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이광희,추영란 대구보건대학 1994 대구보건대학 論文集 Vol.14 No.-
A study was presented of the masurement of protein in fermented milk with the Folin reagent and with coomassie brilliant blue G 250. Inoculated skim milk was estimated in pH and protein concentration each 3hrs. Protein concentrations by lowry method were shownd various change and by braford method lower gradually. It seems that the protein concentration in fremented milk are influenced strongly by protease activity. The adventage of braford method is the simplicity and rapidity, but coomassie blue do not react with free amino acid and very small peptide.
A Case of Optic Neuropathy Treated by Percutaneous Trans-coronary Angiography
Young Kwang Chu,Helen Lew,Sang Yeul Lee 대한안과학회 1999 Korean Journal of Ophthalmology Vol.13 No.2
There are many risk factors involved in the development of ischemic optic neuropathy such as diabetes mellitus, hypertension, arteriosclerosis, and vascular incompetence. Therefore, the treatment of ischemic optic neuropathy should not be solely based on proper diagnosis but should also involve a thorough and systemic investigation to identify those multifactorial possibilities, which may contribute to the pathogenesis of the disease. We report upon a patient who developed non-arteritic ischemic optic neuropathy following treatment of a sphenoethmoid mucocele, which lead to recovered vision and a satisfactory improvement of visual field defects, after percutaneous trans-coronary angiography with stent insertion of the coronary arteries.
Surgical treatment modalities of thyroid ophthalmopathy
Young Kwang Chu,Sung Joo Kim,Sang Yeul Lee 대한안과학회 2001 Korean Journal of Ophthalmology Vol.15 No.2
This report presents the use of various surgical treatment modalities in patients who were diagnosed as having thyroid ophthalmopathy. The records of 53 patients who received surgery because of thyroid ophthalmopathy at the Department of Ophthalmology, Yonsei University College of Medicine between Sept. 1996 and Jan. 2000 were retrospectively evaluated. Among the 53 patients, there were 30 females and 23 males. The mean ages of the patients were 40.8 ± 17.1 years. Orbital wall decompression (52.8%) was the most frequently performed surgery followed by lid surgery (49.1%) and strabismus surgery (26.4%). Only one type of surgery was performed on 86.8% of the patients while 13.2% received more than one type of surgery. Among the many different types of surgeries possible in patients that have thyroid ophthalmopathy, orbital wall decompression, lid surgery, and strabismus surgery are the most commonly used surgical methods for treatment.
Chu, Young Kwang,Hong, Young Taek,Byeon, Suk Ho,Kwon, Oh Woong by Ophthalmic Communications Society, Inc. 2013 Retina Vol.33 No.10
PURPOSE:: To describe characteristic findings of acute retinal ischemic damage in optical coherence tomography. METHODS:: Eighteen cases of acute retinal arterial occlusion with available fundus photography, optical coherence tomography, and/or fluorescein angiography in the early phase (<1 month) with more than 2 months follow-up were reviewed. A site-to-site analysis between optical coherence tomography morphology and correlating fundus images were done on each visit. RESULTS:: Retinal opacities at first presentation were vague to mild opacity in four eyes, moderate (affecting visibility of underlying choroidal vessels) in seven, severe (yellow to whitish) in five, and very severe (chalky white) in two. These changes eventually disappear within 1 month (8 of 9 eyes). Inner retinal hyperreflectivity and a “prominent middle limiting membrane” in optical coherence tomography were consistently noticed up to 1 month showing regional correlation with the retinal opaque areas and was readily identified even in areas with vague or disappeared retinal opacities. Later, inner retinal atrophic changes replace these ischemic optical coherence tomography signs. CONCLUSION:: A prominent middle limiting membrane sign is a useful indicator of acute ischemic retinal damage, especially in cases showing subtle or resolved retinal opacities before the onset of atrophic changes.
