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      • KCI등재

        Modification of Nafionr Using 3-mercaptopropyl Trimethoxysilane

        박용일,이혜정,박성범,오명훈,조경식,Satoshi Suzuki,Masayuki Nagai,Fritz B. Prinz 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4

        The modification of a Nafionr membrane by incorporation of 3-mercaptopropyltrimethoxysilane (MPTS) is investigated through a simple sol-gel process to reduce the methanol crossover without sacrificing the proton conductivity. The MPTS monomers incorporated in the Nafionr matrix are hydrolyzed, forming a silicate phase by polymerization. The thiols of MPTS are finally oxidized into a sulfonic acid form. Compared to Nafionr, the obtained modified membranes show significantly reduced solvent uptake with an accompanying low volume expansion ratio. A maximum 42% methanol crossover reduction is observed with improved proton conductivity. The proton conductivities of the obtained membranes increase from 8.0 × 10−3 Scm−1 to 1.9 × 10−2 Scm−1 at 70 ℃ with increasing MPTS amount from 0 to 1.96 wt%. The low methanol crossover and the high proton conductivity of the modified membranes are attributable to the MPTS-derived silicate phase blocking the ionic cluster pathway and to the simultaneous supply of a high sulfonic acid concentration to the Nafionr matrix.

      • KCI등재

        Evaluation of Possible Predictive Variables for the Outcome of Shock Wave Lithotripsy of Renal Stones

        박용일,유지형,성락희,노충희,정재용 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.10

        Purpose: The aim of this study was to evaluate possible predictive variables for the outcome of shock wave lithotripsy (SWL) of renal stones in a single center. Materials and Methods: Between March 2008 and March 2010, a retrospective review was performed of 115 patients who underwent SWL for solitary renal stones. The patients’ characteristics and stone size, location, skin-to-stone distance (SSD), and Hounsfield units (HU) of stone were reviewed. The impact of the possible predictors on the disintegration of the stones was evaluated by logistic regression analysis. Receiver operator characteristic (ROC) curves were generated to compare the predictive powers of the variables. Results: Seventy-nine patients (68.7%) had successful outcomes, whereas 36 patients (31.3%) had residual stones. Significant differences were found in the mean size and mean HU of the stones (size: 8.34±3.58 mm vs. 13.57±5.41 mm, p<0.001; HU: 675.29± 254.34 vs. 1,075.00±290.41, p<0.001). In the unadjusted model, age, stone size, and stone density were significant predictors. In the reduced model, stone density and size were significant predictors for the outcome of SWL. The area under the ROC curve (AUC) was significantly higher for stone density and size than for the other parameters, but the AUC between stone density and size did not differ significantly (stone density: 0.874, stone size: 0.827, p=0.388). Conclusions: Stone density and size were significant predictors of the outcome of SWL for renal stones less than 2.0 cm in diameter. We should consider HU and stone size when making decisions on the treatment of renal stones.

      • KCI등재

        Preparation of Medium-Molecular Weight Chitosan and Its Antimicrobial Activity on Methicillin-Resistant Staphylococcus aureus

        박용일,문혜란,김성욱,박제권 한국키틴키토산학회 2010 한국키틴키토산학회지 Vol.15 No.1

        Medium-molecular weight chitosans (MMCs), ranging from 60 to 800 kDa, was prepared by enzymatic digestion of high molecular weight of native chitosan using crude enzyme solution containing chitosanolytic activity obtained from germinated barley. MMCs were compared with chitosans of different molecular weight, water-soluble glycol chitosan, and intact fucoidan known as sulfated polysaccharide and its oligosaccharides for their antimicrobial activities against the Gram-positive methicillinresistant Staphylococcus aureus (MRSA), and two Gram-negative bacteria Psedomonas auruginosa and Salmonellar spp (CCARM 8009). One of MMCs, named as MMC-P1 (63.8 kDa ), at 50 μg/ml of minimum inhibitory concentration (MIC)showed the most significant antimicrobial activities in a dose-dependent manner against MRSA, but negligible against P. aeruginosa and Salmonellar spp (CCARM 8009). Although native chitosan with positively charged NH3+groups in diluted acidic solution showed considerable antimicrobial activities when these bacteria were treated at high concentration of chitosan (1mg/ml), no significant inhibitory effect of native chitosan, glycol chitosan, intact fucoidan or its oligosaccharides was observed at the minimum inhibitory concentration (MIC) of MMC-P1. These results suggest that specific molecular weight of chitosan may be dominant factor directly affecting on antimicrobial activity especially against MRSA.

