출혈을 동반한 거대 위 신경초종 1예

김제연 대한위암학회 2006 Journal of gastric cancer Vol.6 No.1

박동진이 인식한 ‘현대건축의 추세’(1931)

김제연,김현섭 한국건축역사학회 2021 한국건축역사학회 학술발표대회논문집 Vol.2021 No.11

출혈을 동반한 거대 위 신경초종 1예

김제연,안지영,최민규,노재형,손태성,김성,Kim, Je-Yeon,An, Ji-Yeong,Choi, Min-Gew,Noh, Jae-Hyung,Sohn, Tae-Sung,Kim, Sung 대한위암학회 2006 대한위암학회지 Vol.6 No.1

위에서 생기는 점막하 종양은 내시경적 조직검사로는 그 기원을 알기 어려운 경우가 많다. 이러한 점막하 종양 중, 슈반 세포(Schwann cell)로부터 분화하여 생기는 종양을 신경초종(Schwannoma)이라고 하며, 위에서 생기는 전체 종양의 0.2%를 차지한다고 알려져 있다. 이 증례는 2개월 전부터 시작된 다량의 흑색변과 빈혈을 주소로 내원한 57세 여자 환자에 대한 보고이다. 복부 컴퓨터 단층 촬영 및 상부 위장관 내시경에서 위 분문에서 3 cm정도 아래부터 위각 직상부까지 위체부 소만을 대부분 차지하는 약 8 cm 이상의 돌출된 종양이 관찰되었고, 수 차례에 걸친 내시경적 조직검사를 시행하였으나 괴사조직과 육아종성 조직, 만성 위염 소견만 반복해서 나왔다. 출혈을 동반한 진행성 위암, 림프종 등을 생각하여 정확한 진단 및 출혈에 대한 치료를 위해 수술을 시행하였다. 술 후 조직검사에서 전반적으로 소엽상 형태(lobulating pattern)로 주변에 림프구 침윤(lymphocyte cuffing)이 있었고 책상핵(palisading nuclei), 방추세포(spindle-cell) 등이 보였다. C-kit, CD34, SMA 모두 음성이었으며 S-100 양성으로 신경초종으로 진단되었다. The origin of a submucosal tumor is difficult to determine by endoscopic biopsy. One type of submucosal tumor, which originates in Schwann cell, a schwannoma represents 0.2% of all gastric tumors. We experienced the case of a 57-year-old female patient with a gastric schwannoma presenting with melena and anemia. Computed tomography and upper gastrointestinal endoscopy showed a protruded huge mass from 3 cm below the cardia to angle. Seven endoscopic biopsies indicated only necrotic debri and granulation tissue, chronic gastritis. Because we suspected an advanced gastric cancer, or lymphoma with bleeding, It was performed an operation for an exact diagnosis and a treatment for bleeding. A-post-operative histopathological, immunohistochemical examination led to the final diagnosis of a gastric schwannoma.

Identification of Homozygous Likely Pathogenic Variant of ALDH3A2 in a Korean Boy with Sjögren–Larsson Syndrome

김제연,김신혜,박미정,김성희,조우호,최진,기창석,유수정 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.1

Dear Editor, Sjögren–Larsson syndrome (SLS; OMIM 270200) is an autosomal recessive disorder caused by deficiency of fatty aldehyde dehydrogenase (FALDH) owing to mutations in ALDH3A2 [1]. Patients with SLS usually have ichthyosis after birth, spastic paraplegia, and mental retardation. On ocular examination, crystalline macular dystrophy is often observed, which can result in photophobia or reduced visual sensitivity in affected patients [2, 3]. In Korea, there have been a few case reports on SLS but, as far as we know, none was confirmed by genetic testing [4-7]. Although some patients show typical clinical features of SLS, its phenotype can be variable so that genetic testing of ALDH3A2 should be performed to make a diagnosis of SLS. We present clinical and genetic findings of a Korean patient with SLS

절제한 액와 림프절과 전이된 림프절의 비율이 액와부 전이 유방암 환자의 재발과 전체생존율에 미치는 영향

김제연,임혜인,이세경,최재혁,김완욱,최준호,김정한,김지수,이정언,남석진,양정현 한국유방암학회 2008 Journal of breast cancer Vol.11 No.4