신약 개발을 위한 참당귀(Angelica gigas Nakai) 추출 Decursin과 Decursinol Angelate의 약리 작용
손추영(Chu-Young Son),송규용(Gyu-Yong Song),강재선(Kwang-Il Kwon),권광일(Kwang-Il Kwon),백인환(In-Hwan Baek) 대한약학회 2009 약학회지 Vol.53 No.6
Traditionally, Cham dang-gui (Angelica gigas Nakai) is one of the most popular herbal medicines in Asian countries including Korea. A. gigas has been used as a functional food product for treatment anemia, women’s health care, a sedative, an anodyne or a tonic agent. Decursin and decursinol angelate isolated from the roots of A. gigas are pyranocoumarin compounds. Recently, as the global herbal medication market is increasing, investigations about pharmacological effects of decursin and decursinol angelate are rapidly increasing. We summarized previous studies about pharmacological effects of decursin and decursinol angelate, and reviewed relation with pharmacological effects of decursin and decursinol angelate on human disorder, focused on the approach for new drug development. Pharmacological effects of decursin and decursinol angelate were classified as anti-tumor activity, anti-bacterial activity, improvements of the circulating system, inhibition of cytochrome P-450 activity, anti-inflammation activity, anti-oxidant activity and cognitive-enhancing activites. The activity of A. gigas with improvement of the circulating system may have wide therapeutic potential for circulatory diseases, including diabetes, hyperlipidemia and atherosclerosis. Also, anti-inflammation ctivity A. gigas may be beneficial for the treatment and prevention of asthma, atopic dermatitis and rheumatism arthritis. This relation could potentially lead to the development of herbal new drugs. In order to development a new drug containing decursin and decursinol angelate, it is also necessary to consider the safety profile, and the information in this review would contribute to development a new drug from herbal medicine.
Park, Chu Hong,Jang, Gwan,Seon, Dong Young,Sun, In Young,Ahn, Chi Hyun,Ryu, Ho-young,Lee, Sang Heon,Kim, Kwang Myeong Korean Society of Pediatric Nephrology 2017 Childhood kidney diseases Vol.21 No.2
Purpose: To evaluate changes in quality of life (QoL) in patients with neurogenic bladder treated with clean intermittent catheterization (CIC), who changed from a multiple use catheter (MUC) to single use catheter (SUC). Methods: The Modified Intermittent Self-Catheterization Questionnaire (mISC-Q) was used to determine potential changes in patients' QoL as a result of switching from MUC to SUC. The mISC-Q consists of questions within four categories: ease of use, convenience, discreetness, and symptomatic benefit. Answers were graded as Strongly agree (+2), Agree (+1), Not sure (0), Disagree (-1), and Strongly disagree (-2). Overall patient QoL, as well as by sex, disease (presence of augmentation cystoplasty), and catheterization route (via urethra or urinary diversion), were analyzed. Results: Thirty-eight patients (21M:17F; mean age: $21.7{\pm}5.3y$) submitted questionnaires. For ease of use, SUC was significantly better than MUC (score: 0.364, P=0.002) in all patients. Patients with catheterization via the urethra showed significant favor for SUC in ease of use (score: 0.512, P<0.001) and convenience (score: 0.714, P=0.011), but patients with catheterization via the abdominal stoma of urinary diversion gave negative scores in all categories, though no categories were significant. Conclusion: This study suggested that changing from MUC to SUC may lead to improvements in QoL, especially regarding ease of use. This benefit was clearly found in patients with catheterization via urethra rather than abdominal stoma of urinary diversion.
황-요오드 열화학 수소체조 공정에서 2 액상 정체 특성
이광진(Lee, Kwang-Jin),차광서(Cha, Kwang-Seo),강영한(Kang, Young-Han),박주식(Park, Chu-Sik),배기광(Bae, Ki-Kwang),김영호(Kim, Young-Ho) 한국신재생에너지학회 2007 한국신재생에너지학회 학술대회논문집 Vol.2007 No.06
The objective of this work was to study the properties of purification of two liquid phase for exclusion of impurities in each phase. The experiments for process variables were carried out in the temperature range(H_{2}SO_{4} phase: 413{sim}513 K, HI_{x} phase: 353{sim}453 K) and in the N_{2} flow rate range(H_{2}SO_{4}, HI_{x} phase: 50{sim}200 mL/min). As the results, it is appeared that the principles of H_{2}SO_{4} phase purification was due to stripping, evaporation and reverse bunsen reaction and HI_{x} phase purification was due to stripping and reverse bunsen reaction. In purification of H_{2}SO_{4} phase, the concentration rate of H_{2}SO_{4} phase was controled by temperature but the temperature had few effects on yield of H_{2}SO_{4}. In purification of HI_{x} phase, we observed products of side reactions(H_{2}S, S) over 433 K. The purity of HI_{x} phase was increased with increasing N_{2} flow rate because impurites were decreased with increasing conversion of reverse reaction.