결절홍반양 피부 백혈병

김종우,윤영묵,김태형,김동석,김상원 ( Jong Woo Kim,Young Mook Yoon,Tae Hyung Kim,Dong Seok Kim,Sang Won Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.3

We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy. (Kor J Dermatol 1997;35(3): 556 - 560)

피부 B세포 림프종

김종우,윤영묵,김동석,김상원 ( Jong Woo Kim,Young Mook Yoon,Dong Seok Kim,Sang Won Kim ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2

We report a case of cutaneous B cell lymphoma in a 68-year-old male who had primarily developed two 2.0 * 2.0 * 0,6cm sized, dome shaped, dark red colored tumors on the medial side of his left thigh about 4 months previously. His general condition was good and laboratory results were within normal limits, except for the enlargement of aortocaval, paraaortic and left inguinal lymph nodes. Histopathological examinations revealed diffuse dense infiltration of large atypical cells with vesicular nuclei and large prominent nucleoli in the entire dermis. They were largely composed of centroblast and immunoblast-like cells and showed positive reactions to the leukocyte common antigen, and L26 and CD22 was related to peripheral B-cell lineage in the immunohistochemical study. The skin lesions improved completely with an m-BACOD regimen. There was no relapse over a 3-year follow-up period. (Kor J Dermatol 1997;35(2): 312-316)

정선지역 철광산에 분포하는 암석의 역학적 특성

김종우,박찬,김주환,허석,김동규,이동길,조영도,박삼규,Kim, Jong-Woo,Park, Chan,Kim, Ju-Hwan,Heo, Seok,Kim, Dong-Kyu,Lee, Dong-Kil,Jo, Young-Do,Park, Sam-Gyu 한국암반공학회 2015 터널과지하공간 Vol.25 No.3

본 연구에서는 최근 재개발되고 있는 정선지역의 철광산에서 현장 초기지압 시험과 수많은 암석 실내시험을 실시하였다. 본 광산의 측압계수는 심도가 깊어질수록 작아지는 경향을 보였으며 평균값은 1.10으로 나타났다. 본 광산에 주로 분포하는 네 가지 암종인 백운암, 규장암, 화강암, 철광석에 대한 실내시험을 통해 암석의 단위중량, 공극률, 흡수율, 탄성파속도, 일축압축강도, 영률, 포와송비, 인장강도, 쇼어경도, 내부마찰각, 점착력 등의 각종 역학적 특성을 조사하였다. 실내시험 결과의 통계분석을 통해 암종별 물성을 비교하였고 물성 상호간의 관련성을 검토하였는데, 철광석보다는 규장암이나 화강암의 강도특성이 더 컸으며 암석 물성 간의 일반적인 상관관계와는 반대되는 현상도 발견되었다. 또한 Mohr-Coulomb 파괴조건과 Hoek-Brown 파괴조건을 적용하여 네 가지 암석의 파괴조건을 해석하였다. In this study, both in-situ stress measurements and a lot of laboratory rock tests were conducted at a metal mine in Jeongseon, Korea. The stress ratio obtained from in-situ stress measurements showed a tendency to decrease according to depth below surface and its average value was 1.10. The mechanical properties such as unit weight, absorption ratio, porosity, elastic wave velocity, uniaxial compressive strength, Young's modulus, Poisson's ratio, tensile strength, shore hardness, friction angle and cohesion were investigated for the four different rocks mainly distributed at a studied mine, which were dolomite, felsite, granite and magnetite. The mechanical properties of the four different rocks were compared by means of statistical analyses, whereupon the felsite and the granite turned out to have more strength characteristics than the magnetite. The correlation of mechanical properties was also investigated, whereupon a few results against the general correlation were found out. The failure criteria of the four different rocks were finally discussed by means of both Mohr-Coulomb criterion and Hoek-Brown criterion.

공기 상태량에 대한 습공기 밀도 계산

김종우,Kim, Jong-Woo 대한기계학회 2014 대한기계학회 논문집. Transactions of the KSME. C, 산업기술과 혁신 Vol.2 No.2

