성인 간호대상자 사정도구 개발에 관한 일 연구

김시현,정희섭,조학순 中央醫學社 1987 中央醫學 Vol.52 No.3

There was a certification of the substances, the objects, the main concepts, and the subjects of nursing as the result of movement to establish scientific system of the nursing after 1960s. According as the subjects of nursing was changed from disease itself and health problem of the past to human, we approached nursing problem by applying several nursing theories to offer special, individual, and scientific nursing to active nursing client. As that, more systemically nursing activity is tried, so the necessity of grasping the nursing client's nursing problem take place and the development of the assessment tool to appreciate the nursing problem is needed. Moreover, though nursing process is applied to make progress students clinical demonstration more completely, more detailed assess-ment tool is strongly required, so this study is attended. We thought that the assessment process certifying the nursing problem of nursing client of adult which is defined as the stage that mental and physical maturity of the human development stages is developed by many scholars should assess the degree of self care ability, so this study developed the assessment tool depended on Orem's Self Care theory by taking the merits of existing assessments tools through the investigation of many documents.

행복한 아이가 학업성취도가 높은가?: 초등학생의 행복감과 학업수행능력 간 자기회귀교차지연 효과검증

김시현 인하대학교 교육연구소 2022 교육문화연구 Vol.28 No.1

본 연구는 초등학생의 행복감과 학업성취 간의 인과관계를 규명하는 기존 연구가 주로 횡단자료에 의존하였기 때문에 엄밀한 인과관계를 규명하지 못한 한계를 극복하고, 종단자료를 사용하여 행복감과 학업성취도 중 어떤 변수가 원인으로서 작용하는지 면밀하게 규명하고자 하였다. 이를 위해 한국아동패널(Panel Study on Korean Children) 데이터의 9-11차년도(2016-2018) 자료를 사용하였으며, 자기회귀교차지연모형을 활용하였다. 본 연구의 분석 결과는 다음과 같다. 첫째, 아동의 행복감은 시간에 따라 안정적인 것으로 나타났다. 이전 시점의 행복감이 이후 시점의 행복감에 미치는 영향은 유의하였다. 둘째, 아동의 학업수행능력은 아동의 행복감과 같이 시간의 변화에 따라 안정적으로 나타났다. 셋째, 아동의 행복감이 학업수행능력에 미치는 영향과 학업수행능력이 행복감에 미치는 영향은 모두 유의하였 다. 교차지연계수를 보면 행복감이 학업수행능력에 미치는 영향이 조금 더 큰 것으로 나타났다. 넷째, 아동의 행복감과 학업수행능력 간 관계 경로의 남녀 간 차이는 유의하지 않은 것으로 나타났다. 본 연구는 기존의 이론과 논리를 바탕으로 인과관계를 설정하여 이에 따라 도출된 관계를 해석하는 기존 횡단연구의 한계를 극복하고, 두 변인간 관계를 자기회귀교차지연 모형을 통해 경험적으로 검증했다는 데 의의가 있다. 또한 초등학교 시기는 인지적 발달 및 다양한 심리적 발달이 이루어지는 중요한 시기로, 이 시기 아동의 행복감 및 학업수행능력 제고를 위한 시사점을 제시하였다.

