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Moby Dick에 나타난 Melville의 자연관과 인간관
한일동,곽승엽 龍仁大學校 1999 용인대학교 논문집 Vol.17 No.-
Throughout his life, Melville experienced inconsistency and disagreements between the ideal and real world. In the mid-l9th century, optimism prevailed under the influence of industrialization. Most people didn't see the dark side of industrialization. There were chasm between rich and poor, differences and absurdities behind that. Most of Melville's works were not estimated appropriately because his thoughts were not accepted by most readers in the mid-l9th century. However, in the 20th century, his works were revaluated by critics who came in harmony with his views. Beth Ahab and Ishmael see the deity's ill-will. But their behaviors are strongly different in their reaction to the evil in the world. Ahab is the accuser of the deity in terms of the deity's apathy and hatred toward man. Ahab fails to fond his image because of his fanatic desire to take retaliation on Moby Dick. He cannot come true his limitations and meets the same fate as his crew. Ishmael, sometimes, accuses the deity but finds also its benevolence, so, Ishmael adapts to reality as it is. He succeeds in finding his image, that is to understand evil as well as good, and man's attitude about nature. Only Ishmael is alive thanks to intuition, adaption and love.
The Effect of Low-dose Ketamine on Post-caesarean Delivery Analgesia after Spinal Anesthesia
( Seung Yeup Han ),( Hee Cheol Jin ),( Woo Dae Yang ),( Joon Ho Lee ),( Seong Hwan Cho ),( Won Seok Chae ),( Jeong Seok Lee ),( Yong Ik Kim ) 대한통증학회 2013 The Korean Journal of Pain Vol.26 No.3
Background: Ketamine, an N-methyl-D-aspartate receptor antagonist, might play a role in postoperative analgesia, but its effect on postoperative pain after caesarean section varies with study design. We investigated whether the preemptive administration of low-dose intravenous ketamine decreases postoperative opioid requirement and postoperative pain in parturients receiving intravenous fentanyl with patient-controlled analgesia (PCA) following caesarean section. Methods: Spinal anesthesia was performed in 40 parturients scheduled for elective caesarean section. Patients in the ketamine group received a 0.5 mg/kg ketamine bolus intravenously followed by 0.25 mg/kg/h continuous infusion during the operation. The control group received the same volume of normal saline. Immediately after surgery, the patients were connected to a PCA device set to deliver 25-μg fentanyl as an intravenous bolus with a 15-min lockout interval and no continuous dose. Postoperative pain was assessed using the cumulative dose of fentanyl and visual analog scale (VAS) scores at 2, 6, 24, and 48 h postoperatively. Results: Significantly less fentanyl was used in the ketamine group 2 h after surgery (P = 0.033), but the difference was not significant at 6, 12, and 24 h postoperatively. No significant differences were observed between the VAS scores of the two groups at 2, 6, 12, and 24 h postoperatively. Conclusions: Intraoperative low-dose ketamine did not have a preemptive analgesic effect and was not effective as an adjuvant to decrease opioid requirement or postoperative pain score in parturients receiving intravenous PCA with fentanyl after caesarean section. (Korean J Pain 2013; 26: 270-276)
The Effect of Low-dose Ketamine on Post-caesarean Delivery Analgesia after Spinal Anesthesia
Han, Seung Yeup,Jin, Hee Cheol,Yang, Woo Dae,Lee, Joon Ho,Cho, Seong Hwan,Chae, Won Seok,Lee, Jeong Seok,Kim, Yong Ik The Korean Pain Society 2013 The Korean Journal of Pain Vol.26 No.3
Background: Ketamine, an N-methyl-D-aspartate receptor antagonist, might play a role in postoperative analgesia, but its effect on postoperative pain after caesarean section varies with study design. We investigated whether the preemptive administration of low-dose intravenous ketamine decreases postoperative opioid requirement and postoperative pain in parturients receiving intravenous fentanyl with patient-controlled analgesia (PCA) following caesarean section. Methods: Spinal anesthesia was performed in 40 parturients scheduled for elective caesarean section. Patients in the ketamine group received a 0.5 mg/kg ketamine bolus intravenously followed by 0.25 mg/kg/h continuous infusion during the operation. The control group received the same volume of normal saline. Immediately after surgery, the patients were connected to a PCA device set to deliver 25-${\mu}g$ fentanyl as an intravenous bolus with a 15-min lockout interval and no continuous dose. Postoperative pain was assessed using the cumulative dose of fentanyl and visual analog scale (VAS) scores at 2, 6, 24, and 48 h postoperatively. Results: Significantly less fentanyl was used in the ketamine group 2 h after surgery (P = 0.033), but the difference was not significant at 6, 12, and 24 h postoperatively. No significant differences were observed between the VAS scores of the two groups at 2, 6, 12, and 24 h postoperatively. Conclusions: Intraoperative low-dose ketamine did not have a preemptive analgesic effect and was not effective as an adjuvant to decrease opioid requirement or postoperative pain score in parturients receiving intravenous PCA with fentanyl after caesarean section.