지구를 둘러싸고 있는 대기의 하층 부분을 구성하는 기체를 보통 공기라 말한다. 지상 20km 이하에서는 그 성분이 거의 일정한 비율로 존재하며, 질소, 산소, 기타 혼합기체로 구성된다. 공기밀도란 단위 부피 중에 포함된 공기의 질량을 말한다. 공기는 거의 일정한 성분으로 조성된 혼합기체이지만, 수증기는 변동이 큰 성분의 하나이다. 같은 온도, 같은 압력에서는 습공기의 밀도가 건공기의 밀도보다 작다. 보통 밀도는 압력이나 온도 변화에 따라 변화된다. 따라서 풍량 계산에 사용되는 중요 인자인 공기 상태량에 따른 밀도 계산과정과 actual air flow 와 standard air flow 의 관계를 살펴 보고자 한다. Generally the lower part of the Earth's atmosphere, which is 20km above the ground, is called "air." The composition of this area is almost consistent consisting of nitrogen, oxygen, and other gases. Air density refers to the mass per unit volume of earth atmosphere. Though air is made of the mixed gases in a constant composition, the water vapor is one of the very changeable components. The density of moist air is lower than the dry one at the same temperature and pressure. As the density varies according to the pressure and temperature, this paper attempts to explore the main factors in the air quantity calculation by examining first the density calculation process according to the air property, and second the relation between the actual and standard air flow.

한국산(韓國産) 우유(牛乳)의 적정(適正) 살균조건(殺菌條件)에 관(關)한 실험적(實驗的) 연구(硏究) III. 고온살균처리(高溫殺菌處理)에 의한 우유(牛乳)의 화학적(化學的) 조성(組成) 및 미생물학적(微生物學的) 성상(性狀)의 변화(變化)

김종우,Kim, Jong Woo 충남대학교 농업과학연구소 1987 Korean Journal of Agricultural Science Vol.14 No.2

국산우유(國産牛乳)를 원료(原料)로 한 적정(適正) 살균조건(殺菌條件)을 검토(儉討)하기 위하여 원유(原乳)를 $70^{\circ}C$, $75^{\circ}C$, $80^{\circ}C$, $85^{\circ}C$, $95^{\circ}C$ 및 $100^{\circ}C$의 각온도(各溫度)에서 15초간(秒間) 가열살균(加熱殺菌)하고 처리유(處理乳)의 화학적(化學的) 조성(組成) 및 미생물학적(微生物學的) 성상(性狀)의 변화상태(變化狀態)를 시험(試驗)한 결과(結果)는 다음과 같다. 1. 고온처리유(高溫處理乳)는 가열온도(加熱溫度)의 상승(上昇)에 따라 pH가 저하(低下)하였고 단백질(蛋白質), 지방(脂肪), 유당(乳糖) 및 회분등(灰分等)은 변화(變化)가 거의 없었으며 Casein 태질소(態窒素)와 비단백태질소함량(非蛋白態窒素含量)은 증가(增加)하고 비(非)Casein 태질소(態窒素) 및 여과성질소함량(濾過性窒素含量)은 감소(減少)하였다. 2. Calcium함량(含量)은 원유(原乳)의 119.78mg/100g로부터 $75^{\circ}C$ 가열(加熱)에서는 111.86mg/100g, $100^{\circ}C$ 가열(加熱)에서는 106.24mg/100g로 감소(減少)하였으며 Vitamin C에 있어서는 원유(原乳)의 $1.37mg/m{\ell}$로부터 $75^{\circ}C$ 가열(加熱)에서는 $1.15mg/100m{\ell}$, $100^{\circ}C$ 가열(加熱)에서는 $0.94mg/100m{\ell}$로 감소(減少)하였고 인공소화율(人工消化率)에 있어서는 가열온도(加熱溫度)의 상승(上昇)에 따라 증가(增加)하였다. 3. 생균수(生菌數)는 $75^{\circ}C$ 가열(加熱)에서 $9.0{\times}10^3/m{\ell}$로, $100^{\circ}C$ 가열(加熱)에서는 $3.4{\times}10^2/m{\ell}$로 감소(減少)하였고 대장균(大腸菌)은 $70^{\circ}C$ 가열(加熱)에서 검출(檢出)되지 않았으며 내열성균(耐熱性菌), 호열성균(好熱性菌), 호냉성균(好冷性菌) 및 곰팡이, 효모수도 가열온도(加熱溫度)의 상승(上昇)에 따라 크게 감소(減少)하였다. 4. 고온살균처리유(高溫殺菌處理乳)의 보존시험(保存試驗) 결과(結果) $25^{\circ}C$ 및 $37^{\circ}C$에 있어서는 l일후(日後)에 응고(凝固)하였고 $4^{\circ}C$ 보존(保存)에 있어서는 10일(日)까지 산도(酸度), 일반조성분(一般組成分), 미생물수등(微生物數等)이 변화(變化)가 거의 없어 우수한 보존성(保存性)을 나타내었다. The raw milk produced in Korea was heated at $70^{\circ}C$, $75^{\circ}C$, $80^{\circ}C$, $85^{\circ}C$, $90^{\circ}C$, $95^{\circ}C$ and $100^{\circ}C/15sec.$. The changes in chemical composition and microbiological aspects of the milk were summarized as following results: 1. In high temperature pasteurized milks as the heat treatment increased, pH value decreased but protein, fat, lactose and ash did not show significant changes in their contents while casein nitrogen and non-protein nitrogen increased but non-casein nitrogen and filterable nitrogen decreased in their contents. 2. Calcium content of raw milk decreased from 119.79mg/100g to 111.86mg/100g at $75^{\circ}C$ and to 106.24mg/100g at $100^{\circ}C$. Vitamin C decreased from $1.37mg/100m{\ell}$ of raw milk to $1.15mg/100m{\ell}$ at $75^{\circ}C$ and $0.94mg/100m{\ell}$ at $100^{\circ}C$. Artificial digestibility increased as the heat treatment got higher. 3. Viable bacteria counts decreased from $9.0{\times}10^3/m{\ell}$ at $75^{\circ}C$ to $3.4{\times}10^2/m{\ell}$ at $100^{\circ}C$. Coliforms were not found at $70^{\circ}C$ and thermoduric bacteria, thermophiles, psychrotrophic bacteria, mould and yeast decreased rapidly as the heat treatment increased. 4. The results of Keeping quality test for high temperature pasteurized milk showed that the' milks preserved at $25^{\circ}C$ and $37^{\circ}C$ were clotted just after 1 day but the milk preserved at $4^{\circ}C$ showed good shelf life which did not have any deterioration in titratable acidity, microorganisms and com positions.

