Application of Terahertz Spectroscopy and Imaging in the Diagnosis of Prostate Cancer

Zhang, Ping,Zhong, Shuncong,Zhang, Junxi,Ding, Jian,Liu, Zhenxiang,Huang, Yi,Zhou, Ning,Nsengiyumva, Walter,Zhang, Tianfu Optical Society of Korea 2020 Current Optics and Photonics Vol.4 No.1

The feasibility of the application of terahertz electromagnetic waves in the diagnosis of prostate cancer was examined. Four samples of incomplete cancerous prostatic paraffin-embedded tissues were examined using terahertz spectral imaging (TPI) system and the results obtained by comparing the absorption coefficient and refractive index of prostate tumor, normal prostate tissue and smooth muscle from one of the paraffin tissue masses examined were reported. Three hundred and sixty cases of absorption coefficients from one of the paraffin tissues examined were used as raw data to classify these three tissues using the Principal Component Analysis (PCA) and Least Squares Support Vector Machine (LS-SVM). An excellent classification with an accuracy of 92.22% in the prediction set was achieved. Using the distribution information of THz reflection signal intensity from sample surface and absorption coefficient of the sample, an attempt was made to use the TPI system to identify the boundaries of the different tissues involved (prostate tumors, normal and smooth muscles). The location of three identified regions in the terahertz images (frequency domain slice absorption coefficient imaging, 1.2 THz) were compared with those obtained from the histopathologic examination. The tissue tumor region had a distinctively visible color and could well be distinguished from other tissue regions in terahertz images. Results indicate that a THz spectroscopy imaging system can be efficiently used in conjunction with the proposed advanced computer-based mathematical analysis method to identify tumor regions in the paraffin tissue mass of prostate cancer.

Surface-functionalized Hexagonal Mesoporous Silica Supported 5-(4-Carboxyphenyl)-10,15,20-triphenyl Porphyrin Manganese(III) Chloride and Their Catalytic Activity

Zhang, Wei-Jie,Jiang, Ping-Ping,Zhang, Ping-Bo,Zheng, Jia-Wei,Li, Haiyang Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.12

Manganese(III) 5-(4-carboxyphenyl)-10,15,20-triphenyl porphyrin chloride (Mn(TCPP)Cl) was grafted through amide bond on silica zeolite Y (HY), zeolite beta ($H{\beta}$) and hexagonal mesoporous silica (HMS). XRD, ICP-AES, $N_2$ physisorption, SEM, TEM, FTIR and thermal analysis were employed to analyse these novel heterogeneous materials. These silica supported catalysts were shown to be used for epoxidation and good shape selectivity was observed. The effect of support structure on catalytic performance was also discussed. The catalytic activity remained when the catalysts were recycled five times. The energy changes about epoxidation of alkenes by $NaIO_4$ and $H_2O_2$ were also computationally calculated to explain the different catalytic efficiency.

Application of Terahertz Spectroscopy and Imaging in the Diagnosis of Prostate Cancer

Ping Zhang,Shuncong Zhong,Junxi Zhang,Jian Ding,Zhenxiang Liu,Yi Huang,Ning Zhou,Walter Nsengiyumva,Tianfu Zhang 한국광학회 2020 Current Optics and Photonics Vol.4 No.1

