응급실에 내원한 약물중독환자의 지역별 비교분석

임근우,박일영,유승진,나병호,오동렬,전해명,황주일,김세경 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

We reviewed retrospectively 230 patients who came to emergency room of Kang Nam St. Mary's Hospital and Uijongbu St. Mary's Hospital between 1. January and 31. December 1994. We classified them according to their age, sex, a sort of drug, the cause of poisoning, prehospital care, time-lapse to arrive at hospital after poisoning, psychiatric problem the status of patients. *We conclude as follows; 1. The male to female ratio was totally 1 : 1.98, 1 : 1.24 in a urban area, 1 : 2.43 in a rural area. 2. On age of the patients in this study, the peake incidence was between 20 and 39(55.2%). 3. On seasonal prevalence, the poisoning was most common in summer and spring, in urban area(35.7%) and rural area(37.0%) respectively. 4. The common drug were as follow; Doxylamine, Organophosphate, Acetaminophen in urban area, Paraquat, Organophospate, Doxylamine in rural area 5. The percentage of suicidal attempt were 81.8% and 87.7% in urban area and rural area respectively. 6. The poisoning patients had psychatric problem in 19.4% and 24.6%, in urban area and rural area respectively. 7. Before arrival to emergency room, 27.7% of patient was done prehospital care in rural area. 8. On arrival to emergency room, 95.1% and 73.8% of patients show stable vital sign in urban area and rural area respectively.

工業團地內 새마을運動 共同推進方案에 관한 硏究

金千鎰,裵源達,林德相,張晩植 효성여자대학교 새마을연구소 1989 새마을硏究論文集 Vol.9 No.-

효율적 인력물자 운반용 적·하화대의 개발 및 활용

황춘수,장통일,임현교 한국안전학회 2003 한국안전학회지 Vol.18 No.2

In recent years, the Korean Army made use of fork-lifters or conveyors when loading and/or unloading military material in order to prevent accidents and to promote efficiency of military material handling activities. However, in troops smaller than battalions, manual material handling activities are still committed for many reasons. In this thesis, a brand new loading/unloading device for efficient military material handling for manual workers was developed, and its validation study was conducted through objective assessment based on electromyography, subjective assessment based on Body-Map technique developed by Corlett and Bishop, and finally work performance comparison. The results of EMG analysis showed that muscular workload improved by 24% when using the device compared to manual work without the device, and complain of each body part was remarkably reduced. In addition, remarkable effectiveness enhancement was observed in the work performance. Consequently, it could be concluded that ergonomic devices like one developed in this research should he studied further in the ergonomic sense as well as in the economical sense.

한국인의 급성 골수성 백혈병 및 골수 이형성 증후군과 HLA 연관성

윤정숙,김원일,한경자,김용구,임지향,민우성,김춘추 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.1

