페나진 유도체들의 抗菌性에 관한 분자궤도론적 연구

郭庚度,朴柄珏,金鎬順,徐萬哲,金鐘大 嶺南大學校附設 基礎科學硏究所 1988 基礎科學硏究 Vol.8 No.-

The electronic states of the antimicrobial phenzine and its derivatives were examined by Extended H?uckel Method. It was found that the sum of nucleophilic reactivity index for trans 1,2, and 4 positions, ?? in a molecule was found to be related antimicrobial activity. The index, ??, should be applied to biological activity as well as antimicrobial activity.

민어(Miichthys miiuy)의 卵發生過程 및 仔稚魚 발육단계에 따른 형태발달

한경호,오성현,황동식,조영현,서대철 한국어류학회 2002 韓國魚類學會誌 Vol.14 No.2

본 연구는 2000년 8월 19일 전라남도 신안군 임자도 연안에서 2각망으로 어획된 민어 어미를 인위적인 방법으로 수정하여 부화 사육하면서 관찰한 卵發生 過程 및 仔稚魚 형태변화는 다음과 같다. 1. 민어의 受精卵은 구형의 분리 부성난으로 알의 크기는 0.96~1.08㎜(평균 1.01㎜, n=50)였고, 크고 작은 油球가 1~5개(0.06~0.34㎜) 존재하였다. 2. 사육수온 25.2~28.4℃에서 受精 후 17시간 10분에는 배체가 卵膜을 뚫고 머리부터 孵化하기 시작하였다. 3. 孵化 직후 仔魚의 전장은 2.36~2.63㎜(평균 2.48㎜, n=10)로 전장의 45.0~47.0%에 달하는 큰 卵黃(장경 1.11~1.20㎜, 단경 0.92~0.96㎜)을 가지고 있으며 筋節은 7~8+ 17~19=24~27개였다. 4. 孵化 후 3일째 仔魚는 전장 3.98~4.32㎜(평균 4.16㎜, n=10)로 입은 열려있었고, 이 시기에 섭이활동이 활발하게 관찰되면서 卵黃이 완전히 흡수되어 後期仔魚期로 이행되었다. 5. 孵化 후 10일째 後期仔魚는 전장이 5.88~6.74㎜(평균 6.30㎜, n=10)로 꼬리의 말단이 굽어지기 시작하는 시기로 黑色素胞가 기저후두골 뒷부분의 체측에서 점모양 및 나뭇가지모양 으로 출현하였다. 6. 孵化 후 31일째 개체의 전장은 9.62~12.76㎜(평균 11.12㎜, n=10)로 모든 지느러미가 정수에 달하였고, 체형이나 반문이 成魚와 닮아 種魚期로 이행하였다. Egg development and morphological change of larvae of the brown croaker, Miichthys miiuy, were investigated after obtaining samples by artificial insemination. The spawning season extends from the middle to the end of August in the seas off Lim-ja Island, Cheollanam-do. The fertilized eggs were transparent, spherical, separate and they floated. Egg diameter ranged 0.96~1.08㎜ with several oil globules of 0.06~0.34㎜. Hatching occurred 17 hours 10 minutes after fertilization in 25.2~28.4℃ water temperature. The newly-hatched larvae were 2.36~2.63㎜(mean:2.48㎜, n=10) in total length(TL), had a large yolk, and 7~8+17~19=24~27 myotomes. Melanophores were distributed on the eye lens. Three days after hatching the larvae had attained 3.98~4.32㎜ in TL(mean:4.16㎜, n=10), the yolk sac was completely absorbed, and they had transformed into the postlarva stage. The larva reached the juvenile stage with all fins formed and with a complete set of fin rays(D.Ⅹ-28~31;A.Ⅱ-7~8;P. 21~23;C. 19~21;V. 25~26) on the 31st day after hatching. The juveniles were 9.62~12.76㎜(mean:11.12㎜, n=10) in total length. At this point the juvenile was similar to the adult in body form and pigmentation pattern.

