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Yong-Wun Cho,Woong-Sun Yoo,Inyoung Chung,Seong-Wook Seo,Ji-Myong Yoo,Seong-Jae Kim 대한안과학회 2016 Korean Journal of Ophthalmology Vol.30 No.2
Purpose: To compare the two transscleral fixation (TSF) techniques of intrascleral pocket and conventional scleral flap with conjunctival division techniques in terms of short-term clinical effects. Methods: This retrospective cohort study included all consecutive patients with aphakia in Gyeongsang National University Hospital in Jinju, Korea, who underwent TSF between January 2012 and December 2014. The medical records of all patients were retrospectively reviewed, and the endothelial cell count (ECC), refraction, best-corrected visual acuity (BCVA), intraocular pressure, slit lamp, and fundus examination results before and 1 day and 6 months after surgery were recorded. The postoperative complications and visual outcomes were also recorded. Results: The intrascleral pocket and conventional-flap groups did not differ significantly in terms of demographics, presurgical BCVA, or ECC. However, the intrascleral pocket group had a significantly lower BCVA at 1 day and 6 months after surgery compared to the conventional-flap group. The two groups did not differ in terms of ECC 6 months after surgery. The intrascleral pocket group had no postoperative complications, but five patients in the conventional-flap group complained of irritation. In both groups, the intraocular lens was well positioned without tilting or subluxation, and astigmatism was significantly reduced at 1 day and 6 months after surgery. Conclusions: The intrascleral pocket technique of TSF does not involve conjunctival dissection and is a successful method of sulcus fixation. It stably corrects the intraocular lens and is easy to perform, which helps to reduce operation time. It also reliably yields rapid visual acuity recovery without complications.
3-D Laser Measurement using Mode Image Segmentation Method
Hak-Yong Moon,Jong-Chan Park,Wun-Dong Han,Heung-Gi Cho,Hee-Jong Jeon 전력전자학회 2001 ICPE(ISPE)논문집 Vol.2001 No.10
In this paper, the 3-D measurement method of moving object with a laser and one camera system for image processing method is presented.<br/> The method of segmentation image in conventional method, the error are generated by the threshold values.<br/> In this paper, to improve these problem for segmentation image, the calculation of weighting factor using brightness distribution by histogram of stored images are proposed.<br/> Therefore the image erosion and spread are improved, the correct and reliable informations can be measured.<br/> In this paper, the system of 3-D extracting information using the proposed algorithm can be applied to manufactory automation, building automation, security guard system, and detecting information system for all of the industry areas.
Removal of Iopromide and Its Intermediates from Ozone-Treated Water Using Granular Activated Carbon
Ahn, Yong-Tae,Cho, Dong-Wan,Kabra, Akhil N.,Ji, Min-Kyu,Yoon, Yeojoon,Choi, Jaewon,Choi, Il-Hwan,Kang, Joon-Wun,Kim, Jung Rae,Jeon, Byong-Hun Springer-Verlag 2015 Water, Air and Soil Pollution Vol.226 No.10
Lee, Yong Jae,Lee, Jung-Yun,Cho, Min-Soo,Nam, Eun Ji,Kim, Sang Wun,Kim, Sunghoon,Kim, Young Tae Asian Society of Gynecologic Oncology; Korean Soci 2019 Journal of Gynecologic Oncology Vol.30 No.1
<P><B>Objectives</B></P><P>We conducted a protocol-based cohort study to evaluate the outcomes of interval debulking surgery (IDS) followed by paclitaxel-based hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of advanced-stage ovarian cancer.</P><P><B>Methods</B></P><P>From October 2015 to May 2018, 65 patients with stages IIIC–IV ovarian cancer were treated according to the study protocol. HIPEC was performed with paclitaxel (175 mg/m<SUP>2</SUP>) for 90 minutes, only in cases of optimal cytoreduction.</P><P><B>Results</B></P><P>Of 65 patients, 40 (61.5%) patients underwent neoadjuvant chemotherapy (NAC), 34 (52.3%) patients had a high tumor burden with a Fagotti score ≥8 at diagnostic laparoscopy, and 6 (9.2%) had definite stage IV metastasis and/or poor performance status before NAC. Twenty-seven (41.5%) patients underwent IDS followed by HIPEC. The mean duration of IDS with HIPEC was 543.8 (range, 277.0–915.0) minutes. Grade III/IV perioperative complications occurred in 7.4% (n=2)/3.7% (n=1) of patients and no cases of mortality were reported within 30 days postoperatively. The median progression-free survival was 21.3 months, and the median overall survival was not reached for those who received HIPEC.</P><P><B>Conclusions</B></P><P>According to our study protocol, IDS followed by paclitaxel-based HIPEC as a first-line treatment appears to be feasible and safe for the treatment of advanced-stage ovarian cancer. Further evaluations of this procedure are required to assess its survival benefits.</P>