배경:주조직 적합항원 복합체(Major Histocompatibility Complex : MHC)는 쥐에서 처음 이식 항원으로 발견된 이래 이식 면역 분야에서 광범위하게 연구되어 왔으며, 면역 반응을 조절하는 주요 유전자로서 감염, 종양, 자가면역 질환 등의 발생에 관여한다. 사람에서 자가 면역 질환과 HLA 연관성이 증명되어 있으나, 백혈병에서 HLA 연관성에 관한 연구는 드물며 대상군 수가 유의한 결론을 얻기에 부족하다. 본 연구에서는 급성 골수성 백혈병(AML)과 골수 이형성 증후군(MDS) 환자를 대상으로 HLA class I, II 항원 및 2-유전자좌 일배체형 빈도를 구하고, 이를 정상 대조군과 비교하는 통계적 방법으로 AML 및 MDS군과 연관된 HLA 항원 및 일배체형이 있는지 살펴보고, AML군은 FAB 분류와 면역 표현형 분류에 따른 아군으로 분류하여 각 아군과 연관된 HLA 항원 및 일배체형을 관찰함으로써 AML 및 MDS군과 HLA의 연관성을 규명해 보고자 하였다. 방법:1991년 1월부터 1998년 7월까지 성모병원에 내원하여 NIH standard microlymphocytotoxicity를 이용한 혈청학적 방법으로 HLA class I, II 항원 형별 검사를 실시한 415례의 AML과 62례의 MDS 환자를 대상으로 하여 각 질환군과 FAB, 면역 표현형 아군에서 HLA 항원 빈도와 유전자 빈도를 구하고, 항원 빈도를 대조군과 비교하여 Haldane’s method에 따라 상대 위험도(RR)를 구한 뒤 chi-square 법으로 유의성을 검증하였다. AML, MDS 각 질환군과 아군에서 square root법을 이용하여 HLA A-B, C-B, B-DR 2-유전자좌 일배체형 빈도를 구하고, 이를 대조군과 비교하여 chi-square 법으로 유의성을 검증하였다. 결과:1) Cw8이 AML, MDS 질환군에서 RR이 0.10, 0.22로 매우 감소하여 이들 질환과 강한 연관성 정도를 나타냈다(p<0.001). 2) Blank 유전자 빈도의 증가가 AML, MDS 질환군의 각 HLA locus에서 관찰되었으며, 특히 이 분석 결과는 DR locus에서 현저하여, AML과 MDS군에서 DR-blank 빈도는 11.6%, 7.0%로 매우 증가하였다. 3)AML군과 A2-B61, Cw8-B61, B62-DR11 일배체형 연관성과, MDS군과 Cw3-B51, B62-DR14, B35-DR9 일배체형 연관성이 관찰되었다. 4)FAB 분류별 아군에서 AML-M3와 A33 항원 연관성과 AML-M1과 A2-B51 일배체형 연관성이 높은 통계적 유의성을 나타내었다(p<0.001). 5) AML 면역 표현형 아군에서 HLA-A29, B56 항원과 panmyeloid 면역 표현형인 CD33, CD15와의 연관성이 관찰되었고, A2-B48, Cw7-B44 일배체형과 myeloid 면역 표현형인 CD34, CD33, CD11c와의 연관성이 관찰되었다. 결론:AML과 MDS는 HLA와 연관성 있는 질환이며, AML과 MDS군의 발생 및 AML군에서 백혈병 세포의 분화 단계를 예측하기 위해 본 연구 자료가 유용할 것으로 생각된다. Background:The Major Histocompatibility Complex (MHC) has been widely studied in the field of transplantation immunology, since initially defined as transplantation antigen in mouse in 1936. Although associations have been demonstrated between many autoimmune diseases and HLA in human, the studies of HLA association with human leukemia are rare, and have too small sample size to get a significant result. We tried to invesgate the association of AML and MDS with HLA, and the association of FAB, immunological subgroup with HLA in AML group by using appropriate statistical methods. The purpose of this study is to elucidate the HLA role in the development of AML and MDS, and find any HLA antigens or haplotypes which can predict the development of AML or MDS. Methods: The subject of this study was 415 patients with AML and 62 patients with MDS who admitted in St. Mary's hospital between 1991. 1. and 1998. 7., and were typed for HLA class I, II antigens by using serological method of NIH standard microlymphocytotoxicity. We calculated the HLA antigen, gene and 2-locus haplotype frequencies in AML and MDS group and FAB, immunological subgroup, calculated relative risk by Haldane's method by comparing HLA antigen frequencies in disease group with those in normal control population. The Chi-Square method or Fisher's exact test was used to assess the significance of the differencies in the antigen and haplogtype distributions in the control vs disease population. Results: 1)The frequencies of Cw8 were severely decreased in AML and MDS population with relative risk of 0.10, 0.22, and revealed high statistical significance with p-values less than 0.001, suggesting strong Cw8 association with AML and MDS. This means Cw8 may be a gene which resists to the development of AML and MDS, or may be linked to other recessive gene, Cw8 may be a gene which encodes increased immune responses to exogenous antigens such as leukemia virus, or may be linked to other immune response gene, otherwise, Cw8 may be an antigen which has a key role in immune surveillance to the development of AML or MDS. 2) Blank gene frequencies were increased in AML and MDS group, and this phenomenon was prominent in DR locus, showing 11.6% and 7.0% of DR-blank gene frequencies in AML and MDS. This suggests increased HLA homozygosity or increased undetected antigens due to loss or modification of HLA alleles in AML and MDS. 3) The associations of A2-B61, Cw8-B61, B62-DR11 haplotypes with AML, and A30-B14, Cw3-B51, B62-DR14, B35-DR9 haplotypes with MDS were observed. 4) According to FAB classification in AML, highly significant HLA-A33 antigen association with AML-M3 and A2-B51 haplotype association with AML-M1 were observed. 5) According to immunological classification in AML, HLA-A29, B56 each antigen association with CD33, CD15, panmyeloid immunophenotypes and A2-B48, Cw7-B44 each haplotype association with CD34, CD33, CD11c, myeloid immunophenotypes were observed. Conclusion:AML and MDS is a disease associated with HLA, and this study will be valuable in predicting the development of AML and MDS, differentiation stages of leukemic cells in AML.

An Early Maturing, High Quality, and High Yielding Rice Cultivar "Sangmibyeo"

Kil Lim Ryu,Jung Kon Kim,You Chun Song,Jeong IL Kim,Sang Jong Lim,Soon Chul Kim,Moo Sang Lim,Hee Woo Lee,Yeon Kyu Hong,Dae Sik Kim 한국육종학회 2003 한국육종학회지 Vol.35 No.1

Sangmibyeo' is a japonica rice cultivar developed from a cross between Sambaegbyeo and Ou 316 by Sangju Substation of National Yeongnam Agricultural Experiment Station, R.D.A. in 1998. The cultivar is early maturing with heading date of August 7 in ordina

An Early-Maturing, High-Quality, and High-Yielding Rice Cultivar "Munjangbyeo"

Kil Lim Ryu,Jeong IL Kim,You Chun Song,Jung Kon Kim,Beong Chul Moon,Sang Jong Lim,Ho Yeong Kim,Hae Chune Choi,Soon Chul Kim,Moo Sang Lim,Hee Woo Lee,Yeon Kyu Hong,Dae Sik Kim 한국육종학회 2003 한국육종학회지 Vol.35 No.1

