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Antioxidant Effects of Spinach (Spinacia oleracea L.) Supplementation in Hyperlipidemic Rats
고상휘,박재희,김소연,이선우,전순실,박은주 한국식품영양과학회 2014 Preventive Nutrition and Food Science Vol.19 No.1
Increased consumption of fresh vegetables that are high in polyphenols has been associated with a reduced risk of oxidative stress-induced disease. The present study aimed to evaluate the antioxidant effects of spinach in vitro and in vivo in hyperlipidemic rats. For measurement of in vitro antioxidant activity, spinach was subjected to hot water extraction (WE) or ethanol extraction (EE) and examined for total polyphenol content (TPC), oxygen radical absorbance capacity (ORAC), cellular antioxidant activity (CAA), and antigenotoxic activity. The in vivo antioxidant activity of spinach was assessed using blood and liver lipid profiles and antioxidant status in rats fed a high fat-cholesterol diet (HFCD) for 6 weeks. The TPC of WE and EE were shown as 1.5±0.0 and 0.5±0.0 mg GAE/g, respectively. Increasing the concentration of the extracts resulted in increased ORAC value, CAA, and antigenotoxic activity for all extracts tested. HFCD-fed rats displayed hyperlipidemia and increased oxidative stress, as indicated by a significant rise in blood and liver lipid profiles, an increase in plasma conjugated diene concentration, an increase in liver thiobarbituric acid reactive substances (TBARS) level, and a significant decrease in manganese superoxide dismutase (Mn-SOD) activity compared with rats fed normal diet. However, administration of 5% spinach showed a beneficial effect in HFCD rats, as indicated by decreased liver TBARS level and DNA damage in leukocyte and increased plasma conjugated dienes and Mn-SOD activity. Thus, the antioxidant activity of spinach may be an effective way to ameliorate high fat and cholesterol diet-induced oxidative stress.
김연중,김태우,윤종성,김명규 한국해양공학회 2019 韓國海洋工學會誌 Vol.33 No.6
Numerous deaths and substantial property damage have occurred recently due to frequent disasters of the highest intensity according to the abnormal climate, which is caused by various problems, such as global warming, all over the world. Such large-scale disasters have become an international issue and have made people aware of the disasters so they can implement disaster-prevention measures. Extensive information on disaster prevention actively has been announced publicly to support the natural disaster reduction measures throughout the world. In Japan, diverse developmental studies on disaster prevention systems, which support hazard map development and flood control activity, have been conducted vigorously to estimate external forces according to design frequencies as well as expected maximum frequencies from a variety of areas, such as rivers, coasts, and ports based on broad disaster prevention data obtained from several huge disasters. However, the current reduction measures alone are not sufficiently effective due to the change of the paradigms of the current disasters. Therefore, in order to obtain the synergy effect of reduction measures, a study of the establishment of an integrated system is required to improve the various disaster prevention technologies and the current disaster prevention system. In order to develop a similar typhoon search system and establish a disaster prevention infrastructure, in this study, techniques will be developed that can be used to forecast typhoons before they strike by using artificial intelligence (AI) technology and offer primary disaster prevention information according to the direction of the typhoon. The main function of this model is to predict the most similar typhoon among the existing typhoons by utilizing the major typhoon information, such as course, central pressure, and speed, before the typhoon directly impacts South Korea. This model is equipped with a combination of AI and DNN forecasts of typhoons that change from moment to moment in order to efficiently forecast a current typhoon based on similar typhoons in the past. Thus, the result of a similar typhoon search showed that the quality of prediction was higher with the grid size of one degree rather than two degrees in latitude and longitude.
VxWorks 기반의 HAL(Hardware Abstraction Layer) 설계 및 구현
이승훈,이성호,고정호,고상휘,연규옥 한국항공우주학회 2014 한국항공우주학회 학술발표회 논문집 Vol.2014 No.11
VxWorks 운영체제는 실시간성 및 안정성 등의 다양한 이점을 가지고 있으며, 항공 및 국방 분야의 임베디드 시스템에 많이 사용된다. 항공 및 국방 분야에서 사용되는 디바이스는 다양하며, 표준화된 디바이스 드라이버를 VxWorks에서 제공하지 않기 때문에 이에 맞는 디바이스 드라이버를 개발하거나 디바이스 벤더로부터 드라이버를 제공받아 사용해야한다. 이는 OFP(Operational Flight Program)가 디바이스 벤더에서 제공하는 드라이버나 개발한 디바이스 드라이버에 맞추어 변경되어야 한다는 문제를 야기한다. 이에 본 논문에서는 OFP의 재사용성 및 모듈화 특성을 만족시키고, 개발 비용 및 기간을 단축할 수 있는 HAL(Hardware Abstraction Layer) 설계 및 구현 방안을 제시한다. VxWorks has various advantages such as real-time and stability, and it is widely used in embedded systems of the aerospace and defense sector. Because a device that used in the Aerospace and Defense sectors is various and VxWorks is not provide standardized driver, develop the device driver or should be used the driver provided from the device vendor. It causes problems that needs to be changed a OFP(Operational Flight Program) according to the device driver developed and driver provided from device vendor. In this paper, we propose design and implementation method of HAL(Hardware Abstraction Layer) that the reusability and the modularization characteristic of the OFP is satisfied and be able to shorten the development time and costs.