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沙艶華(Sha Yan-Hua),韓相玉(Han Sang-Ok) 조선대학교 지식경영연구원 2006 지역개발연구 Vol.11 No.2
Korean enterprises attempt to enter the China distribution market as a promising future industry. Especially, with the entry into the WTO system, China opened its distribution market to foreign companies, which gave new opportunity for them. In China, distribution industry is in the beginning state but China has a great potentiality in the distribution industry. Not only foreign enterprises but also local enterprises in China expands outsourcing system for the efficiency of distribution service. To meet this trend, Korea must make a promotion plans to the Chinese distribution market as follows : First, Korean distribution enterprises attempting to the China market have prior research for the market. In addition to this, the enterprises should get through knowledge for the market and the area. Second, the enterprises should systematically analyze and understand the legal procedures, legal systems and the market policies relating to the distribution system. Third, to get hegemony in the huge distribution market of China Korean enterprise should strategically expand their scale for competing the global huge enterprises other countries It in also necessary to make systems for the cooperation with the local enterprises of other countries. Fourth, Korean enterprises should set up the differentiated competitive power by using the advanced IT and distribution service. Fifth, Korean goverment build the cooperation systems between Korea and China for setting up the long-term development strategics between them.
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Sha Liao,Shi-Yong Fan,Qin Liu,Chang-Kun L,Jia Chen,Jing-Lai Li,Zhi-Wei Zhang,Zhen-Qing Zhang,Bo-Hua Zhong,Jian-Wei Xie 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.11
Chronic hepatitis B virus (HBV) infection maylead to liver cirrhosis and hepatocellular carcinoma, butfew drugs are available for its treatment. Acyclic nucleosidephosphonates (ANPs) have remarkable antivirusactivities but are not easily absorbed from the gastrointestinaltract and accumulate in the kidneys, resulting innephrotoxicity. Therefore, there is a need to find effectiveliver site-specific prodrugs. The dipivaloyloxymethyl esterof 9-(2-phosphonylmethoxyethyl)adenine (PMEA)—adefovirdipivoxil (ADV)—is a first-line therapy drug forchronic hepatitis B with a low therapeutic index because ofrenal toxicity and low hepatic uptake. In this study, a seriesof PMEA derivatives were synthesized to enhance plasmastability and liver release. The metabolic stability of ADV(Chemical I) and its two analogues (Chemicals II and III)was evaluated in rat plasma and liver homogenate in vitro. An ion-pair reverse-phase HPLC–UV method and a hybridion trap and high-resolution time-of-flight mass spectrometry(LC-IT-TOF-MS) were used to evaluate the degradationrate of the analogues and to identify their intermediatemetabolites, respectively. Chemicals I and II were hydrolyzedby cleavage of the C–O bond to give monoesters. Sufficient enzymatic activation in the liver homogenatethrough a relatively simple metabolic pathway, in additionto a favorable stability profile in rat plasma, made ChemicalII an optimal candidate. Next, six analogues based onthe structure of Chemical II were synthesized and evaluatedin plasma and liver homogenate. Compared toChemical II, these compounds generated less active PMEAlevels in rat liver homogenate. Therefore, chemical modificationof Chemical II may lead to new promising PMEAderivatives with enhanced plasma stability and liveractivation.
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Liu Sha,Cai Yi-xi,Fan Yong-sheng,Li Xiao-hua,Wang Jia-jun 대한환경공학회 2017 Environmental Engineering Research Vol.22 No.1
Direct catalysis of vapors from vacuum pyrolysis of biomass was performed on MCM-41 to investigate the effects of operating parameters including catalyzing temperature, catalyzing bed height and system pressure on the organic yields. Optimization of organic phase yield was further conducted by employing response surface methodology. The statistical analysis showed that operating parameters have significant effects on the organic phase yield. The organic phase yield first increases and then decreases as catalyzing temperature and catalyzing bed height increase, and decreases as system pressure increases. The optimal conditions for the maximum organic phase yield were obtained at catalyzing temperature of 502.7℃, catalyzing bed height of 2.74 cm and system pressure of 6.83 kPa, the organic phase yield amounts to 15.84% which is quite close to the predicted value 16.19%. The H/C, O/C molar ratios (dry basis), density, pH value, kinematic viscosity and high heat value of the organic phase obtained at optimal conditions were 1.287, 0.174, 0.98 g/cm3, 5.12, 5.87 mm2/s and 33.08 MJ/kg, respectively. Organic product compositions were examined using gas chromatography/mass spectrometry and the analysis showed that the content of oxygenated aromatics in organic phase had decreased and hydrocarbons had increased, and the hydrocarbons in organic phase were mainly aliphatic hydrocarbons. Besides, thermo-gravimetric analysis of the MCM-41 zeolite was conducted within air atmosphere and the results showed that when the catalyst continuously works over 100 min, the index of physicochemical properties of bio-oil decreases gradually from 1.15 to 0.45, suggesting that the refined bio-oil significantly deteriorates. Meanwhile, the coke deposition of catalyst increases from 4.97% to 14.81%, which suggests that the catalytic activity significantly decreases till the catalyst completely looses its activity.
