰 영향을 미치는 것으로 나타났다. 둘째, 조사의 결과를 종합하여 살펴보았을 때 형태시각요소의 ‘대비를 통한 강조’가 선호도에 두 번째로 큰 영향을 미치는 것으로 나타났다. 셋째, 크게 ‘조화’와 ‘강조’로 묶어 비교해 보았을 때, ‘강조’가 ‘조화’에 비해 선호도에 미치는 영향이 큰 것으로 나타났다. 넷째, 형태시각요소의 ‘집중을 통한 강조’와 형태시각요소의 ‘대비를 통한 강조’를 통하여 여성캐릭터의 신체적인 특징이 강조되었다. 따라서, 부분적으로 복잡한 형태시각요소를 가지며 여성의 신체적 특징이 강조되는 디자인이 선호되는 것으로 보인다.

스티커 북에 나타난 공주 캐릭터의 컬러 이미지 연구

배민경 한국일러스트레이션학회 2018 일러스트레이션 포럼 Vol.19 No.54

In the culture of infants and children, ‘Princess’ is one of the most preferred characters. From picture books to cosmetics to writing instrument sets, characters related to ‘Princess’ are also used. In this study, a sticker book was selected as a medium with a variety of Princess characters. This study aims to determine the overall color application of princess characters used in sticker books and to determine the major color image adjectives of princess characters. the results of this study are as follows: First, the section of color image adjectives that appear to be the most frequent in the princess character was found to be “clear”. Second, in the case studies and surveys, “cheerful” ranked second in each of the color image adjective sections, showing similar importance. Third, in the case of the “cute” section, the difference in importance is made explicit about the case studies and in the results of the survey. Fourth, the above three integration results show that each area of soft and dynamic is concentrated at a certain level. The results of the case study and the results of the survey did not deviate significantly from the generally recognized color image of the princess. It goes to show that when creating a princess character, people have a fixed perception of her. Lately, there have been several stories about princesses with different characteristics, such as Elsa, who broke through her way by shouting “Let it Go”, Let’s hope the colors of the princess’ characters will also escape from their fixed perception and be able to tell a variety of stories in this trend. We hope this study will be useful in making princess characters of the future. 유아 및 아동의 문화에서 ‘공주’는 가장 선호도가 높은 캐릭터 중의 하나이다. 그림책에서부터 화장품, 필기구 세트에 이르기까지 그 종류도 다양하게 ‘공주’와 관련된 캐릭터들이 사용되어 지고 있다. 본 연구는 공주 캐릭터가 다양하게 나타난 매체로서 스티커 북을 연구대상으로 잡았다. 본 연구는 스티커 북에 사용된 공주 캐릭터의 전반적인 컬러 적용 현황을 파악하고, 이를 통해 공주 캐릭터의 주요 컬러 이미지 형용사를 파악하는 것에 목적이 있다. 본 연구의 결과는 다음과 같다. 첫째, 공주 캐릭터에서 가장 높은 빈도로 나타난 컬러 이미지 형용사의 대분류는 ‘맑은’으로 나타났다. 둘째, 사례조사와 설문조사에서 ‘경쾌한’은 컬러 이미지 형용사 대분류에서 각각 2위를 차지하여 비슷한 중요도를 보였다. 셋째, 대분류에 속해 있는 ‘귀여운’의 경우, 사례조사와 설문조사상의 결과에서 중요도의 차이가 극명하게 나타났다. 넷째, 위 3가지 통합 결과, 부드러운(Soft)과 동적인(Dynamic)의 각각의 영역에서 일정수준 분리되어 집중되어 있는 것으로 나타났다. 연구결과 사례분석 결과와 설문조사 결과는 일반적으로 알고 있는 공주의 색채이미지에서 크게 벗어나지 않았다. 이는 공주 캐릭터를 제작 시 사람들이 공주 캐릭터에 대해 가진 고정적 인식을 벗어나지 못함을 보여준다. 최근에는 다양한 성격을 가진 공주 이야기들이 생겨나고 있다. 이러한 트렌트 속에서 공주 캐릭터의 색채도 고정적 인식을 벗어나 다양한 이야기를 할 수 있기를 바란다. 본 연구가 향후 공주 캐릭터 제작 시 유용하게 쓰이기를 기대한다.

