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김소영,Kim, So-Yeong 한국낙농육우협회 2016 낙농·육우 Vol.36 No.1
동이 트기도 전, 어둑어둑한 새벽 인천공항으로 향하는 버스에 몸을 실었다. 어린 아들을 두고 떠나는 걱정되는 마음과 꿈에 그리던 나라로 떠난다는 설레는 마음으로 복잡했다. 그런 마음을 아는지 남편은 아무 걱정 없이 다녀오라는 말을 건네며 인사해 주었다. 12시간 긴 비행을 마치고 드디어 네덜란드 땅을 밟는 순간 차가운 바람이 코끝을 스치며 기분이 상쾌했다. 앞으로의 일정이 기대되는 순간이었다.
Influence of Coating Ligands onf Enzyme-linked Immunosorbent Assay of Toluene
김소영,이남택,최명자,Kim, So Yeong,Lee, Nam Taek,Choe, Myeong Ja Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.9
The specificity of conjugation site for coating ligands was investigated using toluene-bovine serum albumin (BSA) conjugates in which BSA was conjugated at the position of o-, m-, and ${\rho}-toluic$ acid. Toluene-BSA conjugated at ${\rho}-position$ showed a binding activity of about 89-95%, whereas, those conjugated at o- and m-position of toluene exhibited a binding activity of 5 and 11%, respectively. On the basis of the above result, coating ligands with various proteins (OVA, BSA, KLH) were compared by conjugating with $\rho-toluic$ acid, and toluene-KLH was considered as the best coating ligand for this ELISA. Indirect competitive ELISA method was developed using anti-toluene antibody and $\rho-position$ conjugated toluene-KLH. The dose-response curve constructed after kinetic and optimization studies showed a 1${\times}$10-4 - 1${\times}$102 mM detectable response range with 0.1 ${\mu}M$ detectability. In specificity test of the antibody, the binding capabilities of aromatic compounds substituted with nitro-, alkyl-, chloro-, and hydroxyl group were larger rather than those of aromatic compounds (benzene, toluene and xylene) themselves. Also, tests with soil and water samples that had been spiked with toluene resulted in 102.7-113.7% recovery.
김소영,김중호,채병윤,Kim, So-Yeong,Kim, Jung-Ho,Chae, Byeong-Yun 대한한방안이비인후피부과학회 1991 한방안이비인후피부과학회지 Vol.4 No.1
In order to verify the effect of Sineungyangjin-Dan on alopecia, I experimented the hair regrowth of the normal mice and of the high butter diet-pretreated mice by feeding each group of mice a certain amount of ethanol extract of Sineungyangjin-Dan and water extract and thus obtained the results as follow; 1. The ethanol extract of Sineungyangjin-Dan was proved to promote the hair regrowth of the hair-removed normal mice. 2. 360mg/kg ethanol extract of Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth by restraining the increase of free cholesterol and triglyceride but by helping the increase of free fatty acid in skin. As a result of the above study Sineungyangjin-Dan was proved to have the effect of promoting hair regrowth.
김소영,Kim, So-Yeong 한국과학기술정보연구원 2006 지식정보인프라 Vol.21 No.-
천문우주, 생명과학과 같은 첨단 R&D에서부터 TV나 김치냉장고 같은 가전제품에 이르기까지 슈퍼컴퓨터의 활용영역이 급속히 확장되고 있다. 그리고 이제 한 나라의 과학기술 수준을 가늠하는 척도로까지 부각되고 있는 슈퍼컴퓨터. 이토록 중요성을 더해가는 슈퍼컴퓨팅의 모든 것을 처음부터 끝까지 이끌고 가다듬고 최적화하는 '슈퍼컴퓨팅의 브레인'들이 바로 KISTI 슈터컴퓨팅사업팀 사람들이다.
고해상도 방사선 영상을 위한 $Gd_2O_3:Eu^{3+}$ 나노 형광체 제조 및 광학적 특성
김소영,강상식,박지군,차병열,최치원,이형원,남상희,Kim, So-Yeong,Kang, Sang-Sik,Park, Ji-Koon,Cha, Byung-Youl,Choe, Chi-Won,Lee, Hyung-Won,Nam, Sang-Hee 대한의용생체공학회 2007 의공학회지 Vol.28 No.1
In this paper, we have synthesized $Gd_2O_3:Eu^{3+}$ nano phosphor particle using a low temperature solution-combustion method. We have investigated the structure and the luminescent characteristic as the sintering temperature and europium concentration. From XRD(X-ray diffraction) and SEM(scanning electron microscope) results, we have verified that the phosphor particle was fabricated a spherical shape with $30{\sim}40nm$ particle size. From the photoluminescence results, the strong peak exhibits at 611 um and the luminescent intensity depends on europium concentration. $Gd_2O_3:Eu$ fine phosphor particle has shown excellent luminescent efficiency at 5 wt% of europium concentration. The phosphors calcinated at $500^{\circ}C$ have possessed the x-ray peaks corresponding to the cubic phase of $Gd_2O_3$. As calcinations temperature increased to $700^{\circ}C$, the new monoclinic phase has identified except cubic patterns. From the luminescent decay time measurements, mean lifetimes were $2.3{\sim}2.6ms$ relatively higher than conventional bulk phosphors. These results indicate that $Gd_2O_3:Eu$ nano phosphor is possible for the operation at the low x-ray dose, therefore, the application as medical imaging detector.
