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      • KCI등재

        Hierarchical Identity-based Broadcast Encryption Scheme from LWE

        Chunli Yang,Shihui Zheng,Licheng Wang,Xiuhua Lu,Yixian Yang 한국통신학회 2014 Journal of communications and networks Vol.16 No.3

        A hierarchical identity-based broadcast encryption (HIBBE)scheme is an identity-based broadcast encryption (IBBE)scheme in a hierarchical environment. In order to obtain secure HIBBEschemes in the quantum era, we propose an H-IBBE schemebased on the learning with errors problemassumption.Our schemeachieves indistinguishability from random under adaptive chosenplaintextand chosen-identity attacks in the random oracle model.

      • KCI등재

        A bidirectional valveless piezoelectric micropump with three chambers applying synthetic jet

        Xiuhua He,Liang Xu,Xitong Zhang,Song Yang 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.9

        A new type of valveless piezoelectric micropump is presented. Synthetic jet and Coanda effect are utilized to achieve larger and bidirectional flow rate. The numerical simulation applying the velocity and pressure boundary conditions as well as the SST turbulence model were utilized to research the performance and internal flow state of the micropump. The simulation method was tested by the previous experimental data and the results matched well. The results suggest that the flow rate of the micropump is related to the Reynolds number and frequency. The entrainment flow rate of synthetic jet accounts for over 80% of the total outflow rate. The outflow rate is much larger than the volume change of the micropump chambers. There is an optimal frequency to obtain the maximum flow rate regarding the volume change of the chambers as a constant. The fluctuation of the flow rate decreases with the increase of frequency. When the frequency is higher than 25 Hz, the outflow can be continuous. Working at the Reynolds number of 1000 and optimal frequency of 50 Hz, the flow rate is 6.8 ml/min.

      • KCI우수등재

        Effects of dietary copper on organ indexes, tissular Cu, Zn and Fe deposition and fur quality of growing-furring male mink (Mustela vison)

        Wu, Xuezhuang,Gao, Xiuhua,Yang, Fuhe Korean Society of Animal Science and Technology 2015 한국축산학회지 Vol.57 No.2

        The objectives of this study were to study the effects of different levels of dietary copper on organ indexes, tissular Cu, Zn and Fe deposition and fur quality of mink in the growing-furring periods. One hundred and five standard dark male mink were randomly assigned to seven groups with the following dietary treatments: basal diet with no supplemental Cu (Control); basal diet supplemented with either 6, 12, 24, 48, 96 and 192 mg/kg Cu from copper sulphate, respectively. The colour intensity scores displayed a linear trend (P = 0.057). The spleen Cu concentrations responded in a linear (P < 0.05) fashion with increasing level of Cu, but copper supplementation did not affect speen concentrations of Fe or Zn. Supplemental dose of Cu linearly increased (P < 0.05) liver Cu and Fe concentrations but did not alter (P > 0.10) liver Zn. Our results indicate that Cu plays an important role in the pigmentation in growing-furring mink, and supplemental dietary Cu in growing-furring mink improve hair colour, and copper has limited effects on liver mineral deposition.

      • KCI등재

        Astragaloside IV reversed the autophagy and oxidative stress induced by the intestinal microbiota of AIS in mice

        Nan Xu,Pengcheng Kan,Xiuhua Yao,Ping Yang,Jiwei Wang,Lei Xiang,Yu Zhu 한국미생물학회 2018 The journal of microbiology Vol.56 No.11

        Acute ischaemic stroke (AIS) seriously affects patient quality of life. We explored the role of the intestinal microbiota on oxidative stress and autophagy in stroke, and Astragaloside IV (AS-IV) reversed the changes induced by intestinal microbiota. We determined the characteristics of the intestinal microbiota of AIS and transient ischaemic attack (TIA) patients by 16S sequencing and found that the structure and diversity of the intestinal microbiota in patients with AIS and TIA were significantly different from those in healthy subjects. Specifically, the abundance of genus Bifidobacterium, Megamonas, Blautia, Holdemanella, and Clostridium, content of homocysteine and triglyceride was increased significantly, thus it may be as a potential mechanism of AIS and TIA. Furthermore, germ-free mice were infused intracolonically with fecal supernatants of TIA and AIS with/without feed AS-IV for 12 weeks, and we found that the feces of AIS up-regulated the autophagy markers Beclin-1, light chain 3 (LC3)-II and autophagy-related gene (Atg)12, and the expression of reactive oxygen species (ROS) and NADPH oxidase 2/4 (NOX2/4), malondialdehyde (MDA), however, the expression of total antioxidant capacity (T-AOC) and activity of superoxide dismutase (SOD) and glutathione (GSH) was down-regulated in brain tissue, the content of homocysteine and free fatty acids (FFA) in serum of the mice. Meanwhile, AS-IV could reverse the above phenomenon, however, it does not affect the motor function of mice. AS-IV reversed these changes and it may be a potential drug for AIS therapeutics.

      • A Novel FCM Algorithm Incorporating Spatial Information for Color Image Segmentation

        Li Ling,Song Yingwei,Yin Zhongnan,Yang Xiuhua 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.8

        Fuzzy c-means clustering (FCM) with spatial information (FCM_S) is an effective algorithm for image segmentation. However, the FCM_S algorithm is not used for color image segmentation and also it produces over-segmentation results. In this paper, we present a novel fuzzy c-means algorithm named nFCM_S that incorporates spatial information into the membership function and cluster center function for segmentation of color images. Firstly, HSV color space is used for decomposition of color images. Then, to label the data points reliably, a linearly-weighted sum image is calculated on each HSV component before clustering process. Finally, spatial information is incorporated in the standard FCM algorithm and nFCM_S is applied separately on each component of HSV color space. Experiment results have shown that the nFCM_S algorithm achieves competitive segmentation results compared to other FCM-based algorithms.

      • KCI등재

        PFP@PLGA/Cu12Sb4S13-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway

        Dong Tianxiu,Jiang Jian,Zhang Hao,Liu Hongyuan,Zou Xiaomeng,Niu Jiamei,Mao Yingxuan,Zhu Mingwei,Chen Xi,Li Zizhuo,Chen Yaodong,Shi Chunying,Yang Xiuhua 나노기술연구협의회 2021 Nano Convergence Vol.8 No.29

        Hepatocellular carcinoma (HCC) is one of the most malignant tumors in the world, and patients with HCC face a poor prognosis. The conventional therapeutic strategies for HCC have undergone a challenge-riddled evolution owing to side effects and unsatisfactory efficacy. Here, aiming to provide a new method of HCC elimination, we formulated a novel multifunctional nanocapsule (PFP@PLGA/Cu 12 Sb 4 S 13 , PPCu) with applications in contrast-enhanced ultrasound imaging (CEUS) and photothermal therapy (PTT). These PPCu were successfully constructed with an average diameter of 346 nm (polydispersity index, PDI = 0.276). The reinforced contrast ratio of these PPCu was determined by CEUS, revealing their promising applications in image-guided monitoring of HCC treatment. Furthermore, the excellent photoabsorption and biocompatibility indicated by organ H&E staining indicated that PPCu meet quality expectations for use as photothermal transduction agent (PTA). PPCu treatment at 50 °C and higher temperatures efficiently repressed the proliferation, induced the apoptosis and decreased the motility of HCC cells. These effects might have been results of RAS/MAPK/MT-CO1 signaling pathway inhibition. In summary, PPCu were constructed to integrate CEUS and PTT successfully into therapy, which can lead to HCC elimination through RAS/MAPK/MT-CO1 signaling pathway repression.

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