The feasibility of the application of terahertz electromagnetic waves in the diagnosis of prostate cancer was examined. Four samples of incomplete cancerous prostatic paraffin-embedded tissues were examined using terahertz spectral imaging (TPI) system and the results obtained by comparing the absorption coefficient and refractive index of prostate tumor, normal prostate tissue and smooth muscle from one of the paraffin tissue masses examined were reported. Three hundred and sixty cases of absorption coefficients from one of the paraffin tissues examined were used as raw data to classify these three tissues using the Principal Component Analysis (PCA) and Least Squares Support Vector Machine (LS-SVM). An excellent classification with an accuracy of 92.22% in the prediction set was achieved. Using the distribution information of THz reflection signal intensity from sample surface and absorption coefficient of the sample, an attempt was made to use the TPI system to identify the boundaries of the different tissues involved (prostate tumors, normal and smooth muscles). The location of three identified regions in the terahertz images (frequency domain slice absorption coefficient imaging, 1.2 THz) were compared with those obtained from the histopathologic examination. The tissue tumor region had a distinctively visible color and could well be distinguished from other tissue regions in terahertz images. Results indicate that a THz spectroscopy imaging system can be efficiently used in conjunction with the proposed advanced computer-based mathematical analysis method to identify tumor regions in the paraffin tissue mass of prostate cancer.

Testing Investigation of Protective Coatings for Downhole Oil Tube

( Li Ping Zhang ),( Qi Bin Zhang ),( Yan Jun Zhang ),( Bei Bei Xie ),( Ying Ying Zhang ) 한국부식방식학회(구 한국부식학회) 2008 Corrosion Science and Technology Vol.7 No.1

Which Indicator Among Lumbar Vertebral Hounsfield Unit, Vertebral Bone Quality, or Dual-Energy X-Ray Absorptiometry-Measured Bone Mineral Density Is More Efficacious in Predicting Thoracolumbar Fragility Fractures?

Bo Zhang,Lu-Ping Zhou,Xian-Liang Zhang,Dui Li,Jia-Qi Wang,Chong-Yu Jia,Hua-Qing Zhang,Liang Kang,Ren-Jie Zhang,Cai-Liang Shen 대한척추신경외과학회 2023 Neurospine Vol.20 No.4

Objective: Hounsfield units (HU), vertebral bone quality (VBQ), and bone mineral density (BMD) can all serve as predictive indicators for thoracolumbar fragility fractures. This study aims to explore which indicator provides better risk prediction for thoracolumbar fragility fractures. Methods: Patients who have received medical attention from The First Affiliated Hospital of Anhui Medical University for thoracolumbar fragility fractures were selected. A total of 78 patients with thoracolumbar fragility fractures were included in the study. To establish a control group, 78 patients with degenerative spinal diseases were matched to the fracture group on the basis of gender, age, and body mass index. The lumbar vertebral HU, the VBQ, and the BMD were obtained for all the 156 patients through computed tomography, magnetic resonance imaging, and dual-energy x-ray absorptiometry (DEXA). The correlations among these parameters were analyzed. The area under curve (AUC) analysis was employed to assess the predictive efficacy and thresholds of lumbar vertebral HU, VBQ, and BMD in relation to the risk of thoracolumbar fragility fractures. Results: Among the cohort of 156 patients, lumbar vertebral HU exhibited a positive correlation with BMD (p < 0.01). Conversely, VBQ showed a negative correlation with HU, BMD (p < 0.05). HU and BMD displayed a favorable predictive efficacy for thoracolumbar fragility fractures (p < 0.01), with HU (AUC = 0.863) showcasing the highest predictive efficacy, followed by the DEXA-measured BMD (AUC = 0.813). VBQ (AUC = 0.602) ranked lowest among the 3 indicators. The thresholds for predicting thoracolumbar fragility fractures were as follows: HU (88),VBQ (3.37), and BMD (0.81). Conclusion: All 3 of these indicators, HU, VBQ, and BMD, can predict thoracolumbar fragility fractures. Notably, lumbar vertebral HU exhibits the highest predictive efficacy, followed by the BMD obtained through DEXA scanning, with VBQ demonstrating the lowest predictive efficacy.