고성능 액체 크로마토그래피를 이용한 Pelubiprofen의 광학분할
김소영 ( Kim So Yeong ),이중기 ( Lee Jung Gi ),서성섭 ( Seo Seong Seob ),박태진 ( Park Tae Jin ),박달근 ( Park Dal Geun ) 한국공업화학회 2003 공업화학 Vol.14 No.6
Pelubiprofen, (±)-(E)-2-[4-(2-Oxo-cyclohexylidenemethyl)-phenyl] propionic acid는 비스테로이드 계열의 진통 및 소염제(NSAID)이다. 이 물질은 골 관절염, 류마티스성 관절염, 근골격성 통증, 수술 후 후유증, 치통 등과 같은 다양한 종류의 질병 치료에 약리활성을 보인다. 본 연구에서는 라세미 pelubiprofen을 HPLC를 이용하여 단일 enantiomer로 분리하기 위한 최적의 조건을 찾기 위한 것이다. 고정상으로는 Kromasil^(ⓡ)CHI-TBB (Eka, chem Sweden) 충진제를 이용하여 4.6×250 mm 크기의 칼럼에 직접 slurry packing을 한 것을 이용하였고, 최적의 이동상의 조성은 hexane/tert-butyl methyl ether/acetic acid의 비가 70/30/0.1 (v/v%)인 것으로 나타났다. 칼럼 효율에 영향을 주는 공정 변수를 조사하였는데 주입농도가 증가함에 따라서 분리도는 4.06에서 3.50으로 감소하였으나 이동상의 유속이 증가함에 따라 주입농도의 증가가 분리도에 미치는 영향은 다소 적은 것을 알 수 있었다. 최적의 분리도를 나타내는 조업조건은 이동상의 유속이 1 mL/min이고 주입부피가 5μL 일 때 4.11로 가장 높은 분리도를 나타내었다. Pelubiprofen, (±)-2-[4-(2-oxocyclohexylidenemethyl)phenyl]propionic acid, is a novel derivative of 2-arylpropionic acid non-steroidal anti-inflammatory drugs (profen NSAIDs). It has a wide variety of indications proposed: osteoarthritis, rheumatoid arthritis, musculoskeletal pain, post-operative trauma, low back pain, scapulohumeral periarthritis, neck-shoulder-arm syndrome and dental pain. In this study, we tried to determine the optimal separation conditions for chiral separation of pelubiprofen using HPLC(High Performance Liquid Chromatography). The Kromasil^(?) CHI-TBB(Eka chem, sweden) was used as a stationary phase and packed in a home-made 46×250 mm column. The mobile phase composition was determined by optimizing the solubility and resolution. It was found to be 70% of hexane, 30% of tert-butyl methyl ether and 0.1% of acetic acid. Process variables effecting column performance were investigated. Resolution decreased from 4.06 to 3.50 with increase of injection eoncentration, but the effect of injection concentration on the resolution was insignificant at higher flow rates. In the our experimental range studied, the highest resolution 4.11 was obtained at the mobile phase flow rate of 1 mL/min with an injection volume of 5 μL.
치과 내원 흡연자의 전자담배 사용 및 사용의도 관련요인
김소영 ( So Yeong Kim ),박종 ( Jong Park ),류소연 ( So Yeon Ryu ),한미아 ( Mi Ah Han ),최성우 ( Seong Woo Choi ) 한국보건정보통계학회(구 한국보건통계학회) 2020 보건정보통계학회지 Vol.45 No.1
Objectives: This study was to investigate the factors affecting the use of electronic cigarettes and intent to use cigarettes who visited dental clinic. Methods: This study is researched 179 people as smoker which visited 2 dental hospital and 3 dental clinic in Gwangju Metropolitan City using questionnaire survey from September 27, 2017 to October 24, 2017. The data was analyzed as frequency, percentage, average, standard deviation, chi-square test, t-test, logistic regression using by SPSS version 24.0 statistics program. Results: Look over the analyze logistic regression using simple analysis result which percentage of relate lower than 0.1 based on answer which electronic cigarettes is no effect as use cessation aid, effective is 5.75 times higher. In case answer the effective as use cessation aid, they relate on use electronic cigarette (95% confidence interval, 95% CI=1.57-21.03). Based on no stress during everyday life, stressed is 3.53 times higher than unstressed and relate on intent to use electronic cigarettes (95% CI=1.25-9.98). Also based on answered no effect as use cessation aid is 6.62 times higher than effective as use cessation aid and related to intent of use electronic cigarette (95% CI=1.58-27.66). Based on doesn’t heard about electronic cigarettes are legally classified cigarettes, heard is 3.31 times higher than doesn’t heard and related on intent of use electronic cigarettes (95% CI=1.26-8.67). Conclusions: In this study, if help to get a correct recognition of electronic cigarettes and use cessation education to use people who visited dental clinic can be possible effective use cessation.