工團 周邊 農耕地 土壤의 成分 變化에 관한 硏究

鄭大守,金度勳,金賢勍 東亞大學校 1995 東亞論叢 Vol.32 No.-

溫山工業團地 造成에 따른 土壤汚染의 정도를 調査하기 위하여 1988年부터 1994年까지 7년간에 걸쳐 工團 隣近地域의 논과 밭 土壤에 대한 土壤成分의 理化學的인 變化를 調査分析한 結果를 要約하면 다음과 같다. 土壤의 pH 變化는 논과 밭 土壤 모두 每年 pH가 약간씩 減少하여 土壤 酸性化가 深化되어지고 있으며, 一部 地域에서는 pH 5.0 以下의 强酸性을 나타내는 곳도 있었다. 논 土壤의 特性變化에서는 有機物含量과 有效燐酸의 含量은 全國平均보다 낮았으며, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向이었다. 밭 土壤의 特性變化에서도 有機物含量과 有效燐酸의 含量은 全國平均보다 낮게 나타났으며, K이온은 全體 平均이 0.85me/100g으로 全國平均 0.5m3/100g보다도 높은 含量을 보였고, Ca++이온과 Mg++이온의 含量은 每年 增加하는 傾向을 나타내었다. A study was carried out to investigate the possibility of soil pollution in Onsan Industrial Complex. Physical and chemical properties of soil were analyzed. Soil samples were collected from paddy and upland soil around the Onsan Industrial Complex between 1988 and 1994. The results were summarized up as follows: Soil acidity of paddy and upland soil was slightly decreased every year respectively. Some sampling area and showed the strong acidity which was less than pH 5.0. For the characteristics of paddy soil, the content organic matter and phosphroic acid were lower than that of Korean average. The content of Mg ++ and Ca++ were increased by degree every year. In the case of upland, the content of organic matter and phosphoric acid showed similar pattern as low as Korean average. The content of K+ was higher as the value of 0.85me/100g comparing with the Korean average, 0.5me/100g. For the Mg++ and Ca++, the contents were also increased by degree every year, respectively.

인삼사포닌의 마우스 비장 임파구에 대한 면역활성

정경수,이대우,양희정,이순철,김길현 충남대학교 약학대학 의약품개발연구소 1994 藥學論文集 Vol.10 No.-

To ellucidate immunologic activities of ginseng saponin, the splenic leukocytes of BALB/c mice were incubated in RPMI medium for 48hr with or without ginseng total saponin(GTS), and then analyzed flow cytometrically. Upto the concentration of 100㎍/㎖, GTS exherted stimulatory effect on the immune cells most prominently on B cells: the percentage of the surface Immunoglobulin (sIg) -positive cells (B cells) of the control was 47.l%, while that of GTS treated was 58.9%. The percentages of monoclonal antibody(mAb) J1j-reactive cells (T cells) were 28.8% and 3l.3%, those of mAb Gkl.5-reactive cells (CD4' T cells) were l8.5% and l9.l%, and those of mAb M1/70-reactive cells (mostly macrophages) were 4.4 and 5.0% at the concentration of 0 and 100㎍/㎖, respectively. However, at the concentration of 300㎍/㎖ or higher, GTS was found to be toxic to the immune cells especially to B cells in that the flow rate of the cells (gated viable cells) significantly decreased and the percentage of B cells droped from 58.9% to 31.2% and 25.4% at l00, 300, and 1000㎍/㎖, respectivelly. These data strongly suggests that GTS would exhert B-cell mitogen-like activity at physiological concentrations of 100㎍/㎖ or lower.

참나무류의 용도개발을 위한 비교내후성 연구 : Tyromyces palustris와 Coriojus versiclolor균을 중심으로 By Tyromyces Palustris and Coriolus Versicolor

정대교,민경희 건국대학교 교육대학원 1990 敎育論叢 Vol.13 No.-

This study was carried out to investigate the relative durability of 6 Quercus species. The relative durability of decay was expressed by the percentage of weight loss. The test fungi were Tyromyces palustris and Coriolus versicolor. The results are as follows: 1.Heart wood of Q. dentata and sap wood of Q. variabilis were showed the highest durability for T. palustris and the lowest decay-resistance was heart and sap wood of Q. mongolica for it. 2.For C. versicolor, the durability of heart and sap wood of Q. dentata highest and it of Q. mongolica was showed the lowest without any difference heart wood and sap wood. 3.The weight loss were not showed the significant difference among the samples taken from different height of the tree for all 6 species. The weight loss of all 6 species, however, were significant above 450cm of the trunk expect sapwood of Q, dentata and Q. variabilis for T. palustris. 4.Quercus dentata may be the best decay-resistant by T. palustris and C. versicolor for T. palustris.

窒素, 燐酸 및 加里의 施肥水準이 藥用作物 仙鶴草(Agrimonia pilosa L.)의 生育 및 收量에 미치는 影響

김현경,황필성,이용호,김기영,정대수 東亞大學校 大學院 2000 大學院論文集 Vol.25 No.-

This study was carried out to determine the effect of various fertilizer levels on the growth and yield of Agrimony. this experiment was conducted for 2years from 1998 to 1999 in Medicinal Plant Experiment Station, Kyungnam ARES. The results obtainned were summarized as follows : 1. The growth characteristics such as plant height, tillers and leaf numbers were more increased at 22-10-10 plot than of other fertilizer levels. 2. Variations of percent flowering of Agrimonia pilosa L. treated with different fertilizer levels were more increased at 22-10-10 plot than of other fertilizer levels. 3. Yield per 10a of Agrimonia pilosa L., Fresh weight was 1,500kg in 22-10-10 plot, and 243kg in non-treatment plot. The dry weight was 736kg in 22-10-10 plot, and 96kg in non-treatment plot. Yield of Seed and Fruit following to different application levels was highest at the fertilizing plot of N, P2O5, K2O=22-10-10.