한국산(韓國産) 우유(牛乳)의 적정(適正) 살균조건(殺菌條件)에 관(關)한 실험적(實驗的) 연구(硏究) II. 저온살균처리(低溫殺菌處理)에 의한 우유(牛乳)의 화학적(化學的) 조성(組成) 및 미생물학적(微生物學的) 성상(性狀)의 변화(變化)

김종우,Kim, Jong Woo 충남대학교 농업과학연구소 1987 Korean Journal of Agricultural Science Vol.14 No.2

The results of experiment to find out the optimum pasteurization condition by heating from $50^{\circ}C$ to $70^{\circ}C$ at intervals of $5^{\circ}C$ and to review chemical composition, microbiological aspects and keeping quality were summarized as follows: 1. The milk sample pasteurized at $50-70^{\circ}C$ showed the decreased pH value from 6.55 to 6.42 while the contents of protein, fat, lactose and ash did not have significant changes. 2. Non-casein nitrogen and filterable nitrogen decreased while casein nitrogen and non protein nitrogen increased as the heat treatment increased. 3. The content of calcium and vitamin C decreased and artificial digestibility for the pasteruized milk increased from 14.07% to 20.00% by the heat treatment. 4. Milk pasteurized at $65^{\circ}C$ had viable bacteria counts $1.3{\times}10^4/m{\ell}$, coliforms negative, psychrotrophic bacteria $9.5{\times}10^2/m{\ell}$ and 99.0% pasteurization effect. 5. Milk pasteurized at $65^{\circ}C$ did not show significant changes in chemical composition and microbiological aspects at $4^{\circ}C$ in refrigerator. 국산우유(國産牛乳)의 적정(適正) 살균조건(殺菌條件)을 구명(究明)하고자 $50^{\circ}C$로부터 $70^{\circ}C$까지 $5^{\circ}C$ 간격으로 가열처리(加熱處理)하고 처리유(處理乳)의 화학적조성(化學的組成) 및 미생물학적(薇生物學的) 성상(性狀) 변화(變化)를 확인함과 동시(同時)에 처리유(處理乳)의 보존성(保存性)을 시험(試驗)한 결과(結果) 다음과 같다. 1. $50^{\circ}C{\sim}70^{\circ}C$의 가열처리(加熱處理)에 의하여 우유(牛乳)의 pH 6.55로부터 6.42로 감소(減少)하였으며, 단백질(蛋白質), 지방(脂肪), 유당(乳糖) 및 회분(灰分)은 함량(含量)이 별로 변화(變化)하지 않았다. 2. 가열온도(加熱溫度)의 상승(上昇)에 따라 비(非) casein 태질소(態窒素) 및 여과성질소량(濾過性窒素量)은 감소(減少)하였으며 casein 태질소(態窒素)와 비단백태질소(非蛋白態窒素)는 증가(增加)하였다. 3. 가열온도(加熱溫度)의 상승(上昇)에 따라 우유중(牛乳中)의 Calcium 및 Vitamin C는 감소(減少)하였으며 가열처리유(加熱處理乳)의 인공소화율(人工逍化率)은 처리전(處理前)의 14.07%로부터 20.00%로 증가(增加)하였다. 4. $65^{\circ}C$의 가열살균(加熱殺菌)에 의하여 생균수(生菌數)는 $1.3{\times}10^4/m{\ell}$, 대장균수(大腸菌數)는 음성(陰性), 호냉성균수(好冷性菌數)는 $9.5{\times}10^2/m{\ell}$를 나타냈으며 99%의 살균율(殺菌率)을 표시(表示)하였다. 5. $65^{\circ}C$에서 가열살균(加熱殺菌)한 처리유(處理乳)는 $4^{\circ}C$의 냉장보존(冷藏保存)에서 화학적조성(化學的組成) 성상(性狀)의 변화(變化)가 적었다.