백서에서 양측 난소절제술이 골밀도 및 IL - 6 치에 미치는 영향
한승엽(Seung Yeup Han),김성한(Sung Han Kim),박근용(Keun Yong Park) 대한내과학회 1997 대한내과학회지 Vol.53 No.3
N/A Objective: Estrogen is a major regulator/modulator of bone metabolism, and bone loss in estrogen deficiency is associated with increased bone turnover, But the mechanism for estrogen action on bone metabolism is still unknown. Recent studies have suggested that the increase in bone loss induced by estrogen deficiency is mediated by increased paracrine production of bone resorbing cytokines. Among cytokines, 1nterleukin-6(IL-6) is released from osteoblasts in estrogen deficiency and increases bone resorption by stimulation of osteoclastic activities and recruitment. Thus we performed this study to evaluate the effect of ovariectomies on bone mineral density and IL-6 in cultured monocytes of peripheral blood and bone marrow. Methods: The experimental animals were 13 female Sprague-Dawley rats that were 8 weeks of age and weighed an average of 188.5 gram at the beginning of the study. Bilateral ovariectomies were performed in all rats from a ventral approach. Bone mineral density(BMD) of the total body, spine and level of IL-6 of cultured monocytes of peripheral blood and bone marrow were measured before and 8 weeks after ovariectomy. Results : 1) BMD of total body and spine were lower after ovariectomy(0.257±0.069g/cm2, 0,208±0.005g/cm2) than before ovariectomy (0.276±0.005g/cm2, 0.229±0.011g/cm2), respectively (P<0.01). 2) Although IL-6 level of cultured monocytes in peripheral blood tended to be higher after ovariectomy than before ovariectomy, this difference was not statistically significant (P>0.05). 3) IL-6 level of cultured monocytes in bone marrow was higher after ovariectomy(82.78±4.99pg/ml) than before ovariectomy(48.85±2.42pg/ml)(P<0.05). Conclusion: It is possible that increased production of IL-6 in estrogen deficiency induced by ovariectomy occurs in the local environment of bone or bone marrow rather than in the pheripheral blood and stimulates bone resorption.
전자현미경 검사상 특징적인 기저막 변화를 나타낸 Nail - Patella 증후군 1 예
한승엽(Seung Yeup Han),강민경(Min Kyoung Kang),황은아(Eun Ah Whang),박성배(Sung Bae Park),김현철(Hyun Chul Kim),전시현(Si Hyun Jeon),강유나(Yu Na Kang),박관규(Kwan Kyu Park) 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5
Nail-patella syndrome is a relatively rare autosomal dominant disorder characterized by dysplastic nail, hypoplastic or absent patella, and dislocation of radial head and iliac horns. In addition, renal abnormalities have been reported. The usual clinical signs of the renal involvement are asymptomatic proteinuria, microscopic hematuria, and in some cases progression to end stage renal disease. We present the case of adult with nail-patella syndrome, who developed proteinuria. Electron microscopy revealed irregular thickening of the glomerular basement membrane with areas of rarefaction, giving rise to a pathognomonic moth-eaten appearance.
시판 지각으로부터 Hesperidin의 분리 및 함량분석
한두일,황방연,황석연,박정일,손건호,이승호,장승엽,강신정,노재섭,이경순 영남대학교 약품개발연구소 2002 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-
Aurantii Fructus has been used in traditional medicine as a digestant, expectorant, and in the treatment of diarrhea, anal prolapse. For the quality control of this crude drug, hesperidin was isolated from the ethylacetate fraction of Citrus aurantium (Rutaceae) and identified by the spectroscopic evidences. A quantitative analysis of hesperidin using HPLC method exhibited that the average contents of hesperidin were 2.13±1.16% in 57 samples collected throughout the various regions of Korea.
CASB의 혼입율 변화에 따른 광물질 혼화재 치환 초고강도 시멘트 페이스트의 특성분석
한천구(Han Cheon-Goo),유승엽(Yoo Seung-Yeup) 대한건축학회 2011 大韓建築學會論文集 : 構造系 Vol.27 No.4
This study Investigates properties of Ultra High Strength Cement Paste using mineral admixtures depending on the contents of CASB. The results are as following. On the flowability corresponding to the contents of CASB, it decreased greatly caused by incease of viscosity on the 5% of CASB. However, it increased slightly over the 5% of CASB because restraint water set free by the improvement of particle size distribution. On the flowability corresponding to the BFS types, it was the biggest BFS Ⅰ when the flow property was relatively big, and BFS Ⅲ was opposite tendency. In these facts, the flowability of Ultra High Strength Concrete related with the improvement of particle size distribution. The compressive strength was high in the case BFS Ⅰ was used and the contents of CASB was increased. it was caused by filling up effect of CASB for capillary void Sized 100 ㎚ and more as SEM and Porosimeter. lf the plasticity and flowability as superplasticizer of CASB were established, it could be a new efficient material for Ultra High Strength Concrete.