정시안에서 스펙트럼영역 빛간섭단층촬영기를 이용한 연령과 성별에 따른 황반 두께의 변화

김승훈,최경식,이성진,Seung Hoon Kim,Kyung Seek Choi,Sung Jin Lee 대한안과학회 2011 대한안과학회지 Vol.52 No.3

Purpose: To evaluate the changes in macular thickness with regard to age and gender in normal subjects with emmetropia using spectral domain optical coherence tomography. Methods: The present study consisted of 90 healthy subjects (162 eyes) with no ophthalmic evidence of retinopathy and who had emmetropic eyes. The data from macular measurements using spectral domain optical coherence tomography was analyzed according to the groups divided by age (Group 1: 0 to 19 years of age, Group 2: 20 to 39 years of age, Group 3: 40 to 59 years of age, Group 4: 60 to 80 years of age) and gender. Results: Macular thickness of the central circle was 253.40 ± 23.03 μm in all subjects. There was no significant change with age (p > 0.05). However, the measurements at the inner (3 mm) and outer circle (6 mm) showed a reduction of macular thickness with age (p < 0.05). The macular thickness at the central and inner circle was significantly lower in the female subjects (p < 0.05). In group 3 and 4, macular thickness at the central circle in males was greater than in females. In group 3, the average inner macular thickness in males was significantly greater than in females (p < 0.05). Conclusions: In normal subjects with emmetropia, there are statistically significant differences in macular thickness between subjects of different age and gender. The results from the present study can be expected to provide a reference value for evaluating macular disease. J Korean Ophthalmol Soc 2011;52(3):299-307

류마티스 관절염 환자에서 Conserved T 세포 수용체의 CDR3 motif를 표현하는 제2형 콜라겐 특이 T세포주의 형성과 유지

김승훈,조미라,윤지희,박성환,조철수,황수연,김호연,Kim, Seung-Hoon,Cho, Mi-La,Youn, Jeehee,Park, Sung-Hwan,Hwang, Sue-Yun,Cho, Chul-Soo,Kim, Ho-Youn 대한면역학회 2001 Immune Network Vol.1 No.1

Background: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). Methods: We generated CII-specific T-cell lines of 8 RA patients by prolonged in vitro culture with bovine CII (bCII) and the immunogenic peptide (256-270) of human CII. The proliferation response towards CII stimulation was measured from the uptake of 3H-thymidine. Changes in the secretion of Th 1 and Th2 cytokines in the culture supernatent were measured by ELISA. The TCR clonotypes of these T-cells were examined by RT-PCR/SSCP analyses of all 22 $V_{\beta}$ chains. Results: T-cells from patients' tissue exhibited strong proliferation index upon CII stimulation, which was maintained up to 6 months in the culture. The secretion of INF-$\gamma$from these T-cells increased along with the duration of culture time, while the amount of IL-4 production did not show significant changes. The SSCP band patterns of patients' T-cells appear as discrete bands unlike the smeary streak produced from normal samples. Some SSCP bands, each representing selected expansion of a TCR containing certain subtype of $V_{\beta}$ peptides, appeared to be identical in more than one patients. Among these, the expansion of SSCP band representing the $V_{\beta}$ 14 CDR3 region persisted after switching the antigen to the immunogenic human peptide (256-270). Conclusion: CII-reactive T-cells expressing distinct CDR3 motifs are selectively expanded in the peripheral blood and synovial fluid of RA patients, and their persistent proliferation upon CII stimulation, as well as the production Th 1-type cytokines, may play pivotal roles in RA pathogenesis.

복합운동이 비알콜성지방간 비만대학생의 체력과 간염증 인자 및 혈액 변인에 미치는 영향

김승훈(Kim, Seung-Hoon),정현훈(Jung, Hyun-Hun),정민기(Jeong, Min-Ki),박상갑(Park, Sang-Kab) 한국체육과학회 2019 한국체육과학회지 Vol.28 No.3

The purpose of this study was to investigate the effects of aerobic and resistance exercise on physical fitness, liver inflammatory factor and blood variables in obese university students with non-alcoholic fatty liver disease. The results of this study were as follow: In body composition and blood pressure, Body mass index, Lean body mass, % fat were significantly(p<.01) difference time-by-group interactions respectively after 12 weeks in exercise group. In physical fitness, V˙O2max(㎖/min), V˙O2max(㎖/㎏/min), Flexibility, Sit-up(p<.05) were significantly (p<.01) difference time-by-group interactions respectively after 12 weeks in exercise group. In liver inflammatory factor and blood variables, AST(p<.05), ALT(p<.01), TG(p<.05), insulin(p<.05), HOMA-IR(p<.05) and adiponectin(p<.01) were significantly difference time-by-group interactions respectively after 12 weeks in exercise group. These findings suggest that aerobic and resistance exercise may represent an effective intervention strategy for physical fitness and liver inflammatory factor and blood variables.