수계에 인접한 목조건축물의 생물분포 모니터링 연구 - 여주 신륵사를 중심으로 -

김시현,이현주,이민영,정선혜,정용재 한국문화재보존과학회 2017 보존과학회지 Vol.33 No.4

여주 신륵사는 남한강과 인접하여 습도가 높고 안개일수가 많으며 산림과 인접하여 생물피해가 우려되는 곳이다. 이에 문화재 보존관리 계획 수립에 필요한 기초자료 확보를 위해 신륵사 목조건축물의 생물분포와 주변 산림의 흰개미 분포를 3년 동안 모니터링 하였다. 그 결과 문화재 가해곤충인 구멍벌이 지속적으로 확인되었으며, 계절과 연차별 곤충 분포가 다양하게 나타났다. 이는 대상지의 입지특성과 당해 연도의 기후 변화가 함께 반영되었기 때문으로 추정된다. 배후 산림에서는 전체적으로 흰개미 군체가 확인되었고, 분포 양상은 매년 다르게 나타났다. 미생물 조사 결과 건물의 출입 여부에 따라 종별 분포와 오염도가 다르게 나타났으며, 목재부후균도 분리·동정되었다. 따라서 보존환경과 생물분포에 대한 지속적인 모니터링과 함께 목재가해생물종의 추가적인 유입을 막기 위한 조치가 필요하다. The Silleuksa temple in Yeoju city is adjacent to the South Han River and often has high humidity and fog days. In addition, its proximity to forests renders it prone to damage by insects and microorganisms. In order to obtain the basic data necessary for the establishment of a cultural property preservation management plan, the biological distribution of the wooden buildings and the termite distribution in the surrounding forests were monitored for three years. The wood-boring bee, an insect known to inflict damage to heritage structures, was confirmed, and the distribution of insects varied annually and seasonally, presumably due to the location characteristics of the site and the climate change during the year. In the forest behind, termite colonies were identified as a whole and their distribution pattern was different every year. As per the results of the microorganism survey, the species distribution and pollution degree were different at the entrance of the building. Therefore, it needs continuous biological distribution and conservation environment monitoring to mitigate the effects of wood-damaging organisms.were different according to the entrance of the building.

OFDM 복조기의 개발을 위한 Front End 부 설계

김시현 水原大學校 2015 論文集 Vol.29 No.-

Orthogonal frequency division multiplexing (OFDM) has been accepted for a variety of wireless applications, such as digital TV, mobile communication, and wireless communication. The hard-wired OFDM demodulator is crucial for the low cost and low power solution. In this paper, the front end block of the hard-wired demodulator is developed. Since the design utilizes the cyclic prefix of the OFDM symbol, the correlation coefficient is a very strong indicator of the fractional frequency offset. From the simulation based experiment, the designed front end shows stable and robust intial frequency synchronization performance in the white gaussian and multipath fading channel.

Evaluation of DNA Extraction Methods and Their Clinical Application for Direct Detection of Causative Bacteria in Continuous Ambulatory Peritoneal Dialysis Culture Fluids from Patients with Peritonitis by Using Broad-Range PCR

김시현,정행순,김영훈,송새암,이자영,오승환,김혜란,이정녀,고원규,신정환 대한진단검사의학회 2012 Annals of Laboratory Medicine Vol.32 No.2

Background: The aims of this study were to compare several DNA extraction methods and 16S rDNA primers and to evaluate the clinical utility of broad-range PCR in continuous ambulatory peritoneal dialysis (CAPD) culture fluids. Methods: Six type strains were used as model organisms in dilutions from 108 to 100 colony-forming units (CFU)/mL for the evaluation of 5 DNA extraction methods and 5 PCR primer pairs. Broad-range PCR was applied to 100 CAPD culture fluids, and the results were compared with conventional culture results. Results: There were some differences between the various DNA extraction methods and primer sets with regard to the detection limits. The InstaGene Matrix (Bio-Rad Laboratories, USA) and Exgene Clinic SV kits (GeneAll Biotechnology Co. Ltd, Korea) seem to have higher sensitivities than the others. The results of broad-range PCR were concordant with the results from culture in 97% of all cases (97/100). Two culture-positive cases that were broad-range PCR-negative were identified as Candida albicans, and 1 PCR-positive but culture-negative sample was identified as Bacillus circulans by sequencing. Two samples among 54 broad-range PCR-positive products could not be sequenced. Conclusions: There were differences in the analytical sensitivity of various DNA extraction methods and primers for broad-range PCR. The broad-range PCR assay can be used to detect bacterial pathogens in CAPD culture fluid as a supplement to culture methods.