      • Filter-free luminescence diagnostics using upconverting nanoparticles

        박용일 한국공업화학회 2016 한국공업화학회 연구논문 초록집 Vol.2016 No.0

        We report a new detection method that obviates the need for filters and is much more sensitive since the target signal can be integrated. This approach exploits the unique optical properties of upconverting nanoparticles (UCNP). Optically excited UCNP emits long lifetime (several milliseconds) luminescent light even when the exciting light is turned off. This feature enables filter-free imaging of the particles by time-gated fluorescence imaging. Importantly, the method eliminates the interference from excitation light and short-lived background autofluorescence, which significantly improves the signal-to-noise ratio. We expect this portable and sensitive time-gated imaging system is applicable for detecting disease markers.

      • KCI등재

        Acute Idiopathic Hemorrhagic Pericarditis with Cardiac Tamponade as the Initial Presentation of Acquired Immune Deficiency Syndrome

        박용일,박성원,김현태,이보라,곽예경,조욱현,최석구,서정주 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.2

        This paper presents a case of cardiac tamponade with idiopathic hemorrhagic pericarditis as the initial symptom of human immunodeficiency virus (HIV) infection. A 29-year-old male came to the emergency room with a sudden onset of dizziness. Upon arrival, he was hypotensive although not tachycardic, and his jugular venous pressure was not elevated. His chest X-rays revealed a mild cardiomegaly. Transthoracic echocardiography revealed a large amount of pericardial effusion with a diastolic collapse of the right ventricle, a dilated inferior vena cava with little change in respiration, and exaggerated respiratory variation of mitral inflow velocities, representing echocardiographic evidence of cardiac tamponade. After pericardiocentesis, his blood pressure improved to 110/70 mmHg without inotropics support. Serial 12-lead electrocardiograms during hospitalization revealed upwardly concave diffuse ST-segment elevation followed by a T-wave inversion suggestive of acute pericarditis. Pericardial fluid cytology and cultures for bacteria, mycobacteria, adenovirus, and fungus were all negative. HIV enzyme-linked immunosorbent assay (ELISA) was positive and confirmed by Western blot. The CD4 cell count was 168/mm3. Finally, the diagnosis of cardiac tamponade due to HIV-associated hemorrhagic pericarditis was made. It was concluded that HIV infection should be considered in the diagnosis of unexplained pericardial effusion or cardiac tamponade in Korea.

      • KCI등재

        일본어 교육을 위한 [-続ける]문의 구조와 의미 고찰

        박용일 한국외국어대학교 일본연구소 2011 日本硏究 Vol.48 No.-

        本稿では継続を表す日本語の[-続ける]文において[事件の反復]と[行為の反復]という二通りの意味が現れるという事実を示すと共に、このように現れる二通りの意味が[-続ける]文の構造とどのように係わっているのかを示した。このような結果を通してⅠ章で提起した(2a)のような[-続ける]文に対応する韓国語がなぜ(2b)と(2c)のような二通りの表現で現れるのかその理由を提示した。 (2) a. みんなが地下水を買い続けた。 b. 모두가 지하수를 계속 샀다. c. 모두가 지하수를 사기를 계속했다. 本稿の手順を具体的にまとめると、[-続ける]文に二つの意味が現れ得るという可能性を[-続ける]文と対応する韓国語の表現を通して確認し、実際[-続ける]文において[事件の反復]と[行為の反復]の意味が現れるという事実を観察した。また、[-続ける]文に現れるこのような二通りの意味が[-続ける]文の構造と係わっていることを示すために、受動文現象、[何も]と否定語現象、[おVになる]と主語現象を通して[-続ける]文が単文構造を持っているということを示すと同時に、受動文現象、[おVになる]と主語現象を通して[-続ける]文が複文構造を持っているということを示した。このような結果をもって[-続ける]文の二通りの構造と二通りの意味が相互どのような関係を持っているのかを日本語母語話者の手助けを借り、[-続ける]文が複文構造の場合は[事件の反復]と[行為の反復]の意味が両方現れるが、[-続ける]文が単文構造の場合は[行為の反復]の意味だけが現れるという事実を示した。 このような結果は、[-続ける]文(2a)に対応する韓国語がなぜ(2b)と(2c)の二通りに現れるのかという理由について、(2b)は[行為の反復]の意味を持っている単文構造であり、(2c)は[事件の反復]の意味を持っている複文構造であるため、(2a)が[行為の反復]の意味を持つ単文構造の場合は(2b)と対応しており、(2a)が[行為の反復]や[事件の反復]の意味を持っている複文構造の場合は(2c)と対応していると説明することができる。

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