Pt-Re 이금속 촉매를 이용하여 수소를 생산하는 수성가스 전환 반응에 대한 DFT 연구

김승훈(Seung-hoon Kim),조진원(Jinwon Cho),윤성필(Sung Pil Yoon),한종희(Jonghee Han),이관영(Kwan Young Lee),함형철(Hyung Chul Ham) 한국신재생에너지학회 2018 한국신재생에너지학회 학술대회논문집 Vol.2018 No.4

2019년 자살 관련 지표들과 추이

김승훈 ( Seung Hoon Kim ),이두웅 ( Doo Woong Lee ),권준현 ( Junhyun Kwon ),양지은 ( Jieun Yang ),박은철 ( Eun-cheol Park ),장성인 ( Sung-in Jang ) 한국보건행정학회 2021 보건행정학회지 Vol.31 No.2

This study aimed to update suicide-related indicators including suicidal ideation, suicide attempts, and the number of suicidal deaths. Based on up-to-date information, we observed the trends of suicide-related indicators. In this study, five data sources were used to observe the trends of suicide-related indicators: Statistics Korea (1983-2019), Korean National Health and Nutrition Examination (KNHANES, ‘07-13, ‘15-19), Korean Community Health Survey (KCHS, ‘08-09, ‘13, ‘17), Korean Wealth Panel Study (KOWEPS, ‘12-19), and Korea Health Panel Survey (KHP, ‘10-13, ‘16-17). The suicide rate, which peaked in 2011, declined until 2017 and then started to rise again from 2018, recording a suicide rate of 26.9 per 100,000 people in 2019. The rate of suicidal ideation estimated based on the recently available data was 4.62% (KNHANES, ‘19), 3.51% (KHP, ‘16), 2.87% (KHP, ‘17), and 1.70% (KOWEPS, ‘19). That of suicide attempt as recent year was 0.43% (KNHANES, ‘19), 0.07% (KOWEPS, ‘19). Annual percentage change of death by intentional self-harm was -2.11% (Statistics Korea), and that of suicidal ideation was -14.7% (KNHANES), -2.5% (KCHS), -10.6% (KOWEPS), and -11.3% (KHP). Annual percentage change of suicide attempt was -5.0% (KNHANES), -4.4% (KCHS), and -11.3% (KOWEPS). The lower the income level, the higher the probability of experiencing suicide ideation and suicide attempts. Considering the recent increase in suicide rate in contrast to the continuing decline in suicidal ideation and suicide attempts, continuous data observation and appropriate policies regarding suicide prevention are needed.

환경정보 시스템에 적합한 클러스터 기반 에너지 효율적인 스케줄링 기법

안성현(Sung-Hyun An),김승훈(Seung-Hoon Kim) 한국멀티미디어학회 2008 멀티미디어학회논문지 Vol.11 No.5

타게팅 광고 송출 시스템의 설계와 구현

김종훈(Kim Jong-Hoon),이상규(Lee Sang-Gyu),김승훈(Kim Seung-Hun) 한국방송·미디어공학회 2009 한국방송공학회 학술발표대회 논문집 Vol.2009 No.11

방송 콘텐츠의 소비 경로가 다양화되고 시청 습관이 개인화 되는 추세에 따라 광고주는 그들의 광고가 임의의 대중이 아닌 실제 고객이 될 가능성이 높은 시청자에게 전달되기를 원하며, 그 결과까지 알고 싶어한다. 시청자 개개인에 맞추어 최적의 광고를 선택하기 위해서는 고정된 가입자 정보의 참조에 그치지 않고 송출한 광고를 특정 시청자가 실제 시청하였는지, 추가로 제공되는 양방향 광고에 참여하였는지 여부를 매번 측정하여 스스로 보완되는 구조를 가질 필요가 있다. 본 논문은 이러한 피드백 알고리듬을 기반으로 프로그램 정보와 시청자 정보, 광고의 내용 및 송출 정보를 조합하여 광고주의 의도와 시청자 특성에 맞는 최적의 광고를 송출하는 시스템 구조를 제안한다.

Multiple Pyogenic Abscess of the Hybrid Mice on the Course of Radiation Experiment

이성헌(Sung Heon Lee),신세원(Sei One Shin),김명세(Myung Se Kim),최원희(Won Hee Choi),김승훈(Seung Hoon Kim) 대한방사선종양학회 1985 Radiation Oncology Journal Vol.3 No.2

방사선 치료도중 혹은 치료후의 추적조사에서 이차장염에 의한 염증성 질환 및 방사선에 의해서 야기되는 소견과 합병된 이차 감염 등은 흔히 경험하고 있는 일로서 때로는 이로 인해 치명적일 수 있게 된다. 저자들은 경북지방에서 사육된 정상 잡종쥐를 사용하여 방사선 조사실험을 하던 중 피하조직과 양측 신장부위에 암중으로 생각되는 다발성의 종괴를 발견하여 병리학적 청사를 의뢰하였던 바, 다발성 농양으로 판명되어 말초혈액소견, 소변청사, 대변검사 및 병리학적 소견과 함께 보고하는 바이다. Even though the mechanism and the nature of radiation induced pneumonitis, esophagitis and gastroenteritis were detailed by many authors, complicated secondary infection is still serious problem, sometimes fatal, even today. We experience a case of multiple pyogenic abscess in subcutaneous tissue of the back and both kidneys which could not differenciate from multiple metastatic sarcoma grossly, and report with review of literatures, lab findings.