Munjangbyeo' is a japonica rice cultivar developed from a cross between Sangsanbyeo and Suweon 397 by Sangju Substation of National Yeongnam Agricultural Experiment Station, RDA in 1999. The cultivar is early matured with heading date of Aug. 2 in ordinar

면역효소항체법에 의한 B - 용혈성 연쇄구균 Streptococcus sp. 의 신속진단에 대하여

전세규,박수일,최동림 한국어병학회 1988 한국어병학회지 Vol.1 No.2

양식어류의 세균성 질병의 신속한 진단을 위하여 틸라피아(O. niloticus)로부터 분리된 β용혈성 연쇄구균인 Streptococcus sp. KST-2균주를 사용하여 면역효소법으로 검출실험을 하였으며, 면역효소법의 현장사용의 용이함과 검출의 민감도를 알아보기 위하여 counterimmunoelectrophoresis(CIE), 및 이중면역확산법등과 비교하여 보았다. 다른 어류 병원균과의 교차반응 결과 교차반응이 전혀 일어나지 않는 것으로 보아 이 방법은 β용혈성 연쇄구균(KST-2균주)에 매우 특이적임을 알 수 있었다. 연쇄구균의 검출실험한 결과 면역효소법은 1×10³CFU/㎖의 농도까지 검출가능하였으며, 검출의 민감성이 CIE에 비해 10²배, 이중면역확산법에 비해 10⁴배나 높은 것으로 나타났다. 면역효소법은 이번 연구에서 사용된 진단법 중에서 현장사용이 가장 용이하며, 민감성이 가장 뛰어난 것으로 나타났다. For the rapid diagnosis of bacterial diseases of cultured fishes, the immunoperoxidase method was applied to the detection of β-haemolitic Streptococcus sp. strain KST-2 isolated from tilapia(Oreochromis niloticus). The suitability- of field analysis and the sensitivity of the immunoperoxidase method was compared with those of the counterimmunoelectrophoresis (CIE) and the immunodiffusion(ID). Results of testing cross-reactivity which did not indicate any cross reactivity with other fish pathogens, this method was specific to Streptococcus sp. The sensitivity of this method was 1×10³CFU/㎖ which was at least 10²times greater than the CIE and 10⁴times greater than the ID. The immunoperoxidase method was more suitable for field application and more sensitive than other diagnostic techniques tested on this study.

Channel Training for MIMO Relay Systems in the Presence of Interference

Chun, Chang-Jae,Kim, Il-Min,Lim, Dong-Woo,Kim, Hyung-Myung IEEE 2017 IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY Vol.66 No.11

<P>In this paper, we propose an optimal channel training method in the sense of linear minimum mean square error for multiple-input multiple-output amplify-and-forward relay systems in the presence of interference. By using a relay processing matrix, the received interference is cancelled or mitigated. To make the problem tractable, we first derive the optimal structure of the training signal and the relay processing matrix. Then, we propose an optimal channel training method. In order to reduce the complexity, we also propose an asymptotically optimal channel training method. Simulation results demonstrate that the two proposed methods outperform the conventional training signal design methods in terms of both the mean square error and in the bit error rate.</P>

Stimulative and Sedative Effects of Essential Oils upon Inhalation in Mice

Lim, Won-Churl,Seo, Jeong-Min,Lee, Chun-Il,Pyo, Hyeong-Bae,Lee, Bum-Chun The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.7

This study investigated the stimulative or sedative effects of inhaling fragrant essential oils (EOs) by using a forced swimming test (FST) with mice. This behavioral test is commonly used to measure the effects of antidepressant drugs. The inhalation by mice of EOs, such as ginger oil (p<0.05), thyme oil (p<0.05), peppermint oil (p<0.05), and cypress oil (p<0.01) resulted in 5% to 22% reduction of immobility. The same results were achieved when over-agitation was artificially induced in the mice by an intraperitoneal injection of caffeine (a psycho-stimulant). In contrast, inhalation of some EOs by the mice resulted in increased immobility. To evaluate more correctly the sedative effects of EOs, the immobility of over-agitated mice induced with caffeine was ascertained after the inhalation of various EOs. Inhalation of lavender oil (p<0.01) and hyssop oil (p<0.01) increased the immobile state in mice that were treated with caffeine. The results of this study indicate that the inhalation of essential oils may induce stimulative or sedative effects in mice.

Poster Session : NO/ROS in Cell Signaling ; Anti-inflammatory effects of the synthetic militarins

( Chun Hoi Kim ),( Young Chul Lim ),( Ho Gyoung Kim ),( Mi Hee Lim ),( Min Kyong Kim ),( Hae Il Park ),( Ki Chul Hwang ),( Jae Mo Sung ),( Tae Woong Kim ) 한국생화학분자생물학회 (구 한국생화학회) 2007 생화학분자생물학회 춘계학술발표논문집 Vol.2007 No.-