비글개에서 신우황청심원의 급성 및 아급성독성시험

권오경,성하정,곽형일,방명주,신대희,이진영,박대규,정규혁,윤효인,조명행 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

Single and 4 weeks oral administration of New Woohwangchungsimwon (NWCH) which was used l-muscone as substitutive material of musk, to beagle dogs of both sexes were performed to investigate both acute and subacute toxicity. Beagle dogs(3 males and 3 females) in acute experiments were administered orally with single dose of 2,000 ㎎/㎏ and groups of 9 male and 9 female beagle dogs in subacute experiments were given daily different dosage of NWCH, 160 ㎎/㎏/day(low dosage group), 400 ㎎/㎏/day (middle dosage group), 1,000 ㎎/㎏/day (high dosage group) once a day for 4 weeks by oral route according to the Established Regulation of Korea Food and Drug Administration (1996. 4. 16). LD_50 value for beagle dogs was more than 2,000 ㎎/㎏ per oral for both male and females. In animals administered with NWCH, there were neither dead animals nor significant changes of body weights. In addition, no differences were found between control and treated groups in clinical sign, urinalysis, eye examination, hematology, serum chemistry, organ weight and other fingings. No histological lesions were observed in both control and treatment groups. Above data strongly suggset that NWCH in beagle dogs is considered to be safe.

참깨 種實의 發芽중 脂肪酸 組成의 變化에 관한 硏究

鄭大守,金度勳,丁海鎭,金賢勍 東亞大學校生命資源科學大學附設 農業資源硏究所 1995 農業生命資援硏究 Vol.4 No.1

참깨 種子를 25℃의 incubator에서 10日 동안 發芽시키면서, 發芽後 1日, 3日, 5日, 10日로 區分하여 試料를 採取하여 油脂含量과 脂肪酸組成의 變化를 比較 分析한 結果는 참깨 種子 發芽中 油脂含量의 變化는 發芽前 안산깨가 53.8%, 단백깨가 52.5% 發芽後 5日에 18.8%와 13.6%, 10日째에 9.3%와 7.3%로 減少하였다. 그리고 總脂質中의 脂肪酸 組成은 幼植物이 成長함에 따라 palmitic acid, stearic acid 및 linolenic acid는 增加하였으나, linoleic acid는 減少하는 傾向을 나타내었고, 發芽後 5日과 10日의 子葉部와 胚軸部의 脂肪酸 組成은 linolenic acid는 急激히 增加하였으나, palmitic acid, stearic acid 및 oleic acid 減少하는 傾向을 나타내었다. Sesame(Sesamum indicum L.) seeds were germinated at 25℃ for 10 days in order to investigate changes in the oil contents and fatty acid composition of total lipid. The sample for analysis was distinguished with 1st day, 3rd day, 5th day and 10th day after germination. In Ansan and Danbak varieties during the germination period, the oil contents were decreased continuously from 53.8%, 52.5% pre-germination 18.8%, 13.6% on the 5th day, and 9.3%, 7.3% on the 10th day after germination. In fatty acid composition of total lipids, palmitic acid, stearic and linolenic acid were increased, but linoleic acid showed the opposite tendency, according to the growth of seedling. In fatty acid composition of cotyledon and seedling axis, linolenic acid was increased rapidly, but palmitic acid, stearic acid and oleic acid decreasing trends showed during the germination periods.

근대적 인간관에 기원한 정치사회 성격에의 재고찰 : 마키아벨리, 홉스, 로크, 루소를 중심으로

권경주,윤대식 建陽大學校 1997 建陽論叢 Vol.- No.5

Contemporary man is at the beginning of postmodernity in historical process. We must understand postmodernity and our ontological status based on the modernity. Therefore understanding and accepting of postmodern elements are limited in the present based on mosernity. Considering discourses on the human nature and political society provided by modern political thinkers who had the vision on new order and prosperity, we can understand our situation confronted with new order and have opportunities seeking some proposals to prepare.

목초액의 엽면살포가 선학초(Agrimonia pilosa L.)의 종자수량에 미치는 영향

정대수,신상현,김현경,오주성,이용호 東亞大學校 大學院 2002 大學院論文集 Vol.27 No.-

Agrimonia pilosa L. has been used as a medicinal plant in traditional folk remedy, and it shows inereasing tendency at various sections such as medicine-making material, functional food, and agricultural chemicals using plant or extract. The treatment was 400times solution(50㎖), 600times solution(33.3㎖), 800times solution(25㎖), 1,000times solution(20㎖) and 1,200times solution(16.7㎖) level with foliar application of wood extraction in Agrimonia pilosa L. The results obtained through these experiments were summarized as follows; plant height, stem number, leaves was increased with 800times solution(25㎖) foliar application of wood extraction. Among foliar application of wood vinergar soution diluted by 800-1,200 times was most effective considering growth and yield as compared other dilutions and control plot.