클라우드 환경에서 대규모 콘텐츠를 위한 효율적인 자원처리 기법

나문성(Moon-Sung Na),김승훈(Seung-Hoon Kim),이재동(Jae-Dong Lee) 한국산업정보학회 2010 한국산업정보학회논문지 Vol.15 No.4

주요 IT 벤더들은 클라우드 컴퓨팅 기술을 이용하여 설치과정 생략, 운용비용 절감, 서비스품질 등에 중점을 두어 대규모 콘텐츠 서비스를 제공하고 있다. 반면에, 대규모 콘텐츠 데이터의 가공, 분석을 수행하는 데이터 처리 프로세스는 처리 시간의 단축을 위한 방법론이 요구되고 있다. 이에 본 논문에서는 클라우드 환경에서 대규모 콘텐츠를 위한 효율적인 자원처리 기법(Efficient_Cloud_Processing_Scheme : ECPS)을 제안한다. 제안한 기법은 리소스 확장 방안을 CPU 및 스토리지 등의 인프라스트럭처 단계에서 설계한다. 대규모 콘텐츠에 대한 자원 할당 방안을 Hadoop 플랫폼 기반의 MapReduce 프로그래밍 기법과 데이터마이닝 분야에서 숨겨진 패턴을 탐지하는데 사용되는 연관규칙을 이용하여 제시한다. 기존 설정값으로 자원을 할당하여 운용 되는 환경과 비교하여 ECPS기법을 적용한 결과, 제안 기법이 20% 이상의 성능 및 속도가 향상되었음을 확인하였다. Major IT vendors expect that cloud computing technology makes it possible to reduce the contents service cycle, speed up application deployment and skip the installation process, reducing operational costs, proactive management etc. However, cloud computing environment for massive content service solutions requires high-performance data processing to reduce the time of data processing and analysis. In this study, Efficient_Cloud_Processing_Scheme(ECPS) is proposed for allocation of resources for massive content services. For high-performance services, optimized resource allocation plan is presented using MapReduce programming techniques and association rules that is used to detect hidden patterns in data mining, based on levels of Hadoop platform(Infrastructure as a service). The proposed ECPS has brought more than 20% improvement in performance and speed compared to the traditional methods.

사용자의 스트레스 완화를 위한 맞춤형 콘텐츠 서비스 시스템의 설계 및 구현

김진성(Jin-Sung Kim),김승훈(Seung-Hoon Kim) 한국콘텐츠학회 2011 한국콘텐츠학회논문지 Vol.11 No.2

사회가 점점 고도화 되면서 스트레스는 중요한 사회적 이슈로 부각되고 있다. 본 논문에서는 스트레스의 완화를 위한 맞춤형 콘텐츠 서비스 시스템을 설계하고 구현한다. 본 제안 시스템에서는 생체신호 및 심리정보를 기반으로 스트레스 증상 및 지수를 계산하고 선호도 등의 사용자 정보를 기반으로 영상, 음향, 향기 및 조명 콘텐츠 조합을 추천하고 추천된 콘텐츠 서비스를 제공한다. 이를 위하여 본 논문에서는 스트레스 증상을 분류하고, 심리정보 측정을 위한 자가평가도구 문항을 정의하였다. 정의된 스트레스 증상에 맞게 영상, 음향, 향기 및 조명 콘텐츠를 분류하였으며, 3단계 사용자 맞춤형 콘텐츠 추천 모델을 제안하였다. 또한 사용자 맞춤형 콘텐츠 서비스 모델을 제안하였으며, 이에 따라 서비스 시스템을 설계 및 구현하였다. 본 시스템은 기존의 시스템들과는 달리 사용자 맞춤형이며 다양한 콘텐츠 조합을 서비스할 수 있는 특징이 있다. As the society has become maturer, stress has emerged as a hot social issue. In this paper, we proposed the design and implementation of a customized contents service system for relieving users' stress. In the proposed system, we compute the stress index from a user's biometics and psychology, and recommend a combination of video, sound, aroma, and lighting based on the index and user's data such as preferences, and provide the recommended contents service. We first classify symptoms of stress and then define a tool for self assessment. We classify video, sound, aroma, and lighting contents as well according to the defined symptoms. We propose 3-phase customized recommender and service model for customized contents service. We design and implement a customized contents service system for relieving users' stress. Different from existing systems, this proposed system has an individually-customized system and provides a diverse combination of different content's types.