국내 지중흰개미의 목조건축물 유입 차단을 위한 모래의 적정 입도 연구

김시현,김태헌,정용재 한국문화재보존과학회 2022 보존과학회지 Vol.38 No.2

흰개미는 목조건축문화재의 주요 손상 원인 중 하나이며, 방제를 위해 살충제가 주로 사용되어 왔다. 흰개미 피해가 심한 국가들은 화학적 방제법의 대안으로 흰개미가 통과하지 못하는 망, 입자 등을 이용한 물리적 방어벽이 사용되고 있다. 본 연구에서는 물리적 방어벽의 적용을 위해 국내 전역에 서식하는 R. speratus kyushuensis의 유입을 차단하는 모래의 적정 입도 범위를 규명하고자 하였다. 0.85∼4.00 mm의 입도별 모래로 흰개미 유입 차단성을 평가한 결과 1.00∼2.80 mm 입도 조건에서 흰개미의 유입을 효과적으로 차단하였다. 이보다 작은 입도 조건 에서는 흰개미들이 모래 입자를 옮겨서 선형에 가까운 흰개미 길(mud tube)을 구축하여 모래층 을 관통하였으며, 이보다 큰 입도 조건에서는 흰개미들이 모래 사이의 공극을 지나다니는 방법 으로 모래층을 관통하는 양상이 확인되었다. Termites cause massive damage to wooden architectural heritage structures. Chemical treatments have been commonly used to control them. In foreign countries, physical barriers made of sheet and particles impenetrable to termite are being used as an alternative to the chemical method. To study the efficacy of physical barriers, we investigated the appropriate sand particle size that can prevent the penetration of R. speratus kyushuensis. Upon evaluating the barrier properties of sand with particle sizes ranging from 0.85 to 4.00 mm, the penetration of termites was found to be effectively blocked at a particle size range of 1.00 to 2.80 mm. At smaller particle sizes, termites managed to move the sand particles and build an almost linear mud tube to penetrate the sand layer. At larger particle sizes, the termites could penetrate the sand layer by passing through the sand gaps.

Classification Model to Discriminate People with and without Pain in the Lower Back and Lower Limb using Symmetry Data

김시현,정시우,박규남 KEMA학회 2021 근골격계과학기술학회 Vol.5 No.2

Background Multiple factors are associated with lower back and lower limb (LB & LL) pain, such as impaired muscle strength, balance, endurance, and motor control, and altered movement patterns. Symmetry of motion, strength and balance are goals for rehabilitation in patients with LB & LL pain. When classifying patients before or during on- and offline assessment, it is necessary that an easy to use functional test be available for clinicians. Purpose To establish a classification tree model for discriminating people with and without LB & LL pain during walking using symmetry values from side plank endurance test, hip abductor strength test, one-leg standing time tests and walking tests. Study design Cross-sectional study Methods A total of 100 subjects with and without LB & LL pain during walking participated. We measured the side plank endurance time, hip abductor strength and one-leg standing time with eyes open and closed, and the sagittal and frontal head angles at comfortable and fast walking speeds using a wearable wireless earbud sensor and calculated the symmetry index (SI) for each test. Classification and regression tree analysis with 10-fold cross validation was used to develop the classification model. Results The classification tree had 83% accuracy for discriminating people with and without LB & LL pain during walking. The most important factor for classification was the SI of the one-leg standing time with eyes closed; the second-most important factor was the SI of the frontal head angle during fast walking. Conclusions The present classification model can differentiate people with and without LB & LL pain during walking based on symmetry data acquired during functional tests, such as one-leg standing time with the eyes closed and fast walking test using the wearable device. Based on the present results, clinicians can classify patients before and during on- and offline assessments using cutoff values of the SI of the one-leg standing test with eyes closed of 63.88%, and of frontal head motion during a fast-walking test of 63.31%.

국내 서식 흰개미의 개체 및 군체 식별을 위한 Nile Blue A 염색법 적용성 평가

김시현,임익균,정용재 한국문화재보존과학회 2020 보존과학회지 Vol.36 No.5

Dye markers are used in the study of subterranean termites to determine colony territories and population sizes. Dyes not only allow the study of termite biology, but can also be used for control purposes. Although Reticulitermes speratus kyushuensis causes damage to wooden historical properties in Korea, the dye markers have not been applied. Therefore, we evaluated the applicability of Nile Blue A dye for R. s. kyushuensis. Filter papers dyed with concentrations of 0.05%, 0.10%, and 0.25% (w/w) were each fed to termite populations through a no-choice feeding test for 1, 3, or 7 days. After 4 weeks, the survival rate, dyeing rate, and maintenance of dyeing were recorded. The results showed high survival rates with lower dye concentrations and shorter feeding periods. Among the combinations of concentrations and days, high survival rates, dyeing rates, and dyeing maintenance periods were found at concentrations of 0.05% and 0.10% for 3 days of feeding. These maximized the survivorship and visibility. The results from the current study can be applied to investigate the ecology and control of R. s. kyushuensis in both the laboratory and field. 이 연구는 국외에서 지중흰개미의 생태와 방제 연구를 위해 사용하는 Nile Blue A 염색약이 국내 전역에 서식하는 R. s. kyushuensis에 대한 적용 여부 및 적정 조건을 평가하기 위해 수행되었다.