불임남성에서 Acetylcarnitine이 정액지표에 미치는 영향

김종우,이재석,박정수,김원태,서주태,Kim, Jong-Woo,Lee, Jae-Seok,Park, Jeong-Su,Kim, Won-Tae,Seo, Ju-Tae 대한생식의학회 2004 Clinical and Experimental Reproductive Medicine Vol.31 No.3

Purpose: To determine the efficacy of $Carnitil^{(R)}$ (acetylcarnitine, Hanmi, Korea) therapy in idiopathic oligoasthenospermic men. Materials and Methods: Forty-four subfertile men with abnormal semen parameters were treated between March, 2003 and March, 2004 with 3 g of $Carnitil^{(R)}$ daily for 3 months. Changes in semen parameters were evaluated 3 months after this therapy. Results: The mean age was 34.2 years and the mean follow-up duration was 3.7 months. In asthenospemic patients (n=28), semen analysis before and after $Carnitil^{(R)}$ treatment showed an increase in volume ($2.64{\pm}1.65\;ml$ vs. $3.10{\pm}1.60\;ml$), motility ($35.1{\pm}17.7%$ vs. $45.9{\pm}20.4%$) and viability ($51.4{\pm}20.3%$ vs. $59.3{\pm}13.6%$) respectively. In oligoasthenospermic patients (n=16), semen analysis before and after $Carnitil^{(R)}$ treatment showed an increase in sperm count ($10.7{\pm}54.4\;million/ml$ vs. $38.4{\pm}32.5\;million/ml$) respectively. Conclusions: These results suggested that in idiopathic oligoasthenospermic men the empirical medical therapy with acetylcarnitine may be considered as primary treatment.

행위기반 제어 설계 및 2족 축구 로봇에의 적용

김종우,성영휘,Kim, Jong-Woo,Sung, Young-Whee 한국융합신호처리학회 2009 융합신호처리학회 논문지 (JISPS) Vol.10 No.1

전통적인 모델 기반 제어 방법은 로봇의 센서계로부터 유추한 현 상황과 로봇이 가지고 있는 주변 환경에 대한 모델을 비교하고 이를 토대로 정교한 경로 계획에 따라 로봇을 구동하는 방식이다. 이러한 방식은 로봇의 주변 환경이 바뀌거나 동적으로 변화하는 경우에는 적용하기 어렵기 때문에 미리 알려져 있고 고정되어 있는 환경이 아니면 로봇이 성능을 발휘하기가 어렵다. 이에 반하여 행위기반 제어는 로봇이 처해있는 주변 환경에 대한 모델이나 경로 계획에 의존하지 않고 로봇의 특정한 센서 출력에 대하여 특정한 행위를 즉각적으로 수행하도록 구성되어 있어서 비구조적인 환경이나 동적으로 변화하는 환경에서 로봇에 적용하기가 좋다. 본 논문에서는 로봇이 처한 상황에 따라서 행위를 달리하는 상황의존형 행위기반 제어 구조를 제안하고 이를 1:1 2족 축구 로봇에 적용하여 그 효용성을 보인다. The performance of the robot is very limited in the conventional model-based control methods when the environments around a robot are not structured or are varying dynamically. The reason for that is the methods are based on the model of the environments which is very difficult to match with the real environments and on a path planning which is complex and time-consuming. On the other hand, the behavior-based control methods are not dependant on the model of the environments nor a complex planning. In those methods, a specific behavior is coupled with a specific sensor output, so the response of a robot is quite reactive and timely in dynamic and unstructured environments. In this thesis, we propose a situation dependant behavior based control architecture, in which a robot may behave differently to the same sensor output depending on various situations. We also show some experimental results to show the feasibility of the proposed control architecture.