A Single Chord Localization Algorithm for Wireless Sensor Networks

Yong-Luo Shen,Yuan Zhang,Yu-Ping Hu,Jun Zhang 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.1

This paper presents a novel range-free single chord localization algorithm with low energy consumption and high accuracy for wireless sensor networks. A mobile anchor node and a mobile reference node are employed to periodically broadcast beacon messages and reference messages, respectively. Each sensor node is equipped with a received signal strength indicator for comparing the signal strength. By using the edge function and the result of comparing signal strength, each sensor node only needs one chord on the communication circle for localization. Compared with previous approaches that require multiple chords, less beacon messages are required by the sensor nodes. In the proposed algorithm, the localization error mainly depends on the move distance interval. However, for the other approaches, large localization errors can be observed according to the angle between chords which may descend the localization accuracy dramatically. Analysis results indicate that the proposed algorithm is superior to other approaches in energy consumption and localization accuracy.

Performance bounds for relative configuration and global transformation in cooperative localization

Ping Zhang,Jian Lu,Qiao Wang 한국통신학회 2016 ICT Express Vol.2 No.1

Cooperative localization introduces internode measurements to provide the node relative locations instead of absolute locations. This paper decomposes the absolute locations into relative configuration and global transformation, where the former can be specified by the internode measurements while the latter requires reference information. This decomposition can be used to investigate the relative localization which uses only internode measurements and the absolute localization with the consideration of anchor location uncertainty. After deriving the coordinate representations, error metric, and performance bounds for the global transformation, we evaluate the performance of a node location calibration that uses the measurements from sources in unknown locations.

Line-Interactive UPS for Low-Voltage Microgrids

Ping Zhang,Huanyu Cai,Hengyang Zhao,Jianjiang Shi,Xiangning He 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.6

Line-interactive uninterruptible power supply (UPS) systems are good candidates for providing energy storage within a microgrid. In this paper, a control scheme for a line-interactive UPS system applied in a low-voltage microgrid is presented. It is based on the Q-w and P-E droop control to achieve a seamless transition between grid-connected and stand-alone operation modes. Moreover, a new model for designing the controllers is built in the dq-frame based on the instantaneous power definition. The new-built model takes into account the dynamic performance of the output impedance of the inverter in the dq-frame and can be evaluated in the time domain. Compared to the traditional model based on the instantaneous power definition, the new-built model is more accurate to describe the dynamic performance of the system. Simulation and experimental results obtained with a microgrid consisting of two 40-kW line-interactive UPS systems are given to validate the control strategy of the line-active UPS system and the accuracy of the new-built model.

Phosphino-polycarboxylic acid modified inhibitor nanomaterial for oilfield scale control: Synthesis, characterization and migration

Ping Zhang,Dong Shen,Gedeng Ruan,Amy T. Kan,Mason B. Tomson 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.45 No.-

A facile synthesis approach is reported to prepare scale inhibitor nanomaterial for oilfield scale control. The presence of a polymeric scale inhibitor can considerably change the morphology of the nanomaterialwith a reduced particle size and an enhanced particle stability. In addition, the presence of electrolyte andsonication methods can impact the morphology and stability of the nanomaterial as well. Laboratorytransport experiments suggest that the inhibitor nanomaterial has the future potential for oilfieldmineral scale control. This is thefirst report of the synthesis and characterization of a template-free scaleinhibitor nanomaterial combining both phosphonate and polymeric scale inhibitors.

Cooperative localization in 5G networks: A survey

Ping Zhang,Jian Lu,Yan Wang,Qiao Wang 한국통신학회 2017 ICT Express Vol.3 No.1

In upcoming 5G networks, key prospects such as increased bandwidth, smaller cells, higher mobile terminal (MT) densities, multiple radio access technologies, and the capability of device-to-device communication are beneficial for localization. Meanwhile, technologies suggested in 5G, such as massive multiple-in multiple-out, would also benefit from the accurate locations of MTs. Therefore, an opportunity to develop and integrate mobile localization technology in 5G networks has presented itself at this early stage. This paper reviews recent literature relating to localization in 5G networks, and emphasizes the prospect for implementing cooperative localization, which exploits the location information from additional measurements between MTs. To evaluate the accuracy of cooperative localization, a performance evaluation approach is also suggested.