Purpose: The status of axillary lymph node (LN) metastasis is the most important prognostic factor in breast cancer. Postoperative regional nodal radiotherapy is recommended usually based on the number of metastatic LNs, which is associated with the total number of removed LNs during the axillary dissection. We evaluated the prognostic impact of the ratio of metastatic LNs to removed LNs on disease free survival and overall survival in breast cancer patients. Methods: The medical records of 743 breast cancer patients with metastatic axillary LNs and treated at Samsung Medical Center between 1994 and 2003 were retrospectively analyzed. The ratio of metastatic/removed LNs as well as the other prognostic factors were analyzed. Results: Both disease-free survival and overall survival rates were significantly worse in patients with a ratio of metastatic/removed LNs greater than 20% compared to those patients with a ratio of less than 20% (p=0.028, p<0.001, respectively). In patients with T1-2 and N1 breast cancer, the ratio of metastatic/removed LNs greater than 20% was significantly associated with poorer disease-free survival (p=0.027). Conclusion: A ratio of metastatic/removed LNs greater than 20% in the axilla can be an adverse prognostic factor in breast cancer patients with axillary node metastasis. In T1-2 N1 breast cancer patients, adjuvant radiotherapy as well as more aggressive chemotherapy therapy may be indicated.

진행성 위암의 수술 후 발견된 단독 간 전이에 대한 고주파 치료

김제연,안지영,최민규,노재형,손태성,김성 대한외과학회 2006 대한외과학회 학술대회 초록집 Vol.2006 No.5

Successful use of supraglottic airway in a professional singer undergoing laparoscopic living donor right hepatectomy - A case report -

김제연,김갑수,김덕경,신현수 대한마취통증의학회 2018 Anesthesia and pain medicine Vol.13 No.4

A 25-year old female singer was scheduled to undergo a right hepatectomy for her father’s liver transplantation. Her two main requests were rapid recovery and prevention of cosmetic complications, and the avoidance of postoperative laryngeal damage. Thus, we decided to use a laparoscopic surgical approach and the second-generation supraglottic airway (ProtectorTM supraglottic airway). After anesthetic induction, the supraglottic airway was placed at the first attempt, and its performance was tested using the oropharyngeal leak pressure and maximal minute volume ventilation tests. Throughout the surgery, the cuff pressure of the supraglottic airway was maintained in the green zone. The ProtectorTM supraglottic airway was successfully used during 300 minutes of anesthesia, and it only caused mild postoperative sore throat without hoarseness or aspiration. Anesthesiologists should consider using the supraglottic airway proactively in laparoscopic living donor right hepatectomies when professional voice users undergo surgery.