여과처리가 우유의 진애도 및 세균함량에 미치는 영향

김종우,김용국 ( Jong Woo Kim,Yong Kook Kim ) 한국축산학회 1977 한국축산학회지 Vol.19 No.4

To select milk filter cloths for farm milk filtering and to investigate the suitable condition of milk filter cloths, several textile fabrics (Table 1, Fig.1) were tested the effect of filtering by sediment tester, the time taken for filtering, the effect of filter cloths on bacterial number in milk by filtering and the possibility of contamination of bacterial in milk from filter cloths in case of nonsterilization of cloths. And the results obtained are summarized as follows. 1. The effect of filtering was much better with Galgari, Sochang and Kwangmok than Eunchosa and Mangsa and the time taken for filtering was faster with Eunchosa, Mangsa, Tongsia and Galgai than Sochang and Kwangmok. 2. By filtering milk with Sochang and Kwangmok, the bacterial number in milk was reduced more than with other cloths but when filter cloths was not sterilized effectively, more bacteria was contaminated to milk from milk residue in cloths with Sochang and Kwangmok. 3. It was concluded that filter cloth of synthetic like nylon and about 0.05㎟ openings was suitable for milk filter cloths.

시판(市販) 발효유(醱酵乳)의 미생물학적(微生物學的) 연구(硏究)

김종우,Kim, Jong-Woo 충남대학교 농업과학연구소 1978 Korean Journal of Agricultural Science Vol.5 No.2

시판(市販)되고 있는 발효유(醱酵乳)의 미생물학적(微生物學的) 성상(性狀)과 보존온도(保存溫度)에 따른 미생물(微生物)의 소장상태(消長狀態)를 확인(確認)하기 위하여 시판(市販) 발효유(醱酵乳)를 1978년(年) 7월(月)부터 10월(月)까지 수집(蒐集)하여 시험(試驗)한 결과(結果) 다음과 같은 결론(結論)을 얻었다. 1. 발효유중(醱酵乳中)에 함유(含有)된 생균수(生菌數)는 $50{\times}10^6$ 내지 $73{\times}10^7$, 유산균수(乳酸菌數)는 $40{\times}10^6$ 내지 $62{\times}10^7$였으며 대장균수(大腸菌秀)는 음성(陰性)을 나타내었다. 2. 발효유(醱酵乳)의 산도(酸度)는 0.468%~0.668%로서 대부분 기준(基準)에 달(達)하나 낮은 편이었다. 3. $5^{\circ}C$ 보존(保存)에서는 산도(酸度)의 변화(變化)가 거의 없었으며 $20^{\circ}C$ 보존(保存)에서는 평균(平均) 22.55%, $30^{\circ}C$ 보존(保存)에서는 평균(平均) 117.66%의 산도(酸度) 증가현상(增加現象)을 나타내었다. 4. 생균수(生菌數는) $5^{\circ}C$로 보존(保存)할 해 96시간(時間)에 이르기까지 큰 변화(變化)가 없었으며 보존온도(保存溫度)의 상승(上昇)에 따라 세균수(細菌數)는 24시한(時閒)까지 증가(增加)하다가 점차적(漸次的)으로 감소(減少)되었다. 5. 유산균수(乳酸菌數)는 $5^{\circ}C$로 보존(保存)할 때 가장 감소율이 적었으며 보존온도(保存溫度)가 상승(上昇)함에 따라 균수(菌數)는 현저하게 감소하였다. Extensive studies on the commercial fermented milks, which had been distributed over four months from July to October in 1978, were carried out for their microbial characterization including an investigation on the variations of bacterial populations under various storage conditions. 1. Total number of viable cells in the products were in between $5{\times}10^7$ cells/ml and $73{\times}10^7$ cells/ml, and $62{\times}10^7$ cells/ml, however no coliform bacteria were detected in the products. 2. Acidities of the products were not very high but fit in the standard as appeared to be in between 0.4869% and 0.6689%. 3. The acidities of the products showed little changes when stored at $5^{\circ}C$, but rises in 22.55% at $20^{\circ}C$ and in 117.66% at $30^{\circ}C$. 4. Total viable counts weren't varied much upto 96 hours when stored at $5^{\circ}C$, but increased during first 24 hours then decreased gradually at the higher temperatures. 5. Viable counts of lactic acid bacteria were decreased markedly with ascending the storage temperature, showing minimal variations when stored at $5^{\circ}C$.