희소 신호 복원을 위한 유전 알고리듬 기반 직교 정합 추구

김시현,Kim, Seehyun 한국정보통신학회 2014 한국정보통신학회논문지 Vol.18 No.9

본 논문에서는 압축적으로 센싱된 희소 신호를 복원하기 위한 유전 알고리듬(GA)에 기반한 직교 정합 추구 방법(GAOMP)을 제안한다. 최근에 제안된 SP, CoSaMP, gOMP 등은 매 반복 단계에서 부적절한 atom을 제거하여 희소 신호의 복원 성능을 개선하였다. 그러나 support set이 국소 최저에 빠져 신호 복원에 실패하는 경우가 발생한다. 제안된 GAOMP는 유전 알고리듬의 중요 연산자인 변이를 통해 support set이 국소 최저를 벗어날 수 있도록 도와주어 희소 신호의 복원 성능을 향상시킨다. 모의 실험을 통해 GAOMP가 여러 OMP 기반 알고리듬과 $l_1$ 최적화보다 우수한 신호 복원 성능을 보임을 알 수 있다. In this paper, an orthogonal matching pursuit (OMP) method combined with genetic algorithm (GA), named GAOMP, is proposed for sparse signal recovery. Some recent greedy algorithms such as SP, CoSaMP, and gOMP improved the reconstruction performance by deleting unsuitable atoms at each iteration. However they still often fail to converge to the solution because the support set could not avoid the local minimum during the iterations. Mutating the candidate support set chosen by the OMP algorithm, GAOMP is able to escape from the local minimum and hence recovers the sparse signal. Experimental results show that GAOMP outperforms several OMP based algorithms and the $l_1$ optimization method in terms of exact reconstruction probability.

Clinical Impact of Cytochrome P450 2C19 Genotype on the Treatment of Invasive Aspergillosis under Routine Therapeutic Drug Monitoring of Voriconazole in a Korean Population

김시현,이동건,권재철,이효진,조성연,박철민,권은영,박선희,최수미,최정현,유진홍 대한감염학회 2013 Infection and Chemotherapy Vol.45 No.4

Background: Genetic polymorphisms of cytochrome P450 enzymes, especially CYP2C19 influence voriconazole pharmacokinetics. However,the impact of CYP2C19 genetic polymorphisms on the therapeutic efficacy and toxicity of voriconazole therapy are not well established. Materials and Methods: In this prospective observational study, we analyzed all consecutive adult patients with hematologic diseaseswho were treated for invasive aspergillosis (IA) with voriconazole between January 2011 and June 2012. CYP2C19 genotype androutine therapeutic drug monitoring of voriconazole were performed. The target range for voriconazole trough levels was 1−5.5 mg/L. Results: A total of 104 consecutive patients were enrolled, including 39 homozygous extensive metabolizers (EMs, 38%), 50 heterozygousextensive metabolizers (HEMs, 48%), and 15 poor metabolizers (PMs, 14%). The initial voriconazole trough levels were 1.8, 2.7, and 3.2mg/L in EMs, HEMs, and PMs, respectively (P = 0.068). Out-of-range initial trough levels were most frequently observed in EMs (46%) followedby HEMs (26%) and PMs (0%) (P = 0.001). The frequency of initial trough levels < 1 mg/L but not > 5.5 mg/L differed significantlyamong the 3 groups (P = 0.005). However, treatment response, all-cause and IA-attributable mortality, and the occurrence of voriconazolerelatedadverse events did not differ significantly among the 3 groups (P = 0.399, P = 0.412, P = 0.317, and P = 0.518, respectively). Conclusions: While none of the initial voriconazole trough levels in PMs was outside the target range, subtherapeutic initialtrough levels were frequent in EMs. Although there was no significant relationship between CYP2C19 genotype and either theclinical outcomes of IA or toxicity of voriconazole, further large-scale multicenter studies using clinical data from homogeneouspopulations are required.