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Shang, Jiang-Hua,Xu, Ru-Xiang,Jiang, Xiao-Dan,Zou, Yu-Xi,Qin, Ling-Sha,Cai, Ying-Qian,Yang, Zhi-Jun,Zheng, Xing,Cui, Sheng Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.9
The aim of this study was to evaluate if oocytes, aspirated from postovulatory ovarian follicles of superovulated rabbits 14 h post-hCG administration, could be efficiently used as ooplasm recipients for somatic cell nuclear transfer (SCNT). Within a common SCNT protocol, a comparison between oocytes recovered by direct aspiration (aspirated) from available ovarian follicles and oocytes flushed out from oviducts (flushed) was carried out. The results showed that maturation and enucleation rates of aspirated oocytes were 70.7% and 69.2%, significantly lower than 95.3% (p<0.01) and 83.6% (p<0.05), respectively, from flushed oocytes. However, following enucleation of matured oocytes as ooplasm recipients for SCNT, no difference was recorded in fusion and cleavage rates, as well as blastocyst development from cleaved embryos or hatching of blastocysts between aspirated and flushed groups. Additionally, some matured aspirated and flushed oocytes were also used for immediate parthenogenetic activation and the resulting embryo development was not significantly different. Results from this study show the following: i) the majority of oocytes aspirated from postovulatory ovarian follicles of superovulated rabbits 14 h post-hCG administration are matured and can be used directly as ooplasm recipients for SCNT; ii) the reconstructed embryos derived from these oocytes have similar in vitro developmental ability to those flushed from the oviducts.
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Lin, Jinzhong,Hua, Baozhen,Xu, Zhiping,Li, Sha,Ma, Chengjie Korean Society for Food Science of Animal Resource 2016 한국축산식품학회지 Vol.36 No.4
The aim of this study was to investigate the influence of proteolytic pork hydrolysate (PPH) on yoghurt production by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. Fresh lean pork was cut into pieces and mixed with deionized water and dealt with protease, then the resulting PPH was added to milk to investigate the effects of PPH on yoghurt production. The fermentation time, the viable cell counts, the flavor, free amino acids compounds, and sensory evaluation of yoghurt were evaluated. These results showed that PPH significantly stimulated the growth and acidification of the both bacterial strains. When the content of PPH reached 5% (w/w), the increased acidifying rate occurred, which the fermentation time was one hour less than that of the control, a time saving of up to 20% compared with the control. The viable cell counts, the total free amino acids, and the scores of taste, flavor and overall acceptability in PPH-supplemented yoghurt were higher than the control. Furthermore, the contents of some characteristic flavor compounds including acids, alcohols, aldehydes, ketones and esters were richer than the control. We concluded that the constituents of PPH such as small peptide, vitamins, and minerals together to play the stimulatory roles and result in beneficial effect for the yoghurt starter cultures growth.
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Yong Yao,Li-Hua Ma,Yu-Xiao Liu,Deng-Mu Cheng,Yi Qiu,Li-Sha Wu,Yun Qi 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.5
The thermodynamic properties of small metallic superconducting grains are affected by fluctuations in the order parameter and the level statistics, especially in the critical region. Here, the static path approximation was applied to deal with the fluctuations and the thermodynamic contribution of quasiparticles, and random matrix theory was applied to deal with level statistics. The specific heats were calculated numerically in the cases of even and odd number of electrons and different spins.
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Jinzhong Lin,Baozhen Hua,Zhiping Xu,Sha Li,Chengjie Ma 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.4
The aim of this study was to investigate the influence of proteolytic pork hydrolysate (PPH) on yoghurt production by Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. Fresh lean pork was cut into pieces and mixed with deionized water and dealt with protease, then the resulting PPH was added to milk to investigate the effects of PPH on yoghurt production. The fermentation time, the viable cell counts, the flavor, free amino acids compounds, and sensory evaluation of yoghurt were evaluated. These results showed that PPH significantly stimulated the growth and acidification of the both bacterial strains. When the content of PPH reached 5% (w/w), the increased acidifying rate occurred, which the fermentation time was one hour less than that of the control, a time saving of up to 20% compared with the control. The viable cell counts, the total free amino acids, and the scores of taste, flavor and overall acceptability in PPH-supplemented yoghurt were higher than the control. Furthermore, the contents of some characteristic flavor compounds including acids, alcohols, aldehydes, ketones and esters were richer than the control. We concluded that the constituents of PPH such as small peptide, vitamins, and minerals together to play the stimulatory roles and result in beneficial effect for the yoghurt starter cultures growth.
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( Changcheng Wu ),( Hao Zhang ),( Jiafeng Hua ),( Sha Hua ),( Yanyi Zhang ),( Xiaoming Lu ),( Yichen Tang ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.12
Recognizing license plate from its traffic camera captured images is one of the most important aspects in many traffic management systems. Despite many sophisticated license plate recognition related algorithms available online, license plate recognition is still a hot research issue because license plates in each country all round the world lack of uniform format and their camera captured images are often affected by multiple adverse factors, such as low resolution, poor illumination effects, installation problem etc. A novel method is proposed in this paper to solve the inclination problem of license plates in their camera captured images through four parts: Firstly, special edge pixels of license plate are chosen to represent main information of license plates. Secondly, least square methods are used to compute the inclined angle of license plates. Then, coordinate rotation methods are used to rotate the license plate. At last, bilinear interpolation methods are used to improve the performance of license plate rotation. Several experimental results demonstrated that our proposed method can solve the inclination problem about license plate in visual aspect and can improve the recognition rate when used as the image preprocessing method.
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