기내 닥터콜과 환자의 안전

임소연(So Yun Lim),박소정(So Jung Park),전유경(Yookyung Jeon),조향기(Hyang Ki Cho),임주원(Juwon Lim) 한국항공우주의학협회 2017 항공우주의학회지 Vol.27 No.2

EMR 시계열에서 최근 건강상태 영역 탐색

이유경(YooKyung Lee),임명은(MyungEun Lim),최재훈(JaeHun Choi) 한국정보과학회 2021 한국정보과학회 학술발표논문집 Vol.2021 No.12

2단 도립진자의 Stable Periodic Orbits 제어

오유경(Yookyung Oh),이종범(Jongbeom Lee),임창석(Changseok Lim),이영삼(Young Sam Lee) 대한전기학회 2023 정보 및 제어 심포지엄 논문집 Vol.2023 No.10

음성압축 방식의 변화가 한국어 단음절 숫자 인지기능에 미치는 영향의 비교 연구

임덕환,원유경,Lim, Dukhwan,Won, Yookyung 한국음향학회 2013 韓國音響學會誌 Vol.32 No.3

다양한 음성 압축방식이 여러 분야에서 광범위하게 사용되고 있으며 그 심리음향적 인지결과는 대상 언어의 특성과 압축 방식에 따라서 다를 수가 있다. 한국어에서도 이러한 인지 결과를 비교하는 정량적인 자료가 관련된 임상이나 응용 분야에서 필요하지만 구체적인 내용이 확인되어 있지 않다. 본 연구에서는 통제된 언어적 특성을 갖는 0에서 9까지 한국어 단음절 숫자 들이 무작위로 조합되는 다섯 쌍 조합(quintet set)을 대상으로 하여 자주 사용되는 세가지 대표적인 음성 압축방식의 특성을 비교 분석하였다. 비교 기준으로는 기존의 연구에서 분석 정리된 시간과 주파수 정보가 모두 일정하게 변화되는 PNT (Preserving No Trait) 압축에서 얻은 자료를 비교 근거로 선정하였다. 이를 기준으로 하여 동일한 조건의 정상인 그룹에서 심리음향적 피치(pitch) 정보가 주로 보전되는 PPT (Preserving Pitch Trait), 시간 정보가 주로 보전되는 PTT (Preserving Time Trait) 압축방식의 인지 결과를 기록하고 분석하였다(N=20). 본 연구 결과에서 얻어진 자료를 보면, 정보의 압축비율이 높을 수록 심리음향학적으로 중요한 주파수 정보(피치)를 보전하는 것이 인지도 측면에서 가장 유리한 것으로 나타났다(PPT>PTT>PNT). 또한, 세가지 압축방법에서 50% 인지율을 보이는 압축률의 역치도 PPT가 20%, PTT가 42%, PNT가 44% 순으로 나타났다. 따라서 인지도 측면에서만 살펴보면 본 조건에서는 PPT 압축 방식이 가장 우수한 것으로 추정되었다. 이러한 숫자 자극을 이용한 평가 방법은 향후 새로운 압축 방식의 효율성과 인지도 측면을 비교 가능하게 하며, 이를 이용하면, 청각정보처리기능을 진단하거나 압축 관련 특수 보청기 적합 재활에서 정량적인 지표를 제공하는 도구로도 사용될 수 있을 것으로 판단된다. The performances of speech compression schemes appeared to be dependent on the response profiles to compressed stimuli and the features of individual languages to some extent. Although these response profiles were critical in comparing various compression outcomes, the related data were limited in number for Korean monosyllabic words. From the previous study, data from PNT (Preserving No Trait) compression was selected as a base set for comparison. In this study, the outcomes from PPT (Preserving Pitch Trait) and PTT (Preserving Time Trait) were analyzed under the same condition. Then, the properties of these three widely used representative compression schemes were quantitatively compared in normal hearing adults (N=20) for controlled Korean quintet digit sets (0 through 9). Results showed that PPT compression scheme exhibited the best perceptual performances for the Korean quintet digit sets in the final outcomes (PPT>PTT>PNT). The compression ratios of 50% performances were estimated as about 20%, 42%, and 44% for PPT, PTT, and PNT, respectively. The data indicated the influences of the salient psychoacoustic features of the three representative compressions on perceiving Korean monosyllabic digit words. This controlled procedure with monosyllabic quintet sets can evaluate efficiency and effectiveness of other compression schemes and may also contribute to diagnosing auditory processing disorders and fitting special hearing aids with compression issues.