Beneficial Effects of Taurine on Metabolic Parameters in Animals and Humans

배민경,Kainat Ahmed,임정은 대한비만학회 2022 Journal of obesity & metabolic syndrome Vol.31 No.2

Taurine (2-aminoethanesulfonic acid) is a non-essential amino acid mainly obtained through diet in humans. Despite the lack of research on the health effects of taurine in animals and humans, it is widely used as a dietary supplement. Evidence from human and animal studies indicates that taurine is involved in conjugation of bile acids and regulation of blood pressure and has anti-oxidative, anti-inflammatory, and anti-obesogenic properties. Taurine can benefit both human and non-human animal health in multiple ways. However, few interventional and epidemiological studies regarding the beneficial impacts of taurine in humans and other animals have been conducted. Here, we review the evidence from animal and human studies showing that taurine protects against dyslipidemia, obesity, hypertension, and diabetes mellitus.

주거환경만족도에 영향을 미치는 도시의 지역적 특성에 관한 연구

배민경(Bae, Min-Kyung),박승훈(Park, Seung-Hoon) 한국주거환경학회 2018 주거환경(한국주거환경학회논문집) Vol.16 No.2

Unlike in the past, housing styles and characteristics have gradually diversified. Therefore, there is a growing interest in residential environments that can meet people"s needs beyond housing supply. The subjective satisfaction of the residents is the main factor for the sustainable development of the city. Therefore, this study aims to suggest implications for improving the satisfaction of residential environment through the empirical study. The 2014 housing survey data and GIS data were used for analysis. As a research method, multi - level logistic regression analysis was used to analyze the influence of individual level and local level on the satisfaction of residential environment. As a result of the study, The more you stay in an apartment, the higher the overall satisfaction of the house. The higher the locational satisfaction, the higher the satisfaction of residential. In the second level of local variables, bus stops, libraries, and large commercial facilities showed a significant relationship. Through this study, various factors affecting the satisfaction of residential environment were identified. It also suggests that the planned supply and operation of the municipal infrastructure is necessary for residential satisfaction and housing welfare.

OCR 기반 시각장애인을 위한 편의점 음료 구입 보조 시스템

배민경(Bae Min-Kyeong),서현아(Seo Hyun-A),이영우(Lee young-woo) 한국콘텐츠학회 2021 한국콘텐츠학회 종합학술대회 논문집 Vol.2021 No.8

무단횡단 교통사고를 유발하는 가로환경요인에 관한 연구

배민경(Bae, MinKyung),박승훈(Park, SeungHoon) 한국지역개발학회 2018 韓國地域開發學會誌 Vol.30 No.2

Jaywalking, which is an illegal act crossing a road without a crosswalk, has been considered as a serious urban safety problem for a long time. 40.1% of traffic accidents causing death took place while walking. However, There are less studies that pay attention to the relationship between jaywalking and pedestrian collisions. Therefore, in this study, this study tries to analyze the street physical environments affecting traffic accidents occurred around the jaywalking hot spot. The data of pedestrian crashes was based on the TAAS data of the Road Traffic Corporation from 2010 to 2015. In addition, a spatial regression analysis was performed by constructing variables such as road structure, landscaping facilities, and walking-causing facilities. The OLS, SEM and SLM models were compared and the SEM model had the strongest explanatory power. As a result of the analysis, crosswalks with traffic lights increased the jaywalking accidents. Also, so-ro, dae-ro, underground sidewalks, bus stop density, and development density had a statistical significance with the pedestrian collisions. This study suggests the necessity of intensive and empirical study of jaywalking accidents for better pedestrian safety. It is possible to make an effective policy development to reduce the jaywalking, which is a urban safety problem, and to plan a pedestrian-safety city out of the vehicle-centered city.