새 敎育 課程에 따른 高等學校 共通科學 敎科書 生命 單元의 比較 分析

김제연,신두철,김현섭 공주대학교 사범대학 과학교육연구소 1997 과학교육연구 Vol.28 No.1

本 硏究는 새 敎育 課程에 따른 高等學校 共通科學7種 敎科書 生命 單元의 知識 領域과 探究 領域을 定量的으로 比較·分析하여 高等學校 生物 敎育의 基礎 資料를 제공하고, 敎育의 效率性을 기하기 위하여 수행되었으며, 그 結果는 다음과 같다. 1. 生命 單元의 紙面 數는 7種 敎科書의 全體 平均 476.29面 중에서 附錄을 포함하여 13.20%인 62面 이었으며, 가장 많은 것은 E 敎科書로서 80面, B 와 C 敎科書는 63面, F 敎科書는 62面, D 敎科書는 60面, A와 G 敎科書는 가장 적은 55面이었다. 單元別로는 '刺戟과 反應'이 平均 14.3面으로 가장 많았고, '遺傳'이 平均 11面으로 가장 적었다. 2. 單元別 分量과 探究 活動 回數의 相對比를 調査하여 分析한 결과, '營養과 健康' 單元에서 相對比가 1.0으로 가장 적절하였다. 3. 探究 活動의 主題는 類似한 內容의 主題를 하나로 묶어서 調査했을 때 72種, 127回로 나타났으며, 7種 敎科書 모두에서 취급하고 있는 主題는 '사람의 遺傳 形質', '生殖 細胞 形成', '性호르몬의 分泌 調節' 등으로 학교 현장에서 반드시 다루어야할 必須 主題임을 알 수 있었다. 4. 探究 活動 回數와 각 內容 要素別 回數를 調査하여 分析한 결과, ㉮ 實驗 回數의 相對比는 '營養과 健康' 單元에서 1로 가장 적절한 回數를 나타냈다. ㉯ 資料解析의 相對比는 '生殖' 單元에서 1.41로 지나치게 높았으며, '刺戟과 反應' 單元이 0.94로 가장 적절한 回數이니 것으로 나타났다. ㉰ 調査의 相對比는 '遺傳' 單元이 1.11로 가장 적절한 回數인 것으로 나타났다. ㉱ 討議의 相對比는 '營養과 健康' 單元이 1로 가장 적절한 回數인 것으로 나타났다. 5. 探究 活動의 比重이 커짐에 따라 學校 現場에서 실제로 활용될 수 있는 主題 및 素材의 개발이 필요하며, 實驗과 觀察을 위한 충분한 시설이 갖추어 지고, 충분한 시간이 주어져야만 한다. 6. 學習者에게 探究 活動 中心의 수업이 될 수 있도록 敎科 內容의 양을 줄여야 한다. 또한 原理와 法則, 槪念 등의 이해를 돕고 興味와 刺戟을 줄 수 있는 그림, 읽을 거리, 揷畵, 寫眞 및 낱말 맞추기 등의 資料가 많아야 하고, 視覺的 效果의 極大化를 위하여 天然色으로 構成되어야 할 것이다. 7. 多樣하고 많은 數의 探究 活動을 제공하여 學生들의 興味를 誘發하고 地域的·季節的 與件, 學校 事情, 敎科上의 問題 등 여러 면에서 融通性 있게 운영할 수 있도록 하여야 한다. 8. 敎科書 分量에 비추어 受業 時數 單位 配當의 適正性에 대한 硏究가 수행되어야 할 것이다. 9. 共通科學 敎科書의 다른 單元 즉, 物理, 化學, 地球科學 및 環境 單元 등을 總括하여 7種 敎科書에 대한 比較·分析 硏究가 遂行되어 바람직한 高等學校 共通科學 敎育에 대한 改善 資料가 마련되어야 한다. The purpose of this study is to provide the basic information and efficiency for biology education through analysis and comparison of knowledge part and inquiry part of Life Unit on the seven kinds of the high school 'General Science' textbooks written in accordance with new curriculum. Especially this study is focused on analysis of the inquiry activity of the textbooks. The results obtained are summarized as follows: 1. The numbers of pages about the 'Life' unit are 62 including the appendix among the whole average 476.29 Textbook B and C fill pages the 'Life' unit 63, textbook F 62, textbook D 60. While textbook E contains the 'Life' unit more than any other book as the 80 pages, textbook A and G have the least pages 55. 2. On the basis of the result of analysis to relative rate between the quantity of units and the frequency of research activities, the optimum relative rate is found in the unit 'Nutrition and Health'. 3. Regarding subjects of the similar contents as one subject, the subjects of research activities are 72 kinds and frequency of experiments about them is 127. 'An inherited character of man', 'Controls of sex hormone secretion' and 'Formation of reproductive cells' are common subjects in the 7 different kinds of textbooks. We can know that they are necessary subjects which should be treated in school. 4. The results obtained from analyzing the frequency of research activities and units indicate that, ⓐ The relative rate of the frequency of experiments is 1 in the unit "Nutrition and Health" and the rate is the optimum frequency. ⓑ The relative rate of materials analysis in 1.41 in the unit 'Reproduction' and 0.94 in the unit 'Stimulus and Reaction'. While the former rate is excessively high, the latter rate is the optimum frequency. ⓒ The relative rate of inquiry is 1.11 in the unit 'Heredity' and the rate is also the optimum frequency. ⓓ The relative rate of discussion is 1 in the unit 'Nutrition and Health' and the rate is the optimum frequency. 5. As research activities are emphasized, the development of the subjects and the materials which really can be used in school is need. 6. The quantity of textbook contents have to be decrease for the students can do the research activities. The textbooks should have these materials such as pictures, photographs, something good to read, and puzzles··, etc, that can help students to understand principles, laws and conceptions and also to give students interests and simulations. The textbooks also should be made colorful to improve the visual effects. 7. The textbooks should have many kinds of research activities and various contents in order to give interests and motivation to students. They also have to be considered the conditions of regions, seasons, schools and scientific matters. 8. The study that the class time allotment set on the basis of the quantity of textbook should be performed. 9. General science textbook consists of different units such as 'Physics', 'Chemistry', 'Geoscience' and 'Environment'. As these units are generalized, compared and analyzed on the 7 different kinds of textbook, improving materials should be made for the desirable high school general science education.

단일 어안 카메라 기반 후방 장애물 높이 추정 방법

김제연(Jeyeon Kim),서재규(Jae Kyu Suhr),정호기(Ho Gi Jung),조훈(Hoon Jo),김회율(Whoi-Yul Kim) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.11

Generally, Stixel is based on a stereo camera, and used for the forward environment representation. This paper proposes monocular camera-based Stixel for the rear environment representation. In particular, this paper focuses on the obstacle height estimation using sparse disparity map. Disparity and appearance information is fused in this paper since the sparse disparity map acquired by motion stereo has little information compared to dense disparity map. Experimental results show that the proposed method can successfully estimate obstacle height in actual parking lots.

GAN 모델을 이용한 배터리 셀 불량 분석 기법에 관한 연구

김제연(Jeyeon Kim),박한규(Hangyu Park),윤혜수(Hyesu Yoon),강선경(Seongkyeong Kang) 한국정보통신학회 2022 한국정보통신학회 종합학술대회 논문집 Vol.26 No.2