( Hyun Ji Cho ),( Jeong Han Kang ),( Kwan Kyu Park ),( Jung Yoon Choe ),( Yoon Yub Park ),( Yong Suk Moon ),( Ii Kyung Chung ),( Hyeun Wook Chang ),( Cheorl Ho Kim ),( Yung Hyun Choi ),( Wun Jae Kim ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0
BACKGROUND: Bee venom has been used to relieve pain and to treat inflammatory diseases, including rheumatoid arthritis, in humans. To better understand the mechanisms of the anti-inflammatory and anti-atherosclerosis effect of bee venom, gel electrophoresis and mass spectrometry were used to identify proteins whose expression was altered in human Vascular Smooth Muscle Cells (hVSMCs) stimulated by tumor necrosis factor alpha after 12 h in the presence of melittin. RESULTS: To obtain valuable insights into the anti-inflammatory and anti-atherosclerosis mechanisms of melittin, two-dimensional (2-D) gel electrophoresis and MALDI-TOF/TOF were used. The proteomestudy, we showed 33 significant proteins that were differentially expressed in the cells treated withtumor necrosis factor alpha and melittin. Thirteen proteins were significantly increased in the cells treated with tumor necrosis factor alpha, and those proteins were reduced in the cells treated with melittin. Five of the proteins that showed increased expression in the cells treated with tumor necrosisfactor alpha are involved in cell migration, including calreticulin, an essential factor of development that plays a role in transcription regulation. The proteins involved in cell migration were reduced in the melittin treated cells. The observed changes in the expression of GRP75, prohibitin, and a select group of other proteins were validated with reverse transcribed-PCR. It was confirmed that the observed change in the protein levels reflected a change in the genes level. In addition, the phosphorylation of EGFR and ERK was validated by analyzing the protein pathway. CONCLUSION: Taken together, these data established that the expression of some proteins was significantly changed by melittin treatment in tumor necrosis factor alpha stimulated the cells and provided insights into the mechanism of the melittin function for its potential use as an anti-inflammatory agent.
Comparison of single-port laparoscopy and laparotomy in early ovarian cancer surgical staging
( Kyu Hee Cho ),( Yeon Ju Lee ),( Kyung Jin Eoh ),( Yong Jae Lee ),( Jung-yun Lee ),( Eun Ji Nam ),( Sunghoon Kim ),( Young Tae Kim ),( Sang Wun Kim ) 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.1
Objectives The aims of this study were to assess the feasibility of single-port laparoscopic surgical staging (SPLS) in early ovarian cancer and to compare the surgical outcomes of SPLS with those of staging laparotomy. Methods Between January 2014 and December 2018, 40 patients underwent SPLS and 41 patients underwent staging laparotomy at Yonsei Cancer Center. The patients were diagnosed with International Federation of Gynecology and Obstetrics (FIGO) stage I ovarian cancer. Variables such as patient age, body mass index (BMI), tumor size, FIGO stage, and perioperative surgical outcomes and survival outcomes of SPLS and laparotomy were compared. Results The total operation time was similar between the 2 groups (SPLS: 201.4 vs. laparotomy: 203.0 minutes, P=0.806). The median tumor diameters in the SPLS and laparotomy groups were 11.0 (2.5-28 cm) and 15.4 (6-40 cm), respectively (P=0.001). The SPLS group had lower tumor spillage rate (5.0% vs. 19.5%, P=0.047), less intraoperative blood loss (102.0 vs. 371.5 mL, P<0.001), less postoperative pain, and shorter postoperative hospital stay (5 vs. 9.5 days, P<0.001). The intraoperative major complication rate was similar between groups (2.5% vs. 4.9%, P=0.571). There was no significant difference in progression-free survival between the 2 groups (P=0.945). There were no deaths in either group. Conclusion SPLS is feasible in early ovarian cancer and has better perioperative surgical outcomes, in some aspects, than staging laparotomy without compromising survival outcomes. SPLS could be performed in patients suspected to have early ovarian cancer.