Cytokinin signaling promotes root secondary growth and bud formation in Panax ginseng

Kyoung Rok Geem,Yookyung Lim,Jeongeui Hong,Wonsil Bae,Jinsu Lee,Soeun Han,Jinsu Gil,Hyunwoo Cho,Hojin Ryu The Korean Society of Ginseng 2024 Journal of Ginseng Research Vol.48 No.2

Background: Panax ginseng, one of the valuable perennial medicinal plants, stores numerous pharmacological substrates in its storage roots. Given its perennial growth habit, organ regeneration occurs each year, and cambium stem cell activity is necessary for secondary growth and storage root formation. Cytokinin (CK) is a phytohormone involved in the maintenance of meristematic cells for the development of storage organs; however, its physiological role in storage-root secondary growth remains unknown. Methods: Exogenous CK was repeatedly applied to P. ginseng, and morphological and histological changes were observed. RNA-seq analysis was used to elucidate the transcriptional network of CK that regulates P. ginseng growth and development. The HISTIDINE KINASE 3 (PgHK3) and RESPONSE REGULATOR 2 (PgRR2) genes were cloned in P. ginseng and functionally analyzed in Arabidopsis as a two-component system involved in CK signaling. Results: Phenotypic and histological analyses showed that CK increased cambium activity and dormant axillary bud formation in P. ginseng, thus promoting storage-root secondary growth and bud formation. The evolutionarily conserved two-component signaling pathways in P. ginseng were sufficient to restore CK signaling in the Arabidopsis ahk2/3 double mutant and rescue its growth defects. Finally, RNA-seq analysis of CK-treated P. ginseng roots revealed that plant-type cell wall biogenesis-related genes are tightly connected with mitotic cell division, cytokinesis, and auxin signaling to regulate CK-mediated P. ginseng development. Conclusion: Overall, we identified the CK signaling-related two-component systems and their physiological role in P. ginseng. This scientific information has the potential to significantly improve the field-cultivation and biotechnology-based breeding of ginseng.

A Magnetic Resonance-based Seed Localization Method for I-125 Prostate Implants

Lee, Rena J.,Suh, HyunSuk,Lee, Kyung-Ja,Lim, Soome,Kim, Yookyung,Kim, Sungkyu,Choi, Jinho KOREAN ACADEMY OF MEDICAL SCIENCE 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22//SUP No.-

<P>This study was performed to develop and evaluate a semi-automatic seed localization algorithm from magnetic resonance (MR) images for interstitial prostate brachytherapy. The computerized tomography (CT) and MR images (3 mm-slice thickness) of six patients who had received real-time MR imaging-guided interstitial prostate brachytherapy were obtained. An automatic seed localization method was performed on CT images to obtain seed coordinates, and an algorithm for seed localization from MR images of the prostate was developed and tested. The resultant seed distributions from MR images were then compared to CT-derived distribution by matching the same seeds and calculating percent volume receiving 100% of the prescribed dose and the extent of the volume in 3-dimensions. The semiautomatic seed localization method made it possible to extract more than 90% of the seeds with either less than 8% of noises or 3% of missing seeds. The mean volume difference obtained from CT and MR receiving 100% of the prescribed dose was less than 3%. The maximum extent of the volume receiving the prescribed dose were 0.3, 0.6, and 0.2 cm in x, y, and z directions, respectively. These results indicate that the algorithm is very useful in identifying seeds from MR image for post-implant dosimety.</P>

A Magnetic Resonance-based Seed Localization Method for I-125Prostate Implants

HyunSuk Suh,Rena J. Lee,Kyung-Ja Lee,Soome Lim,Yookyung Kim,김성규,Jinho Choi 대한의학회 2007 Journal of Korean medical science Vol.22 No.S

This study was performed to develop and evaluate a semi-automatic seed localization algorithm from magnetic resonance (MR) images for interstitial prostate brachytherapy. The computerized tomography (CT) and MR images (3 mm-slice thickness) of six patients who had received real-time MR imaging-guided interstitial prostate brachytherapy were obtained. An automatic seed localization method was performed on CT images to obtain seed coordinates, and an algorithm for seed localization from MR images of the prostate was developed and tested. The resultant seed distributions from MR images were then compared to CT-derived distribution by matching the same seeds and calculating percent volume receiving 100% of the prescribed dose and the extent of the volume in 3-dimensions. The semiautomatic seed localization method made it possible to extract more than 90% of the seeds with either less than 8% of noises or 3% of missing seeds. The mean volume difference obtained from CT and MR receiving 100% of the prescribed dose was less than 3%. The maximum extent of the volume receiving the prescribed dose were 0.3, 0.6, and 0.2 cm in x, y, and z directions, respectively. These results indicate that the algorithm is very useful in identifying seeds from MR image for post-implant dosimety.